Gene Therapy in a Patient with Sickle Cell Disease von Ribeil, Jean-Antoine, Hacein-Bey-Abina, Salima, Payen, Emmanuel, Magnani, Alessandra, Semeraro, Michaela, Magrin, Elisa, Caccavelli, Laure, Neven, Benedicte, Bourget, Philippe, El Nemer, Wassim, Bartolucci, Pablo, Weber, Leslie, Puy, Hervé, Meritet, Jean-François, Grevent, David, Beuzard, Yves, Chrétien, Stany, Lefebvre, Thibaud, Ross, Robert W, Negre, Olivier, Veres, Gabor, Sandler, Laura, Soni, Sandeep, de Montalembert, Mariane, Blanche, Stéphane, Leboulch, Philippe, Cavazzana, Marina

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Sickle Hemoglobin Confers Tolerance to Plasmodium Infection von Ferreira, Ana, Marguti, Ivo, Bechmann, Ingo, Jeney, Viktória, Chora, Ângelo, Palha, Nuno R., Rebelo, Sofia, Henri, Annie, Beuzard, Yves, Soares, Miguel P.

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Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease von Sabaa, Nathalie, de Franceschi, Lucia, Bonnin, Philippe, Castier, Yves, Malpeli, Giorgio, Debbabi, Haythem, Galaup, Ariane, Maier-Redelsperger, Micheline, Vandermeersch, Sophie, Scarpa, Aldo, Janin, Anne, Levy, Bernard, Girot, Robert, Beuzard, Yves, Leboeuf, Christophe, Henri, Annie, Germain, Stéphane, Dussaule, Jean-Claude, Tharaux, Pierre-Louis

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Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen von Bertheau, Philippe, Turpin, Elisabeth, Rickman, David S, Espié, Marc, de Reyniès, Aurélien, Feugeas, Jean-Paul, Plassa, Louis-François, Soliman, Hany, Varna, Mariana, de Roquancourt, Anne, Lehmann-Che, Jacqueline, Beuzard, Yves, Marty, Michel, Misset, Jean-Louis, Janin, Anne, de Thé, Hugues

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ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice von Stocker, Jonathan W., De Franceschi, Lucia, McNaughton-Smith, Grant A., Corrocher, Roberto, Beuzard, Yves, Brugnara, Carlo

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Permanent and Panerythroid Correction of Murine β Thalassemia by Multiple Lentiviral Integration in Hematopoietic Stem Cells von Imren, Suzan, Payen, Emmanuel, Westerman, Karen A., Pawliuk, Robert, Fabry, Mary E., Eaves, Connie J., Cavilla, Benjamin, Wadsworth, Louis D., Beuzard, Yves, Bouhassira, Eric E., Russell, Robert, London, Irving M., Nagel, Ronald L., Leboulch, Philippe, Humphries, R. Keith

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Abnormal modulation of cell protective systems in response to ischemic/reperfusion injury is important in the development of mouse sickle cell hepatopathy von SICILIANO, Angela, MALPELI, Giorgio, DE FRANCESCHI, Lucia, PLATT, Orah S, LEBOUEF, Christophe, JANIN, Anne, SCARPA, Aldo, OLIVIERI, Oliviero, AMATO, Eliana, CORROCHER, Roberto, BEUZARD, Yves

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Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia von Thompson, Alexis A, Walters, Mark C, Kwiatkowski, Janet, Rasko, John E.J, Ribeil, Jean-Antoine, Hongeng, Suradej, Magrin, Elisa, Schiller, Gary J, Payen, Emmanuel, Semeraro, Michaela, Moshous, Despina, Lefrere, Francois, Puy, Hervé, Bourget, Philippe, Magnani, Alessandra, Caccavelli, Laure, Diana, Jean-Sébastien, Suarez, Felipe, Monpoux, Fabrice, Brousse, Valentine, Poirot, Catherine, Brouzes, Chantal, Meritet, Jean-François, Pondarré, Corinne, Beuzard, Yves, Chrétien, Stany, Lefebvre, Thibaud, Teachey, David T, Anurathapan, Usanarat, Ho, P. Joy, von Kalle, Christof, Kletzel, Morris, Vichinsky, Elliott, Soni, Sandeep, Veres, Gabor, Negre, Olivier, Ross, Robert W, Davidson, David, Petrusich, Alexandria, Sandler, Laura, Asmal, Mohammed, Hermine, Olivier, De Montalembert, Mariane, Hacein-Bey-Abina, Salima, Blanche, Stéphane, Leboulch, Philippe, Cavazzana, Marina

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Haemoglobin and haemoglobinopathies at the forefront in the 21st century von Beuzard, Yves

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Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β(A(T87Q))-Globin Gene von Negre, Olivier, Eggimann, Anne-Virginie, Beuzard, Yves, Ribeil, Jean-Antoine, Bourget, Philippe, Borwornpinyo, Suparerk, Hongeng, Suradej, Hacein-Bey, Salima, Cavazzana, Marina, Leboulch, Philippe, Payen, Emmanuel

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An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia von Dussiot, Michael, Maciel, Thiago T, Fricot, Aurélie, Chartier, Céline, Negre, Olivier, Veiga, Joel, Grapton, Damien, Paubelle, Etienne, Payen, Emmanuel, Beuzard, Yves, Leboulch, Philippe, Ribeil, Jean-Antoine, Arlet, Jean-Benoit, Coté, Francine, Courtois, Geneviève, Ginzburg, Yelena Z, Daniel, Thomas O, Chopra, Rajesh, Sung, Victoria, Hermine, Olivier, Moura, Ivan C

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Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia von Cavazzana-Calvo, Marina, Payen, Emmanuel, Negre, Olivier, Wang, Gary, Hehir, Kathleen, Fusil, Floriane, Down, Julian, Denaro, Maria, Brady, Troy, Westerman, Karen, Cavallesco, Resy, Gillet-Legrand, Beatrix, Caccavelli, Laure, Sgarra, Riccardo, Maouche-Chrétien, Leila, Bernaudin, Françoise, Girot, Robert, Dorazio, Ronald, Mulder, Geert-Jan, Polack, Axel, Bank, Arthur, Soulier, Jean, Larghero, Jérôme, Kabbara, Nabil, Dalle, Bruno, Gourmel, Bernard, Socie, Gérard, Chrétien, Stany, Cartier, Nathalie, Aubourg, Patrick, Fischer, Alain, Cornetta, Kenneth, Galacteros, Frédéric, Beuzard, Yves, Gluckman, Eliane, Bushman, Frederick, Hacein-Bey-Abina, Salima, Leboulch, Philippe

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Heat-shock protein-27, -70 and peroxiredoxin-II show molecular chaperone function in sickle red cells: Evidence from transgenic sickle cell mouse model von Biondani, Andrea, Turrini, Franco, Carta, Franco, Matté, Alessandro, Filippini, Alida, Siciliano, Angela, Beuzard, Yves, De Franceschi, Lucia

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Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial von Magrin, Elisa, Semeraro, Michaela, Hebert, Nicolas, Joseph, Laure, Magnani, Alessandra, Chalumeau, Anne, Gabrion, Aurélie, Roudaut, Cécile, Marouene, Jouda, Lefrere, Francois, Diana, Jean-Sebastien, Denis, Adeline, Neven, Bénédicte, Funck-Brentano, Isabelle, Negre, Olivier, Renolleau, Sylvain, Brousse, Valentine, Kiger, Laurent, Touzot, Fabien, Poirot, Catherine, Bourget, Philippe, El Nemer, Wassim, Blanche, Stéphane, Tréluyer, Jean-Marc, Asmal, Mohammed, Walls, Courtney, Beuzard, Yves, Schmidt, Manfred, Hacein-Bey-Abina, Salima, Asnafi, Vahid, Guichard, Isabelle, Poirée, Maryline, Monpoux, Fabrice, Touraine, Philippe, Brouzes, Chantal, de Montalembert, Mariane, Payen, Emmanuel, Six, Emmanuelle, Ribeil, Jean-Antoine, Miccio, Annarita, Bartolucci, Pablo, Leboulch, Philippe, Cavazzana, Marina

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Interest of a New Method for Free Plasma Heme Related Species Dosages in Sickle Cell Disease and Beta Thalassemia von Kiger, Laurent, Adypagavane, Sandia, Bencheikh, Laura, Hebert, Nicolas, Moutereau, Stephane, Galactéros, Frédéric, Marden, Michael, Beuzard, Yves, Pirenne, France, Bartolucci, Pablo

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HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia von Arlet, Jean-Benoît, Ribeil, Jean-Antoine, Guillem, Flavia, Negre, Olivier, Hazoume, Adonis, Marcion, Guillaume, Beuzard, Yves, Dussiot, Michaël, Moura, Ivan Cruz, Demarest, Samuel, de Beauchêne, Isaure Chauvot, Belaid-Choucair, Zakia, Sevin, Margaux, Maciel, Thiago Trovati, Auclair, Christian, Leboulch, Philippe, Chretien, Stany, Tchertanov, Luba, Baudin-Creuza, Véronique, Seigneuric, Renaud, Fontenay, Michaela, Garrido, Carmen, Hermine, Olivier, Courtois, Geneviève

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A gene therapy approach to regulated delivery of erythropoietin as a function of oxygen tension von Rinsch, C, Régulier, E, Déglon, N, Dalle, B, Beuzard, Y, Aebischer, P

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Stress-induced aberrant splicing of TSG101: association to high tumor grade and p53 status in breast cancers von TURPIN, E, DALLE, B, DE ROQUANCOURT, A, PLASSA, L. F, MARTY, M, JANIN, A, BEUZARD, Y, DE THE, H

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Distribution of Lentiviral Vector Integration Sites in Mice Following Therapeutic Gene Transfer to Treat β-thalassemia von Ronen, Keshet, Negre, Olivier, Roth, Shannah, Colomb, Charlotte, Malani, Nirav, Denaro, Maria, Brady, Troy, Fusil, Floriane, Gillet-Legrand, Beatrix, Hehir, Kathleen, Beuzard, Yves, Leboulch, Philippe, Down, Julian D, Payen, Emmanuel, Bushman, Frederic D

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Correction of Sickle Cell Disease in Transgenic Mouse Models by Gene Therapy von Pawliuk, Robert, Westerman, Karen A., Fabry, Mary E., Payen, Emmanuel, Tighe, Robert, Bouhassira, Eric E., Acharya, Seetharama A., Ellis, James, London, Irving M., Eaves, Connie J., Humphries, R. Keith, Beuzard, Yves, Nagel, Ronald L., Leboulch, Philippe

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