Function, Failure, and the Future Potential of Tregs in Type 1 Diabetes von Bettini, Maria, Bettini, Matthew L.

Volltext

Loss of Epigenetic Modification Driven by the Foxp3 Transcription Factor Leads to Regulatory T Cell Insufficiency von Bettini, Matthew L., Pan, Fan, Bettini, Maria, Finkelstein, David, Rehg, Jerold E., Floess, Stefan, Bell, Bryan D., Ziegler, Steven F., Huehn, Jochen, Pardoll, Drew M., Vignali, Dario A.A.

Volltext

The amphiregulin/EGFR axis has limited contribution in controlling autoimmune diabetes von Raugh, Arielle, Jing, Yi, Bettini, Matthew L., Bettini, Maria

Volltext

Early-life microbiota-immune homeostasis von Reynolds, Hayley M, Bettini, Matthew L

Volltext

Thymic development of gut-microbiota-specific T cells von Zegarra-Ruiz, Daniel F., Kim, Dasom V., Norwood, Kendra, Kim, Myunghoo, Wu, Wan-Jung H., Saldana-Morales, Fatima B., Hill, Andrea A., Majumdar, Shubhabrata, Orozco, Stephanie, Bell, Rickesha, Round, June L., Longman, Randy S., Egawa, Takeshi, Bettini, Matthew L., Diehl, Gretchen E.

Volltext

Critical Role for the Microbiota in CX 3 CR1 + Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses von Kim, Myunghoo, Galan, Carolina, Hill, Andrea A, Wu, Wan-Jung, Fehlner-Peach, Hannah, Song, Hyo Won, Schady, Deborah, Bettini, Matthew L, Simpson, Kenneth W, Longman, Randy S, Littman, Dan R, Diehl, Gretchen E

Volltext

Stability and function of regulatory T cells is maintained by a neuropilin-1–semaphorin-4a axis von Delgoffe, Greg M., Woo, Seng-Ryong, Turnis, Meghan E., Gravano, David M., Guy, Cliff, Overacre, Abigail E., Bettini, Matthew L., Vogel, Peter, Finkelstein, David, Bonnevier, Jody, Workman, Creg J., Vignali, Dario A. A.

Volltext

Host-microbiota interactions shaping T-cell response and tolerance in type 1 diabetes von Majumdar, Shubhabrata, Lin, Yong, Bettini, Matthew L

Volltext

Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape von WOO, Seng-Ryong, TURNIS, Meghan E, TANGSOMBATVISIT, Stephanie, GROSSO, Joseph F, NETTO, George, SMELTZER, Matthew P, CHAUX, Alcides, UTZ, Paul J, WORKMAN, Creg J, PARDOLL, Drew M, KORMAN, Alan J, DRAKE, Charles G, GOLDBERG, Monica V, VIGNALI, Dario A. A, BANKOTI, Jaishree, SELBY, Mark, NIRSCHL, Christopher J, BETTINI, Matthew L, GRAVANO, David M, VOGEL, Peter, LONG LIU, Chih

Volltext

Autoimmune CD4+ T cells fine-tune TCF1 expression to maintain function and survive persistent antigen exposure during diabetes von Aljobaily, Nouf, Allard, Denise, Perkins, Bryant, Raugh, Arielle, Galland, Tessa, Jing, Yi, Stephens, W. Zac, Bettini, Matthew L., Hale, J. Scott, Bettini, Maria

Volltext

T-Cell Receptor/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope von Jing, Yi, Kong, Yuelin, McGinty, John, Blahnik-Fagan, Gabriele, Lee, Thomas, Orozco-Figueroa, Stephanie, Bettini, Matthew L, James, Eddie A, Bettini, Maria

Volltext

Antibody-Mediated Targeting of a Hybrid Insulin Peptide Toward Neonatal Thymic Langerin-Positive Cells Enhances T-Cell Central Tolerance and Delays Autoimmune Diabetes von Lin, Yong, Perovanovic, Jelena, Kong, Yuelin, Igyarto, Botond Z, Zurawski, Sandra, Tantin, Dean, Zurawski, Gerard, Bettini, Maria, Bettini, Matthew L

Volltext

A dormant T‐cell population with autoimmune potential exhibits low self‐reactivity and infiltrates islets in type 1 diabetes von Kong, Yuelin, Jing, Yi, Allard, Denise, Scavuzzo, Marissa A., Sprouse, Maran L., Borowiak, Malgorzata, Bettini, Matthew L., Bettini, Maria

Volltext

A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells von Bettini, Maria, Scavuzzo, Marissa A., Liu, Baoyu, Kolawole, Elizabeth, Guo, Lin, Evavold, Brian D., Borowiak, Malgorzata, Bettini, Matthew L.

Volltext

Ectopic Expression of Self-Antigen Drives Regulatory T Cell Development and Not Deletion of Autoimmune T Cells von Lee, Thomas, Sprouse, Maran L, Banerjee, Pinaki, Bettini, Maria, Bettini, Matthew L

Volltext

Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity von Sprouse, Maran L, Shevchenko, Ivan, Scavuzzo, Marissa A, Joseph, Faith, Lee, Thomas, Blum, Samuel, Borowiak, Malgorzata, Bettini, Matthew L, Bettini, Maria

Volltext

Understanding Autoimmune Diabetes through the Prism of the Tri-Molecular Complex von Bettini, Matthew L, Bettini, Maria

Volltext

Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development von Ramstead, Andrew G., Wallace, Jared A., Lee, Soh-Hyun, Bauer, Kaylyn M., Tang, William W., Ekiz, H. Atakan, Lane, Thomas E., Cluntun, Ahmad A., Bettini, Matthew L., Round, June L., Rutter, Jared, O’Connell, Ryan M.

Volltext

Distinct TCR signaling pathways drive proliferation and cytokine production in T cells von Guy, Clifford S, Vignali, Kate M, Temirov, Jamshid, Bettini, Matthew L, Overacre, Abigail E, Smeltzer, Matthew, Zhang, Hui, Huppa, Johannes B, Tsai, Yu-Hwai, Lobry, Camille, Xie, Jianming, Dempsey, Peter J, Crawford, Howard C, Aifantis, Iannis, Davis, Mark M, Vignali, Dario A A

Volltext

Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice von Shrestha, Amrit Kumar, Bettini, Matthew L, Menon, Renuka T, Gopal, Vashisht Y N, Huang, Shixia, Edwards, Dean P, Pammi, Mohan, Barrios, Roberto, Shivanna, Binoy

Volltext