Three-Dimensional Study of Alzheimer’s Disease Hallmarks Using the iDISCO Clearing Method von Liebmann, Thomas, Renier, Nicolas, Bettayeb, Karima, Greengard, Paul, Tessier-Lavigne, Marc, Flajolet, Marc

Volltext

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease von Greengard, Paul, He, Gen, Luo, Wenjie, Li, Peng, Remmers, Christine, Netzer, William J, Hendrick, Joseph, Bettayeb, Karima, Flajolet, Marc, Gorelick, Fred, Wennogle, Lawrence P

Volltext

Meriolins (3-(Pyrimidin-4-yl)-7-azaindoles): Synthesis, Kinase Inhibitory Activity, Cellular Effects, and Structure of a CDK2/Cyclin A/Meriolin Complex von Echalier, Aude, Bettayeb, Karima, Ferandin, Yoan, Lozach, Olivier, Clément, Monique, Valette, Annie, Liger, François, Marquet, Bernard, Morris, Jonathan C, Endicott, Jane A, Joseph, Benoît, Meijer, Laurent

Volltext

N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine von Bettayeb, Karima, Sallam, Hatem, Ferandin, Yoan, Popowycz, Florence, Fournet, Guy, Hassan, Moustapha, Echalier, Aude, Bernard, Philippe, Endicott, Jane, Joseph, Benoît, Meijer, Laurent

Volltext

GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease von Xu, Peng, Chang, Jerry C, Zhou, Xiaopu, Wang, Wei, Bamkole, Michael, Wong, Eitan, Bettayeb, Karima, Jiang, Lu-Lin, Huang, Timothy, Luo, Wenjie, Xu, Huaxi, Nairn, Angus C, Flajolet, Marc, Ip, Nancy Y, Li, Yue-Ming, Greengard, Paul

Volltext

Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage von Netzer, William J., Bettayeb, Karima, Sinha, Subhash C., Flajolet, Marc, Greengard, Paul, Bustos, Victor

Volltext

Gleevec shifts APP processing from a [Beta]-cleavage to a nonamyloidogenic cleavage von Netzer, William J, Bettayeb, Karima, Sinha, Subhash C, Flajolet, Marc, Greengard, Paul, Bustos, Victor

Volltext

δ-COP modulates Aβ peptide formation via retrograde trafficking of APP von Bettayeb, Karima, Chang, Jerry C., Luo, Wenjie, Aryal, Suvekshya, Varotsis, Dante, Randolph, Lisa, Netzer, William J., Greengard, Paul, Flajolet, Marc

Volltext

Relevance of the COPI complex for Alzheimer’s disease progression in vivo von Bettayeb, Karima, Hooli, Basaraj V., Parrado, Antonio R., Randolph, Lisa, Varotsis, Dante, Aryal, Suvekshya, Gresack, Jodi, Tanzi, Rudolph E., Greengard, Paul, Flajolet, Marc

Volltext

Soluble 3′,6-Substituted Indirubins with Enhanced Selectivity toward Glycogen Synthase Kinase -3 Alter Circadian Period von Vougogiannopoulou, Konstantina, Ferandin, Yoan, Bettayeb, Karima, Myrianthopoulos, Vassilios, Lozach, Olivier, Fan, Yunzhen, Johnson, Carl Hirschie, Magiatis, Prokopios, Skaltsounis, Alexios-Leandros, Mikros, Emmanuel, Meijer, Laurent

Volltext

[delta]-COP modulates A[Beta] peptide formation via retrograde trafficking of APP von Bettayeb, Karima, Chang, Jerry C, Luo, Wenjie, Aryal, Suvekshya, Varotsis, Dante, Randolph, Lisa, Netzer, William J, Greengard, Paul, Flajolet, Marc

Volltext

Small‐molecule inducers of Aβ‐42 peptide production share a common mechanism of action von Bettayeb, Karima, Oumata, Nassima, Zhang, Yuanyuan, Luo, Wenjie, Bustos, Victor, Galons, Hervé, Greengard, Paul, Meijer, Laurent, Flajolet, Marc

Volltext

Roscovitine-Derived, Dual-Specificity Inhibitors of Cyclin-Dependent Kinases and Casein Kinases 1 von Oumata, Nassima, Bettayeb, Karima, Ferandin, Yoan, Demange, Luc, Lopez-Giral, Angela, Goddard, Marie-Lorène, Myrianthopoulos, Vassilios, Mikros, Emmanuel, Flajolet, Marc, Greengard, Paul, Meijer, Laurent, Galons, Hervé

Volltext

Pyrazolo[1,5-a]-1,3,5-triazine as a Purine Bioisostere: Access to Potent Cyclin-Dependent Kinase Inhibitor (R)-Roscovitine Analogue von Popowycz, Florence, Fournet, Guy, Schneider, Cédric, Bettayeb, Karima, Ferandin, Yoan, Lamigeon, Cyrile, Tirado, Oscar M, Mateo-Lozano, Silvia, Notario, Vicente, Colas, Pierre, Bernard, Philippe, Meijer, Laurent, Joseph, Benoît

Volltext

3‘-Substituted 7-Halogenoindirubins, a New Class of Cell Death Inducing Agents von Ferandin, Yoan, Bettayeb, Karima, Kritsanida, Marina, Lozach, Olivier, Polychronopoulos, Panagiotis, Magiatis, Prokopios, Skaltsounis, Alexios-Leandros, Meijer, Laurent

Volltext

Synthesis and biological evaluation of selective and potent cyclin-dependent kinase inhibitors von N'gompaza-Diarra, Joannah, Bettayeb, Karima, Gresh, Nohad, Meijer, Laurent, Oumata, Nassima

Volltext

Meriolins, a new class of cell death -Inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases von BETTAYEB, Karima, TIRADE, Oscar M, LIGER, Francois, MARQUET, Bernard, JOSEPH, Benoit, ECHALIER, Aude, ENDICOTT, Jane A, NOTARIO, Vicente, MEIJER, Laurent, MARIONNEAU-LAMBOT, Séverine, FERANDIN, Yoan, LOZACH, Olivier, MORRIS, Jonathan C, MATEO-LOZANO, Silvia, DRUECKES, Peter, SCHÄCHTELE, Christoph, KUBBUTAT, Michael H. G

Volltext

CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells von Bettayeb, Karima, Baunbæk, Dianne, Delehouze, Claire, Loaëc, Nadège, Hole, Alison J, Baumli, Sonja, Endicott, Jane A, Douc-Rasy, Setha, Bénard, Jean, Oumata, Nassima, Galons, Hervé, Meijer, Laurent

Volltext

Schéma posologique par titration de l’aducanumab : analyse à 24 mois de Prime, une étude de phase 1b randomisée, en double insu, contrôlée par placebo chez des patients atteints de... von O’gorman, John, Von Rosenstiel, Philipp, Gheuens, Sarah, Chiao, Ping, Nitsch, Roger, Sandrock, Alfred, Bettayeb, Karima

Volltext

New cyclin-dependant kinase inhibitors as potential anti-tumor agents von Galons, Hervé, Meijer, Laurent, Oumata, Nassima, Bettayeb, Karima

Volltext