Mechanisms and Consequences of Macromolecular Phase Separation von Bergeron-Sandoval, Louis-Philippe, Safaee, Nozhat, Michnick, Stephen W.

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Mechanics, Structure and Function of Biopolymer Condensates von Bergeron-Sandoval, Louis-Philippe, Michnick, Stephen W.

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A Cell-Signaling Network Temporally Resolves Specific versus Promiscuous Phosphorylation von Kanshin, Evgeny, Bergeron-Sandoval, Louis-Philippe, Isik, S. Sinan, Thibault, Pierre, Michnick, Stephen W.

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Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors von Kschonsak, Marc, Jao, Christine C, Arthur, Christopher P, Rohou, Alexis L, Bergeron, Philippe, Ortwine, Daniel F, McKerrall, Steven J, Hackos, David H, Deng, Lunbin, Chen, Jun, Li, Tianbo, Dragovich, Peter S, Volgraf, Matthew, Wright, Matthew R, Payandeh, Jian, Ciferri, Claudio, Tellis, John C

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Endocytic proteins with prion-like domains form viscoelastic condensates that enable membrane remodeling von Bergeron-Sandoval, Louis-Philippe, Kumar, Sandeep, Heris, Hossein Khadivi, Chang, Catherine L. A., Cornell, Caitlin E., Keller, Sarah L., François, Paul, Hendricks, Adam G., Ehrlicher, Allen J., Pappu, Rohit V., Michnick, Stephen W.

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Why does biopolymer condensation matter? von Michnick, Stephen W., Bergeron-Sandoval, Louis-Philippe

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Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres von Cohen, Frederick, Koehler, Michael F.T., Bergeron, Philippe, Elliott, Linda O., Flygare, John A., Franklin, Matthew C., Gazzard, Lewis, Keteltas, Stephen F., Lau, Kevin, Ly, Cuong Q., Tsui, Vickie, Fairbrother, Wayne J.

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Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations von Johnson, Adam R, Kohli, Pawan Bir, Katewa, Arna, Gogol, Emily, Belmont, Lisa D, Choy, Regina, Penuel, Elicia, Burton, Luciana, Eigenbrot, Charles, Yu, Christine, Ortwine, Daniel F, Bowman, Krista, Franke, Yvonne, Tam, Christine, Estevez, Alberto, Mortara, Kyle, Wu, Jiansheng, Li, Hong, Lin, May, Bergeron, Philippe, Crawford, James J, Young, Wendy B

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Discovery of Acyl-sulfonamide Na(v)1.7 Inhibitors GDC-0276 and GDC-0310 von Safina, Brian S., McKerrall, Steven J., Sun, Shaoyi, Chen, Chien-An, Chowdhury, Sultan, Jia, Qi, Li, Jun, Zenova, Alla Y., Andrez, Jean-Christophe, Bankar, Girish, Bergeron, Philippe, Chang, Jae H., Chang, Elaine, Chen, Jun, Dean, Richard, Decker, Shannon M., DiPasquale, Antonio, Focken, Thilo, Hemeon, Ivan, Khakh, Kuldip, Kim, Amy, Kwan, Rainbow, Lindgren, Andrea, Lin, Sophia, Maher, Jonathan, Mezeyova, Janette, Misner, Dinah, Nelkenbrecher, Karen, Pang, Jodie, Reese, Rebecca, Shields, Shannon D., Sojo, Luis, Sheng, Tao, Verschoof, Henry, Waldbrook, Matthew, Wilson, Michael S., Xie, Zhiwei, Young, Clint, Zabka, Tanja S., Hackos, David H., Ortwine, Daniel F., White, Andrew D., Johnson, J. P., Robinette, C. Lee, Dehnhardt, Christoph M., Cohen, Charles J., Sutherlin, Daniel P.

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Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Nav1.7 Inhibitors for the Treatment of Chronic Pain von McKerrall, Steven J, Nguyen, Teresa, Lai, Kwong Wah, Bergeron, Philippe, Deng, Lunbin, DiPasquale, Antonio, Chang, Jae H, Chen, Jun, Chernov-Rogan, Tania, Hackos, David H, Maher, Jonathan, Ortwine, Daniel F, Pang, Jodie, Payandeh, Jian, Proctor, William R, Shields, Shannon D, Vogt, Jennifer, Ji, Pengfei, Liu, Wenfeng, Ballini, Elisa, Schumann, Lilia, Tarozzo, Glauco, Bankar, Girish, Chowdhury, Sultan, Hasan, Abid, Johnson, J. P, Khakh, Kuldip, Lin, Sophia, Cohen, Charles J, Dehnhardt, Christoph M, Safina, Brian S, Sutherlin, Daniel P

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Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells von Koehler, Michael F. T, Bergeron, Philippe, Blackwood, Elizabeth M, Bowman, Krista, Clark, Kevin R, Firestein, Ron, Kiefer, James R, Maskos, Klaus, McCleland, Mark L, Orren, Linda, Salphati, Laurent, Schmidt, Steve, Schneider, Elisabeth V, Wu, Jiansheng, Beresini, Maureen H

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Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 and GDC-0310 von Safina, Brian S, McKerrall, Steven J, Sun, Shaoyi, Chen, Chien-An, Chowdhury, Sultan, Jia, Qi, Li, Jun, Zenova, Alla Y, Andrez, Jean-Christophe, Bankar, Girish, Bergeron, Philippe, Chang, Jae H, Chang, Elaine, Chen, Jun, Dean, Richard, Decker, Shannon M, DiPasquale, Antonio, Focken, Thilo, Hemeon, Ivan, Khakh, Kuldip, Kim, Amy, Kwan, Rainbow, Lindgren, Andrea, Lin, Sophia, Maher, Jonathan, Mezeyova, Janette, Misner, Dinah, Nelkenbrecher, Karen, Pang, Jodie, Reese, Rebecca, Shields, Shannon D, Sojo, Luis, Sheng, Tao, Verschoof, Henry, Waldbrook, Matthew, Wilson, Michael S, Xie, Zhiwei, Young, Clint, Zabka, Tanja S, Hackos, David H, Ortwine, Daniel F, White, Andrew D, Johnson, J.P, Robinette, C. Lee, Dehnhardt, Christoph M, Cohen, Charles J, Sutherlin, Daniel P

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Flagellin produced in plants is a potent adjuvant for oral immunization von Girard, Aurélie, Saron, Wilfried, Bergeron-Sandoval, Louis-Philippe, Sarhan, Fathey, Archambault, Denis

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Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8 von Bergeron, Philippe, Koehler, Michael F. T, Blackwood, Elizabeth M, Bowman, Krista, Clark, Kevin, Firestein, Ron, Kiefer, James R, Maskos, Klaus, McCleland, Mark L, Orren, Linda, Ramaswamy, Sreemathy, Salphati, Laurent, Schmidt, Steve, Schneider, Elisabeth V, Wu, Jiansheng, Beresini, Maureen

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Discovery of Acyl-sulfonamide Na v 1.7 Inhibitors GDC-0276 and GDC-0310 von Safina, Brian S, McKerrall, Steven J, Sun, Shaoyi, Chen, Chien-An, Chowdhury, Sultan, Jia, Qi, Li, Jun, Zenova, Alla Y, Andrez, Jean-Christophe, Bankar, Girish, Bergeron, Philippe, Chang, Jae H, Chang, Elaine, Chen, Jun, Dean, Richard, Decker, Shannon M, DiPasquale, Antonio, Focken, Thilo, Hemeon, Ivan, Khakh, Kuldip, Kim, Amy, Kwan, Rainbow, Lindgren, Andrea, Lin, Sophia, Maher, Jonathan, Mezeyova, Janette, Misner, Dinah, Nelkenbrecher, Karen, Pang, Jodie, Reese, Rebecca, Shields, Shannon D, Sojo, Luis, Sheng, Tao, Verschoof, Henry, Waldbrook, Matthew, Wilson, Michael S, Xie, Zhiwei, Young, Clint, Zabka, Tanja S, Hackos, David H, Ortwine, Daniel F, White, Andrew D, Johnson, Jr, J P, Robinette, C Lee, Dehnhardt, Christoph M, Cohen, Charles J, Sutherlin, Daniel P

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Identification of C‑2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2 von Zak, Mark, Hurley, Christopher A, Ward, Stuart I, Bergeron, Philippe, Barrett, Kathy, Balazs, Mercedesz, Blair, Wade S, Bull, Richard, Chakravarty, Paroma, Chang, Christine, Crackett, Peter, Deshmukh, Gauri, DeVoss, Jason, Dragovich, Peter S, Eigenbrot, Charles, Ellwood, Charles, Gaines, Simon, Ghilardi, Nico, Gibbons, Paul, Gradl, Stefan, Gribling, Peter, Hamman, Chris, Harstad, Eric, Hewitt, Peter, Johnson, Adam, Johnson, Tony, Kenny, Jane R, Koehler, Michael F. T, Bir Kohli, Pawan, Labadie, Sharada, Lee, Wyne P, Liao, Jiangpeng, Liimatta, Marya, Mendonca, Rohan, Narukulla, Raman, Pulk, Rebecca, Reeve, Austin, Savage, Scott, Shia, Steven, Steffek, Micah, Ubhayakar, Savita, van Abbema, Anne, Aliagas, Ignacio, Avitabile-Woo, Barbara, Xiao, Yisong, Yang, Jing, Kulagowski, Janusz J

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Dynamic FLNa and FilGAP Binding Is Required for Contractile Mechanotransduction Response to Shear-Stress von Bergeron-Sandoval, Louis-Philippe, Ehrlicher, Allen J.

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Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Na v 1.7 Inhibitors for the Treatment of Chronic Pain von McKerrall, Steven J, Nguyen, Teresa, Lai, Kwong Wah, Bergeron, Philippe, Deng, Lunbin, DiPasquale, Antonio, Chang, Jae H, Chen, Jun, Chernov-Rogan, Tania, Hackos, David H, Maher, Jonathan, Ortwine, Daniel F, Pang, Jodie, Payandeh, Jian, Proctor, William R, Shields, Shannon D, Vogt, Jennifer, Ji, Pengfei, Liu, Wenfeng, Ballini, Elisa, Schumann, Lilia, Tarozzo, Glauco, Bankar, Girish, Chowdhury, Sultan, Hasan, Abid, Johnson, Jr, J P, Khakh, Kuldip, Lin, Sophia, Cohen, Charles J, Dehnhardt, Christoph M, Safina, Brian S, Sutherlin, Daniel P

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Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2 von Zak, Mark, Mendonca, Rohan, Balazs, Mercedesz, Barrett, Kathy, Bergeron, Philippe, Blair, Wade S, Chang, Christine, Deshmukh, Gauri, DeVoss, Jason, Dragovich, Peter S, Eigenbrot, Charles, Ghilardi, Nico, Gibbons, Paul, Gradl, Stefan, Hamman, Chris, Hanan, Emily J, Harstad, Eric, Hewitt, Peter R, Hurley, Christopher A, Jin, Tian, Johnson, Adam, Johnson, Tony, Kenny, Jane R, Koehler, Michael F. T, Bir Kohli, Pawan, Kulagowski, Janusz J, Labadie, Sharada, Liao, Jiangpeng, Liimatta, Marya, Lin, Zhonghua, Lupardus, Patrick J, Maxey, Robert J, Murray, Jeremy M, Pulk, Rebecca, Rodriguez, Madeleine, Savage, Scott, Shia, Steven, Steffek, Micah, Ubhayakar, Savita, Ultsch, Mark, van Abbema, Anne, Ward, Stuart I, Xiao, Ling, Xiao, Yisong

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A hit to lead discovery of novel N-methylated imidazolo-, pyrrolo-, and pyrazolo-pyrimidines as potent and selective mTOR inhibitors von Lee, Wendy, Ortwine, Daniel F., Bergeron, Philippe, Lau, Kevin, Lin, Lichuan, Malek, Shiva, Nonomiya, Jim, Pei, Zhonghua, Robarge, Kirk D., Schmidt, Stephen, Sideris, Steve, Lyssikatos, Joseph P.

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