The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis von Woodcock, Hannah V., Eley, Jessica D., Guillotin, Delphine, Platé, Manuela, Nanthakumar, Carmel B., Martufi, Matteo, Peace, Simon, Joberty, Gerard, Poeckel, Daniel, Good, Robert B., Taylor, Adam R., Zinn, Nico, Redding, Matthew, Forty, Ellen J., Hynds, Robert E., Swanton, Charles, Karsdal, Morten, Maher, Toby M., Fisher, Andrew, Bergamini, Giovanna, Marshall, Richard P., Blanchard, Andy D., Mercer, Paul F., Chambers, Rachel C.

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Systematic analysis of protein turnover in primary cells von Mathieson, Toby, Franken, Holger, Kosinski, Jan, Kurzawa, Nils, Zinn, Nico, Sweetman, Gavain, Poeckel, Daniel, Ratnu, Vikram S., Schramm, Maike, Becher, Isabelle, Steidel, Michael, Noh, Kyung-Min, Bergamini, Giovanna, Beck, Martin, Bantscheff, Marcus, Savitski, Mikhail M.

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Identifying drug targets in tissues and whole blood with thermal-shift profiling von Perrin, Jessica, Werner, Thilo, Kurzawa, Nils, Rutkowska, Anna, Childs, Dorothee D., Kalxdorf, Mathias, Poeckel, Daniel, Stonehouse, Eugenia, Strohmer, Katrin, Heller, Bianca, Thomson, Douglas W., Krause, Jana, Becher, Isabelle, Eberl, H. Christian, Vappiani, Johanna, Sevin, Daniel C., Rau, Christina E., Franken, Holger, Huber, Wolfgang, Faelth-Savitski, Maria, Savitski, Mikhail M., Bantscheff, Marcus, Bergamini, Giovanna

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Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes von Bantscheff, Marcus, Hopf, Carsten, Savitski, Mikhail M, Dittmann, Antje, Grandi, Paola, Michon, Anne-Marie, Schlegl, Judith, Abraham, Yann, Becher, Isabelle, Bergamini, Giovanna, Boesche, Markus, Delling, Manja, Dümpelfeld, Birgit, Eberhard, Dirk, Huthmacher, Carola, Mathieson, Toby, Poeckel, Daniel, Reader, Valérie, Strunk, Katja, Sweetman, Gavain, Kruse, Ulrich, Neubauer, Gitte, Ramsden, Nigel G, Drewes, Gerard

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Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors von Klaeger, Susan, Gohlke, Bjoern, Perrin, Jessica, Gupta, Vipul, Heinzlmeir, Stephanie, Helm, Dominic, Qiao, Huichao, Bergamini, Giovanna, Handa, Hiroshi, Savitski, Mikhail M, Bantscheff, Marcus, Médard, Guillaume, Preissner, Robert, Kuster, Bernhard

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Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition von Burtscher, Mira L, Gade, Stephan, Garrido-Rodriguez, Martin, Rutkowska, Anna, Werner, Thilo, Eberl, H Christian, Petretich, Massimo, Knopf, Natascha, Zirngibl, Katharina, Grandi, Paola, Bergamini, Giovanna, Bantscheff, Marcus, Fälth-Savitski, Maria, Saez-Rodriguez, Julio

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Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis von Woodcock, Hannah V., Eley, Jessica D., Guillotin, Delphine, Platé, Manuela, Nanthakumar, Carmel B., Martufi, Matteo, Peace, Simon, Joberty, Gerard, Poeckel, Daniel, Good, Robert B., Taylor, Adam R., Zinn, Nico, Redding, Matthew, Forty, Ellen J., Hynds, Robert E., Swanton, Charles, Karsdal, Morten, Maher, Toby M., Fisher, Andrew, Bergamini, Giovanna, Marshall, Richard P., Blanchard, Andy D., Mercer, Paul F., Chambers, Rachel C.

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Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor von Thomson, Douglas W, Poeckel, Daniel, Zinn, Nico, Rau, Christina, Strohmer, Katrin, Wagner, Anne J, Graves, Alan P, Perrin, Jessica, Bantscheff, Marcus, Duempelfeld, Birgit, Kasparcova, Viera, Ramanjulu, Joshi M, Pesiridis, G. Scott, Muelbaier, Marcel, Bergamini, Giovanna

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Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system von BERGAMINI, GIOVANNA, PREISS, THOMAS, HENTZE, MATTHIAS W.

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Enhancement of IRES-Mediated Translation of the c- myc and BiP mRNAs by the Poly(A) Tail Is Independent of Intact eIF4G and PABP von Thoma, Christian, Bergamini, Giovanna, Galy, Bruno, Hundsdoerfer, Patrick, Hentze, Matthias W.

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Drug Target Identification in Tissues by Thermal Proteome Profiling von Mateus, André, Kurzawa, Nils, Perrin, Jessica, Bergamini, Giovanna, Savitski, Mikhail M

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Design of amidobenzimidazole STING receptor agonists with systemic activity von Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, Bertin, John

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Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis von Savitski, Mikhail M., Zinn, Nico, Faelth-Savitski, Maria, Poeckel, Daniel, Gade, Stephan, Becher, Isabelle, Muelbaier, Marcel, Wagner, Anne J., Strohmer, Katrin, Werner, Thilo, Melchert, Stephanie, Petretich, Massimo, Rutkowska, Anna, Vappiani, Johanna, Franken, Holger, Steidel, Michael, Sweetman, Gavain M., Gilan, Omer, Lam, Enid Y.N., Dawson, Mark A., Prinjha, Rab K., Grandi, Paola, Bergamini, Giovanna, Bantscheff, Marcus

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Catalytic in vivo protein knockdown by small-molecule PROTACs von Bondeson, Daniel P, Mares, Alina, Smith, Ian E D, Ko, Eunhwa, Campos, Sebastien, Miah, Afjal H, Mulholland, Katie E, Routly, Natasha, Buckley, Dennis L, Gustafson, Jeffrey L, Zinn, Nico, Grandi, Paola, Shimamura, Satoko, Bergamini, Giovanna, Faelth-Savitski, Maria, Bantscheff, Marcus, Cox, Carly, Gordon, Deborah A, Willard, Ryan R, Flanagan, John J, Casillas, Linda N, Votta, Bartholomew J, den Besten, Willem, Famm, Kristoffer, Kruidenier, Laurens, Carter, Paul S, Harling, John D, Churcher, Ian, Crews, Craig M

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A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level von Rutkowska, Anna, Thomson, Douglas W, Vappiani, Johanna, Werner, Thilo, Mueller, Katrin M, Dittus, Lars, Krause, Jana, Muelbaier, Marcel, Bergamini, Giovanna, Bantscheff, Marcus

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An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices von Khan, Muzamil Majid, Poeckel, Daniel, Halavatyi, Aliaksandr, Zukowska-Kasprzyk, Joanna, Stein, Frank, Vappiani, Johanna, Sevin, Daniel C, Tischer, Christian, Zinn, Nico, Eley, Jessica D, Gudmann, Natasja Stæhr, Muley, Thomas, Winter, Hauke, Fisher, Andrew J, Nanthakumar, Carmel B, Bergamini, Giovanna, Pepperkok, Rainer

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A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation von Bergamini, Giovanna, Bell, Kathryn, Shimamura, Satoko, Werner, Thilo, Cansfield, Andrew, Müller, Katrin, Perrin, Jessica, Rau, Christina, Ellard, Katie, Hopf, Carsten, Doce, Carola, Leggate, Daniel, Mangano, Raffaella, Mathieson, Toby, O'Mahony, Alison, Plavec, Ivan, Rharbaoui, Faiza, Reinhard, Friedrich, Savitski, Mikhail M, Ramsden, Nigel, Hirsch, Emilio, Drewes, Gerard, Rausch, Oliver, Bantscheff, Marcus, Neubauer, Gitte

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A selective inhibitor reveals PI3Kγ dependence of TH17 cell differentiation von Bergamini, Giovanna, Bell, Kathryn, Shimamura, Satoko, Werner, Thilo, Cansfield, Andrew, Müller, Katrin, Perrin, Jessica, Rau, Christina, Ellard, Katie, Hopf, Carsten, Doce, Carola, Leggate, Daniel, Mangano, Raffaella, Mathieson, Toby, O'Mahony, Alison, Plavec, Ivan, Rharbaoui, Faiza, Reinhard, Friedrich, Savitski, Mikhail M, Ramsden, Nigel, Hirsch, Emilio, Drewes, Gerard, Rausch, Oliver, Bantscheff, Marcus, Neubauer, Gitte

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Characterization of Apo‐Form Selective Inhibition of Indoleamine 2,3‐Dioxygenase von Ortiz‐Meoz, Rodrigo F., Wang, Liping, Matico, Rosalie, Rutkowska‐Klute, Anna, De la Rosa, Martha, Bedard, Sabrina, Midgett, Robert, Strohmer, Katrin, Thomson, Douglas, Zhang, Cunyu, Mebrahtu, Makda, Guss, Jeffrey, Totoritis, Rachel, Consler, Thomas, Campobasso, Nino, Taylor, David, Lewis, Tia, Weaver, Kurt, Muelbaier, Marcel, Seal, John, Dunham, Richard, Kazmierski, Wieslaw, Favre, David, Bergamini, Giovanna, Shewchuk, Lisa, Rendina, Alan, Zhang, Guofeng

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Thoughts for the future von Alkhalaf, Lona M., Arrowsmith, Cheryl, Balskus, Emily P., Bergamini, Giovanna, Bhandari, Rashna, Chang, Christopher J., Chen, Peng, Chen, Xing, Ciulli, Alessio, Cricco, Julia A., Davis, Benjamin G., Delbianco, Martina, Dudareva, Natalia, Dueber, Erin, Ferguson, Fleur, de Giuseppe, Priscila Oliveira, Hamachi, Itaru, Hammond, Ming Chen, Hatzios, Stavroula K., Do Heo, Won, Janet, Jon Paul, Kamat, Siddhesh S., Knapp, Stefan, Krishnan, Yamuna, Lang, Kathrin, Laraia, Luca, Leveson-Gower, Reuben B., Li, Xiang David, Liu, David R., Liu, Mo-Fang, London, Nir, Mahanta, Nilkamal, Mayor-Ruiz, Cristina, Muir, Tom, Murakami, Mário Tyago, Rhee, Hyun-Woo, Robers, Matt, Satz, Alex, Schulman, Brenda A., Shen, Ben, Shoichet, Brian, Strauss, Erick, Suzuki, Tsutomu, Tiwary, Pratyush, Waldmann, Herbert, Ward, Thomas R., Weeks, Amy, Weerapana, Eranthie, Winter, Georg

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