Discovery of a Photoaffinity Probe that Captures the Active Conformation of the Cannabinoid CB2 Receptor von De Paus, Laura V., An, Yu, Janssen, Antonius P. A., Berg, Richard J. B. H. N., Heitman, Laura H., Stelt, Mario

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Structural basis of selective cannabinoid CB2 receptor activation von Li, Xiaoting, Chang, Hao, Bouma, Jara, de Paus, Laura V., Mukhopadhyay, Partha, Paloczi, Janos, Mustafa, Mohammed, van der Horst, Cas, Kumar, Sanjay Sunil, Wu, Lijie, Yu, Yanan, van den Berg, Richard J. B. H. N., Janssen, Antonius P. A., Lichtman, Aron, Liu, Zhi-Jie, Pacher, Pal, van der Stelt, Mario, Heitman, Laura H., Hua, Tian

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Glycosphingolipids-Nature, Function, and Pharmacological Modulation von Wennekes, Tom, van den Berg, Richard J. B. H. N., Boot, Rolf G., van der Marel, Gijsbert A., Overkleeft, Herman S., Aerts, Johannes M. F. G.

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Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria von Bakker, Alexander T., Kotsogianni, Ioli, Avalos, Mariana, Punt, Jeroen M., Liu, Bing, Piermarini, Diana, Gagestein, Berend, Slingerland, Cornelis J., Zhang, Le, Willemse, Joost J., Ghimire, Leela B., van den Berg, Richard J. H. B. N., Janssen, Antonius P. A., Ottenhoff, Tom H. M., van Boeckel, Constant A. A., van Wezel, Gilles P., Ghilarov, Dmitry, Martin, Nathaniel I., van der Stelt, Mario

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Development of Adamantan-1-yl-methoxy-Functionalized 1-Deoxynojirimycin Derivatives as Selective Inhibitors of Glucosylceramide Metabolism in Man von Wennekes, Tom, van den Berg, Richard J. B. H. N, Donker, Wilma, van der Marel, Gijsbert A, Strijland, Anneke, Aerts, Johannes M. F. G, Overkleeft, Herman S

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Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding von Deng, Hui, Kooijman, Sander, van den Nieuwendijk, Adrianus M. C. H, Ogasawara, Daisuke, van der Wel, Tom, van Dalen, Floris, Baggelaar, Marc P, Janssen, Freek J, van den Berg, Richard J. B. H. N, den Dulk, Hans, Cravatt, Benjamin F, Overkleeft, Herman S, Rensen, Patrick C. N, van der Stelt, Mario

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The Development of an Aza-C-Glycoside Library Based on a Tandem Staudinger/Aza-Wittig/Ugi Three-Component Reaction von Wennekes, Tom, Bonger, Kimberly M., Vogel, Katrin, van den Berg, Richard J. B. H. N., Strijland, Anneke, Donker-Koopman, Wilma E., Aerts, Johannes M. F. G., van der Marel, Gijsbert A., Overkleeft, Herman S.

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Synthesis of l-altro-1-Deoxynojirimycin, d-allo-1-Deoxynojirimycin, and d-galacto-1-Deoxynojirimycin from a Single Chiral Cyanohydrin von van den Nieuwendijk, Adrianus M. C. H, Ruben, Mark, Engelsma, Sander E, Risseeuw, Martijn D. P, van den Berg, Richard J. B. H. N, Boot, Rolf G, Aerts, Johannes M, Brussee, Johannes, van der Marel, Gijs A, Overkleeft, Herman S

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Identification and Development of Biphenyl Substituted Iminosugars as Improved Dual Glucosylceramide Synthase/Neutral Glucosylceramidase Inhibitors von Ghisaidoobe, Amar T, van den Berg, Richard J. B. H. N, Butt, Saleem S, Strijland, Anneke, Donker-Koopman, Wilma E, Scheij, Saskia, van den Nieuwendijk, Adrianus M. C. H, Koomen, Gerrit-Jan, van Loevezijn, Arnold, Leemhuis, Mark, Wennekes, Tom, van der Stelt, Mario, van der Marel, Gijsbert A, van Boeckel, Constant A. A, Aerts, Johannes M. F. G, Overkleeft, Herman S

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Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors von van den Berg, Richard J. B. H. N., van Rijssel, Erwin R., Ferraz, Maria Joao, Houben, Judith, Strijland, Anneke, Donker-Koopman, Wilma E., Wennekes, Tom, Bonger, Kimberly M., Ghisaidoobe, Amar B. T., Hoogendoorn, Sascha, van der Marel, Gijsbert A., Codée, Jeroen D. C., Overkleeft, Herman S., Aerts, Johannes M. F. G.

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An Efficient Synthesis of the Natural Tetrahydrofuran Pachastrissamine Starting from d-ribo-Phytosphingosine von van den Berg, Richard J. B. H. N, Boltje, Thomas J, Verhagen, Carlo P, Litjens, Remy E. J. N, van der Marel, Gijsbert A, Overkleeft, Herman S

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Synthesis of 6‑Hydroxysphingosine and α‑Hydroxy Ceramide Using a Cross-Metathesis Strategy von Wisse, Patrick, de Geus, Mark A. R, Cross, Gen, van den Nieuwendijk, Adrianus M. C. H, van Rooden, Eva J, van den Berg, Richard J. B. H. N, Aerts, Johannes M. F. G, van der Marel, Gijsbert A, Codée, Jeroen D. C, Overkleeft, Herman S

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A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals von Rugen, Michael D., Vernet, Mathieu M. J. L., Hantouti, Laila, Soenens, Amalia, Andriotis, Vasilios M. E., Rejzek, Martin, Brett, Paul, van den Berg, Richard J. B. H. N., Aerts, Johannes M. F. G., Overkleeft, Hermen S., Field, Robert A.

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Two-step activity-based protein profiling of diacylglycerol lipase von van Rooden, Eva J, Kreekel, Roy, Hansen, Thomas, Janssen, Antonius P A, van Esbroeck, Annelot C M, den Dulk, Hans, van den Berg, Richard J B H N, Codée, Jeroen D C, van der Stelt, Mario

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Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA von Bakker, Alexander T., Kotsogianni, Ioli, Mirenda, Liza, Straub, Verena M., Avalos, Mariana, van den Berg, Richard J. B. H. N., Florea, Bogdan I., van Wezel, Gilles P., Janssen, Antonius P. A., Martin, Nathaniel I., van der Stelt, Mario

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A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase von Lahav, Daniël, Liu, Bing, van den Berg, Richard J. B. H. N, van den Nieuwendijk, Adrianus M. C. H, Wennekes, Tom, Ghisaidoobe, Amar T, Breen, Imogen, Ferraz, Maria J, Kuo, Chi-Lin, Wu, Liang, Geurink, Paul P, Ovaa, Huib, van der Marel, Gijsbert A, van der Stelt, Mario, Boot, Rolf G, Davies, Gideon J, Aerts, Johannes M. F. G, Overkleeft, Herman S

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Synthesis and evaluation of homo-bivalent GnRHR ligands von Bonger, Kimberly M., van den Berg, Richard J.B.H.N., Heitman, Laura H., IJzerman, Ad P., Oosterom, Julia, Timmers, Cornelis M., Overkleeft, Herman S., van der Marel, Gijsbert A.

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Structure–Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors von Jiang, Ming, Huizenga, Mirjam C. W., Mohr, Florian, Amedi, Avand, Bakker, Renze, van den Berg, Richard J. B. H. N., Deng, Hui, van der Wel, Tom, van Boeckel, Constant A.A., van der Stelt, Mario

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Epi-Cyclophellitol Cyclosulfate, a Mechanism-Based Endoplasmic Reticulum α‑Glucosidase II Inhibitor, Blocks Replication of SARS-CoV‑2 and Other Coronaviruses von Thaler, Melissa, Ofman, Tim P., Kok, Ken, Heming, Jurriaan J. A., Moran, Elisha, Pickles, Isabelle, Leijs, Anouk A., van den Nieuwendijk, Adrianus M. C. H., van den Berg, Richard J. B. H. N., Ruijgrok, Gijs, Armstrong, Zachary, Salgado-Benvindo, Clarisse, Ninaber, Dennis K., Snijder, Eric J., van Boeckel, Constant A. A., Artola, Marta, Davies, Gideon J., Overkleeft, Herman S., van Hemert, Martijn J.

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Nanomolar affinity, iminosugar-based chemical probes for specific labeling of lysosomal glucocerebrosidase von Scherpenzeel, Monique van, van den Berg, Richard J.B.H.N., Donker-Koopman, Wilma E., Liskamp, Rob M.J., Aerts, Johannes M.F.G., Overkleeft, Herman S., Pieters, Roland J.

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