A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature von Kemble, Alicia M, Hornsperger, Benoit, Ruf, Iris, Richter, Hans, Benz, Jörg, Kuhn, Bernd, Heer, Dominik, Wittwer, Matthias, Engelhardt, Britta, Grether, Uwe, Collin, Ludovic

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Discovery of 3‑Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors von Liu, Yongfu, Wu, Jun, Zhou, Mingwei, Chen, Wenming, Li, Dongbo, Wang, Zhanguo, Hornsperger, Benoit, Aebi, Johannes D, Märki, Hans-Peter, Kuhn, Bernd, Wang, Lisha, Kuglstatter, Andreas, Benz, Jörg, Müller, Stephan, Hochstrasser, Remo, Ottaviani, Giorgio, Xin, Jian, Kirchner, Stephan, Mohr, Susanne, Verry, Philippe, Riboulet, William, Shen, Hong C, Mayweg, Alexander V, Amrein, Kurt, Tan, Xuefei

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Discovery of 4‑Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus... von Martin, Rainer E, Aebi, Johannes D, Hornsperger, Benoit, Krebs, Hans-Jakob, Kuhn, Bernd, Kuglstatter, Andreas, Alker, André M, Märki, Hans Peter, Müller, Stephan, Burger, Dominique, Ottaviani, Giorgio, Riboulet, William, Verry, Philippe, Tan, Xuefei, Amrein, Kurt, Mayweg, Alexander V

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HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model von Melo, Esther, Oertle, Philipp, Trepp, Carolyn, Meistermann, Hélène, Burgoyne, Thomas, Sborgi, Lorenzo, Cabrera, Alvaro Cortes, Chen, Chia-yi, Hoflack, Jean-Christophe, Kam-Thong, Tony, Schmucki, Roland, Badi, Laura, Flint, Nicholas, Ghiani, Zeynep Eren, Delobel, Fréderic, Stucki, Corinne, Gromo, Giulia, Einhaus, Alfred, Hornsperger, Benoit, Golling, Sabrina, Siebourg-Polster, Juliane, Gerber, Francoise, Bohrmann, Bernd, Futter, Clare, Dunkley, Tom, Hiller, Sebastian, Schilling, Oliver, Enzmann, Volker, Fauser, Sascha, Plodinec, Marija, Iacone, Roberto

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Development of a Highly Selective NanoBRET Probe to Assess MAGL Inhibition in Live Cells von Gazzi, Thais, Brennecke, Benjamin, Olikauskas, Valentas, Hochstrasser, Remo, Wang, Haiyan, Keen Chao, Suzan, Atz, Kenneth, Mostinski, Yelena, Topp, Andreas, Heer, Dominik, Kaufmann, Isabelle, Ritter, Martin, Gobbi, Luca, Hornsperger, Benoit, Wagner, Bjoern, Richter, Hans, O'Hara, Fionn, Wittwer, Matthias B, Jul Hansen, Dennis, Collin, Ludovic, Kuhn, Bernd, Benz, Joerg, Grether, Uwe, Nazaré, Marc

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Structure-Guided Discovery of cis-Hexahydro-pyrido-oxazinones as Reversible, Drug-like Monoacylglycerol Lipase Inhibitors von Kuhn, Bernd, Ritter, Martin, Hornsperger, Benoit, Bell, Charles, Kocer, Buelent, Rombach, Didier, Lutz, Marius D. R., Gobbi, Luca, Kuratli, Martin, Bartelmus, Christian, Bürkler, Markus, Koller, Raffael, Tosatti, Paolo, Ruf, Iris, Guerard, Melanie, Pavlovic, Anto, Stephanus, Juliane, O’Hara, Fionn, Wetzl, Dennis, Saal, Wiebke, Stihle, Martine, Roth, Doris, Hug, Melanie, Huber, Sylwia, Heer, Dominik, Kroll, Carsten, Topp, Andreas, Schneider, Manfred, Gertsch, Jürg, Glasmacher, Sandra, van der Stelt, Mario, Martella, Andrea, Wittwer, Matthias Beat, Collin, Ludovic, Benz, Jörg, Richter, Hans, Grether, Uwe

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Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold von He, Yingfang, Gobbi, Luca C., Herde, Adrienne Müller, Rombach, Didier, Ritter, Martin, Kuhn, Bernd, Wittwer, Matthias B., Heer, Dominik, Hornsperger, Benoit, Bell, Charles, O'Hara, Fionn, Benz, Jörg, Honer, Michael, Keller, Claudia, Collin, Ludovic, Richter, Hans, Schibli, Roger, Grether, Uwe, Mu, Linjing

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Abstract 2138: Creating next-generation biologics using a novel chemistry platform technology von Pattabiraman, Vijaya R., Ruiz, Matilde Arévalo, Boehringer, Régis, Hornsperger, Benoit, Meoded, Roy, Tam, Robert C., Kreft, Bertolt

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4,4A,5,7,8,8A-HEXAPYRIDO[4,3-B][1,4]OXAZIN-3-ONE COMPOUNDS AS MAGL INHIBITORS von HORNSPERGER, Benoit, KROLL, Carsten, O'HARA, Fionn, RICHTER, Hans, GRETHER, Uwe, LUTZ, Marius Daniel Rinaldo, KUHN, Bernd

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4,4A,5,7,8,8A-HEXAPYRIDO[4,3-B][1,4]OXAZIN-3-ONE COMPOUNDS AS MAGL INHIBITORS von HORNSPERGER, Benoit, KROLL, Carsten, O'HARA, Fionn, RICHTER, Hans, GRETHER, Uwe, LUTZ, Marius Daniel Rinaldo, KUHN, Bernd

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NEW HETEROCYCLIC COMPOUNDS von HORNSPERGER, Benoit, KROLL, Carsten, RICHTER, Hans, KOSAR, Miroslav, GRETHER, Uwe, O`HARA, Fionn, REGGIANI, Flore, BIEDERMANN, Maurice, KUHN, Bernd

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NEW HETEROCYCLIC COMPOUNDS von HORNSPERGER, Benoit, KROLL, Carsten, RICHTER, Hans, KOSAR, Miroslav, GRETHER, Uwe, O`HARA, Fionn, REGGIANI, Flore, BIEDERMANN, Maurice, KUHN, Bernd

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BEZOXAZINE DERIVATIVES USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS von HORNSPERGER, Benoit, RICHTER, Hans, BENZ, Joerg, GRETHER, Uwe, KOCER, Buelent, BELL, Charles, KUHN, Bernd, TSUCHIYA, Satoshi

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MODIFIED IL-18 POLYPEPTIDES von MOOSMANN, Philipp, HORNSPERGER, Benoit, ONGARO, Tiziano, MEODED, Roy, KREFT, Bertolt, PATTABIRAMAN, Vijaya Raghavan, BOEHRINGER, Régis, DELON, Camille, MARTIN, Kea, GOEPFERT, Arnaud, CARRALOT, Jean-Philippe, CHI, Andrew

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New heterocyclic compounds von Kroll, Carsten, Richter, Hans, Grether, Uwe, Groebke Zbinden, Katrin, Rombach, Didier, Kuhn, Bernd, Lutz, Marius Daniel Rinaldo, Hornsperger, Benoit, O`hara, Fionn

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MODIFIED IL-18 POLYPEPTIDES von MOOSMANN, Philipp, HORNSPERGER, Benoit, ONGARO, Tiziano, MEODED, Roy, KREFT, Bertolt, PATTABIRAMAN, Vijaya Raghavan, BOEHRINGER, Régis, DELON, Camille, MARTIN, Kea, GOEPFERT, Arnaud, CARRALOT, Jean-Philippe, CHI, Andrew

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HETEROCYCLIC COMPOUNDS USEFUL AS MAGL INHIBITORS von HORNSPERGER, Benoit, KROLL, Carsten, O'HARA, Fionn, RICHTER, Hans, SCHMID, Philipp, BENZ, Joerg, GRETHER, Uwe, RITTER, Martin, MARTIN, Rainer E, KUHN, Bernd

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HETEROCYCLIC COMPOUNDS USEFUL AS MAGL INHIBITORS von HORNSPERGER, Benoit, KROLL, Carsten, O'HARA, Fionn, RICHTER, Hans, SCHMID, Philipp, BENZ, Joerg, GRETHER, Uwe, RITTER, Martin, MARTIN, Rainer E, KUHN, Bernd

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Heterocyclic compounds von Martin, Rainer E, Kroll, Carsten, O'Hara, Fionn, Richter, Hans, Ritter, Martin, Grether, Uwe, Kuhn, Bernd, Benz, Joerg, Hornsperger, Benoit, Puellmann, Bernd

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4,4A,5,7,8,8A-HEXAPYRIDO[4,3-B][1,4]OXAZIN-3-ONE COMPOUNDS AS MAGL INHIBITORS von HORNSPERGER, Benoit, KROLL, Carsten, O'HARA, Fionn, RICHTER, Hans, GRETHER, Uwe, LUTZ, Marius Daniel Rinaldo, KUHN, Bernd

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