Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity von Sivick, Kelsey E., Desbien, Anthony L., Glickman, Laura Hix, Reiner, Gabrielle L., Corrales, Leticia, Surh, Natalie H., Hudson, Thomas E., Vu, Uyen T., Francica, Brian J., Banda, Tamara, Katibah, George E., Kanne, David B., Leong, Justin J., Metchette, Ken, Bruml, Jacob R., Ndubaku, Chudi O., McKenna, Jeffrey M., Feng, Yan, Zheng, Lianxing, Bender, Steven L., Cho, Charles Y., Leong, Meredith L., van Elsas, Andrea, Dubensky, Thomas W., McWhirter, Sarah M.

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An orally available small-molecule inhibitor of c-met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms von ZOU, Helen Y, QIUHUA LI, NAMBU, Mitchell D, LOS, Gerrit, BENDER, Steven L, MROCZKOWSKI, Barbara, CHRISTENSEN, James G, LEE, Joseph H, ARANGO, Maria E, MCDONNELL, Scott R, YAMAZAKI, Shinji, KOUDRIAKOVA, Tatiana B, ALTON, Gordon, CUI, Jingrong J, KUNG, Pei-Pei

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Molecular Recognition of Protein−Ligand Complexes:  Applications to Drug Design von Babine, Robert E, Bender, Steven L

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Sensitivity of selected human tumor models to PF-04217903, a novel selective c-Met kinase inhibitor von Zou, Helen Y, Li, Qiuhua, Lee, Joseph H, Arango, Maria E, Burgess, Kristina, Qiu, Ming, Engstrom, Lars D, Yamazaki, Shinji, Parker, Max, Timofeevski, Sergei, Cui, Jingrong Jean, McTigue, Michele, Los, Gerrit, Bender, Steven L, Smeal, Tod, Christensen, James G

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Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity von Sivick, Kelsey E., Desbien, Anthony L., Glickman, Laura Hix, Reiner, Gabrielle L., Corrales, Leticia, Surh, Natalie H., Hudson, Thomas E., Vu, Uyen T., Francica, Brian J., Banda, Tamara, Katibah, George E., Kanne, David B., Leong, Justin J., Metchette, Ken, Bruml, Jacob R., Ndubaku, Chudi O., McKenna, Jeffrey M., Feng, Yan, Zheng, Lianxing, Bender, Steven L., Cho, Charles Y., Leong, Meredith L., van Elsas, Andrea, Dubensky, Thomas W., McWhirter, Sarah M.

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Abstract 1445: STING activation in the tumor microenvironment with a synthetic human STING-activating cyclic dinucleotide leads to potent anti-tumor immunity von Glickman, Laura Hix, Kanne, David B., Kasibhatla, Shailaja, Li, Jie, Pferdekamper, AnneMarie Culazzo, Gauthier, Kelsey Sivick, Deng, Weiwen, Desbien, Anthony L., Katibah, George E., Leong, Justin J., Sung, Leonard, Metchette, Ken, Ndubaku, Chudi, Zheng, Lianxing, Cho, Charles, Feng, Yan, McKenna, Jeffrey M., Tallarico, John A., Bender, Steven L., Dubensky, Thomas W., McWhirter, Sarah M.

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Abstract SY39-02: Direct activation of STING in the tumor microenvironment leads to potent and systemic tumor regression and immunity von Glickman, Laura Hix, Corrales, Leticia, Kanne, David B., Kasibhatla, Shailaja, Li, Jie, Pferdekamper, Anne Marie Culazzo, Gauthier, Kelsey Sivick, Katibah, George E., Leong, Justin J., Sung, Leonard, Metchette, Ken, Deng, Weiwen, Desbien, Anthony L., Ndubaku, Chudi, Zheng, Lianxing, Cho, Charles, Feng, Yan, McKenna, Jeffery M., Tallarico, John A., Bender, Steven L., McWhirter, Sarah M., Gajewski, Thomas F., Dubensky, Thomas W.

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The total synthesis of the polyether antibiotic X-206 von Evans, David A, Bender, Steven L, Morris, Joel

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Dual Functional Monoclonal Antibody PF-04605412 Targets Integrin α5β1 and Elicits Potent Antibody-Dependent Cellular Cytotoxicity von Li, Gang, Zhang, Lianglin, Chen, Enhong, Wang, Jianying, Jiang, Xin, Chen, Jeffrey H., Wickman, Grant, Amundson, Karin, Bergqvist, Simon, Zobel, James, Buckman, Dana, Baxi, Sangita M., Bender, Steven L., Casperson, Gerald F., Hu-Lowe, Dana D.

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Biomimetic synthesis of enantiomerically pure D-myo-inositol derivatives von Bender, Steven L, Budhu, Richard J

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Dehydroquinate synthase: the use of substrate analogs to probe the early steps of the catalyzed reaction von Bender, Steven L, Widlanski, Theodore, Knowles, Jeremy R

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Synthesis and Biological Activity of Novel Nonsteroidal Progesterone Receptor Antagonists Based on Cyclocymopol Monomethyl Ether von Hamann, Lawrence G, Farmer, Luc J, Johnson, Michael G, Bender, Steven L, Mais, Dale E, Wang, Ming-Wei, Crombie, Diane, Goldman, Mark E, Jones, Todd K

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Dehydroquinate synthase: the use of substrate analogs to probe the late steps of the catalyzed reaction von Widlanski, Theodore, Bender, Steven L, Knowles, Jeremy R

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Dehydroquinate synthase: the role of divalent metal cations and of nicotinamide adenine dinucleotide in catalysis von Bender, Steven L, Mehdi, Shujaath, Knowles, Jeremy R

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Abstract 1202: Tumor cell intrinsic STING signaling demonstrates minimal contribution to the anti-tumor response elicited by the STING agonist ADU-S100 (MIW815) von Corrales, Leticia, Desbien, Antony L., Gauthier, Kelsey E. Sivick, Deng, Weiwen, Schroeder, Tamara, Reiner, Gabrielle L., Surh, Natalie, Francica, Brian, Metchette, Ken, Ndubaku, Chudi O., McKenna, Jeffrey M., Feng, Yan, Zheng, Lianxing, Bender, Steven L., Cho, Charles Y., Elsas, Andrea van, Leong, Meredith L., McWhirter, Sarah M.

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Abstract 631: Intratumoral activation of STING with a synthetic cyclic dinucleotide elicits antitumor CD8 T-cell immunity that effectively combines with checkpoint inhibitors von Desbien, Anthony L., Gauthier, Kelsey Sivick, Corrales, Leticia, Reiner, Gabrielle, Glickman, Laura Hix, Katibah, George, Hudson, Thomas E., Vu, Uyen, Surh, Natalie H., Francica, Brian, Deng, Weiwen, Kanne, David B., Leong, Justin J., Ndubaku, Chudi, Metchette, Ken, McKenna, Jeffery M., Bender, Steven L., Leong, Meredith L., Dubensky, Thomas W., Elsas, Andrea van, McWhirter, Sarah M.

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Stereochemical course of the cryptic elimination and cyclization steps in the reaction catalyzed by dehydroquinate synthase von Widlanski, Theodore S, Bender, Steven L, Knowles, Jeremy R

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Abstract PR09: ADU-S100 (MIW815) synergizes with checkpoint blockade to elicit an antitumor CD8+ T-cell response to control distal tumors von Deng, Weiwen, Desbien, Anthony L., Gauthier, Kelsey Sivick, Reiner, Gabrielle, Corrales, Leticia, Schroeder, Tamara, Glickman, Laura Hix, Surh, Natalie H., Francica, Brian, Leong, Justin J., Metchette, Ken, Zheng, Lianxing, Cho, Charles, Feng, Yan, McKenna, Jeffery M., Bender, Steven L., Ndubaku, Chudi, Leong, Meredith L., van Elsas, Andrea, McWhirter, Sarah M.

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Indolizines. 3. Oxidation products of indolizinols: radicals, ions, and oxidized dimers von Wadsworth, Donald H, Weidner, Charles H, Bender, Steven L, Nuttall, Robert H, Luss, Henry R

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RNA TARGETING COMPOUNDS AND USES THEREOF von BENDER, Steven L

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