Neuronal nicotinic receptors as novel targets for inflammation and neuroprotection: mechanistic considerations and clinical relevance von Bencherif, Merouane

Volltext

Alpha7 nicotinic receptors as novel therapeutic targets for inflammation-based diseases von Bencherif, Merouane, Lippiello, Patrick M, Lucas, Rudolf, Marrero, Mario B

Volltext

An α7 Nicotinic Acetylcholine Receptor-Selective Agonist Reduces Weight Gain and Metabolic Changes in a Mouse Model of Diabetes von Marrero, Mario B., Lucas, Rudolf, Salet, Christina, Hauser, Terry A., Mazurov, Anatoly, Lippiello, Patrick M., Bencherif, Merouane

Volltext

Structural differences determine the relative selectivity of nicotinic compounds for native α4β2-, α6β2-, α3β4- and α7-nicotine acetylcholine receptors von Grady, Sharon R., Drenan, Ryan M., Breining, Scott R., Yohannes, Daniel, Wageman, Charles R., Fedorov, Nikolai B., McKinney, Sheri, Whiteaker, Paul, Bencherif, Merouane, Lester, Henry A., Marks, Michael J.

Volltext

Application of Alpha7 Nicotinic Acetylcholine Receptor Agonists in Inflammatory Diseases: An Overview von Marrero, Mario B, Bencherif, Merouane, Lippiello, Patrick M, Lucas, Rudolf

Volltext

α7 Nicotinic receptor agonist reactivates neurogenesis in adult brain von Narla, Sridhar, Klejbor, Ilona, Birkaya, Barbara, Lee, Yu-Wei, Morys, Janusz, Stachowiak, Ewa K., Terranova, Christopher, Bencherif, Merouane, Stachowiak, Michal K.

Volltext

TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors von Wall, Teagan R, Henderson, Brandon J, Voren, George, Wageman, Charles R, Deshpande, Purnima, Cohen, Bruce N, Grady, Sharon R, Marks, Michael J, Yohannes, Daniel, Kenny, Paul J, Bencherif, Merouane, Lester, Henry A

Volltext

Differential Pharmacologies of Mecamylamine Enantiomers: Positive Allosteric Modulation and Noncompetitive Inhibition von Fedorov, Nikolai B, Benson, Lisa C, Graef, John, Lippiello, Patrick M, Bencherif, Merouane

Volltext

Activation of Developmental Nuclear Fibroblast Growth Factor Receptor 1 Signaling and Neurogenesis in Adult Brain by α7 Nicotinic Receptor Agonist von Narla, Sridhar T., Klejbor, Ilona, Birkaya, Barbara, Lee, Yu-Wei, Morys, Janusz, Stachowiak, Ewa K., Prokop, Dorota, Bencherif, Merouane, Stachowiak, Michal K.

Volltext

Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: Central role for JAK2 activation of STAT3 and NF-κB von Marrero, Mario B, Bencherif, Merouane

Volltext

Janus Kinase 2, an Early Target of α7 Nicotinic Acetylcholine Receptor-mediated Neuroprotection against Aβ-(1–42) Amyloid von Shaw, Seán, Bencherif, Merouane, Marrero, Mario B.

Volltext

In Vivo Activation of Midbrain Dopamine Neurons via Sensitized, High-Affinity α6 ∗ Nicotinic Acetylcholine Receptors von Drenan, Ryan M., Grady, Sharon R., Whiteaker, Paul, McClure-Begley, Tristan, McKinney, Sheri, Miwa, Julie M., Bupp, Sujata, Heintz, Nathaniel, McIntosh, J. Michael, Bencherif, Merouane, Marks, Michael J., Lester, Henry A.

Volltext

The Activation and Inhibition of Human Nicotinic Acetylcholine Receptor by RJR‐2403 Indicate a Selectivity for the α4β2 Receptor Subtype von Papke, Roger L., Webster, J. Christopher, Lippiello, Patrick M., Bencherif, Merouane, Francis, Michael M.

Volltext

Comparative Study on the Use of Docking and Bayesian Categorization To Predict Ligand Binding to Nicotinic Acetylcholine Receptors (nAChRs) Subtypes von Kombo, David C, Bencherif, Merouane

Volltext

Nicotinic receptor agonists reduce L-DOPA-induced dyskinesias in a monkey model of Parkinson's disease von Zhang, Danhui, Mallela, Archana, Sohn, David, Carroll, F Ivy, Bencherif, Merouane, Letchworth, Sharon, Quik, Maryka

Volltext

TC-2559: A novel orally active ligand selective at neuronal acetylcholine receptors von Bencherif, Merouane, Bane, Andrew J, Miller, Craig H, Dull, Gary M, Gatto, Gregory J

Volltext

Effects of incorporation of α5 subunits into α4β2 nicotinic acetylcholine receptors on pharmacological functions of nicotinic ligands von Zhang, Jenny, Bencherif, Merouane, Hauser, Terry

Volltext

Alpha7 neuronal nicotinic receptors: The missing link to understanding Alzheimer’s etiopathology? von Bencherif, Merouane, Lippiello, Patrick M

Volltext

Computational studies of novel carbonyl-containing diazabicyclic ligands interacting with I-4I22 nicotinic acetylcholine receptor (nAChR) reveal alternative binding modes von Kombo, David, Mazurov, Anatoly, Strachan, Jon-Paul, Bencherif, Merouane

Volltext

QM-polarized ligand docking accurately predicts the trend in binding affinity of a series of arylmethylene quinuclidine-like derivatives at the I-4I22 and I-3I24 nicotinic acetylch... von Kombo, David, Grinevich, Vladimir, Hauser, Terry, Sidach, Serguei, Bencherif, Merouane

Volltext