protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9 von Nakamaru, Yuji, Vuppusetty, Chaitanya, Wada, Hiroo, Milne, Jill C, Ito, Misako, Rossios, Christos, Elliot, Mark, Hogg, James, Kharitonov, Sergei, Goto, Hajime, Bemis, Jean E, Elliott, Peter, Barnes, Peter J, Ito, Kazuhiro

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Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes von Jin, Lei, Wei, Wentao, Jiang, Yaobin, Peng, Hao, Cai, Jianhua, Mao, Chen, Dai, Han, Choy, Wendy, Bemis, Jean E., Jirousek, Michael R., Milne, Jill C., Westphal, Christoph H., Perni, Robert B.

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Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3 von Jin, Lei, Galonek, Heidi, Israelian, Kristine, Choy, Wendy, Morrison, Michael, Xia, Yu, Wang, Xiaohong, Xu, Yihua, Yang, Yuecheng, Smith, Jesse J., Hoffmann, Ethan, Carney, David P., Perni, Robert B., Jirousek, Michael R., Bemis, Jean E., Milne, Jill C., Sinclair, David A., Westphal, Christoph H.

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Discovery of oxazolo[4,5- b]pyridines and related heterocyclic analogs as novel SIRT1 activators von Bemis, Jean E., Vu, Chi B., Xie, Roger, Nunes, Joseph J., Ng, Pui Yee, Disch, Jeremy S., Milne, Jill C., Carney, David P., Lynch, Amy V., Jin, Lei, Smith, Jesse J., Lavu, Siva, Iffland, Andre, Jirousek, Michael R., Perni, Robert B.

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Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes von Choy, Wendy, Sinclair, David A, Lambert, Philip D, Gagne, David J, Lynch, Amy V, Milne, Jill C, Bemis, Jean E, Boss, Olivier, Perni, Robert B, Schenk, Simon, Carney, David P, Yang, Hongying, Ng, Pui Yee, Iffland, Andre, Smith, Jesse J, Elliott, Peter J, Vu, Chi B, Xie, Roger, Galonek, Heidi, Israelian, Kristine, Lavu, Siva, Medvedik, Oliver, Olefsky, Jerrold M, Disch, Jeremy S, Nunes, Joseph J, Jirousek, Michael R, Westphal, Christoph H, Jin, Lei

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Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid von Vu, Chi B, Bemis, Jean E, Benson, Ericka, Bista, Pradeep, Carney, David, Fahrner, Richard, Lee, Diana, Liu, Feng, Lonkar, Pallavi, Milne, Jill C, Nichols, Andrew J, Picarella, Dominic, Shoelson, Adam, Smith, Jesse, Ting, Amal, Wensley, Allison, Yeager, Maisy, Zimmer, Michael, Jirousek, Michael R

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Discovery of Imidazo[1,2-b]thiazole Derivatives as Novel SIRT1 Activators von Vu, Chi B, Bemis, Jean E, Disch, Jeremy S, Ng, Pui Yee, Nunes, Joseph J, Milne, Jill C, Carney, David P, Lynch, Amy V, Smith, Jesse J, Lavu, Siva, Lambert, Philip D, Gagne, David J, Jirousek, Michael R, Schenk, Simon, Olefsky, Jerrold M, Perni, Robert B

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Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck:  Synthesis, SAR, and in Vivo Anti-Inflammatory Activity von DiMauro, Erin F, Newcomb, John, Nunes, Joseph J, Bemis, Jean E, Boucher, Christina, Buchanan, John L, Buckner, William H, Cee, Victor J, Chai, Lilly, Deak, Holly L, Epstein, Linda F, Faust, Ted, Gallant, Paul, Geuns-Meyer, Stephanie D, Gore, Anu, Gu, Yan, Henkle, Brad, Hodous, Brian L, Hsieh, Faye, Huang, Xin, Kim, Joseph L, Lee, Josie H, Martin, Matthew W, Masse, Craig E, McGowan, David C, Metz, Daniela, Mohn, Deanna, Morgenstern, Kurt A, Oliveira-dos-Santos, Antonio, Patel, Vinod F, Powers, David, Rose, Paul E, Schneider, Stephen, Tomlinson, Susan A, Tudor, Yan-Yan, Turci, Susan M, Welcher, Andrew A, White, Ryan D, Zhao, Huilin, Zhu, Li, Zhu, Xiaotian

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Discovery of 4-amino-5,6-biaryl-furo[2,3- d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR von DiMauro, Erin F., Newcomb, John, Nunes, Joseph J., Bemis, Jean E., Boucher, Christina, Buchanan, John L., Buckner, William H., Cheng, Alan, Faust, Theodore, Hsieh, Faye, Huang, Xin, Lee, Josie H., Marshall, Teresa L., Martin, Matthew W., McGowan, David C., Schneider, Stephen, Turci, Susan M., White, Ryan D., Zhu, Xiaotian

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Discovery of novel 2,3-diarylfuro[2,3- b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties von Martin, Matthew W., Newcomb, John, Nunes, Joseph J., Bemis, Jean E., McGowan, David C., White, Ryan D., Buchanan, John L., DiMauro, Erin F., Boucher, Christina, Faust, Theodore, Hsieh, Faye, Huang, Xin, Lee, Josie H., Schneider, Stephen, Turci, Susan M., Zhu, Xiaotian

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Structure-Guided Design of Aminopyrimidine Amides as Potent, Selective Inhibitors of Lymphocyte Specific Kinase: Synthesis, Structure–Activity Relationships, and Inhibition of in V... von DiMauro, Erin F, Newcomb, John, Nunes, Joseph J, Bemis, Jean E, Boucher, Christina, Chai, Lilly, Chaffee, Stuart C, Deak, Holly L, Epstein, Linda F, Faust, Ted, Gallant, Paul, Gore, Anu, Gu, Yan, Henkle, Brad, Hsieh, Faye, Huang, Xin, Kim, Joseph L, Lee, Josie H, Martin, Matthew W, McGowan, David C, Metz, Daniela, Mohn, Deanna, Morgenstern, Kurt A, Oliveira-dos-Santos, Antonio, Patel, Vinod F, Powers, David, Rose, Paul E, Schneider, Stephen, Tomlinson, Susan A, Tudor, Yan-Yan, Turci, Susan M, Welcher, Andrew A, Zhao, Huilin, Zhu, Li, Zhu, Xiaotian

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conjugados de ácido graxo niacina e seus usos von Chi B. Vu, Michael R. Jirousek, Jill C. Milne, Jean E. Bemis

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Crystal Structures of Human SIRT[subscript 3] Displaying Substrate-induced Conformational Changes von Jin, Lei, Wei, Wentao, Jiang, Yaobin, Peng, Hao, Cai, Jianhua, Mao, Chen, Dai, Han, Choy, Wendy, Bemis, Jean E., Jirousek, Michael R., Milne, Jill C., Westphal, Christoph H., Perni, Robert B.

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salicilatos acetilados de ácidos graxos e seus usos von Jesse J. Smith, Michael R. Jirousek, Jill C. Milne, Jean E. Bemis

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Salicilatos acetilados de ácidos grasos y sus usos von Milne, C. Jill, Jirousek, R. Michael, Bemis, E. Jean, Smith, J. Jesse

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Erratum to “Discovery of novel 2,3-diarylfuro[2,3- b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties” [Bioorg. Med. Chem.... von Martin, Matthew W., Newcomb, John, Nunes, Joseph J., Bemis, Jean E., McGowan, David C., White, Ryan D., Buchanan, John L., DiMauro, Erin F., Boucher, Christina, Faust, Theodore, Hsieh, Faye, Huang, Xin, Lee, Josie H., Schneider, Stephen, Turci, Susan M., Zhu, Xiaotian

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Conjugados de ácido graso y niacina y sus usos von JIROUSEK, Michael R, BEMIS, Jean E, MILNE, Jill C, VU, Chi B

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Erratum to “Discovery of 4-amino-5,6-biaryl-furo[2,3- d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR” [Bioorg. Me... von DiMauro, Erin F., Newcomb, John, Nunes, Joseph J., Bemis, Jean E., Boucher, Christina, Buchanan, John L., Buckner, William H., Cheng, Alan, Faust, Theodore, Hsieh, Faye, Huang, Xin, Lee, Josie H., Marshall, Teresa L., Martin, Matthew W., McGowan, David C., Schneider, Stephen, Turci, Susan M., White, Ryan D., Zhu, Xiaotian

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SALICILATOS ACETILADOS CON ACIDOS GRASOS Y SUS USOS von SMITH, JESSE J, BEMIS, JEAN E, MILNE, JILL C, JIROUSEK, MICHAEL R

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Derivados de fumarato de acido graxo e seus usos von CHI B. VU, JILL C. MILNE, MICHAEL R. JIROUSEK, JEAN E. BEMIS, JESSE J. SMITH

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