Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases von Prisic, Sladjana, Dankwa, Selasi, Schwartz, Daniel, Chou, Michael F, Locasale, Jason W, Kang, Choong-Min, Bemis, Guy, Church, George M, Steen, Hanno, Husson, Robert N

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The Properties of Known Drugs. 1. Molecular Frameworks von Bemis, Guy W, Murcko, Mark A

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BREED:  Generating Novel Inhibitors through Hybridization of Known Ligands. Application to CDK2, P38, and HIV Protease von Pierce, Albert C, Rao, Govinda, Bemis, Guy W

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Structure-Guided Design of Potent and Selective Pyrimidylpyrrole Inhibitors of Extracellular Signal-Regulated Kinase (ERK) Using Conformational Control von Aronov, Alex M, Tang, Qing, Martinez-Botella, Gabriel, Bemis, Guy W, Cao, Jingrong, Chen, Guanjing, Ewing, Nigel P, Ford, Pamella J, Germann, Ursula A, Green, Jeremy, Hale, Michael R, Jacobs, Marc, Janetka, James W, Maltais, Francois, Markland, William, Namchuk, Mark N, Nanthakumar, Suganthini, Poondru, Srinivasu, Straub, Judy, ter Haar, Ernst, Xie, Xiaoling

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Properties of Known Drugs. 2. Side Chains von Bemis, Guy W, Murcko, Mark A

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Structure-based design of 3-aryl-6-amino-triazolo[4,3-b]pyridazine inhibitors of Pim-1 kinase von Grey, Ron, Pierce, Albert C., Bemis, Guy W., Jacobs, Marc D., Moody, Cameron Stuver, Jajoo, Rahul, Mohal, Narinder, Green, Jeremy

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Designing Libraries with CNS Activity von Ajay, Bemis, Guy W, Murcko, Mark A

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Flipped Out:  Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors von Aronov, Alex M, Baker, Christopher, Bemis, Guy W, Cao, Jingrong, Chen, Guanjing, Ford, Pamella J, Germann, Ursula A, Green, Jeremy, Hale, Michael R, Jacobs, Marc, Janetka, James W, Maltais, Francois, Martinez-Botella, Gabriel, Namchuk, Mark N, Straub, Judy, Tang, Qing, Xie, Xiaoling

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Kinase inhibitors and the case for CH…O hydrogen bonds in protein–ligand binding von Pierce, Albert C., Sandretto, Kathryn L., Bemis, Guy W.

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The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor von Duffy, John P, Harrington, Edmund M, Salituro, Francesco G, Cochran, John E, Green, Jeremy, Gao, Huai, Bemis, Guy W, Evindar, Ghotas, Galullo, Vincent P, Ford, Pamella J, Germann, Ursula A, Wilson, Keith P, Bellon, Steven F, Chen, Guanging, Taslimi, Paul, Jones, Peter, Huang, Cassey, Pazhanisamy, S, Wang, Yow-Ming, Murcko, Mark A, Su, Michael S.S

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A minimalist approach to fragment-based ligand design using common rings and linkers: Application to kinase inhibitors von Aronov, Alex M., Bemis, Guy W.

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CORES:  An Automated Method for Generating Three-Dimensional Models of Protein/Ligand Complexes von Hare, Brian J, Walters, W. Patrick, Caron, Paul R, Bemis, Guy W

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Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions von Wang, Tiansheng, Bemis, Guy, Hanzelka, Brian, Zuccola, Harmon, Wynn, Michael, Moody, Cameron Stuver, Green, Jeremy, Locher, Christopher, Liu, Aixiang, Gao, Hongwu, Xu, Yuzhou, Wang, Shaohui, Wang, Jie, Bennani, Youssef L, Thomson, John A, Müh, Ute

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Kinase inhibitors and the case for CH...O hydrogen bonds in protein-ligand binding von Pierce, Albert C., Sandretto, Kathryn L., Bemis, Guy W.

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Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors von Cao, Jingrong, Gao, Huai, Bemis, Guy, Salituro, Francesco, Ledeboer, Mark, Harrington, Edmund, Wilke, Susanne, Taslimi, Paul, Pazhanisamy, S., Xie, Xiaoling, Jacobs, Marc, Green, Jeremy

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The SHAPES strategy: an NMR-based approach for lead generation in drug discovery von Fejzo, Jasna, Lepre, Christopher A, Peng, Jeffrey W, Bemis, Guy W, Ajay, Murcko, Mark A, Moore, Jonathan M

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Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK) von FARMER, Luc J, BEMIS, Guy, TER HAAR, Ernst, JIAN WANG, ZHAVERI, Darshana, SALITURO, Francesco G, BRITT, Shawn D, COCHRAN, John, CONNORS, Martin, HARRINGTON, Edmund M, HOOCK, Thomas, MARKLAND, William, NANTHAKUMAR, Suganthini, TASLIMI, Paul

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4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: Potent and selective p70S6 kinase inhibitors von Bandarage, Upul, Hare, Brian, Parsons, Jonathan, Pham, Ly, Marhefka, Craig, Bemis, Guy, Tang, Qing, Moody, Cameron Stuver, Rodems, Steve, Shah, Sundeep, Adams, Chris, Bravo, Jose, Charonnet, Emmanuelle, Savic, Vladimir, Come, Jon H., Green, Jeremy

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A molecular dynamics study of the stability of chymotrypsin acyl enzymes von Bemis, Guy W, Carlson-Golab, Gail, Katzenellenbogen, John A

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ARYL SULFONAMIDE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS von FULLER, Nathan Oliver, BOSANAC, Todd, BEMIS, Guy, HUGHES, Robert Owen

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