In vivo manipulation of human gut Bacteroides fitness by abiotic oligosaccharides von Wesener, Darryl A, Beller, Zachary W, Hill, Megan F, Yuan, Han, Belanger, David B, Frankfater, Cheryl, Terrapon, Nicolas, Henrissat, Bernard, Rodionov, Dmitry A, Leyn, Semen A, Osterman, Andrei, van Hylckama Vlieg, Johan E T, Gordon, Jeffrey I

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Machine Learning ADME Models in Practice: Four Guidelines from a Successful Lead Optimization Case Study von Rich, Alexander S., Chan, Yvonne H., Birnbaum, Benjamin, Haider, Kamran, Haimson, Joshua, Hale, Michael, Han, Yongxin, Hickman, William, Hoeflich, Klaus P., Ortwine, Daniel, Özen, Ayşegül, Belanger, David B.

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Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway von Karki, Rajeshri G, Powers, James, Mainolfi, Nello, Anderson, Karen, Belanger, David B, Liu, Donglei, Ji, Nan, Jendza, Keith, Gelin, Christine F, Mac Sweeney, Aengus, Solovay, Catherine, Delgado, Omar, Crowley, Maura, Liao, Sha-Mei, Argikar, Upendra A, Flohr, Stefanie, La Bonte, Laura R, Lorthiois, Edwige L, Vulpetti, Anna, Brown, Ann, Long, Debby, Prentiss, Melissa, Gradoux, Nathalie, de Erkenez, Andrea, Cumin, Frederic, Adams, Christopher, Jaffee, Bruce, Mogi, Muneto

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Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core von Yu, Tao, Tagat, Jayaram R, Kerekes, Angela D, Doll, Ronald J, Zhang, Yonglian, Xiao, Yushi, Esposite, Sara, Belanger, David B, Curran, Patrick J, Mandal, Amit K, Siddiqui, M. Arshad, Shih, Neng-Yang, Basso, Andrea D, Liu, Ming, Gray, Kimberly, Tevar, Seema, Jones, Jennifer, Lee, Suining, Liang, Lianzhu, Ponery, Samad, Smith, Elizabeth B, Hruza, Alan, Voigt, Johannes, Ramanathan, Lata, Prosise, Winifred, Hu, Mengwei

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The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a... von Ehara, Takeru, Adams, Christopher M, Bevan, Doug, Ji, Nan, Meredith, Erik L, Belanger, David B, Powers, James, Kato, Mitsunori, Solovay, Catherine, Liu, Donglei, Capparelli, Michael, Bolduc, Philippe, Grob, Jonathan E, Daniels, Matthew H, Ferrara, Luciana, Yang, Louis, Li, Byron, Towler, Christopher S, Stacy, Rebecca C, Prasanna, Ganesh, Mogi, Muneto

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Discovery of a highly potent orally bioavailable imidazo-[1, 2-a]pyrazine Aurora inhibitor von Yu, Tao, Zhang, Yonglian, Kerekes, Angela D., Tagat, Jayaram R., Doll, Ronald J., Xiao, Yushi, Esposite, Sara, Hruza, Alan, Belanger, David B., Voss, Matthew, Rainka, Matthew P., Basso, Andrea, Liu, Ming, Liang, Lianzhu, Sui, Ning, Prelusky, Daniel, Rindgen, Diane, Zhang, Likang

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Substrate control of stereoselection in the rhodium(I) catalyzed intramolecular [4 + 2] cycloaddition reaction von O'Mahony, Donogh J R, Belanger, David B, Livinghouse, Tom

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Discovery of imidazo[1,2- a]pyrazine-based Aurora kinase inhibitors von Belanger, David B., Curran, Patrick J., Hruza, Alan, Voigt, Johannes, Meng, Zhaoyang, Mandal, Amit K., Siddiqui, M. Arshad, Basso, Andrea D., Gray, Kimberly

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Discovery of novel imidazo[1,2- a]pyrazin-8-amines as Brk/PTK6 inhibitors von Zeng, Hongbo, Belanger, David B., Curran, Patrick J., Shipps, Gerald W., Miao, Hua, Bracken, Jack B., Arshad Siddiqui, M., Malkowski, Michael, Wang, Yan

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Synthesis and SAR studies of imidazo-[1,2-a]-pyrazine Aurora kinase inhibitors with improved off-target kinase selectivity von Voss, Matthew E., Rainka, Matthew P., Fleming, Mike, Peterson, Lisa H., Belanger, David B., Siddiqui, M. Arshad, Hruza, Alan, Voigt, Johannes, Gray, Kimberly, Basso, Andrea D.

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Bioisosteric approach to the discovery of imidazo[1,2-a]pyrazines as potent Aurora kinase inhibitors von Meng, Zhaoyang, Kulkarni, Bheemashankar A., Kerekes, Angela D., Mandal, Amit K., Esposite, Sara J., Belanger, David B., Reddy, Panduranga Adulla, Basso, Andrea D., Tevar, Seema, Gray, Kimberly, Jones, Jennifer, Smith, Elizabeth B., Doll, Ronald J., Siddiqui, M. Arshad

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Discovery of orally bioavailable imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors von Belanger, David B., Williams, Michael J., Curran, Patrick J., Mandal, Amit K., Meng, Zhaoyang, Rainka, Matthew P., Yu, Tao, Shih, Neng-Yang, Siddiqui, M. Arshad, Liu, Ming, Tevar, Seema, Lee, Suining, Liang, Lianzhu, Gray, Kimberly, Yaremko, Bohdan, Jones, Jennifer, Smith, Elizabeth B., Prelusky, Dan B., Basso, Andrea D.

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The discovery of novel tartrate-based TNF-α converting enzyme (TACE) inhibitors von Rosner, Kristin E., Guo, Zhuyan, Orth, Peter, Shipps, Gerald W., Belanger, David B., Chan, Tin Yau, Curran, Patrick J., Dai, Chaoyang, Deng, Yongqi, Girijavallabhan, Vinay M., Hong, Liwu, Lavey, Brian J., Lee, Joe F., Li, Dansu, Liu, Zhidan, Popovici-Muller, Janeta, Ting, Pauline C., Vaccaro, Henry, Wang, Li, Wang, Tong, Yu, Wensheng, Zhou, Guowei, Niu, Xiaoda, Sun, Jing, Kozlowski, Joseph A., Lundell, Daniel J., Madison, Vincent, McKittrick, Brian, Piwinski, John J., Shih, Neng -Yang, Arshad Siddiqui, M., Strickland, Corey O.

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Thermal promotion of the cobalt catalyzed intramolecular Pauson-Khand reaction — An alternative experimental protocol for cyclopentenone synthesis von Belanger, David B., O'Mahony, Donogh J.R., Livinghouse, Tom

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Structure and activity relationships of tartrate-based TACE inhibitors von Li, Dansu, Popovici-Muller, Janeta, Belanger, David B., Caldwell, John, Dai, Chaoyang, David, Maria, Girijavallabhan, Vinay M., Lavey, Brian J., Lee, Joe F., Liu, Zhidan, Mazzola, Rob, Rizvi, Razia, Rosner, Kristin E., Shankar, Bandarpalle, Spitler, Jim, Ting, Pauline C., Vaccaro, Henry, Yu, Wensheng, Zhou, Guowei, Zhu, Zhaoning, Niu, Xiaoda, Sun, Jing, Guo, Zhuyan, Orth, Peter, Chen, Shiying, Kozlowski, Joseph A., Lundell, Daniel J., Madison, Vincent, McKittrick, Brian, Piwinski, John J., Shih, Neng-Yang, Shipps, Gerald W., Siddiqui, M. Arshad, Strickland, Corey O.

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(Alkylthio)alkynes as Addends in the Co(0) Catalyzed Intramolecular Pauson-Khand Reaction. Substituent Driven Enhancements of Annulation Efficiency and Stereoselectivity von Pagenkopf, Brian L., Belanger, David B., O'Mahony, Donogh J. R., Livinghouse, Tom

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The discovery of novel tartrate-based TNF-a converting enzyme (TACE) inhibitors von Rosner, Kristin E, Guo, Zhuyan, Orth, Peter, Shipps, Gerald W, Belanger, David B, Chan, Tin Yau, Curran, Patrick J, Dai, Chaoyang, Deng, Yongqi, Girijavallabhan, Vinay M, Hong, Liwu, Lavey, Brian J, Lee, Joe F, Li, Dansu, Liu, Zhidan, Popovici-Muller, Janeta, Ting, Pauline C, Vaccaro, Henry, Wang, Li, Wang, Tong, Yu, Wensheng, Zhou, Guowei, Niu, Xiaoda, Sun, Jing, Kozlowski, Joseph A, Lundell, Daniel J, Madison, Vincent, McKittrick, Brian, Piwinski, John J, Shih, Neng-Yang, Siddiqui, MArshad, Strickland, Corey O

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On the Counterion Dependence of the Rhodium(I)-Catalysed [4 + 2] Cycloaddition - A Remarkable Accelerating Effect of the Hexafluoroantimonate Anion von O'Mahony, Donogh J. R., Belanger, David B., Livinghouse, Tom

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The Discovery of (S)‑1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro‑1H‑inden-4-yl)pyridin-2-yl)-5-methyl‑1H‑pyrazole-4-carboxylic Acid, a So... von Ehara, Takeru, Adams, Christopher M, Bevan, Doug, Ji, Nan, Meredith, Erik L, Belanger, David B, Powers, James, Kato, Mitsunori, Solovay, Catherine, Liu, Donglei, Capparelli, Michael, Bolduc, Philippe, Grob, Jonathan E, Daniels, Matthew H, Ferrara, Luciana, Yang, Louis, Li, Byron, Towler, Christopher S, Stacy, Rebecca C, Prasanna, Ganesh, Mogi, Muneto

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Hexacarbonyldicobalt-alkyne complexes as convenient Co2(CO)8 surrogates in the catalytic Pauson-Khand reaction von Belanger, David B., Livinghouse, Tom

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