Review Article: Genetics of Alzheimer Disease von Bekris, Lynn M., Yu, Chang-En, Bird, Thomas D., Tsuang, Debby W.

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TREM2 alters the phagocytic, apoptotic and inflammatory response to Aβ42 in HMC3 cells von Akhter, Rumana, Shao, Yvonne, Formica, Shane, Khrestian, Maria, Bekris, Lynn M.

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Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease von Kam, Tae-In, Mao, Xiaobo, Park, Hyejin, Chou, Shih-Ching, Karuppagounder, Senthilkumar S, Umanah, George Essien, Yun, Seung Pil, Brahmachari, Saurav, Panicker, Nikhil, Chen, Rong, Andrabi, Shaida A, Qi, Chen, Poirier, Guy G, Pletnikova, Olga, Troncoso, Juan C, Bekris, Lynn M, Leverenz, James B, Pantelyat, Alexander, Ko, Han Seok, Rosenthal, Liana S, Dawson, Ted M, Dawson, Valina L

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The Genetics of Parkinson Disease von Bekris, Lynn M., Mata, Ignacio F., Zabetian, Cyrus P.

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Genetics of Alzheimer disease von Bekris, Lynn M, Yu, Chang-En, Bird, Thomas D, Tsuang, Debby W

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DNA methylation of TOMM40-APOE-APOC2 in Alzheimer's disease von Shao, Yvonne, Shaw, McKenzie, Todd, Kaitlin, Khrestian, Maria, D'Aleo, Giana, Barnard, P John, Zahratka, Jeff, Pillai, Jagan, Yu, Chang-En, Keene, C Dirk, Leverenz, James B, Bekris, Lynn M

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Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects von Li, Ge, Peskind, Elaine R, Millard, Steven P, Chi, Peter, Sokal, Izabela, Yu, Chang-En, Bekris, Lynn M, Raskind, Murray A, Galasko, Douglas R, Montine, Thomas J

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Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE von Bekris, Lynn M, Lutz, Franziska, Yu, Chang-En

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TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models von Jay, Taylor R, Miller, Crystal M, Cheng, Paul J, Graham, Leah C, Bemiller, Shane, Broihier, Margaret L, Xu, Guixiang, Margevicius, Daniel, Karlo, J Colleen, Sousa, Gregory L, Cotleur, Anne C, Butovsky, Oleg, Bekris, Lynn, Staugaitis, Susan M, Leverenz, James B, Pimplikar, Sanjay W, Landreth, Gary E, Howell, Gareth R, Ransohoff, Richard M, Lamb, Bruce T

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Multimodal single-cell/nucleus RNA sequencing data analysis uncovers molecular networks between disease-associated microglia and astrocytes with implications for drug repurposing i... von Xu, Jielin, Zhang, Pengyue, Huang, Yin, Zhou, Yadi, Hou, Yuan, Bekris, Lynn M, Lathia, Justin, Chiang, Chien-Wei, Li, Lang, Pieper, Andrew A, Leverenz, James B, Cummings, Jeffrey, Cheng, Feixiong

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AlzGPS: a genome-wide positioning systems platform to catalyze multi-omics for Alzheimer's drug discovery von Zhou, Yadi, Fang, Jiansong, Bekris, Lynn M, Kim, Young Heon, Pieper, Andrew A, Leverenz, James B, Cummings, Jeffrey, Cheng, Feixiong

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Regulation of ADAM10 by miR-140-5p and potential relevance for Alzheimer's disease von Akhter, Rumana, Shao, Yvonne, Shaw, McKenzie, Formica, Shane, Khrestian, Maria, Leverenz, James B., Bekris, Lynn M.

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A Computational Approach in the Systematic Search of the Interaction Partners of Alternatively Spliced TREM2 Isoforms von Liang, Junyi, Menon, Aditya, Tomco, Taylor, Bhattarai, Nisha, Smith, Iris Nira, Khrestian, Maria, Formica, Shane V, Eng, Charis, Buck, Matthias, Bekris, Lynn M

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TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis von Van Deerlin, Vivianna M, MD, Leverenz, James B, MD, Bekris, Lynn M, PhD, Bird, Thomas D, MD, Yuan, Wuxing, MS, Elman, Lauren B, MD, Clay, Dana, MS, Wood, Elisabeth McCarty, MS, Chen-Plotkin, Alice S, MD, Martinez-Lage, Maria, MD, Steinbart, Ellen, MA, McCluskey, Leo, MD, Grossman, Murray, MD, Neumann, Manuela, MD, Wu, I-Lin, MS, Yang, Wei-Shiung, MD, Kalb, Robert, MD, Galasko, Douglas R, MD, Montine, Thomas J, MD, Trojanowski, John Q, MD, Lee, Virginia M-Y, PhD, Schellenberg, Gerard D, PhD, Yu, Chang-En, PhD

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Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer’s disease von Xu, Jielin, Mao, Chengsheng, Hou, Yuan, Luo, Yuan, Binder, Jessica L., Zhou, Yadi, Bekris, Lynn M., Shin, Jiyoung, Hu, Ming, Wang, Fei, Eng, Charis, Oprea, Tudor I., Flanagan, Margaret E., Pieper, Andrew A., Cummings, Jeffrey, Leverenz, James B., Cheng, Feixiong

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Potential role of miRNA-140 in Alzheimer's disease von Akhter, Rumana, Bekris, Lynn M

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Temporal Ordering of Inflammatory Analytes sTNFR2 and sTREM2 in Relation to Alzheimer's Disease Biomarkers and Clinical Outcomes von Pillai, Jagan A, Khrestian, Maria, Bena, James, Leverenz, James B, Bekris, Lynn M

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An Altered Relationship between Soluble TREM2 and Inflammatory Markers in Young Adults with Down Syndrome: A Preliminary Report von Weber, Grace E, Koenig, Katherine A, Khrestian, Maria, Shao, Yvonne, Tuason, Elizabeth D, Gramm, Marie, Lal, Dennis, Leverenz, James B, Bekris, Lynn M

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Peripheral sTREM2-Related Inflammatory Activity Alterations in Early-Stage Alzheimer's Disease von Weber, Grace E, Khrestian, Maria, Tuason, Elizabeth D, Shao, Yvonne, Pillai, Jagan, Rao, Stephen, Feng, Hao, Zhou, Yadi, Cheng, Feixiong, DeSilva, Tara M, Stauffer, Shaun, Leverenz, James B, Bekris, Lynn M

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Emerging blood-based biomarkers for Alzheimer disease von Bekris, Lynn M, Leverenz, James B

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