Biology- Inspired Microphysiological Systems to Advance Patient Benefit and Animal Welfare in Drug Development von Marx, Uwe, Akabane, Takafumi, Andersson, Tommy B., Baker, Elizabeth, Beilmann, Mario, Beken, Sonja, Brendler-Schwaab, Susanne, Cirit, Murat, David, Rhiannon, Dehne, Eva-Maria, Durieux, Isabell, Ewart, Lorna, Fitzpatrick, Suzanne C., Frey, Olivier, Fuchs, Florian, Griffith, Linda G., Hamilton, Geraldine A., Hartung, Thomas, Hoeng, Julia, Hogberg, Helena, Hughes, David J., Ingber, Donald E., Iskandar, Anita, Kanamori, Toshiyuki, Kojima, Hajime, Kuehnl, Jochen, Leist, Marcel, Li, Bo, Loskill, Peter, Mendrick, Donna L., Neumann, Thomas, Pallocca, Giorgia, Rusyn, Ivan, Smirnova, Lena, Steger-Hartmann, Thomas, Tagle, Danilo A., Tonevitsky, Alexander, Tsyb, Sergej, Trapecar, Martin, van de Water, Bob, van den Eynden-van Raaij, Janny, Vultoy, Paul, Watanabe, Kengo, Wolf, Armin, Zhou, Xiaobing, Roth, Adrian

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Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing von Marx, Uwe

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EMA commentary on the ICH guideline for testing for carcinogenicity of pharmaceuticals von Laan, Jan Willem, Andersson, Mikael, Beken, Sonja, Bonelli, Milton, Brendler‐Schwaab, Susanne, Kane, Rosemary, Pasanen, Markku, Ponzano, Stefano, Paur, Jakob, Siezen, Christine, Soleng, Anne, Whomsley, Rhys

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Impact analysis of ICH S9 on non-clinical development of anticancer drugs von Bonelli, Milton, Di Giuseppe, Francesca, Beken, Sonja

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Taking the leap toward human-specific nonanimal methodologies: The need for harmonizing global policies for microphysiological systems von Parvatam, Surat, Pamies, David, Pistollato, Francesca, Beken, Sonja, Mariappan, Indumathi, Roth, Adrian, Piergiovanni, Monica, G C Maisonneuve, Benoît, Ewart, Lorna, Majumder, Abhijit, Dandekar, Prajakta, Date, Rahul, Mahadik, Kasturi, Thiyagarajan, Saravanan, Coecke, Sandra

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Exposure considerations in human safety assessment: Report from an EPAA Partners’ Forum von Cronin, Mark T.D., Ball, Nicholas, Beken, Sonja, Bender, Hans, Bercaru, Ofelia, Caneva, Laura, Corvaro, Marco, Currie, Richard A., Dawson, Jeffrey L., Desert, Paul, Escher, Sylvia E., Franco, Antonio, Irizar, Amaia, Mehta, Jyotigna M., Rogiers, Vera, Tremblay, Raphaël T., Westmoreland, Carl, Maxwell, Gavin

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Opportunities for use of one species for longer-term toxicology testing during drug development: A cross-industry evaluation von Prior, Helen, Baldrick, Paul, Beken, Sonja, Booler, Helen, Bower, Nancy, Brooker, Paul, Brown, Paul, Burlinson, Brian, Burns-Naas, Leigh Ann, Casey, Warren, Chapman, Melissa, Clarke, David, de Haan, Lolke, Doehr, Olaf, Downes, Noel, Flaherty, Meghan, Gellatly, Nichola, Moesgaard, Sophia Gry, Harris, Jennifer, Holbrook, Mark, Hui, Julia, Jones, David, Jones, Keith, Kedar, Hilla, Mahl, Andreas, Manninen, Alli, McGuire, Aidan, Mortimer-Cassen, Elisabeth, Peraza, Marjorie, Pugsley, Michael K., Richard, Jacques, Roberts, Ruth, Roosen, Wendy, Rothfuss, Andreas, Schoenmakers, Ankie, Sewell, Fiona, Weaver, Richard, Weir, Lucinda, Wolfreys, Alison, Kimber, Ian

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Role of standards and funding in accelerating the development and use of microphysiological systems von Parvatam, Surat, Mittal, Harshita, Pistollato, Francesca, Mahadik, Kasturi, Ewart, Lorna, Majumder, Abhijit, Gupta, Y.K, Beken, Sonja, Adhiseshan, Rajeshwari, Stacey, Glyn, Gandhi, Vishal, Kumar, Dhiraj, Constantino, Helder, Nayak, Goutami, Ghurde, Tejaswini, Gupta, Mousumi, Sengupta, Alokparna, Seidle, Troy

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Impact of Silver Nanoparticles on Haemolysis, Platelet Function and Coagulation von Laloy, Julie, Minet, Valentine, Alpan, Lutfiye, Mullier, François, Beken, Sonja, Toussaint, Olivier, Lucas, Stéphane, Dogné, Jean-Michel

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3Rs implementation in veterinary vaccine batch-release testing: Current state-of-the-art and future opportunities. A webinar and workshop report von Viviani, Laura, Balks, Elisabeth, Beken, Sonja, Brady, Anna-Maria, Clayton, Rick, Cliquet, Florence, Desmayanti, Liys, Fragoeiro, Silvia, Hamtak, Terrie Jo, John, David, Jungbaëck, Carmen, Kalaivani, M., Kross, Imke, Lang, Catherine, Ria Isriyanthi, Ni Made, Mallet, Laurent, Milne, Catherine, Rubbrecht, Michelle, Siklódi, Botond, Singh, Brajesh, Srinivas, Geetha B., Stickings, Paul, Stirling, Catrina, Sundram, Pushpanathan, Szabó, Mária, Thomas, Anne, van den Berg, Mariette, Walker, Angela, Philippe, Corinne, Vandeputte, Joris

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Considerations from an International Regulatory and Pharmaceutical Industry (IQ MPS Affiliate) Workshop on the Standardization of Complex In Vitro Models in Drug Development von Tomlinson, Lindsay, Ramsden, Diane, Leite, Sofia Batista, Beken, Sonja, Bonzo, Jessica A., Brown, Paul, Candarlioglu, Pelin L., Chan, Tom S., Chen, Eugene, Choi, Colin K., David, Rhiannon, Delrue, Nathalie, Devine, Patrick J., Ford, Kevin, Garcia, Martha Iveth, Gosset, James R., Hewitt, Philip, Homan, Kimberly, Irrechukwu, Onyi, Kopec, Anna K., Liras, Jennifer L., Mandlekar, Sandhya, Raczynski, Arek, Sadrieh, Nakissa, Sakatis, Melanie Z., Siegel, Jeffrey, Sung, Kyung, Sunyovszki, Ilona, Van Vleet, Terry R., Ekert, Jason E., Hardwick, Rhiannon N.

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Knowledge sharing to facilitate regulatory decision-making in regard to alternatives to animal testing: Report of an EPAA workshop von Ramirez, Tzutzuy, Beken, Sonja, Chlebus, Magda, Ellis, Graham, Griesinger, Claudius, De Jonghe, Sandra, Manou, Irene, Mehling, Annette, Reisinger, Kerstin, Rossi, Laura H., van Benthem, Jan, van der Laan, Jan Willem, Weissenhorn, Renate, Sauer, Ursula G.

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Cross-industry data survey of the value of rabbit developmental toxicity data in the risk assessment for pharmaceutics von Stewart, Jane, Piersma, Aldert H., Theunissen, Peter T., Cappon, Greg D., Beken, Sonja

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Hepatocyte polarity and the peroxisomal compartment: a comparative study von Depreter, Marianne, Walker, Tracy, De Smet, Karen, Beken, Sonja, Kerckaert, Ingrid, Rogiers, Vera, Roels, Frank

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Regulatory acceptance and use of 3R models for pharmaceuticals and chemicals: Expert opinions on the state of affairs and the way forward von Schiffelers, Marie-Jeanne W.A., Blaauboer, Bas J., Bakker, Wieger E., Beken, Sonja, Hendriksen, Coenraad F.M., Koëter, Herman B.W.M., Krul, Cyrille

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Cross-industry data survey of the value of rabbit developmental toxicity data in the risk assessment for pharmaceutics: Sponsored by ILSI Health and Environmental Sciences Institut... von Stewart, Jane, Piersma, Aldert H., Theunissen, Peter T., Cappon, Greg D., Beken, Sonja

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Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing von Marx, Uwe, Andersson, Tommy B, Bahinski, Anthony, Beilmann, Mario, Beken, Sonja, Cassee, Flemming R, Cirit, Murat, Daneshian, Mardas, Fitzpatrick, Susan, Frey, Olivier, Gaertner, Claudia, Giese, Christoph, Griffith, Linda, Hartung, Thomas, Heringa, Minne B, Hoeng, Julia, de Jong, Wim H, Kojima, Hajime, Kuehnl, Jochen, Leist, Marcel, Luch, Andreas, Maschmeyer, Ilka, Sakharov, Dmitry, Sips, Adrienne J A M, Steger-Hartmann, Thomas, Tagle, Danilo A, Tonevitsky, Alexander, Tralau, Tewes, Tsyb, Sergej, van de Stolpe, Anja, Vandebriel, Rob, Vulto, Paul, Wang, Jufeng, Wiest, Joachim, Rodenburg, Marleen, Roth, Adrian

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Effects of extracellular matrix on the expression of peroxisomes in primary rat hepatocyte cultures von DEPRETER, M, TYTGAT, T, BEKEN, S, ESPEEL, M, DE SMET, K, ROGIERS, V, ROELS, F

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Launch of the Belgian Platform for Alternative Methods von Rogiers, Vera, Beken, Sonja

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Glutathione transferase activities in renal carcinomas and adjacent normal renal tissues : factors influencing renal carcinogenesis induced by xenobiotics von DELBANCO, Evert H, BOLT, Hermann M, HUBER, Wolfgang W, BEKEN, Sonja, GELLER, Frank, PHILIPPOU, Stathis, BRANDS, Frank H, BRÜNING, Thomas, THIER, Ricarda

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