The Janus kinase 2 inhibitor fedratinib inhibits thiamine uptake: a putative mechanism for the onset of Wernicke's encephalopathy von Zhang, Qiang, Zhang, Yan, Diamond, Sharon, Boer, Jason, Harris, Jennifer J, Li, Yu, Rupar, Mark, Behshad, Elham, Gardiner, Christine, Collier, Paul, Liu, Phillip, Burn, Timothy, Wynn, Richard, Hollis, Gregory, Yeleswaram, Swamy

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Kinetic Analysis of Cysteine Desulfurase CD0387 from Synechocystis sp. PCC 6803: Formation of the Persulfide Intermediate von Behshad, Elham, Bollinger, J. Martin

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A Locking Mechanism Preventing Radical Damage in the Absence of Substrate, as Revealed by the X-Ray Structure of Lysine 5,6-Aminomutase von Berkovitch, Frederick, Behshad, Elham, Tang, Kuo-Hsiang, Enns, Eva A., Frey, Perry A., Drennan, Catherine L.

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Mechanism of Cysteine Desulfurase Slr0387 from Synechocystis sp. PCC 6803:  Kinetic Analysis of Cleavage of the Persulfide Intermediate by Chemical Reductants von Behshad, Elham, Parkin, Sara E, Bollinger, J. Martin

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Variability in Virulence Gene Prevalence Among Uropathogenic Escherichia coli Isolates: Implications for Understanding UTI Pathogenesis von Behshad, Elham, Rashki, Ahmad, Hadadi, Fatemeh, shahkarami, Fatemeh, Shabani, Sadeq

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Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor von Koblish, Holly K, Wu, Liangxing, Wang, Liang-Chuan S, Liu, Phillip C C, Wynn, Richard, Rios-Doria, Jonathan, Spitz, Susan, Liu, Hao, Volgina, Alla, Zolotarjova, Nina, Kapilashrami, Kanishk, Behshad, Elham, Covington, Maryanne, Yang, Yan-Ou, Li, Jingwei, Diamond, Sharon, Soloviev, Maxim, O'Hayer, Kevin, Rubin, Stephen, Kanellopoulou, Chrysi, Yang, Gengjie, Rupar, Mark, DiMatteo, Darlise, Lin, Luping, Stevens, Christina, Zhang, Yue, Thekkat, Pramod, Geschwindt, Ryan, Marando, Cindy, Yeleswaram, Swamy, Jackson, Jeff, Scherle, Peggy, Huber, Reid, Yao, Wenqing, Hollis, Gregory

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Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders von Li, Zhenwu, Harikrishnan, Lalgudi S, Xu, Guozhang, Samanta, Debangshu, Clemente, Jose C, Leng, Lingying, Tu, Wenbin, Yang, Lin, Huang, Liyue, Wang, Mi, Wang, Shaomeng, Deng, Qiaolin, Behshad, Elham, Nagilla, Rakesh, Orth, Peter, Rice, Cory, Strickland, Corey, Mohammad, Helai P, Priestley, E Scott, Sui, Zhihua

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A Novel Kinase Inhibitor, INCB28060, Blocks c-MET-Dependent Signaling, Neoplastic Activities, and Cross-Talk with EGFR and HER-3 von XIANGDONG LIU, QIAN WANG, BOER, Jason, DIAMOND, Sharon, CHUNHONG HE, MEIZHONG XU, JINCONG ZHUO, WENQING YAO, NEWTON, Robert C, SCHERLE, Peggy A, GENGJIE YANG, MARANDO, Cindy, KOBLISH, Holly K, HALL, Leslie M, FRIDMAN, Jordan S, BEHSHAD, Elham, WYNN, Richard, YU LI

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Abstract LB174: Discovery and preclinical characterization of INCA00186, a humanized monoclonal antibody antagonist of CD73, as a cancer immunotherapy von Stewart, Shaun, Buonpane, Rebecca, Zhou, Jing, Hansbury, Michael, Smith, Michael, Wang, Hui, Lu, Su, Bin, Awdew, Rahel, Huang, Cheng-Yen, Kulkarni, Ashwini, Harvey, Shane, Mondal, Arpita, Wang, Steve, Stevens, Christina, Pratta, Michael, Behshad, Elham, Fanuka, Alexandra, Ren, Xiaodi, Koblish, Holly, Nastri, Horacio, Mayes, Patrick

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Discovery of Pyrazolopyridine Derivatives as HPK1 Inhibitors von Ye, Qinda, Liu, Kai, Ye, Hai-Fen, Pan, Jun, Sokolsky, Alexander, Wang, Anlai, Zhang, Ke, Hummel, Joshua R., Kong, Ling, Behshad, Elham, He, Xin, Conlen, Patricia, Stump, Kristine, Ye, Min, Diamond, Sharon, Covington, Maryanne, Yeleswaram, Swamy, Atasoylu, Onur, Vechorkin, Oleg, Yao, Wenqing

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Potent and Selective Biaryl Amide Inhibitors of Hematopoietic Progenitor Kinase 1 (HPK1) von Sokolsky, Alexander, Vechorkin, Oleg, Hummel, Joshua R., Styduhar, Evan D., Wang, Anlai, Nguyen, Minh H., Ye, Hai Fen, Liu, Kai, Zhang, Ke, Pan, Jun, Ye, Qinda, Atasoylu, Onur, Behshad, Elham, He, Xin, Conlen, Patricia, Stump, Kristine, Ye, Min, Diamond, Sharon, Covington, Maryanne, Yeleswaram, Swamy, Yao, Wenqing

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Abstract 4513: The role of HPK1 in the regulation of T cell function and anti-tumor immune activity von Chen, Yaoyu, Rios-Doria, Jonathan, Pusey, Michelle, Lasky, Kerri, Ye, Min, Thekkat, Pramod, Gallagher, Karen, Stump, Kristine, Conlen, Patricia, Gardiner, Christine, Wang, Hui, Sokolsky, Alexander, Rupar, Mark, Lin, Luping, Behshad, Elham, Covington, Maryanne, Koblish, Holly, Vechorkin, Oleg, Yao, Wenqing, Kim, Sunkyu, Chen, Yingnan

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Discovery of Orally Bioavailable FGFR2/FGFR3 Dual Inhibitors via Structure-Guided Scaffold Repurposing Approach von Nguyen, Minh H., Ye, Hai-Fen, Xu, Yao, Truong, Lisa, Horsey, April, Zhao, Peng, Styduhar, Evan D., Frascella, Michelle, Leffet, Lynn, Federowicz, Kelly, Behshad, Elham, Wang, Anlai, Zhang, Ke, Witten, Michael R., Qi, Chao, Jalluri, Ravi, Lai, Cheng-Tsung, Atasoylu, Onur, Harris, Jennifer J., Hess, Rodrigo, Lin, Luping, Zhang, Guofeng, Covington, Maryanne, Diamond, Sharon, Yao, Wenqing, Vechorkin, Oleg

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232 INCB090244, a potent small molecule that inhibits the PD-L1/PD-1 axis and functions similarly to PD-L1 antibodies von Rios-Doria, Jonathan, Volgina, Alla, Gokhale, Prafulla, Liu, Hao, Stevens, Christina, Zolotarjova, Nina, DiMatteo, Darlise, Kapilashrami, Kanishk, Behshad, Elham, Thekkat, Pramod, Yang, Gengjie, Hall, Leslie, Kanellopoulou, Chrysi, Rupar, Mark, Maddage, Christopher, Horsey, April, Burke, Krista, Yang, Yan-ou, Covington, Maryanne, Wang, Steve, Liu, Phillip, Wynn, Richard, Reardon, David, Koblish, Holly

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Abstract B191: Preclinical assessment of targeting the PI3K/AKT pathway in combination with other signal transduction pathway inhibitors von Lee, Sang Hyun, Koblish, Holly, Liu, Xiangdong, Ye, Haifen, Li, Jun, Liu, Xuesong, Diamond, Melody, Zhang, Yue, Hall, Leslie, Dostalik, Valerie, Favata, Margaret, Behshad, Elham, Wynn, Richard, Li, Yun-long, Combs, Andrew, Xue, Chu-Bio, Yao, Wenqing, Hollis, Gregory, Huber, Reid, Scherle, Peggy

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Evidence for Conformational Movement and Radical Mechanism in the Reaction of 4-Thia-l-lysine with Lysine 5,6-Aminomutase von Maity, Amarendra N, Hsieh, Chih-Pin, Huang, Ming-Hui, Chen, Yung-Han, Tang, Kuo-Hsiang, Behshad, Elham, Frey, Perry A, Ke, Shyue-Chu

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How an Enzyme Tames Reactive Intermediates:  Positioning of the Active-Site Components of Lysine 2,3-Aminomutase during Enzymatic Turnover As Determined by ENDOR Spectroscopy von Lees, Nicholas S, Chen, Dawei, Walsby, Charles J, Behshad, Elham, Frey, Perry A, Hoffman, Brian M

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Phosphorylation State-Dependent High Throughput Screening of the c-Met Kinase von Behshad, Elham, Klabe, Ronald M, Margulis, Alexander, Becker-Pasha, Mary, Rupar, Mark J, Collier, Paul, Liu, Phillip C, Hollis, Gregory F, Burn, Timothy C, Wynn, Richard

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Solidification enhancement in triplex thermal energy storage system via triplets fins configuration and hybrid nanoparticles von Hosseinzadeh, Kh, Montazer, Elham, Shafii, Mohammad Behshad, Ganji, A.R.D.

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Heat transfer hybrid nanofluid (1-Butanol/MoS2–Fe3O4) through a wavy porous cavity and its optimization von Hosseinzadeh, Kh, Montazer, Elham, Shafii, Mohammad Behshad, Ganji, D.D

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