The Translational Science Benefits Model: A New Framework for Assessing the Health and Societal Benefits of Clinical and Translational Sciences von Luke, Douglas A., Sarli, Cathy C., Suiter, Amy M., Carothers, Bobbi J., Combs, Todd B., Allen, Jae L., Beers, Courtney E., Evanoff, Bradley A.

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Dose escalation results from a first-in-human, phase 1 study of glucocorticoid-induced TNF receptor-related protein agonist AMG 228 in patients with advanced solid tumors von Tran, Ben, Carvajal, Richard D, Marabelle, Aurelien, Patel, Sandip Pravin, LoRusso, Patricia M, Rasmussen, Erik, Juan, Gloria, Upreti, Vijay V, Beers, Courtney, Ngarmchamnanrith, Gataree, Schöffski, Patrick

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Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism von Spatola, Bradley N., Lerner, Alana G., Wong, Clifford, dela Cruz, Tracy, Welch, Megan, Fung, Wanchi, Kovalenko, Maria, Losenkova, Karolina, Yegutkin, Gennady G., Beers, Courtney, Corbin, John, Soros, Vanessa B.

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Factors Affecting Parent and Child Play Experiences During the COVID-19 Spread and Initial Social Distancing Efforts von Casey, Erin, Dewhirst, Courtney Beers, Unsicker-Durham, Shelly K., Nahar, Gul, Wescoup, Stephanie M.

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Cellular and plasma proteomic determinants of COVID-19 and non-COVID-19 pulmonary diseases relative to healthy aging von Arthur, Laura, Esaulova, Ekaterina, Mogilenko, Denis A., Tsurinov, Petr, Burdess, Samantha, Laha, Anwesha, Presti, Rachel, Goetz, Brian, Watson, Mark A., Goss, Charles W., Gurnett, Christina A., Mudd, Philip A., Beers, Courtney, O'Halloran, Jane A., Artyomov, Maxim N.

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698 Targeting HLA-G-mediated immunosuppression with a first-in-class antagonist antibody von Hodges, Douglas, Kochel, Christina, Totagrande, Michael, Jones, Jeffrey, Welch, Megan, Spatola, Bradley, Joe, Shelby, Corbin, John, Soros, Vanessa, Beers, Courtney, Moesta, Achim

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Listening to mothers’ voices of children’s play challenges and changes during social distancing von Dewhirst, Courtney Beers, Casey, Erin

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Regulation of thymic epithelium by keratinocyte growth factor von Erickson, Matthew, Morkowski, Stanislaw, Lehar, Sophie, Gillard, Geoffrey, Beers, Courtney, Dooley, James, Rubin, Jeffrey S., Rudensky, Alexander, Farr, Andrew G.

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Using an Exploratory Professional Development Initiative to Introduce iPads in the Early Childhood Education Classroom von Vaughan, Michelle, Beers, Courtney

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Targeting CD39 in Cancer Reveals an Extracellular ATP- and Inflammasome-Driven Tumor Immunity von Li, Xian-Yang, Moesta, Achim K, Xiao, Christos, Nakamura, Kyohei, Casey, Mika, Zhang, Haiyan, Madore, Jason, Lepletier, Ailin, Aguilera, Amelia Roman, Sundarrajan, Ashmitha, Jacoberger-Foissac, Celia, Wong, Clifford, Dela Cruz, Tracy, Welch, Megan, Lerner, Alana G, Spatola, Bradley N, Soros, Vanessa B, Corbin, John, Anderson, Ana C, Effern, Maike, Hölzel, Michael, Robson, Simon C, Johnston, Rebecca L, Waddell, Nicola, Smith, Corey, Bald, Tobias, Geetha, Nishamol, Beers, Courtney, Teng, Michele W L, Smyth, Mark J

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Breast cancer presentation in an urban health care Safety Net system von Fayanju, Oluwadamilola M, Jeffe, Donna B, Tappenden, Jennifer R, Beers, Courtney E, Drake, Bettina F, Gao, Feng, Margenthaler, Julie A

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Surgical removal of the primary tumor increases overall survival in patients with metastatic breast cancer: analysis of the 1988-2003 SEER data von Gnerlich, Jennifer, Jeffe, Donna B, Deshpande, Anjali D, Beers, Courtney, Zander, Christina, Margenthaler, Julie A

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NKG2D splice variants: a reexamination of adaptor molecule associations von Rabinovich, Brian, Li, Jennifer, Wolfson, Martin, Lawrence, William, Beers, Courtney, Chalupny, Jan, Hurren, Rose, Greenfield, Brad, Miller, Richard, Cosman, David

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Control of Metastases via Myeloid CD39 and NK Cell Effector Function von Yan, Juming, Li, Xian-Yang, Aguilera, Amelia Roman, Xiao, Christos, Jacoberger-Foisac, Celia, Nowlan, Bianca, Robson, Simon C., Beers, Courtney, Moesta, Achim K., Geetha, Nishamol, Teng, Michele W. L., Smyth, Mark J.

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Abstract 4287: Talimogene laherparepvec activates systemic T-cell-mediated anti-tumor immunity von Piasecki, Julia, Rottman, Jim, Le, Tiep, Ponce, Rafael, Beers, Courtney

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Abstract 258: Talilmogene laherparepvec increases the anti-tumor efficacy of the anti-PD-1 immune checkpoint blockade von Piasecki, Julia, le, Tiep, Ponce, Rafael, Beers, Courtney

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Joanne Knight Breast Health Cohort at Siteman Cancer Center von Colditz, Graham A., Bennett, Debbie L., Tappenden, Jennifer, Beers, Courtney, Ackermann, Nicole, Wu, Ningying, Luo, Jingqin, Humble, Sarah, Linnenbringer, Erin, Davis, Kia, Jiang, Shu, Toriola, Adetunji T.

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Structure-Function Studies of Interleukin 15 using Site-specific Mutagenesis, Polyethylene Glycol Conjugation, and Homology Modeling von Pettit, Dean K., Bonnert, Timothy P., Eisenman, June, Srinivasan, Subhashini, Paxton, Ray, Beers, Courtney, Lynch, Dave, Miller, Bob, Yost, Jeff, Grabstein, Kenneth H., Gombotz, Wayne R.

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Abstract 5012: Targeting CD39 with a first-in-class inhibitory antibody prevents ATP processing and increases T-cell activation von Lerner, Alana G., Kovalenko, Maria, Welch, Megan, Cruz, Tracy dela, Jones, Jeff, Wong, Clifford, Spatola, Bradley, Eberhardt, Meghan, Wong, Andrew, Fung, Wanchi, Lagpacan, Leanna, Losenkova, Karolina, Yegutkin, Gennady, Soros, Vanessa, Corbin, John, Beers, Courtney, Moesta, Achim K.

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Positive Selection of Self-MHC-Reactive T Cells by Individual Peptide-MHC Class II Complexes von Barton, Gregory M., Beers, Courtney, deRoos, Paul, Eastman, Susan R., Gomez, Marcela E., Forbush, Katherine A., Rudensky, Alexander Y.

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