Broad spectrum of regorafenib activity on mutant KIT and absence of clonal selection in gastrointestinal stromal tumor (GIST): correlative analysis from the GRID trial von Jeffers, Michael, Kappeler, Christian, Kuss, Iris, Beckmann, Georg, Mehnert, Daniel H., Fredebohm, Johannes, Teufel, Michael

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Single-agent activity of phosphatidylinositol 3-kinase inhibition with copanlisib in patients with molecularly defined relapsed or refractory diffuse large B-cell lymphoma von Lenz, Georg, Hawkes, Eliza, Verhoef, Gregor, Haioun, Corinne, Thye Lim, Soon, Seog Heo, Dae, Ardeshna, Kirit, Chong, Geoffrey, Haaber, Jacob, Shi, Wei, Gorbatchevsky, Igor, Lippert, Susanne, Hiemeyer, Florian, Piraino, Paolo, Beckmann, Georg, Peña, Carol, Buvaylo, Viktoriya, Childs, Barrett H., Salles, Gilles

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EZH2 Inhibition Blocks Multiple Myeloma Cell Growth through Upregulation of Epithelial Tumor Suppressor Genes von Hernando, Henar, Gelato, Kathy A, Lesche, Ralf, Beckmann, Georg, Koehr, Silke, Otto, Saskia, Steigemann, Patrick, Stresemann, Carlo

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T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction von Pinkert, Jessica, Boehm, Hans-Henning, Trautwein, Mark, Doecke, Wolf-Dietrich, Wessel, Florian, Ge, Yingzi, Gutierrez, Eva Maria, Carretero, Rafael, Freiberg, Christoph, Gritzan, Uwe, Luetke-Eversloh, Merlin, Golfier, Sven, Von Ahsen, Oliver, Volpin, Valentina, Sorrentino, Antonio, Rathinasamy, Anchana, Xydia, Maria, Lohmayer, Robert, Sax, Julian, Nur-Menevse, Ayse, Hussein, Abir, Stamova, Slava, Beckmann, Georg, Glueck, Julian Marius, Schoenfeld, Dorian, Weiske, Joerg, Zopf, Dieter, Offringa, Rienk, Kreft, Bertolt, Beckhove, Philipp, Willuda, Joerg

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Exon array analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer von Langer, Wolfram, Sohler, Florian, Leder, Gabriele, Beckmann, Georg, Seidel, Henrik, Gröne, Jörn, Hummel, Michael, Sommer, Anette

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AKT1 E17K mutation profiling in breast cancer: prevalence, concurrent oncogenic alterations, and blood-based detection von Rudolph, Marion, Anzeneder, Tobias, Schulz, Anke, Beckmann, Georg, Byrne, Annette T., Jeffers, Michael, Pena, Carol, Politz, Oliver, Köchert, Karl, Vonk, Richardus, Reischl, Joachim

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Molecular profiles and clinical outcome of stage UICC II colon cancer patients von Gröne, Jörn, Lenze, Dido, Jurinovic, Vindi, Hummel, Manuela, Seidel, Henrik, Leder, Gabriele, Beckmann, Georg, Sommer, Anette, Grützmann, Robert, Pilarsky, Christian, Mansmann, Ulrich, Buhr, Heinz-Johannes, Stein, Harald, Hummel, Michael

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Comparative thermodynamic analysis of an improved ORC process with integrated injection of process fluid von Krail, Jürgen, Beckmann, Georg, Schittl, Florian, Piringer, Gerhard

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A genetics-led approach defines the drug target landscape of 30 immune-related traits von Fang, Hai, De Wolf, Hans, Knezevic, Bogdan, Burnham, Katie L., Osgood, Julie, Sanniti, Anna, Lledó Lara, Alicia, Kasela, Silva, De Cesco, Stephane, Wegner, Jörg K., Handunnetthi, Lahiru, McCann, Fiona E., Chen, Liye, Sekine, Takuya, Brennan, Paul E., Marsden, Brian D., Damerell, David, O’Callaghan, Chris A., Bountra, Chas, Bowness, Paul, Sundström, Yvonne, Milani, Lili, Berg, Louise, Göhlmann, Hinrich W., Peeters, Pieter J., Fairfax, Benjamin P., Sundström, Michael, Knight, Julian C.

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AKT1 (E17K) mutation profiling in breast cancer: prevalence, concurrent oncogenic alterations, and blood-based detection von Rudolph, Marion, Anzeneder, Tobias, Schulz, Anke, Beckmann, Georg, Byrne, Annette T, Jeffers, Michael, Pena, Carol, Politz, Oliver, Köchert, Karl, Vonk, Richardus, Reischl, Joachim

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AKT1E17K mutation profiling in breast cancer: prevalence, concurrent oncogenic alterations, and blood-based detection von Rudolph, Marion, Anzeneder, Tobias, Schulz, Anke, Beckmann, Georg, Byrne, Annette T, Jeffers, Michael, Pena, Carol, Politz, Oliver, Köchert, Karl, Vonk, Richardus, Reischl, Joachim

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An adhesive domain detected in functionally diverse receptors von Beckmann, Georg, Bork, Peer

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Correction: Single-agent activity of phosphatidylinositol 3-kinase inhibition with copanlisib in patients with molecularly defined relapsed or refractory diffuse large B-cell lymph... von Lenz, Georg, Hawkes, Eliza, Verhoef, Gregor, Haioun, Corinne, Thye Lim, Soon, Seog Heo, Dae, Ardeshna, Kirit, Chong, Geoffrey, Haaber, Jacob, Shi, Wei, Gorbatchevsky, Igor, Lippert, Susanne, Hiemeyer, Florian, Piraino, Paolo, Beckmann, Georg, Peña, Carol, Buvaylo, Viktoriya, Childs, Barrett H., Salles, Gilles

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Abstract CT020: Long-term outcomes of patients with TRK fusion cancer treated with larotrectinib von Drilon, Alexander, Kummar, Shivaani, Albert, Catherine M., Nagasubramanian, Ramamoorthy, Hechtman, Jaclyn F., Reeves, John A., Beckmann, Georg, Rudolph, Marion, Wierzbińska, Justyna A., Dima, Laura, Brega, Nicoletta, Laetsch, Theodore W., Hong, David S.

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Single-agent activity of phosphatidylinositol 3-kinase inhibition with copanlisib in patients with molecularly defined relapsed or refractory diffuse large B-cell lymphoma von Lenz, Georg, Hawkes, Eliza, Verhoef, Gregor, Haioun, Corinne, Thye Lim, Soon, Seog Heo, Dae, Ardeshna, Kirit, Chong, Geoffrey, Haaber, Jacob, Shi, Wei, Gorbatchevsky, Igor, Lippert, Susanne, Hiemeyer, Florian, Piraino, Paolo, Beckmann, Georg, Pena, Carol, Buvaylo, Viktoriya, Childs, Barrett H, Salles, Gilles

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Abstract 4035: Preclinical activity of BAY 2927088 in HER2 mutant non-small cell lung cancer von Siegel, Franziska, Karsli-Uzunbas, Gizem, Kotynkova, Kristyna, McVeigh, Quinn, Siegel, Stephan, Korr, Daniel, Schulze, Volker, Berger, Markus, Beckmann, Georg, Cherniack, Andrew, Meyerson, Matthew, Greulich, Heidi

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Analysis and decrease of the energy demand of bioethanol-production by process integration von Pfeffer, Martin, Wukovits, Walter, Beckmann, Georg, Friedl, Anton

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Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells von Prinz, Florian, Puetter, Vera, Holton, Simon J., Andres, Dorothee, Stegmann, Christian M., Kwiatkowski, Dennis, Prechtl, Stefan, Petersen, Kirstin, Beckmann, Georg, Kreft, Bertolt, Mumberg, Dominik, Fernández-Montalván, Amaury

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The CUB Domain: A Widespread Module in Developmentally Regulated Proteins von Bork, Peer, Beckmann, Georg

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Isogenic human mammary epithelial cell lines: novel tools for target identification and validation: Comprehensive characterization of an isogenic human mammary epithelial cell mode... von Ulbricht, Ulrike, Sommer, Anette, Beckmann, Georg, Lutzenberger, Manuel, Seidel, Henrik, Kreft, Bertolt, Toschi, Luisella

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