BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells von Lagadinou, Eleni D., Sach, Alexander, Callahan, Kevin, Rossi, Randall M., Neering, Sarah J., Minhajuddin, Mohammad, Ashton, John M., Pei, Shanshan, Grose, Valerie, O’Dwyer, Kristen M., Liesveld, Jane L., Brookes, Paul S., Becker, Michael W., Jordan, Craig T.

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Evolution of acute myelogenous leukemia stem cell properties after treatment and progression von Ho, Tzu-Chieh, LaMere, Mark, Stevens, Brett M., Ashton, John M., Myers, Jason R., O'Dwyer, Kristen M., Liesveld, Jane L., Mendler, Jason H., Guzman, Monica, Morrissette, Jennifer D., Zhao, Jianhua, Wang, Eunice S., Wetzler, Meir, Jordan, Craig T., Becker, Michael W.

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Flaming and fanning: The Spectrum of inflammatory influences in myelodysplastic syndromes von Banerjee, Titas, Calvi, Laura M., Becker, Michael W., Liesveld, Jane L.

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Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia von Frisch, Benjamin J., Ashton, John M., Xing, Lianping, Becker, Michael W., Jordan, Craig T., Calvi, Laura M.

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The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation von Zahreddine, Hiba Ahmad, Culjkovic-Kraljacic, Biljana, Assouline, Sarit, Gendron, Patrick, Romeo, Andrea A., Morris, Stephen J., Cormack, Gregory, Jaquith, James B., Cerchietti, Leandro, Cocolakis, Eftihia, Amri, Abdellatif, Bergeron, Julie, Leber, Brian, Becker, Michael W., Pei, Shanshan, Jordan, Craig T., Miller, Wilson H., Borden, Katherine L. B.

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Dysregulated gene expression networks in human acute myelogenous leukemia stem cells von Majeti, Ravindra, Becker, Michael W, Tian, Qiang, Lee, Tsung-Lu Michael, Yan, Xiaowei, Liu, Rui, Chiang, Jung-Hsien, Hood, Leroy, Clarke, Michael F, Weissman, Irving L

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Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells von Clarke, Michael F, Park, In-kyung, Qian, Dalong, Kiel, Mark, Becker, Michael W, Pihalja, Michael, Weissman, Irving L, Morrison, Sean J

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Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome von Balderman, Sophia R., Li, Allison J., Hoffman, Corey M., Frisch, Benjamin J., Goodman, Alexandra N., LaMere, Mark W., Georger, Mary A., Evans, Andrew G., Liesveld, Jane L., Becker, Michael W., Calvi, Laura M.

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Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells von Pei, Shanshan, Minhajuddin, Mohammad, Callahan, Kevin P., Balys, Marlene, Ashton, John M., Neering, Sarah J., Lagadinou, Eleni D., Corbett, Cheryl, Ye, Haobin, Liesveld, Jane L., O'Dwyer, Kristen M., Li, Zheng, Shi, Lei, Greninger, Patricia, Settleman, Jeffrey, Benes, Cyril, Hagen, Fred K., Munger, Joshua, Crooks, Peter A., Becker, Michael W., Jordan, Craig T.

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A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species von Zong, Hongliang, Gozman, Alexander, Caldas-Lopes, Eloisi, Taldone, Tony, Sturgill, Eric, Brennan, Sarah, Ochiana, Stefan O., Gomes-DaGama, Erica M., Sen, Siddhartha, Rodina, Anna, Koren, John, Becker, Michael W., Rudin, Charles M., Melnick, Ari, Levine, Ross L., Roboz, Gail J., Nimer, Stephen D., Chiosis, Gabriela, Guzman, Monica L.

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Therapeutic implications of cancer stem cells von Al-Hajj, Muhammad, Becker, Michael W, Wicha, Max, Weissman, Irving, Clarke, Michael F

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The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells von Adane, Biniam, Ye, Haobin, Khan, Nabilah, Pei, Shanshan, Minhajuddin, Mohammad, Stevens, Brett M., Jones, Courtney L., D’Alessandro, Angelo, Reisz, Julie A., Zaberezhnyy, Vadym, Gasparetto, Maura, Ho, Tzu-Chieh, Kelly, Kathleen K., Myers, Jason R., Ashton, John M., Siegenthaler, Julie, Kume, Tsutomu, Campbell, Eric L., Pollyea, Daniel A., Becker, Michael W., Jordan, Craig T.

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Prostaglandin E2 Increases Hematopoietic Stem Cell Survival and Accelerates Hematopoietic Recovery After Radiation Injury von Porter, Rebecca L., Georger, Mary A., Bromberg, Olga, McGrath, Kathleen E., Frisch, Benjamin J., Becker, Michael W., Calvi, Laura M.

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Efferocytosis by bone marrow mesenchymal stromal cells disrupts osteoblastic differentiation via mitochondrial remodeling von Quarato, Emily R., Salama, Noah A., Li, Allison J., Smith, Charles O., Zhang, Jane, Kawano, Yuko, McArthur, Matthew, Liesveld, Jane L., Becker, Michael W., Elliott, Michael R., Eliseev, Roman A., Calvi, Laura M.

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An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells von Guzman, Monica L., Rossi, Randall M., Neelakantan, Sundar, Li, Xiaojie, Corbett, Cheryl A., Hassane, Duane C., Becker, Michael W., Bennett, John M., Sullivan, Edmund, Lachowicz, Joshua L., Vaughan, Andrew, Sweeney, Christopher J., Matthews, William, Carroll, Martin, Liesveld, Jane L., Crooks, Peter A., Jordan, Craig T.

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In silico predicted compound targeting the IQGAP1-GRD domain selectively inhibits growth of human acute myeloid leukemia von Sahasrabudhe, Deepak M., Liesveld, Jane L., Minhajuddin, Mohammad, Singh, Niloy A., Nath, Subhangi, Kumar, Vishuwes Muthu, Balys, Marlene, Evans, Andrew G., Azadniv, Mitra, Hansen, Jeanne N., Becker, Michael W., Sharon, Ashoke, Thomas, V. Kaye, Moore, Richard G., Khera, Manoj K., Jordan, Craig T., Singh, Rakesh K.

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The roles of bone remodeling in normal hematopoiesis and age-related hematological malignancies von Zhang, Hengwei, Liesveld, Jane L, Calvi, Laura M, Lipe, Brea C, Xing, Lianping, Becker, Michael W, Schwarz, Edward M, Yeh, Shu-Chi A

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Dendritic cell-mimicking scaffolds for ex vivo T cell expansion von Kim, Hye Sung, Ho, Tzu-Chieh, Willner, Moshe J., Becker, Michael W., Kim, Hae-Won, Leong, Kam W.

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Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1 von Gasparetto, Maura, Pei, Shanshan, Minhajuddin, Mohammad, Khan, Nabilah, Pollyea, Daniel A, Myers, Jason R, Ashton, John M, Becker, Michael W, Vasiliou, Vasilis, Humphries, Keith R, Jordan, Craig T, Smith, Clayton A

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Patterns and Timing of Failure for Diffuse Large B-Cell Lymphoma After Initial Therapy in a Cohort Who Underwent Autologous Bone Marrow Transplantation for Relapse von Dhakal, Sughosh, MD, Bates, James E., MD, Casulo, Carla, MD, Friedberg, Jonathan W., MD, Becker, Michael W., MD, Liesveld, Jane L., MD, Constine, Louis S., MD

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