Reversal of human cellular senescence: roles of the p53 and p16 pathways von Campisi, Judith, Beauséjour, Christian M, Krtolica, Ana, Galimi, Francesco, Narita, Masashi, Lowe, Scott W, Yaswen, Paul

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p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes von Davalos, Albert R, Kawahara, Misako, Malhotra, Gautam K, Schaum, Nicholas, Huang, Jiahao, Ved, Urvi, Beausejour, Christian M, Coppe, Jean-Philippe, Rodier, Francis, Campisi, Judith

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DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion von Rodier, Francis, Muñoz, Denise P, Teachenor, Robert, Chu, Victoria, Le, Oanh, Bhaumik, Dipa, Coppé, Jean-Philippe, Campeau, Eric, Beauséjour, Christian M, Kim, Sahn-Ho, Davalos, Albert R, Campisi, Judith

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Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery von Genovese, Pietro, Galli, Cesare, Gregory, Philip D, Naldini, Luigi, Beausejour, Christian M, Colleoni, Silvia, Urnov, Fyodor D, Kim, Kenneth A, Ando, Dale, Lombardo, Angelo, Lee, Ya-Li, Holmes, Michael C

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An improved zinc-finger nuclease architecture for highly specific genome editing von Wang, Jianbin, Rebar, Edward J, Guschin, Dmitry Y, Lee, Ya-Li, Holmes, Michael C, Miller, Jeffrey C, Gregory, Philip D, Kim, Kenneth A, Waite, Adam J, Beausejour, Christian M, Wang, Nathaniel S, Pabo, Carl O, Rupniewski, Igor

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Secretion of Vascular Endothelial Growth Factor by Primary Human Fibroblasts at Senescence von Coppé, Jean-Philippe, Kauser, Katalin, Campisi, Judith, Beauséjour, Christian M.

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Highly efficient endogenous human gene correction using designed zinc-finger nucleases von Holmes, Michael C, Urnov, Fyodor D, Miller, Jeffrey C, Lee, Ya-Li, Beausejour, Christian M, Rock, Jeremy M, Augustus, Sheldon, Jamieson, Andrew C, Porteus, Matthew H, Gregory, Philip D

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Loss of the osteogenic differentiation potential during senescence is limited to bone progenitor cells and is dependent on p53 von Despars, Geneviève, Carbonneau, Cynthia L, Bardeau, Pascal, Coutu, Daniel L, Beauséjour, Christian M

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Ionizing radiation–induced expression of INK4a/ARF in murine bone marrow–derived stromal cell populations interferes with bone marrow homeostasis von Carbonneau, Cynthia L., Despars, Geneviève, Rojas-Sutterlin, Shanti, Fortin, Audrey, Le, Oanh, Hoang, Trang, Beauséjour, Christian M.

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Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation von Fumagalli, Marzia, Rossiello, Francesca, Clerici, Michela, Barozzi, Sara, Cittaro, Davide, Kaplunov, Jessica M., Bucci, Gabriele, Dobreva, Miryana, Matti, Valentina, Beausejour, Christian M., Herbig, Utz, Longhese, Maria Pia, d’Adda di Fagagna, Fabrizio

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A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen von Coppé, Jean-Philippe, Patil, Christopher K, Rodier, Francis, Krtolica, Ana, Beauséjour, Christian M, Parrinello, Simona, Hodgson, J Graeme, Chin, Koei, Desprez, Pierre-Yves, Campisi, Judith

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Therapeutic Efficacy of Cord Blood-Derived Mesenchymal Stromal Cells for the Prevention of Acute Graft-Versus-Host Disease in a Xenogenic Mouse Model von Gregoire-Gauthier, Joëlle, Selleri, Silvia, Fontaine, François, Dieng, Mame Massar, Patey, Natalie, Despars, Geneviève, Beauséjour, Christian M., Haddad, Élie

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Ageing Balancing regeneration and cancer von Beausejour, Christian M, Campisi, Judith

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Blockade of sensory abnormalities and kinin B1 receptor expression by N-Acetyl-l-Cysteine and ramipril in a rat model of insulin resistance von Ismael, Mahmoud Ali, Talbot, Sébastien, Carbonneau, Cynthia L., Beauséjour, Christian M., Couture, Réjean

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Ionizing radiation‐induced long‐term expression of senescence markers in mice is independent of p53 and immune status von Le, Oanh N. L., Rodier, Francis, Fontaine, Francois, Coppe, Jean‐Philippe, Campisi, Judith, DeGregori, James, Laverdière, Caroline, Kokta, Victor, Haddad, Elie, Beauséjour, Christian M.

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Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation von Benabdallah, Basma F, Duval, Arnaud, Rousseau, Joel, Chapdelaine, Pierre, Holmes, Michael C, Haddad, Eli, Tremblay, Jacques P, Beauséjour, Christian M

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Secretion of SDF‐1α by bone marrow‐derived stromal cells enhances skin wound healing of C57BL/6 mice exposed to ionizing radiation von Landry, Yannick, Lê, Oanh, Mace, Kimberly A., Restivo, Terry E., Beauséjour, Christian M.

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Targeted gene addition to human mesenchymal stromal cells as a cell-based plasma-soluble protein delivery platform von Benabdallah, Basma F, Allard, Emilie, Yao, Shuyuan, Friedman, Geoffrey, Gregory, Philip D, Eliopoulos, Nicoletta, Fradette, Julie, Spees, Jeffrey L, Haddad, Elie, Holmes, Michael C, Beauséjour, Christian M

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A 3D visualization tool for the design and customization of spinal braces von Fortin, D, Cheriet, F, Beauséjour, M, Debanné, P, Joncas, J, Labelle, H

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Heterotopic bone formation derived from multipotent stromal cells is not inhibited in aged mice von Carbonneau, Cynthia L, Despars, Geneviève, Moquin Beaudry, Gaël, Benabdallah, Basma, Bouhanik, Saadallah, Dépôt, Josée, Moreau, Alain, Beauséjour, Christian M

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