Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas von Puget, Stephanie, Philippe, Cathy, Bax, Dorine A, Job, Bastien, Varlet, Pascale, Junier, Marie-Pierre, Andreiuolo, Felipe, Carvalho, Dina, Reis, Ricardo, Guerrini-Rousseau, Lea, Roujeau, Thomas, Dessen, Philippe, Richon, Catherine, Lazar, Vladimir, Le Teuff, Gwenael, Sainte-Rose, Christian, Geoerger, Birgit, Vassal, Gilles, Jones, Chris, Grill, Jacques

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Integrated Molecular Genetic Profiling of Pediatric High-Grade Gliomas Reveals Key Differences With the Adult Disease von Paugh, Barbara S, Qu, Chunxu, Jones, Chris, Liu, Zhaoli, Adamowicz-Brice, Martyna, Zhang, Junyuan, Bax, Dorine A, Coyle, Beth, Barrow, Jennifer, Hargrave, Darren, Lowe, James, Gajjar, Amar, Zhao, Wei, Broniscer, Alberto, Ellison, David W, Grundy, Richard G, Baker, Suzanne J

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Novel Oncogenic PDGFRA Mutations in Pediatric High-Grade Gliomas von PAUGH, Barbara S, XIAOYAN ZHU, BRONISCER, Alberto, WETMORE, Cynthia, JINGHUI ZHANG, JONES, Chris, ELLISON, David W, BAKER, Suzanne J, CHUNXU QU, ENDERSBY, Raelene, DIAZ, Alexander K, JUNYUAN ZHANG, BAX, Dorine A, CARVALHO, Diana, REIS, Rui M, ONAR-THOMAS, Arzu

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Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN von Bjerke, Lynn, Mackay, Alan, Nandhabalan, Meera, Burford, Anna, Jury, Alexa, Popov, Sergey, Bax, Dorine A, Carvalho, Diana, Taylor, Kathryn R, Vinci, Maria, Bajrami, Ilirjana, McGonnell, Imelda M, Lord, Christopher J, Reis, Rui M, Hargrave, Darren, Ashworth, Alan, Workman, Paul, Jones, Chris

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Deletion upstream of MAB21L2 highlights the importance of evolutionarily conserved non-coding sequences for eye development von Ceroni, Fabiola, Cicekdal, Munevver B., Holt, Richard, Sorokina, Elena, Chassaing, Nicolas, Clokie, Samuel, Naert, Thomas, Talbot, Lidiya V., Muheisen, Sanaa, Bax, Dorine A., Kesim, Yesim, Kivuva, Emma C., Vincent-Delorme, Catherine, Lienkamp, Soeren S., Plaisancié, Julie, De Baere, Elfride, Calvas, Patrick, Vleminckx, Kris, Semina, Elena V., Ragge, Nicola K.

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Receptor Tyrosine Kinase Genes Amplified in Glioblastoma Exhibit a Mutual Exclusivity in Variable Proportions Reflective of Individual Tumor Heterogeneity von LITTLE, Suzanne E, POPOV, Sergey, JURY, Alexa, BAX, Dorine A, DOEY, Lawrence, AL-SARRAJ, Safa, JURGENSMEIER, Juliane M, JONES, Chris

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A distinct spectrum of copy number aberrations in pediatric high-grade gliomas von Bax, Dorine A., Mackay, Alan, Little, Suzanne E., Carvalho, Diana, Pereira, Marta Sofia Carvalho Ribeiro Viana, Tamber, Narinder, Grigoriadis, Anita E., Ashworth, Alan, Reis, R. M., Ellison, David W., Al-Sarraj, Safa, Hargrave, Darren, Jones, Chris

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Endosialin (CD248) is a marker of tumor-associated pericytes in high-grade glioma von Simonavicius, Nicole, Robertson, David, Bax, Dorine A, Jones, Chris, Huijbers, Ivo J, Isacke, Clare M

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Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development von Bax, Dorine A, Little, Suzanne E, Gaspar, Nathalie, Perryman, Lara, Marshall, Lynley, Viana-Pereira, Marta, Jones, Tania A, Williams, Richard D, Grigoriadis, Anita, Vassal, Gilles, Workman, Paul, Sheer, Denise, Reis, Rui M, Pearson, Andrew D J, Hargrave, Darren, Jones, Chris

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EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines von Bax, Dorine A., Gaspar, Nathalie, Little, Suzanne E., Marshall, Lynley, Perryman, Lara, Regairaz, Marie, Pereira, Marta Sofia Carvalho Ribeiro Viana, Vuononvirta, Raisa, Sharp, Swee Y., Reis, R. M.

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Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation von Viana-Pereira, Marta, Lee, Alicia, Popov, Sergey, Bax, Dorine A, Al-Sarraj, Safa, Bridges, Leslie R, Stávale, João N, Hargrave, Darren, Jones, Chris, Reis, Rui M

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Clinical and genetic analysis further delineates the phenotypic spectrum of ALDH1A3-related anophthalmia and microphthalmia von Kesim, Yesim, Ceroni, Fabiola, Damián, Alejandra, Blanco-Kelly, Fiona, Ayuso, Carmen, Williamson, Kathy, Paquis-Flucklinger, Véronique, Bax, Dorine A, Plaisancié, Julie, Rieubland, Claudine, Chamlal, Mostafa, Cortón, Marta, Chassaing, Nicolas, Calvas, Patrick, Ragge, Nicola K

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Analysis of Fibroblast Growth Factor 14 (FGF14) structural variants reveals the genetic basis of the early onset nystagmus locus NYS4 and variable ataxia von Ceroni, Fabiola, Osborne, Daniel, Clokie, Samuel, Bax, Dorine A, Cassidy, Emma J, Dunn, Matt J, Harris, Christopher M, Self, Jay E, Ragge, Nicola K

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Multifaceted Dysregulation of the Epidermal Growth Factor Receptor Pathway in Clear Cell Sarcoma of the Kidney von LITTLE, Suzanne E, BAX, Dorine A, RODRIGUEZ-PINILLA, Maria, NATRAJAN, Rachael, MESSAHEL, Boo, PRITCHARD-JONES, Kathy, VUJANIC, Gordan M, REIS, Jorge S, JONES, Chris

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MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature von Gaspar, Nathalie, Marshall, Lynley, Perryman, Lara, Bax, Dorine A., Little, Suzanne E., Pereira, Marta Sofia Carvalho Ribeiro Viana, Sharp, Swee Y., Vassal, Gilles, Pearson, Andrew D. J., Reis, R. M., Hargrave, Darren, Workman, Paul, Jones, Chris

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De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies von Holt, Richard J., Young, Rodrigo M., Crespo, Berta, Ceroni, Fabiola, Curry, Cynthia J., Bellacchio, Emanuele, Bax, Dorine A., Ciolfi, Andrea, Simon, Marleen, Fagerberg, Christina R., van Binsbergen, Ellen, De Luca, Alessandro, Memo, Luigi, Dobyns, William B., Mohammed, Alaa Afif, Clokie, Samuel J.H., Zazo Seco, Celia, Jiang, Yong-Hui, Sørensen, Kristina P., Andersen, Helle, Sullivan, Jennifer, Powis, Zöe, Chassevent, Anna, Smith-Hicks, Constance, Petrovski, Slavé, Antoniadi, Thalia, Shashi, Vandana, Gelb, Bruce D., Wilson, Stephen W., Gerrelli, Dianne, Tartaglia, Marco, Chassaing, Nicolas, Calvas, Patrick, Ragge, Nicola K.

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Role of the rdxA and frxA genes in oxygen-dependent metronidazole resistance of Helicobacter pylori von Gerrits, Monique M, van der Wouden, Egbert-Jan, Bax, Dorine A, van Zwet, Anton A, van Vliet, Arnoud HM, de Jong, Albertine, Kusters, Johannes G, Thijs, Jaap C, Kuipers, Ernst J

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De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies von Holt, Richard J., Young, Rodrigo M., Crespo, Berta, Ceroni, Fabiola, Curry, Cynthia J., Bellacchio, Emanuele, Bax, Dorine A., Ciolfi, Andrea, Simon, Marleen, Fagerberg, Christina R., van Binsbergen, Ellen, De Luca, Alessandro, Memo, Luigi, Dobyns, William B., Mohammed, Alaa Afif, Clokie, Samuel J.H., Zazo Seco, Celia, Jiang, Yong-Hui, Sørensen, Kristina P., Andersen, Helle, Sullivan, Jennifer, Powis, Zöe, Chassevent, Anna, Smith-Hicks, Constance, Petrovski, Slavé, Antoniadi, Thalia, Shashi, Vandana, Gelb, Bruce D., Wilson, Stephen W., Gerrelli, Dianne, Tartaglia, Marco, Chassaing, Nicolas, Calvas, Patrick, Ragge, Nicola K.

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Deletion upstream of MAB21L2 highlights the importance of evolutionarily conserved non-coding sequences for eye development von Ceroni, Fabiola, Cicekdal, Munevver B, Holt, Richard, Sorokina, Elena, Chassaing, Nicolas, Clokie, Samuel, Naert, Thomas, Talbot, Lidiya V, Muheisen, Sanaa, Bax, Dorine A, Kesim, Yesim, Kivuva, Emma C, Vincent-Delorme, Catherine, Lienkamp, Soeren S, Plaisancié, Julie, De Baere, Elfride, Calvas, Patrick, Vleminckx, Kris, Semina, Elena V, Ragge, Nicola K

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Correction: Clinical and genetic analysis further delineates the phenotypic spectrum of ALDH1A3-related anophthalmia and microphthalmia von Kesim, Yesim, Ceroni, Fabiola, Damián, Alejandra, Blanco-Kelly, Fiona, Ayuso, Carmen, Williamson, Kathy, Paquis-Flucklinger, Véronique, Bax, Dorine A, Plaisancié, Julie, Rieubland, Claudine, Chamlal, Mostafa, Cortón, Marta, Chassaing, Nicolas, Calvas, Patrick, Ragge, Nicola K

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