NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR von Yoshino, Jun, Baur, Joseph A., Imai, Shin-ichiro

Volltext

Therapeutic potential of resveratrol: the in vivo evidence von Sinclair, David A, Baur, Joseph A

Volltext

Rapalogs and mTOR inhibitors as anti-aging therapeutics von Lamming, Dudley W, Ye, Lan, Sabatini, David M, Baur, Joseph A

Volltext

NAD+ metabolism governs the proinflammatory senescence-associated secretome von Nacarelli, Timothy, Lau, Lena, Fukumoto, Takeshi, Zundell, Joseph, Fatkhutdinov, Nail, Wu, Shuai, Aird, Katherine M., Iwasaki, Osamu, Kossenkov, Andrew V., Schultz, David, Noma, Ken-ichi, Baur, Joseph A., Schug, Zachary, Tang, Hsin-Yao, Speicher, David W., David, Gregory, Zhang, Rugang

Volltext

Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns von Bhasin, Shalender, Seals, Douglas, Migaud, Marie, Musi, Nicolas, Baur, Joseph A

Volltext

What is new for an old molecule? Systematic review and recommendations on the use of resveratrol von Vang, Ole, Ahmad, Nihal, Baile, Clifton A, Baur, Joseph A, Brown, Karen, Csiszar, Anna, Das, Dipak K, Delmas, Dominique, Gottfried, Carmem, Lin, Hung-Yun, Ma, Qing-Yong, Mukhopadhyay, Partha, Nalini, Namasivayam, Pezzuto, John M, Richard, Tristan, Shukla, Yogeshwer, Surh, Young-Joon, Szekeres, Thomas, Szkudelski, Tomasz, Walle, Thomas, Wu, Joseph M

Volltext

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance von Jang, Cholsoon, Oh, Sungwhan F, Wada, Shogo, Rowe, Glenn C, Liu, Laura, Chan, Mun Chun, Rhee, James, Hoshino, Atsushi, Kim, Boa, Ibrahim, Ayon, Baca, Luisa G, Kim, Esl, Ghosh, Chandra C, Parikh, Samir M, Jiang, Aihua, Chu, Qingwei, Forman, Daniel E, Lecker, Stewart H, Krishnaiah, Saikumari, Rabinowitz, Joshua D, Weljie, Aalim M, Baur, Joseph A, Kasper, Dennis L, Arany, Zoltan

Volltext

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity von LAMMING, Dudley W, LAN YE, GUERTIN, David A, SABATINI, David M, BAUR, Joseph A, KATAJISTO, Pekka, GONCALVES, Marcus D, SAITOH, Maki, STEVENS, Deanna M, DAVIS, James G, SALMON, Adam B, RICHARDSON, Arlan, AHIMA, Rexford S

Volltext

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mic... von Tarantini, Stefano, Valcarcel-Ares, Marta Noa, Toth, Peter, Yabluchanskiy, Andriy, Tucsek, Zsuzsanna, Kiss, Tamas, Hertelendy, Peter, Kinter, Michael, Ballabh, Praveen, Süle, Zoltán, Farkas, Eszter, Baur, Joseph A, Sinclair, David A, Csiszar, Anna, Ungvari, Zoltan

Volltext

A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate von Wang, Wenshan, Ishibashi, Jeff, Trefely, Sophie, Shao, Mengle, Cowan, Alexis J., Sakers, Alexander, Lim, Hee-Woong, O’Connor, Sean, Doan, Mary T., Cohen, Paul, Baur, Joseph A., King, M. Todd, Veech, Richard L., Won, Kyoung-Jae, Rabinowitz, Joshua D., Snyder, Nathaniel W., Gupta, Rana K., Seale, Patrick

Volltext

Resveratrol Prevents High Fat/Sucrose Diet-Induced Central Arterial Wall Inflammation and Stiffening in Nonhuman Primates von Mattison, Julie A., Wang, Mingyi, Bernier, Michel, Zhang, Jing, Park, Sung-Soo, Maudsley, Stuart, An, Steven S., Santhanam, Lakshmi, Martin, Bronwen, Faulkner, Shakeela, Morrell, Christopher, Baur, Joseph A., Peshkin, Leonid, Sosnowska, Danuta, Csiszar, Anna, Herbert, Richard L., Tilmont, Edward M., Ungvari, Zoltan, Pearson, Kevin J., Lakatta, Edward G., de Cabo, Rafael

Volltext

Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration von Mukherjee, Sarmistha, Chellappa, Karthikeyani, Moffitt, Andrea, Ndungu, Joan, Dellinger, Ryan W., Davis, James G., Agarwal, Beamon, Baur, Joseph A.

Volltext

Rapamycin Blocks Induction of the Thermogenic Program in White Adipose Tissue von Tran, Cassie M, Mukherjee, Sarmistha, Ye, Lan, Frederick, David W, Kissig, Megan, Davis, James G, Lamming, Dudley W, Seale, Patrick, Baur, Joseph A

Volltext

Single‐Voxel 1H MR spectroscopy of cerebral nicotinamide adenine dinucleotide (NAD+) in humans at 7T using a 32‐channel volume coil von Bagga, Puneet, Hariharan, Hari, Wilson, Neil E., Beer, Joanne C., Shinohara, Russell T., Elliott, Mark A., Baur, Joseph A., Marincola, Francesco M., Witschey, Walter R., Haris, Mohammad, Detre, John A., Reddy, Ravinder

Volltext

Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes von Chandramouleeswaran, Prasanna M., Guha, Manti, Shimonosono, Masataka, Whelan, Kelly A., Maekawa, Hisatsugu, Sachdeva, Uma M., Ruthel, Gordon, Mukherjee, Sarmistha, Engel, Noah, Gonzalez, Michael, Garifallou, James, Ohashi, Shinya, Klein-Szanto, Andres J., Mesaros, Clementina A., Blair, Ian A., da Silva, Renata Pellegrino, Hakonarson, Hakon, Noguchi, Eishi, Baur, Joseph A., Nakagawa, Hiroshi

Volltext

Hypothalamic mTORC2 is essential for metabolic health and longevity von Chellappa, Karthikeyani, Brinkman, Jacqueline A., Mukherjee, Sarmistha, Morrison, Mark, Alotaibi, Mohammed I., Carbajal, Kathryn A., Alhadeff, Amber L., Perron, Isaac J., Yao, Rebecca, Purdy, Cole S., DeFelice, Denise M., Wakai, Matthew H., Tomasiewicz, Jay, Lin, Amy, Meyer, Emma, Peng, Yajing, Arriola Apelo, Sebastian I., Puglielli, Luigi, Betley, J. Nicholas, Paschos, Georgios K., Baur, Joseph A., Lamming, Dudley W.

Volltext

NAD+ flux is maintained in aged mice despite lower tissue concentrations von McReynolds, Melanie R., Chellappa, Karthikeyani, Chiles, Eric, Jankowski, Connor, Shen, Yihui, Chen, Li, Descamps, Hélène C., Mukherjee, Sarmistha, Bhat, Yashaswini R., Lingala, Siddharth R., Chu, Qingwei, Botolin, Paul, Hayat, Faisal, Doke, Tomohito, Susztak, Katalin, Thaiss, Christoph A., Lu, Wenyun, Migaud, Marie E., Su, Xiaoyang, Rabinowitz, Joshua D., Baur, Joseph A.

Volltext

Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism von Nunn, Elizabeth, Jaiswal, Natasha, Gavin, Matthew, Uehara, Kahealani, Stefkovich, Megan, Drareni, Karima, Calhoun, Ryan, Lee, Michelle, Holman, Corey D., Baur, Joseph A., Seale, Patrick, Titchenell, Paul M.

Volltext

Supplemental arginine vasopressin during the resuscitation of severe hemorrhagic shock preserves renal mitochondrial function von Sims, Carrie A, Yuxia, Guan, Singh, Khushboo, Werlin, Evan C, Reilly, Patrick M, Baur, Joseph A

Volltext

Age-related NAD+ decline von McReynolds, Melanie R., Chellappa, Karthikeyani, Baur, Joseph A.

Volltext