A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design von Beno, Brett R, Yeung, Kap-Sun, Bartberger, Michael D, Pennington, Lewis D, Meanwell, Nicholas A

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Recent advances in the development of acetyl-CoA carboxylase (ACC) inhibitors for the treatment of metabolic disease von Bourbeau, Matthew P, Bartberger, Michael D

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Systematic Study of the Glutathione Reactivity of N‑Phenylacrylamides: 2. Effects of Acrylamide Substitution von Birkholz, Adam, Kopecky, David J, Volak, Laurie P, Bartberger, Michael D, Chen, Yuping, Tegley, Christopher M, Arvedson, Tara, McCarter, John D, Fotsch, Christopher, Cee, Victor J

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Discovery of TRPM8 Antagonist (S)‑6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment o... von Horne, Daniel B, Biswas, Kaustav, Brown, James, Bartberger, Michael D, Clarine, Jeffrey, Davis, Carl D, Gore, Vijay K, Harried, Scott, Horner, Michelle, Kaller, Matthew R, Lehto, Sonya G, Liu, Qingyian, Ma, Vu V, Monenschein, Holger, Nguyen, Thomas T, Yuan, Chester C, Youngblood, Beth D, Zhang, Maosheng, Zhong, Wenge, Allen, Jennifer R, Chen, Jian Jeffrey, Gavva, Narender R

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Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction von Rew, Yosup, Sun, Daqing, Gonzalez-Lopez De Turiso, Felix, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Deignan, Jeffrey, Fox, Brian M, Gustin, Darin, Huang, Xin, Jiang, Min, Jiao, Xianyun, Jin, Lixia, Kayser, Frank, Kopecky, David J, Li, Yihong, Lo, Mei-Chu, Long, Alexander M, Michelsen, Klaus, Oliner, Jonathan D, Osgood, Tao, Ragains, Mark, Saiki, Anne Y, Schneider, Steve, Toteva, Maria, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Medina, Julio C, Olson, Steven H

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From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) von Cheng, Yuan, Judd, Ted C, Bartberger, Michael D, Brown, James, Chen, Kui, Fremeau, Robert T, Hickman, Dean, Hitchcock, Stephen A, Jordan, Brad, Li, Vivian, Lopez, Patricia, Louie, Steven W, Luo, Yi, Michelsen, Klaus, Nixey, Thomas, Powers, Timothy S, Rattan, Claire, Sickmier, E. Allen, St. Jean, David J, Wahl, Robert C, Wen, Paul H, Wood, Stephen

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Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors von Lloyd, David J., St Jean, David J., Kurzeja, Robert J. M., Wahl, Robert C., Michelsen, Klaus, Cupples, Rod, Chen, Michelle, Wu, John, Sivits, Glenn, Helmering, Joan, Komorowski, Renée, Ashton, Kate S., Pennington, Lewis D., Fotsch, Christopher, Vazir, Mukta, Chen, Kui, Chmait, Samer, Zhang, Jiandong, Liu, Longbin, Norman, Mark H., Andrews, Kristin L., Bartberger, Michael D., Van, Gwyneth, Galbreath, Elizabeth J., Vonderfecht, Steven L., Wang, Minghan, Jordan, Steven R., Véniant, Murielle M., Hale, Clarence

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Selective and Potent Morpholinone Inhibitors of the MDM2–p53 Protein–Protein Interaction von Gonzalez, Ana Z, Eksterowicz, John, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Duquette, Jason, Fox, Brian M, Fu, Jiasheng, Huang, Xin, Houze, Jonathan B, Jin, Lixia, Li, Yihong, Li, Zhihong, Ling, Yun, Lo, Mei-Chu, Long, Alexander M, McGee, Lawrence R, McIntosh, Joel, McMinn, Dustin L, Oliner, Jonathan D, Osgood, Tao, Rew, Yosup, Saiki, Anne Y, Shaffer, Paul, Wortman, Sarah, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Olson, Steven H, Medina, Julio C, Sun, Daqing

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Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors von Gonzalez-Lopez de Turiso, Felix, Sun, Daqing, Rew, Yosup, Bartberger, Michael D, Beck, Hilary P, Canon, Jude, Chen, Ada, Chow, David, Correll, Tiffany L, Huang, Xin, Julian, Lisa D, Kayser, Frank, Lo, Mei-Chu, Long, Alexander M, McMinn, Dustin, Oliner, Jonathan D, Osgood, Tao, Powers, Jay P, Saiki, Anne Y, Schneider, Steve, Shaffer, Paul, Xiao, Shou-Hua, Yakowec, Peter, Yan, Xuelei, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Medina, Julio C, Olson, Steven H

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An Efficient, Regioselective Amination of 3,5-Disubstituted Pyridine N‑Oxides Using Saccharin as an Ammonium Surrogate von Farrell, Robert P, Silva Elipe, Maria Victoria, Bartberger, Michael D, Tedrow, Jason S, Vounatsos, Filisaty

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A Biochemical Rationale for the Discrete Behavior of Nitroxyl and Nitric Oxide in the Cardiovascular System von Miranda, Katrina M., Paolocci, Nazareno, Katori, Tatsuo, Thomas, Douglas D., Ford, Eleonora, Bartberger, Michael D., Espey, Michael G., Kass, David A., Feelisch, Martin, Fukuto, Jon M., Wink, David A.

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The Reduction Potential of Nitric Oxide (NO) and Its Importance to NO Biochemistry von Bartberger, Michael D., Liu, Wei, Ford, Eleonora, Miranda, Katrina M., Switzer, Christopher, Fukuto, Jon M., Farmer, Patrick J., Wink, David A., Houk, Kendall N.

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The Physiological Chemistry and Biological Activity of Nitroxyl (HNO):  The Neglected, Misunderstood, and Enigmatic Nitrogen Oxide von Fukuto, Jon M, Bartberger, Michael D, Dutton, Andrew S, Paolocci, Nazareno, Wink, David A, Houk, K. N

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Synthesis and structure–activity relationship of trisubstituted thiazoles as Cdc7 kinase inhibitors von Reichelt, Andreas, Bailis, Julie M., Bartberger, Michael D., Yao, Guomin, Shu, Hong, Kaller, Matthew R., Allen, John G., Weidner, Margaret F., Keegan, Kathleen S., Dao, Jennifer H.

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Ir-Catalyzed Asymmetric Allylic Alkylation of Dialkyl Malonates Enabling the Construction of Enantioenriched All-Carbon Quaternary Centers von Moghadam, Farbod A., Hicks, Elliot F., Sercel, Zachary P., Cusumano, Alexander Q., Bartberger, Michael D., Stoltz, Brian M.

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Enantioselective synthesis of highly oxygenated acyclic quaternary center-containing building blocks via palladium-catalyzed decarboxylative allylic alkylation of cyclic siloxyketo... von Ngamnithiporn, Aurapat, Iwayama, Toshihiko, Bartberger, Michael D, Stoltz, Brian M

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Insertion of Helium and Molecular Hydrogen Through the Orifice of an Open Fullerene von Rubin, Yves, Jarrosson, Thibaut, Wang, Guan-Wu, Bartberger, Michael D., Houk, K. N., Schick, Georg, Saunders, Martin, Cross, R. James

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Systematic Study of the Glutathione (GSH) Reactivity of N‑Arylacrylamides: 1. Effects of Aryl Substitution von Cee, Victor J, Volak, Laurie P, Chen, Yuping, Bartberger, Michael D, Tegley, Chris, Arvedson, Tara, McCarter, John, Tasker, Andrew S, Fotsch, Christopher

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Discovery and Optimization of Potent GPR40 Full Agonists Containing Tricyclic Spirocycles von Wang, Yingcai, Liu, Jiwen (Jim), Dransfield, Paul J, Zhu, Liusheng, Wang, Zhongyu, Du, Xiaohui, Jiao, Xianyun, Su, Yongli, Li, An-rong, Brown, Sean P, Kasparian, Annie, Vimolratana, Marc, Yu, Ming, Pattaropong, Vatee, Houze, Jonathan B, Swaminath, Gayathri, Tran, Thanhvien, Nguyen, Khanh, Guo, Qi, Zhang, Jane, Zhuang, Run, Li, Frank, Miao, Lynn, Bartberger, Michael D, Correll, Tiffany L, Chow, David, Wong, Simon, Luo, Jian, Lin, Daniel C.-H, Medina, Julio C

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On the Acidity and Reactivity of HNO in Aqueous Solution and Biological Systems von Bartberger, Michael D., Fukuto, Jon M., Houk, K. N.

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