Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation von Goult, Benjamin T, Bouaouina, Mohamed, Elliott, Paul R, Bate, Neil, Patel, Bipin, Gingras, Alexandre R, Grossmann, J Günter, Roberts, Gordon C K, Calderwood, David A, Critchley, David R, Barsukov, Igor L

Volltext

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras von Lilja, Johanna, Zacharchenko, Thomas, Georgiadou, Maria, Jacquemet, Guillaume, Franceschi, Nicola De, Peuhu, Emilia, Hamidi, Hellyeh, Pouwels, Jeroen, Martens, Victoria, Nia, Fatemeh Hassani, Beifuss, Malte, Boeckers, Tobias, Kreienkamp, Hans-Juergen, Barsukov, Igor L., Ivaska, Johanna

Volltext

LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex von Zacharchenko, Thomas, Qian, Xiaolan, Goult, Benjamin T., Jethwa, Devina, Almeida, Teresa B., Ballestrem, Christoph, Critchley, David R., Lowy, Douglas R., Barsukov, Igor L.

Volltext

RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover von Goult, Benjamin T., Zacharchenko, Thomas, Bate, Neil, Tsang, Ricky, Hey, Fiona, Gingras, Alexandre R., Elliott, Paul R., Roberts, Gordon C.K., Ballestrem, Christoph, Critchley, David R., Barsukov, Igor L.

Volltext

SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers von Lilja, Johanna, Kaivola, Jasmin, Conway, James R. W., Vuorio, Joni, Parkkola, Hanna, Roivas, Pekka, Dibus, Michal, Chastney, Megan R., Varila, Taru, Jacquemet, Guillaume, Peuhu, Emilia, Wang, Emily, Pentikäinen, Ulla, Martinez D. Posada, Itziar, Hamidi, Hellyeh, Najumudeen, Arafath K., Sansom, Owen J., Barsukov, Igor L., Abankwa, Daniel, Vattulainen, Ilpo, Salmi, Marko, Ivaska, Johanna

Volltext

Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: Implications for talin activation von Goult, Benjamin T., Xu, Xiao-Ping, Gingras, Alexandre R., Swift, Mark, Patel, Bipin, Bate, Neil, Kopp, Petra M., Barsukov, Igor L., Critchley, David R., Volkmann, Niels, Hanein, Dorit

Volltext

The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain von Elliott, Paul R., Goult, Benjamin T., Kopp, Petra M., Bate, Neil, Grossmann, J. Günter, Roberts, Gordon C.K., Critchley, David R., Barsukov, Igor L.

Volltext

The structure of the C-terminal actin-binding domain of talin von Gingras, Alexandre R, Bate, Neil, Goult, Benjamin T, Hazelwood, Larnele, Canestrelli, Ilona, Grossmann, J Günter, Liu, HongJun, Putz, Nicholas S M, Roberts, Gordon C K, Volkmann, Niels, Hanein, Dorit, Barsukov, Igor L, Critchley, David R

Volltext

The Structure of an Interdomain Complex That Regulates Talin Activity von Goult, Benjamin T., Bate, Neil, Anthis, Nicholas J., Wegener, Kate L., Gingras, Alexandre R., Patel, Bipin, Barsukov, Igor L., Campbell, Iain D., Roberts, Gordon C.K., Critchley, David R.

Volltext

Mapping and Consensus Sequence Identification for Multiple Vinculin Binding Sites within the Talin Rod von Gingras, Alexandre R., Ziegler, Wolfgang H., Frank, Ronald, Barsukov, Igor L., Roberts, Gordon C.K., Critchley, David R., Emsley, Jonas

Volltext

Asymmetric Mode of Ca2+-S100A4 Interaction with Nonmuscle Myosin IIA Generates Nanomolar Affinity Required for Filament Remodeling von Elliott, Paul R., Irvine, Andrew F., Jung, Hyun Suk, Tozawa, Kaeko, Pastok, Martyna W., Picone, Remigio, Badyal, Sandip K., Basran, Jaswir, Rudland, Philip S., Barraclough, Roger, Lian, Lu-Yun, Bagshaw, Clive R., Kriajevska, Marina, Barsukov, Igor L.

Volltext

Role of vinculin in regulating focal adhesion turnover von Saunders, Ruth M., Holt, Mark R., Jennings, Lisa, Sutton, Deborah H., Barsukov, Igor L., Bobkov, Andrey, Liddington, Robert C., Adamson, Eileen A., Dunn, Graham A., Critchley, David R.

Volltext

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle von Papagrigoriou, Evangelos, Gingras, Alexandre R, Barsukov, Igor L, Bate, Neil, Fillingham, Ian J, Patel, Bipin, Frank, Ronald, Ziegler, Wolfgang H, Roberts, Gordon CK, Critchley, David R, Emsley, Jonas

Volltext

Structural Determinants of Integrin Binding to the Talin Rod von Gingras, Alexandre R., Ziegler, Wolfgang H., Bobkov, Andrey A., Joyce, M.Gordon, Fasci, Domenico, Himmel, Mirko, Rothemund, Sven, Ritter, Anett, Grossmann, J.Günter, Patel, Bipin, Bate, Neil, Goult, Benjamin T., Emsley, Jonas, Barsukov, Igor L., Roberts, Gordon C.K., Liddington, Robert C., Ginsberg, Mark H., Critchley, David R.

Volltext

Vinculin controls talin engagement with the actomyosin machinery von Atherton, Paul, Stutchbury, Ben, Wang, De-Yao, Jethwa, Devina, Tsang, Ricky, Meiler-Rodriguez, Eugenia, Wang, Pengbo, Bate, Neil, Zent, Roy, Barsukov, Igor L., Goult, Benjamin T., Critchley, David R., Ballestrem, Christoph

Volltext

Structural Basis for the Interaction between the Cytoplasmic Domain of the Hyaluronate Receptor Layilin and the Talin F3 Subdomain von Wegener, Kate L., Basran, Jaswir, Bagshaw, Clive R., Campbell, Iain D., Roberts, Gordon C.K., Critchley, David R., Barsukov, Igor L.

Volltext

Direct interaction of metastasis-inducing S100P protein with tubulin causes enhanced cell migration without changes in cell adhesion von Du, Min, Wang, Guozheng, Barsukov, Igor L, Gross, Stephane R, Smith, Richard, Rudland, Philip S

Volltext

Pressure-Dependent Chemical Shifts in the R3 Domain of Talin Show that It Is Thermodynamically Poised for Binding to Either Vinculin or RIAM von Baxter, Nicola J., Zacharchenko, Thomas, Barsukov, Igor L., Williamson, Mike P.

Volltext

The domain structure of talin: Residues 1815–1973 form a five-helix bundle containing a cryptic vinculin-binding site von Goult, Benjamin T., Gingras, Alexandre R., Bate, Neil, Barsukov, Igor L., Critchley, David R., Roberts, Gordon C.K.

Volltext

Anion binding to a cationic europium(III) probe enables the first real-time assay of heparan sulfotransferase activity von Wheeler, Simon, Breen, Colum, Li, Yong, Hewitt, Sarah H, Robertson, Erin, Yates, Edwin A, Barsukov, Igor L, Fernig, David G, Butler, Stephen J

Volltext