Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer von Whatcott, Clifford J, Ng, Serina, Barrett, Michael T, Hostetter, Galen, Von Hoff, Daniel D, Han, Haiyong

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Single nucleus DNA sequencing of flow sorted archived frozen and formalin fixed paraffin embedded solid tumors von Zhou, Yumei, Chen, Xianfeng, Chapman, Jocelyn S, Barrett, Michael T

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Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas von Lenkiewicz, Elizabeth, Malasi, Smriti, Hogenson, Tara L, Flores, Luis F, Barham, Whitney, Phillips, William J, Roesler, Alexander S, Chambers, Kendall R, Rajbhandari, Nirakar, Hayashi, Akimasa, Antal, Corina E, Downes, Michael, Grandgenett, Paul M, Hollingsworth, Michael A, Cridebring, Derek, Xiong, Yuning, Lee, Jeong-Heon, Ye, Zhenqing, Yan, Huihuang, Hernandez, Matthew C, Leiting, Jennifer L, Evans, Ronald M, Ordog, Tamas, Truty, Mark J, Borad, Mitesh J, Reya, Tannishtha, Von Hoff, Daniel D, Fernandez-Zapico, Martin E, Barrett, Michael T

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Genomic landscape of diploid and aneuploid microsatellite stable early onset colorectal cancer von Zhou, Yumei, Chen, Xianfeng, Chen, Jun, Kendrick, Conner D., Ramanathan, Ramesh K., Graham, Rondell P., Kossick, Kimberlee F., Boardman, Lisa A., Barrett, Michael T.

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The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers von Barrett, Michael T, Lenkiewicz, Elizabeth, Malasi, Smriti, Basu, Anamika, Yearley, Jennifer Holmes, Annamalai, Lakshmanan, McCullough, Ann E, Kosiorek, Heidi E, Narang, Pooja, Wilson Sayres, Melissa A, Chen, Meixuan, Anderson, Karen S, Pockaj, Barbara A

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Clonal analyses of refractory testicular germ cell tumors von Barrett, Michael T, Lenkiewicz, Elzbieta, Malasi, Smriti, Stanton, Melissa, Slack, James, Andrews, Paul, Pagliaro, Lance, Bryce, Alan H

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JAK2 and PD-L1 Amplification Enhance the Dynamic Expression of PD-L1 in Triple-negative Breast Cancer von Chen, Meixuan, Pockaj, Barbara, Andreozzi, Mariacarla, Barrett, Michael T., Krishna, Sri, Eaton, Seron, Niu, Ruifang, Anderson, Karen S.

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Genomic amplification of 9p24.1 targeting JAK2, PD-L1, and PD-L2 is enriched in high-risk triple negative breast cancer von Barrett, Michael T, Anderson, Karen S, Lenkiewicz, Elizabeth, Andreozzi, Mariacarla, Cunliffe, Heather E, Klassen, Christine L, Dueck, Amylou C, McCullough, Ann E, Reddy, Srikanth K, Ramanathan, Ramesh K, Northfelt, Donald W, Pockaj, Barbara A

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Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein von Wang, Yu, Ding, Xiwei, Wang, Shaoqing, Moser, Catherine D, Shaleh, Hassan M, Mohamed, Essa A, Chaiteerakij, Roongruedee, Allotey, Loretta K, Chen, Gang, Miyabe, Katsuyuki, McNulty, Melissa S, Ndzengue, Albert, Knudson, Ryan A, Greipp, Patricia T, Clark, Karl J, Torbenson, Michael S, Kipp, Benjamin R, Zhou, Jie, Barrett, Michael T, Gustafson, Michael P, Alberts, Steven R, Borad, Mitesh J, Roberts, Lewis R

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A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer von Antal, Corina E., Oh, Tae Gyu, Aigner, Stefan, Luo, En-Ching, Yee, Brian A., Campos, Tania, Tiriac, Hervé, Rothamel, Katherine L., Cheng, Zhang, Jiao, Henry, Wang, Allen, Hah, Nasun, Lenkiewicz, Elizabeth, Lumibao, Jan C., Truitt, Morgan L., Estepa, Gabriela, Banayo, Ester, Bashi, Senada, Esparza, Edgar, Munoz, Ruben M., Diedrich, Jolene K., Sodir, Nicole M., Mueller, Jasmine R., Fraser, Cory R., Borazanci, Erkut, Propper, David, Von Hoff, Daniel D., Liddle, Christopher, Yu, Ruth T., Atkins, Annette R., Han, Haiyong, Lowy, Andrew M., Barrett, Michael T., Engle, Dannielle D., Evan, Gerard I., Yeo, Gene W., Downes, Michael, Evans, Ronald M.

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Advancing a clinically relevant perspective of the clonal nature of cancer von Ruiz, Christian, Lenkiewicz, Elizabeth, Evers, Lisa, Holley, Tara, Robeson, Alex, Kiefer, Jeffrey, Demeure, Michael J, Hollingsworth, Michael A, Shen, Michael, Prunkard, Donna, Rabinovitch, Peter S, Zellweger, Tobias, Mousses, Spyro, Trent, Jeffrey M, Carpten, John D, Bubendorf, Lukas, Von Hoff, Daniel, Barrett, Michael T

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PDJ amplicon in triple negative breast cancer von Roesler, Alexander S., Malasi, Smriti, Koslosky, Lori, Hartmayer, Peter, Naab, Tammey J., Carter, Jodi M., Zahrieh, David, Hillman, David, Leon-Ferre, Roberto A., Couch, Fergus J., Goetz, Matthew P., Anderson, Karen S., Pockaj, Barbara A., Barrett, Michael T.

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Chromosome-breakage genomic instability and chromothripsis in breast cancer von Przybytkowski, Ewa, Lenkiewicz, Elizabeth, Barrett, Michael T, Klein, Kathleen, Nabavi, Sheida, Greenwood, Celia M T, Basik, Mark

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Clinical study of genomic drivers in pancreatic ductal adenocarcinoma von Barrett, Michael T, Deiotte, Ray, Lenkiewicz, Elizabeth, Malasi, Smriti, Holley, Tara, Evers, Lisa, Posner, Richard G, Jones, Timothy, Han, Haiyong, Sausen, Mark, Velculescu, Victor E, Drebin, Jeffrey, O'Dwyer, Peter, Jameson, Gayle, Ramanathan, Ramesh K, Von Hoff, Daniel D

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Unique evolutionary trajectories of breast cancers with distinct genomic and spatial heterogeneity von Phung, Tanya N., Webster, Timothy H., Lenkiewicz, Elizabeth, Malasi, Smriti, Andreozzi, Mariacarla, McCullough, Ann E., Anderson, Karen S., Pockaj, Barbara A., Wilson, Melissa A., Barrett, Michael T.

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Delineation of human prostate cancer evolution identifies chromothripsis as a polyclonal event and FKBP4 as a potential driver of castration resistance von Federer‐Gsponer, Joël R, Quintavalle, Cristina, Müller, David C, Dietsche, Tanja, Perrina, Valeria, Lorber, Thomas, Juskevicius, Darius, Lenkiewicz, Elisabeth, Zellweger, Tobias, Gasser, Thomas, Barrett, Michael T, Rentsch, Cyrill A, Bubendorf, Lukas, Ruiz, Christian

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Deep clonal profiling of formalin fixed paraffin embedded clinical samples von Holley, Tara, Lenkiewicz, Elizabeth, Evers, Lisa, Tembe, Waibhav, Ruiz, Christian, Gsponer, Joel R, Rentsch, Cyrill A, Bubendorf, Lukas, Stapleton, Mark, Amorese, Doug, Legendre, Christophe, Cunliffe, Heather E, McCullough, Ann E, Pockaj, Barbara, Craig, David, Carpten, John, Von Hoff, Daniel, Iacobuzio-Donahue, Christine, Barrett, Michael T

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Comparative Genomic Hybridization Using Oligonucleotide Microarrays and Total Genomic DNA von Barrett, Michael T., Scheffer, Alicia, Ben-Dor, Amir, Sampas, Nick, Lipson, Doron, Kincaid, Robert, Tsang, Peter, Curry, Bo, Baird, Kristin, Meltzer, Paul S., Yakhini, Zohar, Bruhn, Laurakay, Laderman, Stephen, Caruthers, Marvin H.

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A phase 2 study of vorinostat in locally advanced, recurrent, or metastatic adenoid cystic carcinoma von Goncalves, Priscila H, Heilbrun, Lance K, Barrett, Michael T, Kummar, Shivaani, Hansen, Aaron R, Siu, Lillian L, Piekarz, Richard L, Sukari, Ammar W, Chao, Joseph, Pilat, Mary Jo, Smith, Daryn W, Casetta, Lindsay, Boerner, Scott A, Chen, Alice, Lenkiewicz, Elizabeth, Malasi, Smriti, LoRusso, Patricia M

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Phase II clinical trial of nab‐paclitaxel plus cisplatin plus gemcitabine (NABPLAGEM) in patients with untreated advanced pancreatic cancer von Jameson, Gayle S., Hosein, Peter J., Pierce, Erin, Kamgar, Mandana, Gordon, Michael S., Snyder, Courtney, Roe, Denise J., Wertheim, Betsy C., Davey, Marina, Barrett, Michael T., Von Hoff, Daniel D., Borazanci, Erkut

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