Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors von Barnett, Stanley F, Defeo-Jones, Deborah, Fu, Sheng, Hancock, Paula J, Haskell, Kathleen M, Jones, Raymond E, Kahana, Jason A, Kral, Astrid M, Leander, Karen, Lee, Ling L, Malinowski, John, McAvoy, Elizabeth M, Nahas, Debbie D, Robinson, Ronald G, Huber, Hans E

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Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors von Lindsley, Craig W., Zhao, Zhijian, Leister, William H., Robinson, Ronald G., Barnett, Stanley F., Defeo-Jones, Deborah, Jones, Raymond E., Hartman, George D., Huff, Joel R., Huber, Hans E., Duggan, Mark E.

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Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape von Bartz, René, Fan, Haihong, Zhang, Jingtao, Innocent, Nathalie, Cherrin, Craig, Beck, Stephen C, Pei, Yi, Momose, Aaron, Jadhav, Vasant, Tellers, David M, Meng, Fanyu, Crocker, Louis S, Sepp-Lorenzino, Laura, Barnett, Stanley F

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Quantitative evaluation of siRNA delivery in vivo von Pei, Yi, Hancock, Paula J, Zhang, Hangchun, Bartz, René, Cherrin, Craig, Innocent, Nathalie, Pomerantz, Colin J, Seitzer, Jessica, Koser, Martin L, Abrams, Marc T, Xu, Yan, Kuklin, Nelly A, Burke, Paul A, Sachs, Alan B, Sepp-Lorenzino, Laura, Barnett, Stanley F

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Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members von DeFeo-Jones, Deborah, Barnett, Stanley F, Fu, Sheng, Hancock, Paula J, Haskell, Kathleen M, Leander, Karen R, McAvoy, Elizabeth, Robinson, Ronald G, Duggan, Mark E, Lindsley, Craig W, Zhao, Zhijian, Huber, Hans E, Jones, Raymond E

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Discovery of 2,3,5-trisubstituted pyridine derivatives as potent Akt1 and Akt2 dual inhibitors von Zhao, Zhijian, Leister, William H., Robinson, Ronald G., Barnett, Stanley F., Defeo-Jones, Deborah, Jones, Raymond E., Hartman, George D., Huff, Joel R., Huber, Hans E., Duggan, Mark E., Lindsley, Craig W.

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Allosteric inhibitors of Akt1 and Akt2: A naphthyridinone with efficacy in an A2780 tumor xenograft model von Bilodeau, Mark T., Balitza, Adrienne E., Hoffman, Jacob M., Manley, Peter J., Barnett, Stanley F., Defeo-Jones, Deborah, Haskell, Kathleen, Jones, Raymond E., Leander, Karen, Robinson, Ronald G., Smith, Anthony M., Huber, Hans E., Hartman, George D.

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Allosteric inhibitors of Akt1 and Akt2: Discovery of [1,2,4]triazolo[3,4-f][1,6]naphthyridines with potent and balanced activity von Li, Yiwei, Liang, Jun, Siu, Tony, Hu, Essa, Rossi, Michael A., Barnett, Stanley F., Defeo-Jones, Deborah, Jones, Raymond E., Robinson, Ronald G., Leander, Karen, Huber, Hans E., Mittal, Sachin, Cosford, Nicholas, Prasit, Peppi

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Development of potent, allosteric dual Akt1 and Akt2 inhibitors with improved physical properties and cell activity von Zhao, Zhijian, Robinson, Ronald G., Barnett, Stanley F., Defeo-Jones, Deborah, Jones, Raymond E., Hartman, George D., Huber, Hans E., Duggan, Mark E., Lindsley, Craig W.

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Rapid assembly of diverse and potent allosteric Akt inhibitors von Wu, Zhicai, Robinson, Ronald G., Fu, Sheng, Barnett, Stanley F., Defeo-Jones, Deborah, Jones, Raymond E., Kral, Astrid M., Huber, Hans E., Kohl, Nancy E., Hartman, George D., Bilodeau, Mark T.

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The design and synthesis of potent and cell-active allosteric dual Akt 1 and 2 inhibitors devoid of hERG activity von Siu, Tony, Li, Yiwei, Nagasawa, Johnny, Liang, Jun, Tehrani, Lida, Chua, Peter, Jones, Raymond E., Defeo-Jones, Deborah, Barnett, Stanley F., Robinson, Ronald G.

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Optimization of 2,3,5-trisubstituted pyridine derivatives as potent allosteric Akt1 and Akt2 inhibitors von Hartnett, John C., Barnett, Stanley F., Bilodeau, Mark T., Defeo-Jones, Deborah, Hartman, George D., Huber, Hans E., Jones, Raymond E., Kral, Astrid M., Robinson, Ronald G., Wu, Zhicai

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Discovery of potent and cell-active allosteric dual Akt 1 and 2 inhibitors von Siu, Tony, Liang, Jun, Arruda, Jeannie, Li, Yiwei, Jones, Raymond E., Defeo-Jones, Deborah, Barnett, Stanley F., Robinson, Ronald G.

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Development of Pyridopyrimidines as Potent Akt1/2 Inhibitors von Wu, Zhicai, Hartnett, John C., Neilson, Lou Anne, Robinson, Ronald G., Fu, Sheng, Barnett, Stanley F., Defeo-Jones, Deborah, Jones, Raymond E., Kral, Astrid M., Huber, Hans E., Hartman, George D., Bilodeau, Mark T.

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Synthesis and biological evaluation of unnatural canthine alkaloids von Lindsley, Craig W., Bogusky, Michael J., Leister, William H., McClain, Ray T., Robinson, Ronald G., Barnett, Stanley F., Defeo-Jones, Deborah, Ross, Charles W., Hartman, George D.

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Interactions of the A1 heterogeneous nuclear ribonucleoprotein and its proteolytic derivative, UP1, with RNA and DNA: Evidence for multiple RNA binding domains and salt-dependent b... von Nadler, Steven G, Merrill, Barbara M, Roberts, William J, Keating, Kathleen M, Lisbin, Michael J, Barnett, Stanley F, Wilson, Samuel H, Williams, Kenneth R

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Interfacial Catalysis by Phosphoinositide 3'-Hydroxykinase von Barnett, Stanley F, Ledder, Lynette M, Stirdivant, Steven M, Ahern, Janet, Conroy, Robert R, Heimbrook, David C

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Primary structure differences between proteins C1 and C2 of HeLa 40S nuclear ribonucleoprotein particles von Merrill, B M, Barnett, S F, LeStourgeon, W M, Williams, K R

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Allosteric inhibitors of Aktl and Akt2 : Discovery of [1,2,4]triazolo[3,4-f][1,6]naphthyridines with potent and balanced activity von YIWEI LI, JUN LIANG, HUBER, Hans E, MITTAL, Sachin, COSFORD, Nicholas, PRASIT, Peppi, SIU, Tony, HU, Essa, ROSSI, Michael A, BARNETT, Stanley F, DEFEO-JONES, Deborah, JONES, Raymond E, ROBINSON, Ronald G, LEANDER, Karen

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Allosteric inhibitors of Aktl and Akt2 : A naphthyridinone with efficacy in an A2780 tumor xenograft model von BILODEAU, Mark T, BALITZA, Adrienne E, SMITH, Anthony M, HUBER, Hans E, HARTMAN, George D, HOFFMAN, Jacob M, MANLEY, Peter J, BARNETT, Stanley F, DEFEO-JONES, Deborah, HASKELL, Kathleen, JONES, Raymond E, LEANDER, Karen, ROBINSON, Ronald G

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