The COMET Handbook: version 1.0 von Williamson, Paula R, Altman, Douglas G, Bagley, Heather, Barnes, Karen L, Blazeby, Jane M, Brookes, Sara T, Clarke, Mike, Gargon, Elizabeth, Gorst, Sarah, Harman, Nicola, Kirkham, Jamie J, McNair, Angus, Prinsen, Cecilia A C, Schmitt, Jochen, Terwee, Caroline B, Young, Bridget

Volltext

Safety, Tolerability, Pharmacokinetics, and Antimalarial Activity of the Novel Plasmodium Phosphatidylinositol 4-Kinase Inhibitor MMV390048 in Healthy Volunteers von Sinxadi, Phumla, Donini, Cristina, Johnstone, Hilary, Langdon, Grant, Wiesner, Lubbe, Allen, Elizabeth, Duparc, Stephan, Chalon, Stephan, McCarthy, James S, Lorch, Ulrike, Chibale, Kelly, Möhrle, Jörg, Barnes, Karen I

Volltext

Spatiotemporal spread of Plasmodium falciparum mutations for resistance to sulfadoxine-pyrimethamine across Africa, 1990–2020 von Flegg, Jennifer A, Humphreys, Georgina S, Montanez, Brenda, Strickland, Taryn, Jacome-Meza, Zaira J, Barnes, Karen I, Raman, Jaishree, Guerin, Philippe J, Hopkins Sibley, Carol, Dahlström Otienoburu, Sabina

Volltext

A legacy of progress in clinical pharmacology and social justice; remembering Peter Ian Folb von Barnes, Karen I, Olliaro, Piero, Gomes, Melba F

Volltext

Severe Acute Malnutrition Results in Lower Lumefantrine Exposure in Children Treated With Artemether‐Lumefantrine for Uncomplicated Malaria von Chotsiri, Palang, Denoeud‐Ndam, Lise, Baudin, Elisabeth, Guindo, Ousmane, Diawara, Halimatou, Attaher, Oumar, Smit, Michiel, Guerin, Philippe J., Doumbo, Ogobara K., Wiesner, Lubbe, Barnes, Karen I., Hoglund, Richard M., Dicko, Alassane, Etard, Jean‐Francois, Tarning, Joel

Volltext

Use of population pharmacokinetic-pharmacodynamic modelling to inform antimalarial dose optimization in infants von Banda, Clifford G, Tarning, Joel, Barnes, Karen I

Volltext

Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use... von Raman, Jaishree, Kagoro, Frank M, Mabuza, Aaron, Malatje, Gillian, Reid, Anthony, Frean, John, Barnes, Karen I

Volltext

Resistant malaria parasites gaining momentum in Africa von Mlugu, Eulambius M, Dondorp, Arjen M, Barnes, Karen I

Volltext

Efficacy of Single-Dose Primaquine With Artemisinin Combination Therapy on Plasmodium falciparum Gametocytes and Transmission: An Individual Patient Meta-Analysis von Stepniewska, Kasia, Humphreys, Georgina S, Gonçalves, Bronner P, Craig, Elaine, Gosling, Roly, Guerin, Philippe J, Price, Ric N, Barnes, Karen I, Raman, Jaishree, Smit, Menno R, D’Alessandro, Umberto, Stone, Will J R, Bjorkman, Anders, Samuels, Aaron M, Arroyo-Arroyo, Maria I, Bastiaens, Guido J H, Brown, Joelle M, Dicko, Alassane, El-Sayed, Badria B, Elzaki, Salah-Eldin G, Eziefula, Alice C, Kariuki, Simon, Kwambai, Titus K, Maestre, Amanda E, Martensson, Andreas, Mosha, Dominic, Mwaiswelo, Richard O, Ngasala, Billy E, Okebe, Joseph, Roh, Michelle E, Sawa, Patrick, Tiono, Alfred B, Chen, Ingrid, Drakeley, Chris J, Bousema, Teun

Volltext

Why is WHO failing women with falciparum malaria in the first trimester of pregnancy? von McGready, Rose, Nosten, François, Barnes, Karen I, Mokuolu, Olugbenga, White, Nicholas J

Volltext

Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis von Hoglund, Richard M, Workman, Lesley, Edstein, Michael D, Thanh, Nguyen Xuan, Quang, Nguyen Ngoc, Zongo, Issaka, Ouedraogo, Jean Bosco, Borrmann, Steffen, Mwai, Leah, Nsanzabana, Christian, Price, Ric N, Dahal, Prabin, Sambol, Nancy C, Parikh, Sunil, Nosten, Francois, Ashley, Elizabeth A, Phyo, Aung Pyae, Lwin, Khin Maung, McGready, Rose, Day, Nicholas P J, Guerin, Philippe J, White, Nicholas J, Barnes, Karen I, Tarning, Joel

Volltext

Hitting a Moving Target: A Model for Malaria Elimination in the Presence of Population Movement von Silal, Sheetal Prakash, Little, Francesca, Barnes, Karen Irma, White, Lisa Jane

Volltext

Impact of the large-scale deployment of artemether/lumefantrine on the malaria disease burden in Africa: case studies of South Africa, Zambia and Ethiopia von Barnes, Karen I, Chanda, Pascalina, Ab Barnabas, Gebre

Volltext

Exploring the seasonality of reported treated malaria cases in Mpumalanga, South Africa von Silal, Sheetal Prakash, Barnes, Karen I, Kok, Gerdalize, Mabuza, Aaron, Little, Francesca

Volltext

Effect of dihydroartemisinin/piperaquine for malaria intermittent preventive treatment on dolutegravir exposure in pregnant women living with HIV von Banda, Clifford G., Nkosi, Dumisile, Allen, Elizabeth, Workman, Lesley, Madanitsa, Mwayiwawo, Chirwa, Marumbo, Kapulula, Mayamiko, Muyaya, Sharon, Munharo, Steven, Wiesner, Lubbe, Phiri, Kamija S., Mwapasa, Victor, Ter Kuile, Feiko O., Maartens, Gary, Barnes, Karen I.

Volltext

Making data map-worthy—enhancing routine malaria data to support surveillance and mapping of Plasmodium falciparum anti-malarial resistance in a pre-elimination sub-Saharan African... von Kagoro, Frank M, Allen, Elizabeth, Mabuza, Aaron, Workman, Lesley, Magagula, Ray, Kok, Gerdalize, Davies, Craig, Malatje, Gillian, Guérin, Philippe J, Dhorda, Mehul, Maude, Richard J, Raman, Jaishree, Barnes, Karen I

Volltext

Safety and tolerability of single low-dose primaquine in a low-intensity transmission area in South Africa: an open-label, randomized controlled trial von Raman, Jaishree, Allen, Elizabeth, Workman, Lesley, Mabuza, Aaron, Swanepoel, Hendrik, Malatje, Gillian, Frean, John, Wiesner, Lubbe, Barnes, Karen I

Volltext

Safety, Tolerability, and Parasite Clearance Kinetics in Controlled Human Malaria Infection after Direct Venous Inoculation of Plasmodium falciparum Sporozoites: A Model for Evalua... von Chughlay, M. Farouk, Chalon, Stephan, El Gaaloul, Myriam, Gobeau, Nathalie, Möhrle, Jörg J., Berghmans, Pieter-Jan, Van Leuven, Katrin, Marx, Michael W., Rosanas-Urgell, Anna, Flynn, Julia, Escoffier, Emilie, Izquierdo-Juncàs, Daniel, Jansen, Bastiaan, Mitov, Venelin, Kümmel, Anne, Van Geertruyden, Jean-Pierre, Barnes, Karen I.

Volltext

Mapping genetic markers of artemisinin resistance in Plasmodium falciparum malaria in Asia: a systematic review and spatiotemporal analysis von Kagoro, Frank M, Barnes, Karen I, Marsh, Kevin, Ekapirat, Nattwut, Mercado, Chris Erwin G, Sinha, Ipsita, Humphreys, Georgina, Dhorda, Mehul, Guerin, Philippe J, Maude, Richard J

Volltext

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Coadministered Ruxolitinib and Artemether-Lumefantrine in Healthy Adults von Chughlay, M Farouk, Barnes, Karen I, El Gaaloul, Myriam, Abla, Nada, Möhrle, Jörg J, Griffin, Paul, van Giersbergen, Paul, Reuter, Stephanie E, Schultz, Hayley B, Kress, Anita, Tapley, Peter, Webster, Rebecca A, Wells, Timothy, McCarthy, James S, Barber, Bridget E, Marquart, Louise, Boyle, Michelle J, Engwerda, Christian R, Chalon, Stephan

Volltext