Pharmacokinetics, mass balance, tissue distribution, metabolism, and excretion of praliciguat, a clinical‐stage soluble guanylate cyclase stimulator in rats von Banijamali, Ali R., Carvalho, Andrew E., Wakefield, James D., Germano, Peter, Barden, Timothy C., Tobin, Jenny V., Zimmer, Daniel P., Masferrer, Jaime L., Profy, Albert T., Currie, Mark G., Todd Milne, G.

Volltext

Discovery of CYR715: A novel carboxylic acid-containing soluble guanylate cyclase stimulator von Rennie, Glen R., Barden, Timothy C., Bernier, Sylvie G., Carvalho, Andrew, Deming, Renee, Germano, Peter, Hudson, Colleen, Im, G-Yoon J., Iyengar, Rajesh R., Jia, Lei, Jung, Joon, Kim, Elise, Lee, Thomas W.-H., Mermerian, Ara, Moore, Joel, Nakai, Takashi, Perl, Nicholas R., Tobin, Jenny, Zimmer, Daniel P., Renhowe, Paul A.

Volltext

Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans von Nakai, Takashi, Perl, Nicholas R, Barden, Timothy C, Carvalho, Andrew, Fretzen, Angelika, Germano, Peter, Im, G-Yoon J, Jin, Hong, Kim, Charles, Lee, Thomas W.-H, Long, Kimberly, Moore, Joel, Rohde, Jason M, Sarno, Renee, Segal, Chrissie, Solberg, Erik O, Tobin, Jenny, Zimmer, Daniel P, Currie, Mark G

Volltext

Nucleophilic addition reactions of 2-nitro-1-(phenylsulfonyl)indole. A new synthesis of 3-substituted-2-nitroindoles von Pelkey, Erin T., Barden, Timothy C., Gribble, Gordon W.

Volltext

Syntheses and Diels-Alder cycloaddition reactions of 4H-furo[3,4-b]indoles. A regiospecific Diels-Alder synthesis of ellipticine von Gribble, Gordon W., Keavy, Daniel J., Davis, Deborah A., Saulnier, Mark G., Pelcman, Benjamin, Barden, Timothy C., Sibi, Mukund P., Olson, Erik R., BelBruno, Joseph J.

Volltext

Discrimination between exo- and endo-3,2-methyl shifts in substituted 2-norbornyl cations on the (+)-camphenilone route to (-)-albene von Baldwin, John E, Barden, Timothy C

Volltext

"Glycylcyclines". 3. 9-Aminodoxycyclinecarboxamides von Barden, Timothy C, Buckwalter, Brian L, Testa, Raymond T, Petersen, Peter J, Lee, Ving J

Volltext

Thermal stereomutations of (2R,3R)-phenylcyclopropane-1,2,3-2H3 and (1R,2S,3R)-phenylcyclopropane-2-13C-1,2,3-2H3: quantification of all four stereochemical modes for interconversi... von Baldwin, John E, Barden, Timothy C

Volltext

Restricted Nitrogen Inversion in 9,10- Diazatetracyclo[6.3.0.0.4,110.5,9]undecanes. Dynamic NMR Studies von Bushweller, C. Hackett, Brown, Jay H, Harpp, Karen S, Hirth, Bradford H, Barden, Timothy C, D'Albi, John N, Gribble, Gordon W

Volltext

Discovery of IWP-051, a Novel Orally Bioavailable Soluble Guanylate Cyclase Stimulator with Sustained and Dose-Dependent Hemodynamic Effects von Nakai, Takashi, Perl, Nicholas R, Iyengar, Rajesh R, Mermerian, Ara, Im, G-Yoon J, Lee, Thomas W-H, Rennie, Glen R, Jia, James, Renhowe, Paul A, Barden, Timothy C, Sheppeck, James E, Iyer, Karthik, Jung, Joon, Milne, G Todd, Segal, Chrissie, Long, Kimberly, Miyashiro, Joy, Bernier, Sylvie, Jacobson, Sarah, Tobin, Jenny, Shea, Courtney, Germano, Peter, Chien, Yueh-tyng, Zimmer, Daniel

Volltext

Stereocontrolled total syntheses of (-)-hobartine and (+)-aristoteline via an intramolecular nitrone-olefin cycloaddition von Gribble, Gordon W., Barden, Timothy C.

Volltext

Partial loss of deuterium label in Wilkinson's catalyst promoted decarbonylations of deuterioaldehydes von Baldwin, John E, Barden, Timothy C, Pugh, Ruth L, Widdison, Wayne C

Volltext

Absolute configurations, maximum rotations, and kinetics of thermal racemization of the 1-phenyl-2-deuteriocyclopropanes von Baldwin, John E, Barden, Timothy C

Volltext

A directed metalation route to the zwitterionic indole alkaloids von Gribble, Gordon W., Barden, Timothy C., Johnson, David A.

Volltext

ChemInform Abstract: Indoles: Industrial, Agricultural and Over-the-counter Uses von Barden, Timothy C.

Volltext

Stereochemical kinetics of the thermal stereomutations interconverting achiral isomers of 1-phenyl-1,2,3-trideuteriocyclopropane von Baldwin, John E, Patapoff, Thomas W, Barden, Timothy C

Volltext

Reinterpretation of two degradations of (-)-albene von Baldwin, John E, Barden, Timothy C, Cianciosi, Steven J

Volltext

Absolute stereochemistry of (-)-albene von Baldwin, John E, Barden, Timothy C

Volltext

Total synthesis of (.+-.)-albene von Baldwin, John E, Barden, Timothy C

Volltext

FAAH INHIBITORS von SPROTT, KEVIN, HUDSON, COLLEEN, JIA, JAMES, MERMERIAN, ARA, PENG, BO, BARDEN, TIMOTHY C, FRETZEN, ANGELIKA, YANG, JANE, YU, XIANG

Volltext bestellen