Oxidative stress in ALS: Key role in motor neuron injury and therapeutic target von Barber, Siân C., Shaw, Pamela J.

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Oxidative stress in ALS: A mechanism of neurodegeneration and a therapeutic target von Barber, Siân C., Mead, Richard J., Shaw, Pamela J.

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An in vitro screening cascade to identify neuroprotective antioxidants in ALS von Barber, Siân C., Higginbottom, Adrian, Mead, Richard J., Barber, Stuart, Shaw, Pamela J.

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S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis von Mead, Richard J., Higginbottom, Adrian, Allen, Scott P., Kirby, Janine, Bennett, Ellen, Barber, Siân C., Heath, Paul R., Coluccia, Antonio, Patel, Neelam, Gardner, Iain, Brancale, Andrea, Grierson, Andrew J., Shaw, Pamela J.

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Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS von Kirby, Janine, Halligan, Eugene, Baptista, Melisa J., Allen, Simon, Heath, Paul R., Holden, Hazel, Barber, Sian C., Loynes, Catherine A., Wood-Allum, Clare A., Lunec, Joseph, Shaw, Pamela J.

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Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen von Wood-Allum, Clare A., Barber, Siân C., Kirby, Janine, Heath, Paul, Holden, Hazel, Mead, Richard, Higginbottom, Adrian, Allen, Simon, Beaujeux, Tim, Alexson, Stefan E., Ince, Paul G., Shaw, Pamela J.

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A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function von Sargsyan, Siranush A, Blackburn, Daniel J, Barber, Siân C, Grosskreutz, Julian, De Vos, Kurt J, Monk, Peter N, Shaw, Pamela J

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Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1 von Sargsyan, Siranush A, Blackburn, Daniel J, Barber, Siân C, Monk, Peter N, Shaw, Pamela J

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S1P and LPA trigger Schwann cell actin changes and migration von Barber, Siân C., Mellor, Harry, Gampel, Alex, Scolding, Neil J.

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Impairment of mitochondrial anti-oxidant defence in SOD I-related motor neuron injury and amelioration by ebselen von WOOD-ALLUM, Clare A, BARBER, Sian C, INCE, Paul G, SHAW, Pamela J, KIRBY, Janine, HEATH, Paul, HOLDEN, Hazel, MEAD, Richard, HIGGINBOTTOM, Adrian, ALLEN, Simon, BEAUJEUX, Tim, ALEXSON, Stefan E

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Mutant SOD I alters the motor neuronal transcriptome : implications for familial ALS von KIRBY, Janine, HALLIGAN, Eugene, SHAW, Pamela J, BAPTISTA, Melisa J, ALLEN, Simon, HEATH, Paul R, HOLDEN, Hazel, BARBER, Sian C, LOYNES, Catherine A, WOOD-ALLUM, Clare A, LUNEC, Joseph

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GSK137, a potent small-molecule BCL6 inhibitor with in vivo activity, suppresses antibody responses in mice von Pearce, Andrew C., Bamford, Mark J., Barber, Ruth, Bridges, Angela, Convery, Maire A., Demetriou, Constantinos, Evans, Sian, Gobbetti, Thomas, Hirst, David J., Holmes, Duncan S., Hutchinson, Jonathan P., Jayne, Sandrine, Lezina, Larissa, McCabe, Michael T., Messenger, Cassie, Morley, Joanne, Musso, Melissa C., Scott-Stevens, Paul, Manso, Ana Sousa, Schofield, Jennifer, Slocombe, Tom, Somers, Don, Walker, Ann L., Wyce, Anastasia, Zhang, Xi-Ping, Wagner, Simon D.

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Synthetic Lethal Screen Demonstrates That a JAK2 Inhibitor Suppresses a BCL6-dependent IL10RA/JAK2/STAT3 Pathway in High Grade B-cell Lymphoma von Beck, Daniel, Zobel, Jenny, Barber, Ruth, Evans, Sian, Lezina, Larissa, Allchin, Rebecca L., Blades, Matthew, Elliott, Richard, Lord, Christopher J., Ashworth, Alan, Porter, Andrew C.G., Wagner, Simon D.

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