E-Cadherin-Mediated Cell Coupling Is Required for Apoptotic Cell Extrusion von Lubkov, Veronica, Bar-Sagi, Dafna

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Regulating the regulator: post-translational modification of RAS von Ahearn, Ian M., Haigis, Kevin, Bar-Sagi, Dafna, Philips, Mark R.

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Determining the macropinocytic index of cells through a quantitative image-based assay von Commisso, Cosimo, Flinn, Rory J, Bar-Sagi, Dafna

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Crosstalk between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer von Jang, Jung-Eun, Hajdu, Cristina H., Liot, Caroline, Miller, George, Dustin, Michael L., Bar-Sagi, Dafna

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Oncogenic Kras-Induced GM-CSF Production Promotes the Development of Pancreatic Neoplasia von Pylayeva-Gupta, Yuliya, Lee, Kyoung Eun, Hajdu, Cristina H., Miller, George, Bar-Sagi, Dafna

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A Mouse Model of Hereditary Pancreatitis Generated by Transgenic Expression of R122H Trypsinogen von Archer, Herbert, Jura, Natalia, Keller, James, Jacobson, Matthew, Bar–Sagi, Dafna

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Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis von Sparmann, Anke, Bar-Sagi, Dafna

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Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein von Kamphorst, Jurre J, Nofal, Michel, Commisso, Cosimo, Hackett, Sean R, Lu, Wenyun, Grabocka, Elda, Vander Heiden, Matthew G, Miller, George, Drebin, Jeffrey A, Bar-Sagi, Dafna, Thompson, Craig B, Rabinowitz, Joshua D

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Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor von Connolly, Michael K, Mallen-St Clair, Jon, Bedrosian, Andrea S, Malhotra, Ashim, Vera, Valery, Ibrahim, Junaid, Henning, Justin, Pachter, H Leon, Bar-Sagi, Dafna, Frey, Alan B, Miller, George

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An orthosteric inhibitor of the Ras-Sos interaction von Patgiri, Anupam, Yadav, Kamlesh K, Arora, Paramjit S, Bar-Sagi, Dafna

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Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells von Commisso, Cosimo, Davidson, Shawn M., Soydaner-Azeloglu, Rengin G., Parker, Seth J., Kamphorst, Jurre J., Hackett, Sean, Grabocka, Elda, Nofal, Michel, Drebin, Jeffrey A., Thompson, Craig B., Rabinowitz, Joshua D., Metallo, Christian M., Vander Heiden, Matthew G., Bar-Sagi, Dafna

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BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis von Das, Shipra, Bar-Sagi, Dafna

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IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia von Pylayeva-Gupta, Yuliya, Das, Shipra, Handler, Jesse S, Hajdu, Cristina H, Coffre, Maryaline, Koralov, Sergei B, Bar-Sagi, Dafna

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The F-Box Domain-Dependent Activity of EMI1 Regulates PARPi Sensitivity in Triple-Negative Breast Cancers von Marzio, Antonio, Puccini, Joseph, Kwon, Youngho, Maverakis, Natalia K., Arbini, Arnaldo, Sung, Patrick, Bar-Sagi, Dafna, Pagano, Michele

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Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors von Davidson, Shawn M, Jonas, Oliver, Keibler, Mark A, Hou, Han Wei, Luengo, Alba, Mayers, Jared R, Wyckoff, Jeffrey, Del Rosario, Amanda M, Whitman, Matthew, Chin, Christopher R, Condon, Kendall J, Lammers, Alex, Kellersberger, Katherine A, Stall, Brian K, Stephanopoulos, Gregory, Bar-Sagi, Dafna, Han, Jongyoon, Rabinowitz, Joshua D, Cima, Michael J, Langer, Robert, Vander Heiden, Matthew G

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EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion von Marzio, Antonio, Kurz, Emma, Sahni, Jennifer M., Di Feo, Giuseppe, Puccini, Joseph, Jiang, Shaowen, Hirsch, Carolina Alcantara, Arbini, Arnaldo A., Wu, Warren L., Pass, Harvey I., Bar-Sagi, Dafna, Papagiannakopoulos, Thales, Pagano, Michele

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Molecular pathways: targeting the dependence of mutant RAS cancers on the DNA damage response von Grabocka, Elda, Commisso, Cosimo, Bar-Sagi, Dafna

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Sos-mediated cross-activation of wild-type Ras by oncogenic Ras is essential for tumorigenesis von Jeng, Hao-Hsuan, Taylor, Laura J, Bar-Sagi, Dafna

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Selective Alanine Transporter Utilization Creates a Targetable Metabolic niche in Pancreatic Cancer von Parker, Seth J., Amendola, Caroline R., Hollinshead, Kate E. R., Yu, Qijia, Yamamoto, Keisuke, Encarnacion-Rosado, Joel, Rose, Rebecca E., LaRue, Madeleine M., Sohn, Albert S. W., Biancur, Doug E., Paulo, Joao A., Gygi, Steven P., Jones, Drew R., Wang, Huamin, Philips, Mark R., Bar-Sagi, Dafna, Mancias, Joseph D., Kimmelman, Alec C.

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MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells von Ochi, Atsuo, Nguyen, Andrew H, Bedrosian, Andrea S, Mushlin, Harry M, Zarbakhsh, Saman, Barilla, Rocky, Zambirinis, Constantinos P, Fallon, Nina C, Rehman, Adeel, Pylayeva-Gupta, Yuliya, Badar, Sana, Hajdu, Cristina H, Frey, Alan B, Bar-Sagi, Dafna, Miller, George

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