Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer von Siravegna, Giulia, Lazzari, Luca, Crisafulli, Giovanni, Sartore-Bianchi, Andrea, Mussolin, Benedetta, Cassingena, Andrea, Martino, Cosimo, Lanman, Richard B., Nagy, Rebecca J., Fairclough, Stephen, Rospo, Giuseppe, Corti, Giorgio, Bartolini, Alice, Arcella, Pamela, Montone, Monica, Lodi, Francesca, Lorenzato, Annalisa, Vanzati, Alice, Valtorta, Emanuele, Cappello, Giovanni, Bertotti, Andrea, Lonardi, Sara, Zagonel, Vittorina, Leone, Francesco, Russo, Mariangela, Balsamo, Antonella, Truini, Mauro, Di Nicolantonio, Federica, Amatu, Alessio, Bonazzina, Erica, Ghezzi, Silvia, Regge, Daniele, Vanzulli, Angelo, Trusolino, Livio, Siena, Salvatore, Marsoni, Silvia, Bardelli, Alberto

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Mitochondrial variants in MT-CO2 and D-loop instability are involved in MUTYH-associated polyposis von Errichiello, Edoardo, Balsamo, Antonella, Cerni, Marianna, Venesio, Tiziana

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A Comprehensive PDX Gastric Cancer Collection Captures Cancer Cell-Intrinsic Transcriptional MSI Traits von Corso, Simona, Isella, Claudio, Bellomo, Sara E, Apicella, Maria, Durando, Stefania, Migliore, Cristina, Ughetto, Stefano, D'Errico, Laura, Menegon, Silvia, Moya-Rull, Daniel, Cargnelutti, Marilisa, Capelôa, Tânia, Conticelli, Daniela, Giordano, Jessica, Venesio, Tiziana, Balsamo, Antonella, Marchiò, Caterina, Degiuli, Maurizio, Reddavid, Rossella, Fumagalli, Uberto, De Pascale, Stefano, Sgroi, Giovanni, Rausa, Emanuele, Baiocchi, Gian Luca, Molfino, Sarah, Pietrantonio, Filippo, Morano, Federica, Siena, Salvatore, Sartore-Bianchi, Andrea, Bencivenga, Maria, Mengardo, Valentina, Rosati, Riccardo, Marrelli, Daniele, Morgagni, Paolo, Rausei, Stefano, Pallabazzer, Giovanni, De Simone, Michele, Ribero, Dario, Marsoni, Silvia, Sottile, Antonino, Medico, Enzo, Cassoni, Paola, Sapino, Anna, Pectasides, Eirini, Thorner, Aaron R, Nag, Anwesha, Drinan, Samantha D, Wollison, Bruce M, Bass, Adam J, Giordano, Silvia

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Effective Activity of Cytokine-Induced Killer Cells against Autologous Metastatic Melanoma Including Cells with Stemness Features von GAMMAITONI, Loretta, GIRAUDO, Lidia, CARAVELLI, Daniela, GIACONE, Elena, VENESIO, Tiziana, BALSAMO, Antonella, PIGNOCHINO, Ymera, GRIGNANI, Giovanni, CARNEVALE-SCHIANCA, Fabrizio, AGLIETTA, Massimo, SANGIOLO, Dario, LEUCI, Valeria, TODOROVIC, Maja, MESIANO, Giulia, PICCIOTTO, Franco, PISACANE, Alberto, ZACCAGNA, Alessandro, VOLPE, Maria Giuseppa, GALLO, Susanna

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Altered molecular pathways in melanocytic lesions von Scatolini, Maria, Grand, Maurizia Mello, Grosso, Enrico, Venesio, Tiziana, Pisacane, Alberto, Balsamo, Antonella, Sirovich, Roberta, Risio, Mauro, Chiorino, Giovanna

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Screening for the FIG-ROS1 fusion in biliary tract carcinomas by nested PCR von Peraldo Neia, Caterina, Cavalloni, Giuliana, Balsamo, Antonella, Venesio, Tiziana, Napoli, Francesca, Sassi, Francesco, Martin, Vittoria, Frattini, Milo, Aglietta, Massimo, Leone, Francesco

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Metabolomic Investigation of β-Thalassemia in Chorionic Villi Samples von Monni, Giovanni, Murgia, Federica, Corda, Valentina, Peddes, Cristina, Iuculano, Ambra, Tronci, Laura, Balsamo, Antonella, Atzori, Luigi

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Oxidative DNA damage drives carcinogenesis in MUTYH-associated-polyposis by specific mutations of mitochondrial and MAPK genes von Venesio, Tiziana, Balsamo, Antonella, Errichiello, Edoardo, Ranzani, Guglielmina N, Risio, Mauro

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Abstract A087: Empowering precision medicine in metastatic colorectal cancer: preliminary results from the FUNNEL platform von Martino, Cosimo, Berrino, Enrico, Dell'Aglio, Carmine, Casorzo, Laura, Panero, Mara, Siena, Salvatore, Sartore-Bianchi, Andrea, Cassingena, Andrea, Zagonel, Vittorina, Lonardi, Sara, Loupakis, Fotios, Tonini, Giuseppe, Racca, Patrizia, Trusolino, Livio, Bertotti, Andrea, Depetris, Ilaria, Balsamo, Antonella, Sapino, Anna, Marsoni, Silvia

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Abstract 2848: Radiographic and genomic evolution of individual metastases during HER2 blockade in colorectal cancer von Siravegna, Giulia, Lazzari, Luca, Sartore-Bianchi, Andrea, Crisafulli, Giovanni, Mussolin, Benedetta, Cassingena, Andrea, Martino, Cosimo, Lanman, Richard, Nagy, Rebecca, Corti, Giorgio, Bartolini, Alice, Arcella, Pamela, Montone, Monica, Lodi, Francesca, Vanzati, Alice, Valtorta, Emanuele, Cappello, Giovanni, Bertotti, Andrea, Lonardi, Sara, Zagonel, Vittorina, Leone, Francesco, Russo, Mariangela, Balsamo, Antonella, Truini, Mauro, Nicolantonio, Federica Di, Amatu, Alessio, Bonazzina, Erica, Ghezzi, Silvia, Regge, Daniele, Vanzulli, Angelo, Trusolino, Livio, Siena, Salvatore, Marsoni, Silvia, Bardelli, Alberto

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Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer von Siravegna, Giulia, Lazzari, Luca, Crisafulli, Giovanni, Sartore-Bianchi, Andrea, Mussolin, Benedetta, Cassingena, Andrea, Martino, Cosimo, Lanman, Richard B, Nagy, Rebecca J, Fairclough, Stephen, Rospo, Giuseppe, Corti, Giorgio, Bartolini, Alice, Arcella, Pamela, Montone, Monica, Lodi, Francesca, Lorenzato, Annalisa, Vanzati, Alice, Valtorta, Emanuele, Cappello, Giovanni, Bertotti, Andrea, Lonardi, Sara, Zagonel, Vittorina, Leone, Francesco, Russo, Mariangela, Balsamo, Antonella, Truini, Mauro, Di Nicolantonio, Federica, Amatu, Alessio, Bonazzina, Erica, Ghezzi, Silvia, Regge, Daniele, Vanzulli, Angelo, Trusolino, Livio, Siena, Salvatore, Marsoni, Silvia, Bardelli, Alberto

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Colorectal Adenomatous Polyposis: Heterogeneity of Susceptibility Gene Mutations and Phenotypes in a Cohort of Italian Patients von Marabelli, Monica, Molinaro, Valeria, Abou Khouzam, Raefa, Berrino, Enrico, Panero, Mara, Balsamo, Antonella, Venesio, Tiziana, Ranzani, Guglielmina Nadia

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MUTYH-associated polyposis (MAP), the syndrome implicating base excision repair in inherited predisposition to colorectal tumors von Venesio, Tiziana, Balsamo, Antonella, D'Agostino, Vito G, Ranzani, Guglielmina N

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Genetic polymorphisms of CYP17A1, vitamin D receptor and androgen receptor in Italian heredo-familial and sporadic prostate cancers von Risio, Mauro, Venesio, Tiziana, Kolomoets, Elena, Armaroli, Paola, Gallo, Federica, Balsamo, Antonella, Muto, Giovanni, D’Urso, Leonardo, Puppo, Paolo, Naselli, Angelo, Segnan, Nereo

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Constitutional high expression of an APC mRNA isoform in a subset of attenuated familial adenomatous polyposis patients von VENESIO, Tiziana, BALSAMO, Antonella, SFILIGOI, Christian, FUSO, Luca, MOLATORE, Sara, RANZANI, Guglielmina Nadia, RISIO, Mauro

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In melanocytic lesions the fraction of BRAFV600E alleles is associated with sun exposure but unrelated to ERK phosphorylation von Venesio, Tiziana, Chiorino, Giovanna, Balsamo, Antonella, Zaccagna, Alessandro, Petti, Consalvo, Scatolini, Maria, Pisacane, Alberto, Sarotto, Ivana, Picciotto, Franco, Risio, Mauro

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In melanocytic lesions the fraction of BRAF V600E alleles is associated with sun exposure but unrelated to ERK phosphorylation von Venesio, Tiziana, Chiorino, Giovanna, Balsamo, Antonella, Zaccagna, Alessandro, Petti, Consalvo, Scatolini, Maria, Pisacane, Alberto, Sarotto, Ivana, Picciotto, Franco, Risio, Mauro

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APC Haploinsufficiency, but Not CTNNB1 or CDH1 Gene Mutations, Accounts for a Fraction of Familial Adenomatous Polyposis Patients Without APC Truncating Mutations von Venesio, Tiziana, Balsamo, Antonella, Rondo-Spaudo, Marco, Varesco, Liliana, Risio, Mauro, Ranzani, Guglielmina Nadia

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Germline APC Mutation on the β-Catenin Binding Site Is Associated with a Decreased Apoptotic Level in Colorectal Adenomas von Venesio, Tiziana, Balsamo, Antonella, Scordamaglia, Antonella, Bertolaso, Marta, Arrigoni, Arrigo, Sprujevnik, Tatiana, Rossini, Francesco P, Risio, Mauro

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Germline APC Mutation on the -Catenin Binding Site Is Associated with a Decreased Apoptotic Level in Colorectal Adenomas von Venesio, Tiziana, Balsamo, Antonella, Scordamaglia, Antonella, Bertolaso, Marta, Arrigoni, Arrigo, Sprujevnik, Tatiana, Rossini, Francesco P, Risio, Mauro

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