Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth von Abu Aboud, Omran, Chen, Ching-Hsien, Senapedis, William, Baloglu, Erkan, Argueta, Christian, Weiss, Robert H

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Nucleo-cytoplasmic transport as a therapeutic target of cancer von Gravina, Giovanni Luca, Senapedis, William, McCauley, Dilara, Baloglu, Erkan, Shacham, Sharon, Festuccia, Claudio

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The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic Leukemia von Vercruysse, Thomas, De Bie, Jolien, Neggers, Jasper E, Jacquemyn, Maarten, Vanstreels, Els, Schmid-Burgk, Jonathan L, Hornung, Veit, Baloglu, Erkan, Landesman, Yosef, Senapedis, William, Shacham, Sharon, Dagklis, Antonis, Cools, Jan, Daelemans, Dirk

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Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes von Neggers, Jasper Edgar, Kwanten, Bert, Dierckx, Tim, Noguchi, Hiroki, Voet, Arnout, Bral, Lotte, Minner, Kristien, Massant, Bob, Kint, Nicolas, Delforge, Michel, Vercruysse, Thomas, Baloglu, Erkan, Senapedis, William, Jacquemyn, Maarten, Daelemans, Dirk

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A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action von Campaner, Elena, Rustighi, Alessandra, Zannini, Alessandro, Cristiani, Alberto, Piazza, Silvano, Ciani, Yari, Kalid, Ori, Golan, Gali, Baloglu, Erkan, Shacham, Sharon, Valsasina, Barbara, Cucchi, Ulisse, Pippione, Agnese Chiara, Lolli, Marco Lucio, Giabbai, Barbara, Storici, Paola, Carloni, Paolo, Rossetti, Giulia, Benvenuti, Federica, Bello, Ezia, D’Incalci, Maurizio, Cappuzzello, Elisa, Rosato, Antonio, Del Sal, Giannino

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Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma von Aboukameel, Amro, Muqbil, Irfana, Senapedis, William, Baloglu, Erkan, Landesman, Yosef, Shacham, Sharon, Kauffman, Michael, Philip, Philip A, Mohammad, Ramzi M, Azmi, Asfar S

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Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor von Subhash, Vinod Vijay, Yeo, Mei Shi, Wang, Lingzhi, Tan, Shi Hui, Wong, Foong Ying, Thuya, Win Lwin, Tan, Woei Loon, Peethala, Praveen C., Soe, Mu Yar, Tan, David S. P., Padmanabhan, Nisha, Baloglu, Erkan, Shacham, Sharon, Tan, Patrick, Koeffler, H. Phillip, Yong, Wei Peng

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Clinical Implications of Targeting XPO1-mediated Nuclear Export in Multiple Myeloma von Gandhi, Ujjawal H., Senapedis, William, Baloglu, Erkan, Unger, Thaddeus J., Chari, Ajai, Vogl, Dan, Cornell, Robert F.

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Targeting XPO1 and PAK4 in 8505C Anaplastic Thyroid Cancer Cells: Putative Implications for Overcoming Lenvatinib Therapy Resistance von Khan, Husain Yar, Ge, James, Nagasaka, Misako, Aboukameel, Amro, Mpilla, Gabriel, Muqbil, Irfana, Szlaczky, Mark, Chaker, Mahmoud, Baloglu, Erkan, Landesman, Yosef, Mohammad, Ramzi M, Azmi, Asfar S, Sukari, Ammar

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Targeting Nuclear Exporter Protein XPO1/CRM1 in Gastric Cancer von Sexton, Rachel, Mahdi, Zaid, Chaudhury, Rahman, Beydoun, Rafic, Aboukameel, Amro, Khan, Husain Y, Baloglu, Erkan, Senapedis, William, Landesman, Yosef, Tesfaye, Anteneh, Kim, Steve, Philip, Philip A, Azmi, Asfar S

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Oral eltanexor treatment of patients with higher-risk myelodysplastic syndrome refractory to hypomethylating agents von Lee, Sangmin, Mohan, Sanjay, Knupp, Jessica, Chamoun, Kamal, de Jonge, Adrienne, Yang, Fan, Baloglu, Erkan, Shah, Jatin, Kauffman, Michael G, Shacham, Sharon, Bhatnagar, Bhavana

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Heterozygous mutation of cysteine528 in XPO1 is sufficient for resistance to selective inhibitors of nuclear export von Neggers, Jasper Edgar, Vanstreels, Els, Baloglu, Erkan, Shacham, Sharon, Landesman, Yosef, Daelemans, Dirk

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Molecular mechanism and therapeutic implications of selinexor (KPT-330) in liposarcoma von Garg, Manoj, Kanojia, Deepika, Mayakonda, Anand, Said, Jonathan W, Doan, Ngan B, Chien, Wenwen, Ganesan, Trivadi S, Chuang, Linda Shyue Huey, Venkatachalam, Nachiyappan, Baloglu, Erkan, Shacham, Sharon, Kauffman, Michael, Koeffler, H Phillip

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Functional Genome-wide Screening Identifies Targets and Pathways Sensitizing Pancreatic Cancer Cells to Dasatinib von Chien, Wenwen, Sudo, Makoto, Ding, Ling-Wen, Sun, Qiao-Yang, Wuensche, Peer, Lee, Kian Leong, Hattori, Norimichi, Garg, Manoj, Xu, Liang, Zheng, Yun, Gery, Sigal, Wongphayak, Sarawut, Yang, Henry, Baloglu, Erkan, Shacham, Sharon, Kauffman, Michael, Mori, Seiichi, Koeffler, H Phillip

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Clinical translation of nuclear export inhibitors in cancer von Senapedis, William T, Baloglu, Erkan, Landesman, Yosef

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Novel phenanthridinone inhibitors of poly(adenosine 5′-diphosphate-ribose) synthetase: Potent cytoprotective and antishock agents von Jagtap, Prakash, Soriano, Francisco Garcia, Virág, László, Liaudet, Lucas, Mabley, Jon, Szabó, Éva, Haskó, György, Marton, Anita, Lorigados, Clara Batista, Gallyas, Ferenc, Sümegi, Balázs, Hoyt, Dale G, Baloglu, Erkan, VanDuzer, John, Salzman, Andrew L, Southan, Garry J, Szabó, Csaba

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Discovery of Potent Poly(ADP-ribose) Polymerase-1 Inhibitors from the Modification of Indeno[1,2-c]isoquinolinone von Jagtap, Prakash G, Baloglu, Erkan, Southan, Garry J, Mabley, Jon G, Li, Hongshan, Zhou, Jing, van Duzer, John, Salzman, Andrew L, Szabó, Csaba

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A novel orally bioavailable compound KPT-9274 inhibits PAK4, and blocks triple negative breast cancer tumor growth von Rane, Chetan, Senapedis, William, Baloglu, Erkan, Landesman, Yosef, Crochiere, Marsha, Das-Gupta, Soumyasri, Minden, Audrey

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The discovery and synthesis of novel adenosine substituted 2,3-dihydro-1H-isoindol-1-ones: potent inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1) von JAGTAP, Prakash G, SOUTHAN, Garry J, BALOGLU, Erkan, RAM, Siya, MABLEY, Jon G, MARTON, Anita, SALZMAN, Andrew, SZABO, Csaba

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Stratonikeia Tiyatrosu’na Ait Antik Dönem Harçlarının Yapılan Analizler Işığında Değerlendirilmesi von BALOĞLU, Erkan, SEZGİN, Tunç, ÖZDEMİR, Mustafa Tuncay

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