Phase I, Open-Label, Dose-Escalation Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of GSK2879552 in Relapsed/Refractory SCLC von Bauer, Todd M., Besse, Benjamin, Martinez-Marti, Alex, Trigo, Jose Manuel, Moreno, Victor, Garrido, Pilar, Ferron-Brady, Geraldine, Wu, Yuehui, Park, Jennifer, Collingwood, Therese, Kruger, Ryan G., Mohammad, Helai P., Ballas, Marc S., Dhar, Arindam, Govindan, Ramaswamy

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A Pilot Study of Sirolimus in Subjects with Cowden Syndrome or Other Syndromes Characterized by Germline Mutations in PTEN von Komiya, Takefumi, Blumenthal, Gideon M., DeChowdhury, Roopa, Fioravanti, Susan, Ballas, Marc S., Morris, John, Hornyak, Thomas J., Wank, Stephen, Hewitt, Stephen M., Morrow, Betsy, Memmott, Regan M., Rajan, Arun, Dennis, Phillip A.

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Phase II trial of lapatinib in adult and pediatric patients with neurofibromatosis type 2 and progressive vestibular schwannomas von Karajannis, Matthias A, Legault, Geneviève, Hagiwara, Mari, Ballas, Marc S, Brown, Krysten, Nusbaum, Annette O, Hochman, Tsivia, Goldberg, Judith D, Koch, Kevin M, Golfinos, John G, Roland, J Thomas, Allen, Jeffrey C

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A Phase II, Open-Label Study of Ramucirumab in Combination with Paclitaxel and Carboplatin as First-Line Therapy in Patients with Stage IIIB/IV Non–Small-Cell Lung Cancer von Camidge, D. Ross, Berge, Eamon M., Doebele, Robert C., Ballas, Marc S., Jahan, Thierry, Haigentz, Missak, Hoffman, David, Spicer, James, West, Howard, Lee, Pablo, Yang, Ling, Joshi, Adarsh, Gao, Ling, Yurasov, Sergey, Mita, Alain

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Rationale for targeting VEGF, FGF, and PDGF for the treatment of NSCLC von Ballas, Marc S, Chachoua, Abraham

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Model‐based meta‐analysis of non‐small cell lung cancer with standard of care PD‐1 inhibitors and chemotherapy for early development decision making von Turner, David C., Wada, Russ, Zhou, Helen, Wang, Xiaowei, Greef, Rik, Valiathan, Chandni, Zhang, Lindsey, Zhang, Nancy, Kuchimanchi, Mita, Chen, Tai‐Tsang, Ballas, Marc, Visser, Sandra A. G.

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Immunodynamics of explanted human tumors for immuno‐oncology von Dubuisson, Agathe, Fahrner, Jean‐Eudes, Goubet, Anne‐Gaëlle, Terrisse, Safae, Voisin, Nicolas, Bayard, Charles, Lofek, Sebastien, Drubay, Damien, Bredel, Delphine, Mouraud, Séverine, Susini, Sandrine, Cogdill, Alexandria, Rebuffet, Lucas, Ballot, Elise, Jacquelot, Nicolas, Thomas de Montpreville, Vincent, Casiraghi, Odile, Radulescu, Camélia, Ferlicot, Sophie, Figueroa, David J, Yadavilli, Sapna, Waight, Jeremy D, Ballas, Marc, Hoos, Axel, Condamine, Thomas, Parier, Bastien, Gaudillat, Christophe, Routy, Bertrand, Ghiringhelli, François, Derosa, Lisa, Breuskin, Ingrid, Rouanne, Mathieu, André, Fabrice, Lebacle, Cédric, Baumert, Hervé, Wislez, Marie, Fadel, Elie, Cremer, Isabelle, Albiges, Laurence, Geoerger, Birgit, Scoazec, Jean‐Yves, Loriot, Yohann, Kroemer, Guido, Marabelle, Aurélien, Bonvalet, Mélodie, Zitvogel, Laurence

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A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors von Blumenthal, Gideon M, Gills, Joell J, Ballas, Marc S, Bernstein, Wendy B, Komiya, Takefumi, Dechowdhury, Roopa, Morrow, Betsy, Root, Hyejeong, Chun, Guinevere, Helsabeck, Cynthia, Steinberg, Seth M, LoPiccolo, Jaclyn, Kawabata, Shigeru, Gardner, Erin R, Figg, William D, Dennis, Phillip A

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A phase I/II study of pemetrexed with sirolimus in advanced, previously treated non-small cell lung cancer von Komiya, Takefumi, Memmott, Regan M., Blumenthal, Gideon M., Bernstein, Wendy, Ballas, Marc S., De Chowdhury, Roopa, Chun, Guinevere, Peer, Cody J., Figg, William D., Liewehr, David J., Steinberg, Seth M., Giaccone, Giuseppe, Szabo, Eva, Kawabata, Shigeru, Tsurutani, Junji, Rajan, Arun, Dennis, Phillip A.

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A Phase II Study of Halichondrin B Analog Eribulin Mesylate (E7389) in Patients with Advanced Non-small Cell Lung Cancer Previously Treated with a Taxane: A California Cancer Conso... von Gitlitz, Barbara J., Tsao-Wei, Denice D., Groshen, Susan, Davies, Angela, Koczywas, Marianna, Belani, Chandra P., Argiris, Athanassios, Ramalingam, Suresh, Vokes, Everett E., Edelman, Martin, Hoffman, Philip, Ballas, Marc S., Liu, Stephen V., Gandara, David R.

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PD-L1 expression in advanced NSCLC: Insights into risk stratification and treatment selection from a systematic literature review von Brody, Robert, Zhang, Yiduo, Ballas, Marc, Siddiqui, Mohd Kashif, Gupta, Palvi, Barker, Craig, Midha, Anita, Walker, Jill

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PTEN hamartomatous tumor syndromes (PHTS): Rare syndromes with great relevance to common cancers and targeted drug development von LoPiccolo, Jaclyn, Ballas, Marc S, Dennis, Phillip A

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Abstract 1849: ICOS co-stimulation in combination immune checkpoint blockade and/or dose-optimized focal irradiation results in enhanced tumor control von Waight, Jeremy D., Bi, Meixia, Hopson, Chris, Yadavilli, Sapna, Hance, Kenneth W., Ballas, Marc, Hoos, Axel

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A Phase III Study of Durvalumab (MEDI4736) With or Without Tremelimumab for Previously Treated Patients With Advanced NSCLC: Rationale and Protocol Design of the ARCTIC Study von Planchard, David, Yokoi, Takashi, McCleod, Michael J, Fischer, Jürgen R, Kim, Young-Chul, Ballas, Marc, Shi, Kelvin, Soria, Jean-Charles

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Real-world immuno-oncology treatment patterns and outcomes in US patients with metastatic non-small-cell lung cancer von Bruno, Amanda, Bell, Kelly, Stafkey-Mailey, Dana, Murty, Sharanya, Ballas, Marc S.

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Evolution of standard of care therapies used for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC): A real-world analysis of patient health records from 201... von Saba, Nabil F., Shukla, Soham, Aguilar, Kathleen M., Ballas, Marc S., Bell, Kelly, Boyd, Marley, Chao, Jessica, Ellis, Catherine Elizabeth, Phiri, Kelesitse, Tseng, Wan-Yu, Nadler, Eric S.

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Abstract 2268: Agonistic T cell non depleting ICOS antibody strongly enhances anti-tumor activity with CTLA4 blocking monoclonal antibody without exacerbating colitis von Coutzac, Clélia, Jouniaux, Jean, Vozy, Aurore, Ballas, Marc, Brett, Sara, Yadavilli, Sapna, Angevin, Eric, Hoos, Axel, Chaput, Nathalie

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Overestimating the influence of the 1999 WHO classification of lung tumors on survival in bronchioloalveloar carcinoma von Tsurutani, Junji, Ballas, Marc S, Dennis, Phillip A

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A slow disengagement from platinum-based chemotherapy for patients with advanced non-small cell lung cancer von Ballas, Marc S., Dennis, Phillip A.

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Abstract 2220: Non-clinical tumor models reveal broad combination potential of ICOS agonist antibodies von Waight, Jeremy D., Bi, Meixia, Kilian, David, Hopson, Christopher, Zhang, Shu-Yun, Brett, Sara, Yadavilli, Sapna, Zhang, Tianqian, Shi, Hong, Hance, Kenneth W., Ballas, Marc, Hoos, Axel

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