Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model von Weinberg, Robert A, Ma, Li, Reinhardt, Ferenc, Pan, Elizabeth, Soutschek, Jürgen, Bhat, Balkrishen, Marcusson, Eric G, Teruya-Feldstein, Julie, Bell, George W

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Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy von Woo, Caroline J., Maier, Verena K., Davey, Roshni, Brennan, James, Li, Guangde, Brothers, John, Schwartz, Brian, Gordo, Susana, Kasper, Anne, Okamoto, Trevor R., Johansson, Hans E., Mandefro, Berhan, Sareen, Dhruv, Bialek, Peter, Chau, B. Nelson, Bhat, Balkrishen, Bullough, David, Barsoum, James

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Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit von Bertero, Thomas, Cottrill, Katherine A., Lu, Yu, Haeger, Christina M., Dieffenbach, Paul, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Kaimal, Vivek, Zhang, Ying-Yi, Graham, Brian B., Kumar, Rahul, Saggar, Rajan, Saggar, Rajeev, Wallace, W. Dean, Ross, David J., Black, Stephen M., Fratz, Sohrab, Fineman, Jeffrey R., Vargas, Sara O., Haley, Kathleen J., Waxman, Aaron B., Chau, B. Nelson, Fredenburgh, Laura E., Chan, Stephen Y.

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Comparison of different miR-21 inhibitor chemistries in a cardiac disease model von Thum, Thomas, Chau, Nelson, Bhat, Balkrishen, Gupta, Shashi Kumar, Linsley, Peter S, Bauersachs, Johann, Engelhardt, Stefan

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Potent inhibition of microRNA in vivo without degradation von Davis, Scott, Propp, Stephanie, Freier, Susan M, Jones, Laura E, Serra, Martin J, Kinberger, Garth, Bhat, Balkrishen, Swayze, Eric E, Bennett, C. Frank, Esau, Christine

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Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension von Bertero, Thomas, Lu, Yu, Annis, Sofia, Hale, Andrew, Bhat, Balkrishen, Saggar, Rajan, Saggar, Rajeev, Wallace, W Dean, Ross, David J, Vargas, Sara O, Graham, Brian B, Kumar, Rahul, Black, Stephen M, Fratz, Sohrab, Fineman, Jeffrey R, West, James D, Haley, Kathleen J, Waxman, Aaron B, Chau, B Nelson, Cottrill, Katherine A, Chan, Stephen Y

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Anti-miRs competitively inhibit microRNAs in Argonaute complexes von Hogan, Daniel J, Vincent, Thomas M, Fish, Sarah, Marcusson, Eric G, Bhat, Balkrishen, Chau, B Nelson, Zisoulis, Dimitrios G

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Synthesis, Improved Antisense Activity and Structural Rationale for the Divergent RNA Affinities of 3′-Fluoro Hexitol Nucleic Acid (FHNA and Ara-FHNA) Modified Oligonucleotides von Egli, Martin, Pallan, Pradeep S, Allerson, Charles R, Prakash, Thazha P, Berdeja, Andres, Yu, Jinghua, Lee, Sam, Watt, Andrew, Gaus, Hans, Bhat, Balkrishen, Swayze, Eric E, Seth, Punit P

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Positional Effect of Chemical Modifications on Short Interference RNA Activity in Mammalian Cells von Prakash, Thazha P, Allerson, Charles R, Dande, Prasad, Vickers, Timothy A, Sioufi, Namir, Jarres, Russell, Baker, Brenda F, Swayze, Eric E, Griffey, Richard H, Bhat, Balkrishen

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Characterization of Resistance to Non-obligate Chain-terminating Ribonucleoside Analogs That Inhibit Hepatitis C Virus Replication in Vitro von Migliaccio, Giovanni, Tomassini, Joanne E., Carroll, Steven S., Tomei, Licia, Altamura, Sergio, Bhat, Balkrishen, Bartholomew, Linda, Bosserman, Michele R., Ceccacci, Alessandra, Colwell, Lawrence F., Cortese, Riccardo, De Francesco, Raffaele, Eldrup, Anne B., Getty, Krista L., Hou, Xiaoli S., LaFemina, Robert L., Ludmerer, Steven W., MacCoss, Malcolm, McMasters, Daniel R., Stahlhut, Mark W., Olsen, David B., Hazuda, Daria J., Flores, Osvaldo A.

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Competition for RISC binding predicts in vitro potency of siRNA von Koller, Erich, Propp, Stephanie, Murray, Heather, Lima, Walter, Bhat, Balkrishen, Prakash, Thaza P, Allerson, Charles R, Swayze, Eric E, Marcusson, Eric G, Dean, Nicholas M

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Structure−Activity Relationship of Purine Ribonucleosides for Inhibition of Hepatitis C Virus RNA-Dependent RNA Polymerase von Eldrup, Anne B, Allerson, Charles R, Bennett, C. Frank, Bera, Sanjib, Bhat, Balkrishen, Bhat, Neelima, Bosserman, Michele R, Brooks, Jennifer, Burlein, Christine, Carroll, Steven S, Cook, P. Dan, Getty, Krista L, MacCoss, Malcolm, McMasters, Daniel R, Olsen, David B, Prakash, Thazha P, Prhavc, Marija, Song, Quanlai, Tomassini, Joanne E, Xia, Jie

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Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs von Carroll, Steven S, Tomassini, Joanne E, Bosserman, Michele, Getty, Krista, Stahlhut, Mark W, Eldrup, Anne B, Bhat, Balkrishen, Hall, Dawn, Simcoe, Amy L, LaFemina, Robert, Rutkowski, Carrie A, Wolanski, Bohdan, Yang, Zhucheng, Migliaccio, Giovanni, De Francesco, Raffaele, Kuo, Lawrence C, MacCoss, Malcolm, Olsen, David B

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A 7-Deaza-Adenosine Analog Is a Potent and Selective Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic Properties von OLSEN, David B, ELDRUP, Anne B, GROBLER, Jay A, LAFEMINA, Robert L, MARKEL, Eric J, MIGLIACCIO, Giovanni, PRHAVC, Marija, STAHLHUT, Mark W, TOMASSINI, Joanne E, MACCOSS, Malcolm, HAZUDA, Daria J, CARROLL, Steven S, BARTHOLOMEW, Linda, BHAT, Balkrishen, BOSSERMAN, Michele R, CECCACCI, Alessandra, COLWELL, Lawrence F, FAY, John F, FLORES, Osvaldo A, GETTY, Krista L

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Configuration of the 5′-Methyl Group Modulates the Biophysical and Biological Properties of Locked Nucleic Acid (LNA) Oligonucleotides von Seth, Punit P, Allerson, Charles R, Siwkowski, Andrew, Vasquez, Guillermo, Berdeja, Andres, Migawa, Michael T, Gaus, Hans, Prakash, Thazha P, Bhat, Balkrishen, Swayze, Eric E

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Structure Activity Relationships of α-L-LNA Modified Phosphorothioate Gapmer Antisense Oligonucleotides in Animals von Seth, Punit P, Jazayeri, Ali, Yu, Jeff, Allerson, Charles R, Bhat, Balkrishen, Swayze, Eric E

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mRNA therapeutics: beyond vaccine applications von Bhat, Balkrishen, Karve, Shrirang, Anderson, Daniel G.

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Comparing In Vitro and In Vivo Activity of 2′-O-[2-(Methylamino)-2-oxoethyl]- and 2′-O-Methoxyethyl-Modified Antisense Oligonucleotides von Prakash, Thazha P, Kawasaki, Andrew M, Wancewicz, Edward V, Shen, Lijiang, Monia, Brett P, Ross, Bruce S, Bhat, Balkrishen, Manoharan, Muthiah

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Systemic delivery of mRNA and DNA to the lung using polymer-lipid nanoparticles von Kaczmarek, James C., Patel, Asha Kumari, Rhym, Luke H., Palmiero, Umberto Capasso, Bhat, Balkrishen, Heartlein, Michael W., DeRosa, Frank, Anderson, Daniel G.

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Structural Requirements at the Catalytic Site of the Heteroduplex Substrate for Human RNase H1 Catalysis von Lima, Walt F, Nichols, Josh G, Wu, Hongjiang, Prakash, Thazha P, Migawa, Mike T, Wyrzykiewicz, Tadensz K, Bhat, Balkrishen, Crooke, Stanley T

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