Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core von Sivaprakasam, Prasanna, Han, Xiaojun, Civiello, Rita L, Jacutin-Porte, Swanee, Kish, Kevin, Pokross, Matt, Lewis, Hal A, Ahmed, Nazia, Szapiel, Nicolas, Newitt, John A, Baldwin, Eric T, Xiao, Hong, Krause, Carol M, Park, Hyunsoo, Nophsker, Michelle, Lippy, Jonathan S, Burton, Catherine R, Langley, David R, Macor, John E, Dubowchik, Gene M

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Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers von Gerritz, Samuel W, Cianci, Christopher, Kim, Sean, Pearce, Bradley C, Deminie, Carol, Discotto, Linda, McAuliffe, Brian, Minassian, Beatrice F, Shi, Shuhao, Zhu, Shirong, Zhai, Weixu, Pendri, Annapurna, Li, Guo, Poss, Michael A, Edavettal, Suzanne, McDonnell, Patricia A, Lewis, Hal A, Maskos, Klaus, Mörtl, Mario, Kiefersauer, Reiner, Steinbacher, Stefan, Baldwin, Eric T, Metzler, William, Bryson, James, Healy, Matthew D, Philip, Thomas, Zoeckler, Mary, Schartman, Richard, Sinz, Michael, Leyva-Grado, Victor H, Hoffmann, Hans-Heinrich, Langley, David R, Meanwell, Nicholas A, Krystal, Mark

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Crystal Structure of the Herpes Simplex Virus 1 DNA Polymerase von Liu, Shenping, Knafels, John D., Chang, Jeanne S., Waszak, Gregory A., Baldwin, Eric T., Deibel, Martin R., Thomsen, Darrell R., Homa, Fred L., Wells, Peter A., Tory, Monica C., Poorman, Roger A., Gao, Hua, Qiu, Xiayang, Seddon, Andrew P.

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Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhib... von Baldwin, Eric T, Götte, Matthias, Tchesnokov, Egor P, Arnold, Eddy, Hagel, Margit, Nichols, Charles, Dossang, Pam, Lamers, Marieke, Wan, Paul, Steinbacher, Stefan, Romero, Donna L

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Structures, functions and adaptations of the human LINE-1 ORF2 protein von Baldwin, Eric T., van Eeuwen, Trevor, Hoyos, David, Zalevsky, Arthur, Tchesnokov, Egor P., Sánchez, Roberto, Miller, Bryant D., Di Stefano, Luciano H., Ruiz, Francesc Xavier, Hancock, Matthew, Işik, Esin, Mendez-Dorantes, Carlos, Walpole, Thomas, Nichols, Charles, Wan, Paul, Riento, Kirsi, Halls-Kass, Rowan, Augustin, Martin, Lammens, Alfred, Jestel, Anja, Upla, Paula, Xibinaku, Kera, Congreve, Samantha, Hennink, Maximiliaan, Rogala, Kacper B., Schneider, Anna M., Fairman, Jennifer E., Christensen, Shawn M., Desrosiers, Brian, Bisacchi, Gregory S., Saunders, Oliver L., Hafeez, Nafeeza, Miao, Wenyan, Kapeller, Rosana, Zaller, Dennis M., Sali, Andrej, Weichenrieder, Oliver, Burns, Kathleen H., Götte, Matthias, Rout, Michael P., Arnold, Eddy, Greenbaum, Benjamin D., Romero, Donna L., LaCava, John, Taylor, Martin S.

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Metrics and the effective computational scientist: process, quality and communication von Baldwin, Eric T.

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Developing Adnectins That Target SRC Co-Activator Binding to PXR: A Structural Approach toward Understanding Promiscuity of PXR von Khan, Javed A., Camac, Daniel M., Low, Simon, Tebben, Andrew J., Wensel, David L., Wright, Martin C., Su, Julie, Jenny, Victoria, Gupta, Ruchira Das, Ruzanov, Max, Russo, Katie A., Bell, Aneka, An, Yongmi, Bryson, James W., Gao, Mian, Gambhire, Pallavi, Baldwin, Eric T., Gardner, Daniel, Cavallaro, Cullen L., Duncia, John V., Hynes, John

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Crystal Structure of Type II Peptide Deformylase from Staphylococcus aureus von Baldwin, Eric T, Harris, Melissa S, Yem, Anthony W, Wolfe, Cindy L, Vosters, Anne F, Curry, Kimberly A, Murray, Robert W, Bock, Jeffrey H, Marshall, Vincent P, Cialdella, Joyce I, Merchant, Mahesh H, Choi, Gil, Deibel, Jr, Martin R

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Ligand placement based on prior structures: the guided ligand-replacement method von Klei, Herbert E., Moriarty, Nigel W., Echols, Nathaniel, Terwilliger, Thomas C., Baldwin, Eric T., Pokross, Matt, Posy, Shana, Adams, Paul D.

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A Structural Variation for MurB:  X-ray Crystal Structure of Staphylococcus aureus UDP-N-Acetylenolpyruvylglucosamine Reductase (MurB) von Benson, Timothy E, Harris, Melissa S, Choi, Gil H, Cialdella, Joyce I, Herberg, John T, Martin, Joseph P, Baldwin, Eric T

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Structural basis of drug resistance for the V82A mutant of HIV-1 proteinase von Baldwin, Eric T, Bhat, T. Narayana, Liu, Beishan, Pattabiraman, Nagarajan, Erickson, John W

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Conserved Core Substructures in the Overlay of Protein–Ligand Complexes von Finzel, Barry C, Akavaram, Ramprasad, Ragipindi, Aravind, Van Voorst, Jeffrey R, Cahn, Matthew, Davis, Malcolm E, Pokross, Matt E, Sheriff, Steven, Baldwin, Eric T

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Physical methods to determine the binding mode of putative ligands for hepatitis C virus NS3 helicase von Sarver, Ronald W, Rogers, Joseph M, Stockman, Brian J, Epps, Dennis E, DeZwaan, Jack, Harris, Melissa S, Baldwin, Eric T

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Affinity purification of a chimeric nicotinic acetylcholine receptor in the agonist and antagonist bound states von Liu, Shenping, Babcock, Merrill S., Bode, Jacob, Chang, Jeanne S., Fischer, H. David, Garlick, Robert L., Gill, Gurnam S., Lund, Eric T., Margolis, Brandon J., Mathews, W. Rodney, Rogers, Bruce N., Wolfe, Mark, Groppi, Vince, Baldwin, Eric T.

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Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophenylnorstatine von Baldwin, Eric T, Bhat, T.Narayana, Gulnik, Sergei, Liu, Beishan, Topol, Igor A, Kiso, Yoshiaki, Mimoto, Tsutomu, Mitsuya, Hiroaki, Erickson, John W

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Influence of stereochemistry on activity and binding modes for C2 symmetry-based diol inhibitors of HIV-1 protease von Hosur, Madhusoodan V, Bhat, T. Narayana, Kempf, Dale J, Baldwin, Eric T, Liu, Beishan, Gulnik, Sergei, Wideburg, Norman E, Norbeck, Daniel W, Appelt, Krzysztof, Erickson, John W

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Cation binding to the integrin CD11b I domain and activation model assessment von Baldwin, Eric T, Sarver, Ronald W, Bryant, Garold L, Curry, Kimberly A, Fairbanks, Michael B, Finzel, Barry C, Garlick, Robert L, Heinrikson, Robert L, Horton, Nancy C, Kelley, Laura-Lee C, Mildner, Ana M, Moon, Joseph B, Mott, John E, Mutchler, Veronica T, Tomich, Che-Shen C, Watenpaugh, Keith D, Wiley, Veronica H

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Identification of a Binding Site for the Human Immunodeficiency Virus Type 1 Nucleocapsid Protein von Sakaguchi, Kazuyasu, Zambrano, Nicola, Baldwin, Eric T., Shapiro, Bruce A., Erickson, John W., Omichinski, James G., Clore, G. Marius, Gronenborn, Angela M., Appella, Ettore

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Developing Adnectins That Target SRC Co-Activator Binding to PXR: A Structural Approach toward Understanding Promiscuity of PXR von Khan, Javed A., Camac, Daniel M., Low, Simon, Tebben, Andrew J., Wensel, David L., Wright, Martin C., Su, Julie, Jenny, Victoria, Gupta, Ruchira Das, Ruzanov, Max, Russo, Katie A., Bell, Aneka, An, Yongmi, Bryson, James W., Gao, Mian, Gambhire, Pallavi, Baldwin, Eric T., Gardner, Daniel, Cavallaro, Cullen L., Duncia, John V., Hynes, Jr., John

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4-Hydroxy-5,6-dihydropyrones. 2. Potent Non-Peptide Inhibitors of HIV Protease von Tait, Bradley D, Hagen, Susan, Domagala, John, Ellsworth, Edmund L, Gajda, Christopher, Hamilton, Harriet W, Vara Prasad, J. V. N, Ferguson, Donna, Graham, Neil, Hupe, Donald, Nouhan, Carolyn, Tummino, Peter J, Humblet, Christine, Lunney, Elizabeth A, Pavlovsky, Alexander, Rubin, John, Gracheck, Stephen J, Baldwin, Eric T, Bhat, T. N, Erickson, John W, Gulnik, Sergei V, Liu, Beishan

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