Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and Systemically von Chafe, Shawn C, McDonald, Paul C, Saberi, Saeed, Nemirovsky, Oksana, Venkateswaran, Geetha, Burugu, Samantha, Gao, Dongxia, Delaidelli, Alberto, Kyle, Alastair H, Baker, Jennifer H E, Gillespie, Jordan A, Bashashati, Ali, Minchinton, Andrew I, Zhou, Youwen, Shah, Sohrab P, Dedhar, Shoukat

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Loss of the Notch effector RBPJ promotes tumorigenesis von Kulic, Iva, Robertson, Gordon, Chang, Linda, Baker, Jennifer H E, Lockwood, William W, Mok, Winnie, Fuller, Megan, Fournier, Michèle, Wong, Nelson, Chou, Vennie, Robinson, Mark D, Chun, Hye-Jung, Gilks, Blake, Kempkes, Bettina, Thomson, Thomas A, Hirst, Martin, Minchinton, Andrew I, Lam, Wan L, Jones, Steven, Marra, Marco, Karsan, Aly

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Direct Visualization of Heterogeneous Extravascular Distribution of Trastuzumab in Human Epidermal Growth Factor Receptor Type 2 Overexpressing Xenografts von BAKER, Jennifer H. E, LINDQUIST, Kirstin E, HUXHAM, Lynsey A, KYLE, Alastair H, SY, Jonathan T, MINCHINTON, Andrew I

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Targeting Quiescent Tumor Cells via Oxygen and IGF-I Supplementation von KYLE, Alastair H, BAKER, Jennifer H. E, MINCHINTON, Andrew I

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Hyperbranched Polyglycerols as Trimodal Imaging Agents: Design, Biocompatibility, and Tumor Uptake von Saatchi, Katayoun, Soema, Peter, Gelder, Nikolaus, Misri, Ripen, McPhee, Kelly, Baker, Jennifer H.E, Reinsberg, Stefan A, Brooks, Donald E, Häfeli, Urs O

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Tissue uptake of docetaxel loaded hydrophobically derivatized hyperbranched polyglycerols and their effects on the morphology of the bladder urothelium von Mugabe, Clement, Raven, Peter A, Fazli, Ladan, Baker, Jennifer H.E, Jackson, John K, Liggins, Richard T, So, Alan I, Gleave, Martin E, Minchinton, Andrew I, Brooks, Donald E, Burt, Helen M

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Irinophore C, a Novel Nanoformulation of Irinotecan, Alters Tumor Vascular Function and Enhances the Distribution of 5-Fluorouracil and Doxorubicin von BAKER, Jennifer H. E, LAM, Jeffrey, ADAM, Michael J, YUNG, Andrew, KOZLOWSKI, Piotr, MINCHINTON, Andrew I, NG, Sylvia S. W, BALLY, Marcel B, YAPP, Donald T. T, KYLE, Alaistair H, SY, Jonathan, OLIVER, Thomas, CO, Steven J, DRAGOWSKA, Wieslawa H, RAMSAY, Euan, ANANTHA, Malathi, RUTH, Thomas J

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Detecting Vascular-Targeting Effects of the Hypoxic Cytotoxin Tirapazamine in Tumor Xenografts Using Magnetic Resonance Imaging von Bains, Lauren J., M.Sc, Baker, Jennifer H.E., B.Sc, Kyle, Alastair H., Ph.D, Minchinton, Andrew I., Ph.D, Reinsberg, Stefan A., Ph.D

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DNA-PK inhibition extends the therapeutic effects of Top2 poisoning to non-proliferating cells, increasing activity at a cost von Wang, Taixiang, Kyle, Alastair H., Baker, Jennifer H. E., Liu, Nannan A., Banáth, Judit P., Minchinton, Andrew I.

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Detection of FLASH-radiotherapy tissue sparing in a 3D-spheroid model using DNA damage response markers von Kyle, Alastair H., Karan, Tania, Baker, Jennifer H.E., Püspöky Banáth, Judit, Wang, Taixiang, Liu, Anam, Mendez, Claudia, Peter Petric, M., Duzenli, Cheryl, Minchinton, Andrew I.

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DNA-PK inhibitor AZD7648 is a more portent radiosensitizer than PARP inhibitor Olaparib in BRCA1/2 deficient tumors von Wang, Taixiang, Kyle, Alastair H., Baker, Jennifer H.E., Liu, Nannan A., Banáth, Judit P., Teymori, Sevin, Minchinton, Andrew I.

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Fast and sensitive dynamic oxygen‐enhanced MRI with a cycling gas challenge and independent component analysis von Moosvi, Firas, Baker, Jennifer H.E., Yung, Andrew, Kozlowski, Piotr, Minchinton, Andrew I., Reinsberg, Stefan A.

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Endothelial-Specific Notch Blockade Inhibits Vascular Function and Tumor Growth through an eNOS-Dependent Mechanism von PATENAUDE, Alexandre, FULLER, Megan, TONG, Jade, MINCHINTON, Andrew I, KARSAN, Aly, CHANG, Linda, WONG, Fred, PALIOURAS, Grigorios, SHAW, Rebecca, KYLE, Alastair H, UMLANDT, Patricia, BAKER, Jennifer H. E, DIAZ, Erika

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In vivo Evaluation of Mucoadhesive Nanoparticulate Docetaxel for Intravesical Treatment of Non―Muscle-Invasive Bladder Cancer von MUGABE, Clement, MATSUI, Yoshiyuki, SO, Alan I, GLEAVE, Martin E, BAKER, Jennifer H. E, MINCHINTON, Andrew I, MANISALI, Irina, LIGGINS, Richard, BROOKS, Donald E, BURT, Helen M

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Abstract A110: Hypoxia-selective DNA-PK inhibitor von Kyle, Alastair H., Baker, Jennifer H.E., Fryer, Karen H., Banaáth, Judit, Wang, Taixiang, Porres, Soraya S., Mann, Sam E., Hynd, George, Menear, Keith, Minchinton, Andrew I.

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Abstract B32: Microenvironmental distribution of trastuzumab in metastases and xenograft models is highly heterogeneous and decreases sharply when administered in combination with... von Baker, Jennifer H.E., Kyle, Alastair H., Cran, Jordan, Patrick, Haley, Gandolfo, Maria-Jose, Minchinton, Andrew I.

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Tissue penetration and activity of camptothecins in solid tumor xenografts von Kyle, Alastair H, Baker, Jennifer H E, Gandolfo, Maria-Jose, Reinsberg, Stefan A, Minchinton, Andrew I

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Abstract 827: Camptothecins: Tissue penetration and implications for therapy von Kyle, Alastair H., Gandolfo, Maria Jose, Baker, Jennifer H.E., Minchinton, Andrew I.

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Targeting the tumour vasculature: exploitation of low oxygenation and sensitivity to NOS inhibition by treatment with a hypoxic cytotoxin von Baker, Jennifer H E, Kyle, Alastair H, Bartels, Kirsten L, Methot, Stephen P, Flanagan, Erin J, Balbirnie, Andrew, Cran, Jordan D, Minchinton, Andrew I

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Opposing roles for CD34 in B16 melanoma tumor growth alter early stage vasculature and late stage immune cell infiltration von Maltby, Steven, Freeman, Spencer, Gold, Matthew J, Baker, Jennifer H E, Minchinton, Andrew I, Gold, Michael R, Roskelley, Calvin D, McNagny, Kelly M

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