Self-renewal as a therapeutic target in human colorectal cancer von Kreso, Antonija, van Galen, Peter, Pedley, Nicholas M, Lima-Fernandes, Evelyne, Frelin, Catherine, Davis, Thomas, Cao, Liangxian, Baiazitov, Ramil, Du, Wu, Sydorenko, Nadiya, Moon, Young-Choon, Gibson, Lianne, Wang, Yadong, Leung, Cherry, Iscove, Norman N, Arrowsmith, Cheryl H, Szentgyorgyi, Eva, Gallinger, Steven, Dick, John E, O'Brien, Catherine A

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Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer von Dey, Anindya, Xiong, Xunhao, Crim, Aleia, Dwivedi, Shailendra Kumar Dhar, Mustafi, Soumyajit Banerjee, Mukherjee, Priyabrata, Cao, Liangxian, Sydorenko, Nadiya, Baiazitov, Ramil, Moon, Young-Choon, Dumble, Melissa, Davis, Thomas, Bhattacharya, Resham

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Chemical modifications of G418 (geneticin): Synthesis of novel readthrough aminoglycosides results in an improved in vitro safety window but no improvements in vivo von Baiazitov, Ramil Y., Friesen, Westley, Johnson, Briana, Mollin, Anna, Sheedy, Josephine, Sierra, Jairo, Weetall, Marla, Branstrom, Arthur, Welch, Ellen, Moon, Young-Choon

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SAR studies toward discovery of emvododstat (PTC299), a potent dihydroorotate dehydrogenase (DHODH) inhibitor von Baiazitov, Ramil Y., Qi, Hongyan, Arasu, Tamil, Lennox, William, Cao, Liangxian, Weetall, Marla, Furia, Bansri, Zhuo, Jin, Choi, Soongyu, Kim, Min Jung, Sheedy, Josephine, Davis, Thomas, Moon, Young-Choon

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Unexpected Observation of the Dimroth Rearrangement in the Ribosylation of 4‑Aminopyrimidines von Baiazitov, Ramil Y, Sydorenko, Nadiya, Ren, Hongyu, Moon, Young-Choon

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Guanidino quinazolines and pyrimidines promote readthrough of premature termination codons in cells with native nonsense mutations von Morrill, Christie, Friesen, Westley J., Babu, Suresh, Baiazitov, Ramil Y., Du, Wu, Karloff, Diane B., Lee, Chang-Sun, Moon, Young-Choon, Ren, Hongyu, Sierra, Jairo, Tomizawa, Yuki, Vazirani, Priya, Welch, Ellen M., Xue, Xiaojiao, Zhuo, Jin

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Discovery and SAR Studies of Potent Modulators of BMI‐1 Expression von Baiazitov, Ramil Y., Sydorenko, Nadiya, Du, Wu, Ren, Hongyu, Cao, Liang, Davis, Thomas, Cintron‐Lue, Katherine, Kim, Min‐Jung, Zhuo, Jin, Mody, Shreshtha, Weetall, Marla, Sheedy, Josephine, Risher, Nicole, Almstead, Neil, Moon, Young‐Choon

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Tandem Double-Intramolecular [4+2]/[3+2] Cycloadditions of Nitroalkenes. Studies toward a Total Synthesis of Daphnilactone B:  Piperidine Ring Construction von Denmark, Scott E, Baiazitov, Ramil Y

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The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential von Friesen, Westley J, Johnson, Briana, Sierra, Jairo, Zhuo, Jin, Vazirani, Priya, Xue, Xiaojiao, Tomizawa, Yuki, Baiazitov, Ramil, Morrill, Christie, Ren, Hongyu, Babu, Suresh, Moon, Young-Choon, Branstrom, Art, Mollin, Anna, Hedrick, Jean, Sheedy, Josephine, Elfring, Gary, Weetall, Marla, Colacino, Joseph M, Welch, Ellen M, Peltz, Stuart W

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Tandem double intramolecular [4+2]/[3+2] cycloadditions of nitroalkenes: construction of the pentacyclic core structure of daphnilactone B von Denmark, Scott E., Baiazitov, Ramil Y., Nguyen, Son T.

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Abstract 5517: PTC596-induced Bmi1 hyper-phosphorylation via Cdk1/2 activation resulting in tumor stem cell depletion von Kim, Min Jung, Cao, Liangxian, Sheedy, Josephine, Risher, Nicole, Dumble, Melissa, Lee, Chang-Sun, Sydorenko, Nadiya, Baiazitov, Ramil, Du, Wu, Moon, Young-Choon, Weetall, Marla L., Colacino, Joseph, Davis, Thomas W.

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Intramolecular [4 + 2] Cycloaddition of Nitroalkenes for Construction of Vicinal Quaternary Stereocenters von Denmark, Scott E, Baiazitov, Ramil Y

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Synthesis and Reactions of Trifluoromethyl‐Substituted 1,3,5‐Triazines von Jeon, Woohyung, Baiazitov, Ramil, Chierchia, Matteo, Niederer, Kyle, Ren, Hongyu, Moon, Young‐Choon, Gilbert, Bradley B.

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The nucleoside analog clitocine is a potent and efficacious readthrough agent von Friesen, Westley J, Trotta, Christopher R, Tomizawa, Yuki, Zhuo, Jin, Johnson, Briana, Sierra, Jairo, Roy, Bijoyita, Weetall, Marla, Hedrick, Jean, Sheedy, Josephine, Takasugi, James, Moon, Young-Choon, Babu, Suresh, Baiazitov, Ramil, Leszyk, John D, Davis, Thomas W, Colacino, Joseph M, Peltz, Stuart W, Welch, Ellen M

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BMI1 is a therapeutic target in recurrent medulloblastoma von Bakhshinyan, David, Venugopal, Chitra, Adile, Ashley A., Garg, Neha, Manoranjan, Branavan, Hallett, Robin, Wang, Xin, Mahendram, Sujeivan, Vora, Parvez, Vijayakumar, Thusyanth, Subapanditha, Minomi, Singh, Mohini, Kameda-Smith, Michelle Masayo, Qazi, Maleeha, McFarlane, Nicole, Mann, Aneet, Ajani, Olufemi A., Yarascavitch, Blake, Ramaswamy, Vijay, Farooq, Hamza, Morrissy, Sorana, Cao, Liangxian, Sydorenko, Nadiya, Baiazitov, Ramil, Du, Wu, Sheedy, Josephine, Weetall, Marla, Moon, Young-Choon, Lee, Chang-Sun, Kwiecien, Jacek M., Delaney, Kathleen H., Doble, Brad, Cho, Yoon-Jae, Mitra, Siddhartha, Kaplan, David, Taylor, Michael D., Davis, Thomas W., Singh, Sheila K.

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Abstract 2529: Optimization of small molecules targeting BMI1 protein expression. Part 1. Amino-thiazoles: the first-in-class highly potent inhibitors of BMI1 protein von Sydorenko, Nadiya, Baiazitov, Ramil, Choi, Soongyu, Lee, Chang-Sun, Cao, Liangxian, Davis, Thomas W., Almstead, Neil G., Moon, Young-Choon

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Abstract 2528: Optimization of small molecules targeting BMI1 protein expression. Part 2. Improved potency, oral bioavailability, and in vivo efficacy of amino-pyrazines and amino-... von Baiazitov, Ramil, Sydorenko, Nadiya, Ren, Hongyu, Du, Wu, Paget, Steve, Wilde, Richard, Liu, Ronggang, Lee, Chang-Sun, Cao, Liangxian, Davis, Thomas W., Almstead, Neil G., Moon, Young-Choon

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Tandem double intramolecular [4+2]/[3+2] cycloadditions of nitroalkenes: construction of the pentacyclic core structure of daphnilactone B: 2008 Tetrahedron Prize for Creativity in... von DENMARK, Scott E, BAIAZITOV, Ramil Y, NGUYEN, Son T

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Tandem [4+2]/[3+2] Cycloadditions von Baiazitov, Ramil Y, Denmark, Scott E

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Use of an aminoglycoside for nonsense mutation suppression and the treatment of disease von BAIAZITOV Ramil Y

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