DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88 von Tarallo, Valeria, Hirano, Yoshio, Gelfand, Bradley D., Dridi, Sami, Kerur, Nagaraj, Kim, Younghee, Cho, Won Gil, Kaneko, Hiroki, Fowler, Benjamin J., Bogdanovich, Sasha, Albuquerque, Romulo J.C., Hauswirth, William W., Chiodo, Vince A., Kugel, Jennifer F., Goodrich, James A., Ponicsan, Steven L., Chaudhuri, Gautam, Murphy, Michael P., Dunaief, Joshua L., Ambati, Balamurali K., Ogura, Yuichiro, Yoo, Jae Wook, Lee, Dong-ki, Provost, Patrick, Hinton, David R., Núñez, Gabriel, Baffi, Judit Z., Kleinman, Mark E., Ambati, Jayakrishna

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Drusen Complement Components C3a and C5a Promote Choroidal Neovascularization von Nozaki, Miho, Raisler, Brian J., Sakurai, Eiji, Sarma, J. Vidya, Barnum, Scott R., Lambris, John D., Chen, Yali, Zhang, Kang, Ambati, Balamurali K., Baffi, Judit Z., Ambati, Jayakrishna

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Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth von Dridi, Sami, Hirashima, Masanori, Albuquerque, Romulo J C, Cho, Won Gil, Kleinman, Mark E, Capoor, Seema, Baffi, Judit Z, Peterson, Martha L, Kaneko, Hiroki, Amano, Shiro, Chappell, Joe, Wilting, Jörg, Ambati, Jayakrishna, Takeda, Atsunobu, Yamada, Kiyoshi, Mizuki, Nobuhisa, Weich, Herbert A, Green, Martha G, Ambati, Balamurali K, Alexander, Jonathan S, Usui, Tomohiko, Brekken, Rolf A, Yamagami, Satoru, Hayashi, Takahiko

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CCR3 is a target for age-related macular degeneration diagnosis and therapy von Ambati, Jayakrishna, Takeda, Atsunobu, Baffi, Judit Z, Kleinman, Mark E, Cho, Won Gil, Nozaki, Miho, Yamada, Kiyoshi, Kaneko, Hiroki, Albuquerque, Romulo J. C, Dridi, Sami, Saito, Kuniharu, Raisler, Brian J, Budd, Steven J, Geisen, Pete, Munitz, Ariel, Ambati, Balamurali K, Green, Martha G, Ishibashi, Tatsuro, Wright, John D, Humbles, Alison A, Gerard, Craig J, Ogura, Yuichiro, Pan, Yuzhen, Smith, Justine R, Grisanti, Salvatore, Hartnett, M. Elizabeth, Rothenberg, Marc E

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ERK1/2 activation is a therapeutic target in age-related macular degeneration von Dridi, Sami, Hirano, Yoshio, Tarallo, Valeria, Kim, Younghee, Fowler, Benjamin J, Ambati, Balamurali K, Bogdanovich, Sasha, Chiodo, Vince A, Hauswirth, William W, Kugel, Jennifer F, Goodrich, James A, Ponicsan, Steven L, Hinton, David R, Kleinman, Mark E, Baffi, Judit Z, Gelfand, Bradley D, Ambati, Jayakrishna

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Short-interfering RNAs Induce Retinal Degeneration via TLR3 and IRF3 von Kleinman, Mark E, Kaneko, Hiroki, Cho, Won Gil, Dridi, Sami, Fowler, Benjamin J, Blandford, Alexander D, Albuquerque, Romulo JC, Hirano, Yoshio, Terasaki, Hiroko, Kondo, Mineo, Fujita, Takashi, Ambati, Balamurali K, Tarallo, Valeria, Gelfand, Bradley D, Bogdanovich, Sasha, Baffi, Judit Z, Ambati, Jayakrishna

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Small Interfering RNA-Induced TLR3 Activation Inhibits Blood and Lymphatic Vessel Growth von Cho, Won Gil, Albuquerque, Romulo J. C., Kleinman, Mark E., Tarallo, Valeria, Greco, Adelaide, Nozaki, Miho, Green, Martha G., Baffi, Judit Z., Ambati, Balamurali K., De Falco, Massimo, Alexander, Jonathan S., Brunetti, Arturo, De Falco, Sandro, Ambati, Jayakrishna, Ferrara, Napoleone

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Sequence- and target-independent angiogenesis suppression by siRNA via TLR3 von Ambati, Jayakrishna, Kleinman, Mark E, Yamada, Kiyoshi, Takeda, Atsunobu, Chandrasekaran, Vasu, Nozaki, Miho, Baffi, Judit Z, Albuquerque, Romulo J. C, Yamasaki, Satoshi, Itaya, Masahiro, Pan, Yuzhen, Appukuttan, Binoy, Gibbs, Daniel, Yang, Zhenglin, Karikó, Katalin, Ambati, Balamurali K, Wilgus, Traci A, DiPietro, Luisa A, Sakurai, Eiji, Zhang, Kang, Smith, Justine R, Taylor, Ethan W

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DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration von Kaneko, Hiroki, Dridi, Sami, Tarallo, Valeria, Gelfand, Bradley D., Fowler, Benjamin J., Cho, Won Gil, Kleinman, Mark E., Ponicsan, Steven L., Hauswirth, William W., Chiodo, Vince A., Karikó, Katalin, Yoo, Jae Wook, Lee, Dong-ki, Hadziahmetovic, Majda, Song, Ying, Misra, Smita, Chaudhuri, Gautam, Buaas, Frank W., Braun, Robert E., Hinton, David R., Zhang, Qing, Grossniklaus, Hans E., Provis, Jan M., Madigan, Michele C., Milam, Ann H., Justice, Nikki L., Albuquerque, Romulo J. C., Blandford, Alexander D., Bogdanovich, Sasha, Hirano, Yoshio, Witta, Jassir, Fuchs, Elaine, Littman, Dan R., Ambati, Balamurali K., Rudin, Charles M., Chong, Mark M. W., Provost, Patrick, Kugel, Jennifer F., Goodrich, James A., Dunaief, Joshua L., Baffi, Judit Z., Ambati, Jayakrishna

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Human IgG1 antibodies suppress angiogenesis in a target-independent manner von Bogdanovich, Sasha, Kim, Younghee, Mizutani, Takeshi, Yasuma, Reo, Tudisco, Laura, Cicatiello, Valeria, Bastos-Carvalho, Ana, Kerur, Nagaraj, Hirano, Yoshio, Baffi, Judit Z, Tarallo, Valeria, Li, Shengjian, Yasuma, Tetsuhiro, Arpitha, Parthasarathy, Fowler, Benjamin J, Wright, Charles B, Apicella, Ivana, Greco, Adelaide, Brunetti, Arturo, Ruvo, Menotti, Sandomenico, Annamaria, Nozaki, Miho, Ijima, Ryo, Kaneko, Hiroki, Ogura, Yuichiro, Terasaki, Hiroko, Ambati, Balamurali K, Leusen, Jeanette HW, Langdon, Wallace Y, Clark, Michael R, Armour, Kathryn L, Bruhns, Pierre, Verbeek, J Sjef, Gelfand, Bradley D, De Falco, Sandro, Ambati, Jayakrishna

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Evaluation of extended release brimonidine intravitreal device in normotensive rabbit eyes von Deokule, Sunil P., Baffi, Judit Z., Guo, Hong, Nazzaro, Marty, Kaneko, Hiroki

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Corneal avascularity is due to soluble VEGF receptor-1 von Collinson, J. Martin, Shibuya, Masabumi, Baffi, Judit Z, Albuquerque, Romulo J. C, Newcomb, Michael T, Samuelson, Don A, Jani, Pooja D, Suthar, Tushar, Sakurai, Eiji, Ambati, Balamurali K, Raisler, Brian J, Bogdanovich, Sasha, Witta, Jassir, Agnew, Dalen W, Khurana, Tejvir S, Singh, Nirbhai, Curiel, David T, Ogura, Yuichiro, Richter, Elizabeth, Marsh, Helene, Baldwin, Megan E, Kwan, Donna, Nozaki, Miho, Green, W. Richard, Caldwell, Ruth B, Lin, Qing, Mahasreshti, Parameshwar J, Ikeda, Sakae, Ambati, Jayakrishna, St. Leger, Judy, Leiper, Lucy J, De Falco, Sandro, Takeda, Atsunobu, Kleinman, Mark E, Gerber, Hans-Peter, Ferrara, Napoleone, Orecchia, Angela

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The Multifactorial Nature of Retinal Vascular Disease von Kleinman, Mark E., Baffi, Judit Z., Ambati, Jayakrishna

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Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A von Nozaki, Miho, Sakurai, Eiji, Raisler, Brian J, Baffi, Judit Z, Witta, Jassir, Ogura, Yuichiro, Brekken, Rolf A, Sage, E Helene, Ambati, Balamurali K, Ambati, Jayakrishna

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Recruitment of marrow-derived endothelial cells to experimental choroidal neovascularization by local expression of vascular endothelial growth factor von Csaky, Karl G., Baffi, Judit Z., Byrnes, Gordon A., Wolfe, Jeremy D., Hilmer, Sara C., Flippin, Jessica, Cousins, Scott W.

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Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A von Nozaki, M.

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Nuclear Envelope Budding Enables Large Ribonucleoprotein Particle Export during Synaptic Wnt Signaling von Speese, Sean D., Ashley, James, Jokhi, Vahbiz, Nunnari, John, Barria, Romina, Li, Yihang, Ataman, Bulent, Koon, Alex, Chang, Young-Tae, Li, Qian, Moore, Melissa J., Budnik, Vivian

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Alternatively spliced VEGF receptor-2 is an essential endogenous inhibitor of lymphatic vessels von Albuquerque, Romulo J.C., Hayashi, Takahiko, Cho, Won Gil, Kleinman, Mark E., Dridi, Sami, Takeda, Atsunobu, Baffi, Judit Z., Yamada, Kiyoshi, Kaneko, Hiroki, Green, Martha G., Chappell, Joe, Wilting, Jörg, Weich, Herbert A., Yamagami, Satoru, Amano, Shiro, Mizuki, Nobuhisa, Alexander, Jonathan S., Peterson, Martha L., Brekken, Rolf A., Hirashima, Masanori, Capoor, Seema, Usui, Tomohiko, Ambati, Balamurali K., Ambati, Jayakrishna

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Human IgG1 antibodies suppress angiogenesis in a target-independent manner von Bogdanovich, Sasha, Kim, Younghee, Mizutani, Takeshi, Yasuma, Reo, Tudisco, Laura, Cicatiello, Valeria, Bastos-Carvalho, Ana, Kerur, Nagaraj, Hirano, Yoshio, Baffi, Judit Z, Tarallo, Valeria, Li, Shengjian, Yasuma, Tetsuhiro, Arpitha, Parthasarathy, Fowler, Benjamin J, Wright, Charles B, Apicella, Ivana, Greco, Adelaide, Brunetti, Arturo, Ruvo, Menotti, Sandomenico, Annamaria, Nozaki, Miho, Ijima, Ryo, Kaneko, Hiroki, Ogura, Yuichiro, Terasaki, Hiroko, Ambati, Balamurali K, Leusen, Jeanette HW, Langdon, Wallace Y, Clark, Michael R, Armour, Kathryn L, Bruhns, Pierre, Verbeek, J Sjef, Gelfand, Bradley D, De Falco, Sandro, Ambati, Jayakrishna

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CCR3 is a therapeutic and diagnostic target for neovascular age-related macular degeneration von Takeda, Atsunobu, Baffi, Judit Z., Kleinman, Mark E., Cho, Won Gil, Nozaki, Miho, Yamada, Kiyoshi, Kaneko, Hiroki, Albuquerque, Romulo J.C., Dridi, Sami, Saito, Kuniharu, Raisler, Brian J., Budd, Steven J., Geisen, Pete, Munitz, Ariel, Ambati, Balamurali K., Green, Martha G., Ishibashi, Tatsuro, Wright, John D., Humbles, Alison A., Gerard, Craig J., Ogura, Yuichiro, Pan, Yuzhen, Smith, Justine R., Grisanti, Salvatore, Hartnett, M. Elizabeth, Rothenberg, Marc E., Ambati, Jayakrishna

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