DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88 von Tarallo, Valeria, Hirano, Yoshio, Gelfand, Bradley D., Dridi, Sami, Kerur, Nagaraj, Kim, Younghee, Cho, Won Gil, Kaneko, Hiroki, Fowler, Benjamin J., Bogdanovich, Sasha, Albuquerque, Romulo J.C., Hauswirth, William W., Chiodo, Vince A., Kugel, Jennifer F., Goodrich, James A., Ponicsan, Steven L., Chaudhuri, Gautam, Murphy, Michael P., Dunaief, Joshua L., Ambati, Balamurali K., Ogura, Yuichiro, Yoo, Jae Wook, Lee, Dong-ki, Provost, Patrick, Hinton, David R., Núñez, Gabriel, Baffi, Judit Z., Kleinman, Mark E., Ambati, Jayakrishna

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Drusen Complement Components C3a and C5a Promote Choroidal Neovascularization von Nozaki, Miho, Raisler, Brian J., Sakurai, Eiji, Sarma, J. Vidya, Barnum, Scott R., Lambris, John D., Chen, Yali, Zhang, Kang, Ambati, Balamurali K., Baffi, Judit Z., Ambati, Jayakrishna

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Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth von Albuquerque, Romulo J C, Hayashi, Takahiko, Cho, Won Gil, Kleinman, Mark E, Dridi, Sami, Takeda, Atsunobu, Baffi, Judit Z, Yamada, Kiyoshi, Kaneko, Hiroki, Green, Martha G, Chappell, Joe, Wilting, Jörg, Weich, Herbert A, Yamagami, Satoru, Amano, Shiro, Mizuki, Nobuhisa, Alexander, Jonathan S, Peterson, Martha L, Brekken, Rolf A, Hirashima, Masanori, Capoor, Seema, Usui, Tomohiko, Ambati, Balamurali K, Ambati, Jayakrishna

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Sequence- and target-independent angiogenesis suppression by siRNA via TLR3 von Kleinman, Mark E., Yamada, Kiyoshi, Takeda, Atsunobu, Chandrasekaran, Vasu, Nozaki, Miho, Baffi, Judit Z., Albuquerque, Romulo J. C., Yamasaki, Satoshi, Itaya, Masahiro, Pan, Yuzhen, Appukuttan, Binoy, Gibbs, Daniel, Yang, Zhenglin, Karikó, Katalin, Ambati, Balamurali K., Wilgus, Traci A., DiPietro, Luisa A., Sakurai, Eiji, Zhang, Kang, Smith, Justine R., Taylor, Ethan W., Ambati, Jayakrishna

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DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration von Kaneko, Hiroki, Dridi, Sami, Tarallo, Valeria, Gelfand, Bradley D., Fowler, Benjamin J., Cho, Won Gil, Kleinman, Mark E., Ponicsan, Steven L., Hauswirth, William W., Chiodo, Vince A., Karikó, Katalin, Yoo, Jae Wook, Lee, Dong-ki, Hadziahmetovic, Majda, Song, Ying, Misra, Smita, Chaudhuri, Gautam, Buaas, Frank W., Braun, Robert E., Hinton, David R., Zhang, Qing, Grossniklaus, Hans E., Provis, Jan M., Madigan, Michele C., Milam, Ann H., Justice, Nikki L., Albuquerque, Romulo J. C., Blandford, Alexander D., Bogdanovich, Sasha, Hirano, Yoshio, Witta, Jassir, Fuchs, Elaine, Littman, Dan R., Ambati, Balamurali K., Rudin, Charles M., Chong, Mark M. W., Provost, Patrick, Kugel, Jennifer F., Goodrich, James A., Dunaief, Joshua L., Baffi, Judit Z., Ambati, Jayakrishna

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CCR3 is a target for age-related macular degeneration diagnosis and therapy von Takeda, Atsunobu, Baffi, Judit Z., Kleinman, Mark E., Cho, Won Gil, Nozaki, Miho, Yamada, Kiyoshi, Kaneko, Hiroki, Albuquerque, Romulo J. C., Dridi, Sami, Saito, Kuniharu, Raisler, Brian J., Budd, Steven J., Geisen, Pete, Munitz, Ariel, Ambati, Balamurali K., Green, Martha G., Ishibashi, Tatsuro, Wright, John D., Humbles, Alison A., Gerard, Craig J., Ogura, Yuichiro, Pan, Yuzhen, Smith, Justine R., Grisanti, Salvatore, Hartnett, M. Elizabeth, Rothenberg, Marc E., Ambati, Jayakrishna

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ERK1/2 activation is a therapeutic target in age-related macular degeneration von Dridi, Sami, Hirano, Yoshio, Tarallo, Valeria, Kim, Younghee, Fowler, Benjamin J, Ambati, Balamurali K, Bogdanovich, Sasha, Chiodo, Vince A, Hauswirth, William W, Kugel, Jennifer F, Goodrich, James A, Ponicsan, Steven L, Hinton, David R, Kleinman, Mark E, Baffi, Judit Z, Gelfand, Bradley D, Ambati, Jayakrishna

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Short-interfering RNAs Induce Retinal Degeneration via TLR3 and IRF3 von Kleinman, Mark E, Kaneko, Hiroki, Cho, Won Gil, Dridi, Sami, Fowler, Benjamin J, Blandford, Alexander D, Albuquerque, Romulo JC, Hirano, Yoshio, Terasaki, Hiroko, Kondo, Mineo, Fujita, Takashi, Ambati, Balamurali K, Tarallo, Valeria, Gelfand, Bradley D, Bogdanovich, Sasha, Baffi, Judit Z, Ambati, Jayakrishna

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Small Interfering RNA-Induced TLR3 Activation Inhibits Blood and Lymphatic Vessel Growth von Cho, Won Gil, Albuquerque, Romulo J. C., Kleinman, Mark E., Tarallo, Valeria, Greco, Adelaide, Nozaki, Miho, Green, Martha G., Baffi, Judit Z., Ambati, Balamurali K., De Falco, Massimo, Alexander, Jonathan S., Brunetti, Arturo, De Falco, Sandro, Ambati, Jayakrishna, Ferrara, Napoleone

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Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions von Lipecz, Agnes, Miller, Lauren, Kovacs, Illes, Czakó, Cecília, Csipo, Tamas, Baffi, Judit, Csiszar, Anna, Tarantini, Stefano, Ungvari, Zoltan, Yabluchanskiy, Andriy, Conley, Shannon

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Corneal avascularity is due to soluble VEGF receptor-1 von Ambati, Balamurali K., Nozaki, Miho, Singh, Nirbhai, Takeda, Atsunobu, Jani, Pooja D., Suthar, Tushar, Albuquerque, Romulo J. C., Richter, Elizabeth, Sakurai, Eiji, Newcomb, Michael T., Kleinman, Mark E., Caldwell, Ruth B., Lin, Qing, Ogura, Yuichiro, Orecchia, Angela, Samuelson, Don A., Agnew, Dalen W., St. Leger, Judy, Green, W. Richard, Mahasreshti, Parameshwar J., Curiel, David T., Kwan, Donna, Marsh, Helene, Ikeda, Sakae, Leiper, Lucy J., Collinson, J. Martin, Bogdanovich, Sasha, Khurana, Tejvir S., Shibuya, Masabumi, Baldwin, Megan E., Ferrara, Napoleone, Gerber, Hans-Peter, De Falco, Sandro, Witta, Jassir, Baffi, Judit Z., Raisler, Brian J., Ambati, Jayakrishna

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Targeted Intraceptor Nanoparticle Therapy Reduces Angiogenesis and Fibrosis in Primate and Murine Macular Degeneration von Luo, Ling, Zhang, Xiaohui, Hirano, Yoshio, Tyagi, Puneet, Barabás, Péter, Uehara, Hironori, Miya, Tadashi R, Singh, Nirbhai, Archer, Bonnie, Qazi, Yureeda, Jackman, Kyle, Das, Subrata K, Olsen, Thomas, Chennamaneni, Srinivas R, Stagg, Brian C, Ahmed, Faisal, Emerson, Lyska, Zygmunt, Kristen, Whitaker, Ross, Mamalis, Christina, Huang, Wei, Gao, Guangping, Srinivas, Sangly P, Krizaj, David, Baffi, Judit, Ambati, Jayakrishna, Kompella, Uday B, Ambati, Balamurali K

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Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1 von Luo, Ling, Uehara, Hironori, Zhang, Xiaohui, Das, Subrata K, Olsen, Thomas, Holt, Derick, Simonis, Jacquelyn M, Jackman, Kyle, Singh, Nirbhai, Miya, Tadashi R, Huang, Wei, Ahmed, Faisal, Bastos-Carvalho, Ana, Le, Yun Zheng, Mamalis, Christina, Chiodo, Vince A, Hauswirth, William W, Baffi, Judit, Lacal, Pedro M, Orecchia, Angela, Ferrara, Napoleone, Gao, Guangping, Young-Hee, Kim, Fu, Yingbin, Owen, Leah, Albuquerque, Romulo, Baehr, Wolfgang, Thomas, Kirk, Li, Dean Y, Chalam, Kakarla V, Shibuya, Masabumi, Grisanti, Salvatore, Wilson, David J, Ambati, Jayakrishna, Ambati, Balamurali K

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The Multifactorial Nature of Retinal Vascular Disease von Kleinman, Mark E., Baffi, Judit Z., Ambati, Jayakrishna

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Human IgG1 antibodies suppress angiogenesis in a target-independent manner von Bogdanovich, Sasha, Kim, Younghee, Mizutani, Takeshi, Yasuma, Reo, Tudisco, Laura, Cicatiello, Valeria, Bastos-Carvalho, Ana, Kerur, Nagaraj, Hirano, Yoshio, Baffi, Judit Z, Tarallo, Valeria, Li, Shengjian, Yasuma, Tetsuhiro, Arpitha, Parthasarathy, Fowler, Benjamin J, Wright, Charles B, Apicella, Ivana, Greco, Adelaide, Brunetti, Arturo, Ruvo, Menotti, Sandomenico, Annamaria, Nozaki, Miho, Ijima, Ryo, Kaneko, Hiroki, Ogura, Yuichiro, Terasaki, Hiroko, Ambati, Balamurali K, Leusen, Jeanette HW, Langdon, Wallace Y, Clark, Michael R, Armour, Kathryn L, Bruhns, Pierre, Verbeek, J Sjef, Gelfand, Bradley D, De Falco, Sandro, Ambati, Jayakrishna

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Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A von Nozaki, Miho, Sakurai, Eiji, Raisler, Brian J, Baffi, Judit Z, Witta, Jassir, Ogura, Yuichiro, Brekken, Rolf A, Sage, E Helene, Ambati, Balamurali K, Ambati, Jayakrishna

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Evaluation of extended release brimonidine intravitreal device in normotensive rabbit eyes von Deokule, Sunil P., Baffi, Judit Z., Guo, Hong, Nazzaro, Marty, Kaneko, Hiroki

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Survival of Retinal Pigment Epithelium after Exposure to Prolonged Oxidative Injury: A Detailed Gene Expression and Cellular Analysis von Strunnikova, Nataly, Zhang, Connie, Teichberg, Diane, Cousins, Scott W, Baffi, Judit, Becker, Kevin G, Csaky, Karl G

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Recruitment of marrow-derived endothelial cells to experimental choroidal neovascularization by local expression of vascular endothelial growth factor von Csaky, Karl G., Baffi, Judit Z., Byrnes, Gordon A., Wolfe, Jeremy D., Hilmer, Sara C., Flippin, Jessica, Cousins, Scott W.

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Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A von Nozaki, M.

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