Feeling Nature’s PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS) von Baell, Jonathan B

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Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017Utility and Limitations von Baell, Jonathan B, Nissink, J. Willem M

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FAF-Drugs3: a web server for compound property calculation and chemical library design von Lagorce, David, Sperandio, Olivier, Baell, Jonathan B, Miteva, Maria A, Villoutreix, Bruno O

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Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs von Dror, Ron O., Green, Hillary F., Valant, Celine, Borhani, David W., Valcourt, James R., Pan, Albert C., Arlow, Daniel H., Canals, Meritxell, Lane, J. Robert, Rahmani, Raphaël, Baell, Jonathan B., Sexton, Patrick M., Christopoulos, Arthur, Shaw, David E.

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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity von Liang, Shuwei, Tran, Eric, Du, Xin, Dong, Jiajun, Sudholz, Harrison, Chen, Hao, Qu, Zihan, Huntington, Nicholas D., Babon, Jeffrey J., Kershaw, Nadia J., Zhang, Zhong-Yin, Baell, Jonathan B., Wiede, Florian, Tiganis, Tony

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Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors von Dahlin, Jayme L., Nelson, Kathryn M., Strasser, Jessica M., Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena M., Organ, Shawna, Cuellar, Matthew, Singh, Gurpreet, Shrimp, Jonathan H., Nguyen, Nghi, Meier, Jordan L., Arrowsmith, Cheryl H., Brown, Peter J., Baell, Jonathan B., Walters, Michael A.

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Catalytic O-H bond insertion reactions using surface modified sewage sludge as a catalyst von Zhang, Zhipeng, Yu, Yang, Huang, Fei, Yi, Xiangyan, Xu, Yao, He, Yide, Baell, Jonathan B, Huang, He

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New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays von Baell, Jonathan B, Holloway, Georgina A

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Novel Perspectives on the Design and Development of a Long-Acting Subcutaneous Raltegravir Injection for Treatment of HIV-In Vitro and In Vivo Evaluation von Abd-Ellah, Heba S, Mudududdla, Ramesh, Carter, Glen P, Baell, Jonathan B

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GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity von Menon, Deepthi, Innes, Ashlee, Oakley, Aaron J., Dahlstrom, Jane E., Jensen, Lora M., Brüstle, Anne, Tummala, Padmaja, Rooke, Melissa, Casarotto, Marco G., Baell, Jonathan B., Nguyen, Nghi, Xie, Yiyue, Cuellar, Matthew, Strasser, Jessica, Dahlin, Jayme L., Walters, Michael A., Burgio, Gaetan, O’Neill, Luke A. J., Board, Philip G.

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Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign von Sykes, Melissa L, Baell, Jonathan B, Kaiser, Marcel, Chatelain, Eric, Moawad, Sarah R, Ganame, Danny, Ioset, Jean-Robert, Avery, Vicky M

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Design, Development, and Optimisation of Smart Linker Chemistry for Targeted Colonic Delivery-In Vitro Evaluation von Abd-Ellah, Heba S, Mudududdla, Ramesh, Carter, Glen P, Baell, Jonathan B

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Electrochemical Synthesis of Polysubstituted Sulfonated Pyrazoles via Cascade Intermolecular Condensation, Radical–Radical Cross Coupling Sulfonylation, and Pyrazole Annulation von Feng, Jiajun, Wang, Yuzhi, Gao, Luoyu, Yu, Yang, Baell, Jonathan B., Huang, Fei

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Broad Coverage of Commercially Available Lead-like Screening Space with Fewer than 350,000 Compounds von Baell, Jonathan B

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Correspondence: Reply to ‘Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury’ von Qin, Cheng Xue, May, Lauren T., Sexton, Patrick M., DeBono, Aaron J., Baell, Jonathan B., Christopoulos, Arthur, Ritchie, Rebecca H.

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Visible-Light-Induced Synthesis of 3‑Alkyl Chromones under Catalyst- and Additive-Free Conditions von Zhao, Wei, He, Zhiqin, Yang, Xiaohui, Yu, Yang, Baell, Jonathan B., Huang, Fei

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Photocatalytic Benzylic C–H Oxidation/Cyclization of Enaminones to the Synthesis of Polysubstituted Oxazoles von Li, Mingrui, He, Zhiqin, Zhao, Wei, Yu, Yang, Huang, Fei, Baell, Jonathan B.

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Screening-Based Translation of Public Research Encounters Painful Problems von Baell, Jonathan B

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Discovery of Potent and Selective Benzothiazole Hydrazone Inhibitors of Bcl‑XL von Sleebs, Brad E, Kersten, Wilhemus J. A, Kulasegaram, Sanji, Nikolakopoulos, George, Hatzis, Effie, Moss, Rebecca M, Parisot, John P, Yang, Hong, Czabotar, Peter E, Fairlie, W. Douglas, Lee, Erinna F, Adams, Jerry M, Chen, Lin, van Delft, Mark F, Lowes, Kym N, Wei, Andrew, Huang, David C.S, Colman, Peter M, Street, Ian P, Baell, Jonathan B, Watson, Keith, Lessene, Guillaume

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Copper‐Catalyzed Olefinic C(sp2)−H Activation/Carbene Insertion/Ester Hydrolysis/Cyclization with Aryl Diazo Esters for the Synthesis of Multisubstituted Furanones von Wang, Yuzhi, Yu, Yadong, Yu, Yang, Huang, Fei, Baell, Jonathan B.

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