Reduced Expression of MYC Increases Longevity and Enhances Healthspan von Hofmann, Jeffrey W., Zhao, Xiaoai, De Cecco, Marco, Peterson, Abigail L., Pagliaroli, Luca, Manivannan, Jayameenakshi, Hubbard, Gene B., Ikeno, Yuji, Zhang, Yongqing, Feng, Bin, Li, Xiaxi, Serre, Thomas, Qi, Wenbo, Van Remmen, Holly, Miller, Richard A., Bath, Kevin G., de Cabo, Rafael, Xu, Haiyan, Neretti, Nicola, Sedivy, John M.

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Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice von Mao, Kai, Quipildor, Gabriela Farias, Tabrizian, Tahmineh, Novaj, Ardijana, Guan, Fangxia, Walters, Ryan O., Delahaye, Fabien, Hubbard, Gene B., Ikeno, Yuji, Ejima, Keisuke, Li, Peng, Allison, David B., Salimi-Moosavi, Hossein, Beltran, Pedro J., Cohen, Pinchas, Barzilai, Nir, Huffman, Derek M.

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Does reduced IGF-1R signaling in Igf1r+/- mice alter aging? von Bokov, Alex F, Garg, Neha, Ikeno, Yuji, Thakur, Sachin, Musi, Nicolas, DeFronzo, Ralph A, Zhang, Ning, Erickson, Rebecca C, Gelfond, Jon, Hubbard, Gene B, Adamo, Martin L, Richardson, Arlan

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The paradoxical role of thioredoxin on oxidative stress and aging von Cunningham, Geneva M., Roman, Madeline G., Flores, Lisa C., Hubbard, Gene B., Salmon, Adam B., Zhang, Yiqiang, Gelfond, Jonathan, Ikeno, Yuji

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Reductions in serum IGF‐1 during aging impair health span von Gong, Zhenwei, Kennedy, Oran, Sun, Hui, Wu, YingJie, Williams, Garry A, Klein, Laura, Cardoso, Luis, Matheny, Ronald W., Hubbard, Gene B., Ikeno, Yuji, Farrar, Roger P., Schaffler, Mitchell B, Adamo, Martin L, Muzumdar, Radhika H, Yakar, Shoshana

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Pancreatic islet amyloidosis, β-cell apoptosis, and α-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons von Guardado-Mendoza, Rodolfo, Davalli, Alberto M, Chavez, Alberto O, Hubbard, Gene B, Dick, Edward J, Majluf-Cruz, Abraham, Tene-Perez, Carlos E, Goldschmidt, Lukasz, Hart, John, Perego, Carla, Comuzzie, Anthony G, Tejero, Maria Elizabeth, Finzi, Giovanna, Placidi, Claudia, La Rosa, Stefano, Capella, Carlo, Halff, Glenn, Gastaldelli, Amalia, DeFronzo, Ralph A, Folli, Franco

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Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice von List, Edward O, Berryman, Darlene E, Ikeno, Yuji, Hubbard, Gene B, Funk, Kevin, Comisford, Ross, Young, Jonathan A, Stout, Michael B, Tchkonia, Tamar, Masternak, Michal M, Bartke, Andrzej, Kirkland, James L, Miller, Richard A, Kopchick, John J

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Senolytics improve physical function and increase lifespan in old age von Xu, Ming, Pirtskhalava, Tamar, Farr, Joshua N., Weigand, Bettina M., Palmer, Allyson K., Weivoda, Megan M., Inman, Christina L., Ogrodnik, Mikolaj B., Hachfeld, Christine M., Fraser, Daniel G., Onken, Jennifer L., Johnson, Kurt O., Verzosa, Grace C., Langhi, Larissa G. P., Weigl, Moritz, Giorgadze, Nino, LeBrasseur, Nathan K., Miller, Jordan D., Jurk, Diana, Singh, Ravinder J., Allison, David B., Ejima, Keisuke, Hubbard, Gene B., Ikeno, Yuji, Cubro, Hajrunisa, Garovic, Vesna D., Hou, Xiaonan, Weroha, S. John, Robbins, Paul D., Niedernhofer, Laura J., Khosla, Sundeep, Tchkonia, Tamara, Kirkland, James L.

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Natural mortality and cause of death analysis of the captive chimpanzee (Pan troglodytes): A 35‐year review von Laurence, Hannah, Kumar, Shyamesh, Owston, Michael A., Lanford, Robert E., Hubbard, Gene B., Dick, Edward J.

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Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis von Camell, Christina D., Günther, Patrick, Lee, Aileen, Goldberg, Emily L., Spadaro, Olga, Youm, Yun-Hee, Bartke, Andrzej, Hubbard, Gene B., Ikeno, Yuji, Ruddle, Nancy H., Schultze, Joachim, Dixit, Vishwa Deep

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MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation von Laberge, Remi-Martin, Sun, Yu, Orjalo, Arturo V., Patil, Christopher K., Freund, Adam, Zhou, Lili, Curran, Samuel C., Davalos, Albert R., Wilson-Edell, Kathleen A., Liu, Su, Limbad, Chandani, Demaria, Marco, Li, Patrick, Hubbard, Gene B., Ikeno, Yuji, Javors, Martin, Desprez, Pierre-Yves, Benz, Christopher C., Kapahi, Pankaj, Nelson, Peter S., Campisi, Judith

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Cynomolgus macaques naturally infected with Trypanosoma cruzi-I exhibit an overall mixed pro-inflammatory/modulated cytokine signature characteristic of human Chagas disease von Vitelli-Avelar, Danielle Marquete, Sathler-Avelar, Renato, Mattoso-Barbosa, Armanda Moreira, Gouin, Nicolas, Perdigão-de-Oliveira, Marcelo, Valério-Dos-Reis, Leydiane, Costa, Ronaldo Peres, Elói-Santos, Silvana Maria, Gomes, Matheus de Souza, Amaral, Laurence Rodrigues do, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Dick, Jr, Edward J, Hubbard, Gene B, VandeBerg, Jane F, VandeBerg, John L

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The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs von Zhu, Yi, Tchkonia, Tamara, Pirtskhalava, Tamar, Gower, Adam C., Ding, Husheng, Giorgadze, Nino, Palmer, Allyson K., Ikeno, Yuji, Hubbard, Gene B., Lenburg, Marc, O'Hara, Steven P., LaRusso, Nicholas F., Miller, Jordan D., Roos, Carolyn M., Verzosa, Grace C., LeBrasseur, Nathan K., Wren, Jonathan D., Farr, Joshua N., Khosla, Sundeep, Stout, Michael B., McGowan, Sara J., Fuhrmann‐Stroissnigg, Heike, Gurkar, Aditi U., Zhao, Jing, Colangelo, Debora, Dorronsoro, Akaitz, Ling, Yuan Yuan, Barghouthy, Amira S., Navarro, Diana C., Sano, Tokio, Robbins, Paul D., Niedernhofer, Laura J., Kirkland, James L.

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Effects of Maternal Global Nutrient Restriction on Fetal Baboon Hepatic Insulin-Like Growth Factor System Genes and Gene Products von Li, Cun, Schlabritz-Loutsevitch, Natalia E, Hubbard, Gene B, Han, Victor, Nygard, Karen, Cox, Laura A, McDonald, Thomas J, Nathanielsz, Peter W

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A Live Attenuated Vaccine for Lassa Fever Made by Reassortment of Lassa and Mopeia Viruses von LUKASHEVICH, Igor S, PATTERSON, Jean, SALVATO, Maria S, CARRION, Ricardo, MOSHKOFF, Dmitry, TICER, Anysha, ZAPATA, Juan, BRASKY, Kathleen, GEIGER, Robert, HUBBARD, Gene B, BRYANT, Joseph

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Spontaneous pathology of the common marmoset (Callithrix jacchus) and tamarins (Saguinus oedipus, Saguinus mystax) von David, John M., Dick Jr, Edward J., Hubbard, Gene B.

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Detection of Anthrax Toxin in the Serum of Animals Infected with Bacillus anthracis by Using Engineered Immunoassays von Mabry, Robert, Brasky, Kathleen, Geiger, Robert, Carrion, Jr, Ricardo, Hubbard, Gene B, Leppla, Stephen, Patterson, Jean L, Georgiou, George, Iverson, B L

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A ML29 reassortant virus protects guinea pigs against a distantly related Nigerian strain of Lassa virus and can provide sterilizing immunity von Carrion, Ricardo, Patterson, Jean L, Johnson, Curtis, Gonzales, Monica, Moreira, Carmen R, Ticer, Anysha, Brasky, Kathleen, Hubbard, Gene B, Moshkoff, Dmitry, Zapata, Juan, Salvato, Maria S, Lukashevich, Igor S

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Phenotypic Features of Circulating Leukocytes from Non-human Primates Naturally Infected with Trypanosoma cruzi Resemble the Major Immunological Findings Observed in Human Chagas D... von Sathler-Avelar, Renato, Vitelli-Avelar, Danielle Marquete, Mattoso-Barbosa, Armanda Moreira, Perdigão-de-Oliveira, Marcelo, Costa, Ronaldo Peres, Elói-Santos, Silvana Maria, Gomes, Matheus de Souza, Amaral, Laurence Rodrigues do, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Dick, Jr, Edward J, Hubbard, Gene B, VandeBerg, Jane F, VandeBerg, John L

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Mortality in captive baboons (Papio spp.): a-23-year study von Dick Jr, Edward J., Owston, Michael A., David, John M., Sharp, R. Mark, Rouse, Scott, Hubbard, Gene B.

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