Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1 von Lazarus, Michael B., Shokat, Kevan M.

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Structure-Based Evolution of Low Nanomolar O‑GlcNAc Transferase Inhibitors von Martin, Sara E. S, Tan, Zhi-Wei, Itkonen, Harri M, Duveau, Damien Y, Paulo, Joao A, Janetzko, John, Boutz, Paul L, Törk, Lisa, Moss, Frederick A, Thomas, Craig J, Gygi, Steven P, Lazarus, Michael B, Walker, Suzanne

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HCF-1 is cleaved in the active site of O-GlcNAc transferase von Lazarus, Michael B, Jiang, Jiaoyang, Kapuria, Vaibhav, Bhuiyan, Tanja, Janetzko, John, Zandberg, Wesley F, Vocadlo, David J, Herr, Winship, Walker, Suzanne

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Structural insights into RNA cleavage by a novel family of bacterial RNases von Wu, Ruoxi, Ingle, Shakti, Barnes, Sarah A, Dahlin, Heather R, Khamrui, Susmita, Xiang, Yufei, Shi, Yi, Bechhofer, David H, Lazarus, Michael B

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Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport von Sherman, David J., Lazarus, Michael B., Murphy, Lea, Liu, Charles, Walker, Suzanne, Ruiz, Natividad, Kahne, Daniel

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Structure-Activity Relationships and Biological Evaluation of 7-Substituted Harmine Analogs for Human β-Cell Proliferation von Kumar, Kunal, Wang, Peng, A Swartz, Ethan, Khamrui, Susmita, Secor, Cody, B Lazarus, Michael, Sanchez, Roberto, F Stewart, Andrew, DeVita, Robert J

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Imaging Peptidoglycan Biosynthesis in Bacillus subtilis with Fluorescent Antibiotics von Tiyanont, Kittichoat, Doan, Thierry, Lazarus, Michael B., Fang, Xiao, Rudner, David Z., Walker, Suzanne

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Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1 von Leandro, João, Khamrui, Susmita, Suebsuwong, Chalada, Chen, Peng-Jen, Secor, Cody, Dodatko, Tetyana, Yu, Chunli, Sanchez, Roberto, DeVita, Robert J, Houten, Sander M, Lazarus, Michael B

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Structure of human O-GlcNAc transferase and its complex with a peptide substrate von Lazarus, Michael B., Nam, Yunsun, Jiang, Jiaoyang, Sliz, Piotr, Walker, Suzanne

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Paclitaxel Induces Calcium Oscillations via an Inositol 1,4,5-Trisphosphate Receptor and Neuronal Calcium Sensor 1-Dependent Mechanism von Boehmerle, Wolfgang, Splittgerber, Ute, Lazarus, Michael B., McKenzie, Kathleen M., Johnston, David G., Austin, David J., Ehrlich, Barbara E.

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A case of hyperlysinemia identified by urine newborn screening von Yeganeh, Mehdi, Auray-Blais, Christiane, Maranda, Bruno, Sabovic, Amanda, DeVita, Robert J, Lazarus, Michael B, Houten, Sander M

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Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors von Lazarus, Michael B, Novotny, Chris J, Shokat, Kevan M

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Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase von Baidin, Vadim, Owens, Tristan W, Lazarus, Michael B, Kahne, Daniel

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Discovery and initial characterization of YloC, a novel endoribonuclease in Bacillus subtilis von Ingle, Shakti, Chhabra, Shivani, Chen, Jiandong, Lazarus, Michael B, Luo, Xing, Bechhofer, David H

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A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase von Jiang, Jiaoyang, Lazarus, Michael B, Pasquina, Lincoln, Sliz, Piotr, Walker, Suzanne

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How the glycosyltransferase OGT catalyzes amide bond cleavage von Janetzko, John, Trauger, Sunia A, Lazarus, Michael B, Walker, Suzanne

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The Antibiotic Novobiocin Binds and Activates the ATPase That Powers Lipopolysaccharide Transport von May, Janine M, Owens, Tristan W, Mandler, Michael D, Simpson, Brent W, Lazarus, Michael B, Sherman, David J, Davis, Rebecca M, Okuda, Suguru, Massefski, Walter, Ruiz, Natividad, Kahne, Daniel

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A Small Molecule That Inhibits OGT Activity in Cells von Ortiz-Meoz, Rodrigo F, Jiang, Jiaoyang, Lazarus, Michael B, Orman, Marina, Janetzko, John, Fan, Chenguang, Duveau, Damien Y, Tan, Zhi-Wei, Thomas, Craig J, Walker, Suzanne

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Structural snapshots of the reaction coordinate for O-GlcNAc transferase von Lazarus, Michael B, Jiang, Jiaoyang, Gloster, Tracey M, Zandberg, Wesley F, Whitworth, Garrett E, Vocadlo, David J, Walker, Suzanne

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High-Resolution Structure and Inhibition of the Schizophrenia-Linked Pseudokinase ULK4 von Khamrui, Susmita, Ung, Peter M. U, Secor, Cody, Schlessinger, Avner, Lazarus, Michael B

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