Preclinical Profile of BI 224436, a Novel HIV-1 Non-Catalytic-Site Integrase Inhibitor von FENWICK, Craig, AMAD, Ma'an, FADER, Lee D, FAUCHER, Anne-Marie, GARNEAU, Michel, JAKALIAN, Araz, KAWAI, Stephen, LAMORTE, Louie, LAPLANTE, Steven, LAIBIN LUO, MASON, Steve, POUPART, Marc-André, BAILEY, Murray D, RIOUX, Nathalie, SCHROEDER, Patricia, SIMONEAU, Bruno, TREMBLAY, Sonia, TSANTRIZOS, Youla, WITVROUW, Myriam, YOAKIM, Christiane, BETHELL, Richard, BÖS, Michael, BONNEAU, Pierre, CORDINGLEY, Michael, COULOMBE, René, DUAN, Jianmin, EDWARDS, Paul

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A potassium channel agonist protects hearing function and promotes outer hair cell survival in a mouse model for age-related hearing loss von Peixoto Pinheiro, Barbara, Müller, Marcus, Bös, Michael, Guezguez, Jamil, Burnet, Michael, Tornincasa, Mara, Rizzetto, Riccardo, Rolland, Jean-Francois, Liberati, Chiara, Lohmer, Stefan, Adel, Youssef, Löwenheim, Hubert

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Conformation-Based Restrictions and Scaffold Replacements in the Design of Hepatitis C Virus Polymerase Inhibitors: Discovery of Deleobuvir (BI 207127) von LaPlante, Steven R., Bös, Michael, Brochu, Christian, Chabot, Catherine, Coulombe, René, Gillard, James R., Jakalian, Araz, Poirier, Martin, Rancourt, Jean, Stammers, Timothy, Thavonekham, Bounkham, Beaulieu, Pierre L., Kukolj, George, Tsantrizos, Youla S.

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Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor (BILB 1941) with Demonstrated Antiviral Activity in Patients Chronically Infected with Genotype 1 Hepatitis C Virus... von Beaulieu, Pierre L, Bös, Michael, Cordingley, Michael G, Chabot, Catherine, Fazal, Gulrez, Garneau, Michel, Gillard, James R, Jolicoeur, Eric, LaPlante, Steven, McKercher, Ginette, Poirier, Martin, Poupart, Marc-André, Tsantrizos, Youla S, Duan, Jianmin, Kukolj, George

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Discovery of a Potent and Selective Noncovalent Linear Inhibitor of the Hepatitis C Virus NS3 Protease (BI 201335) von Llinàs-Brunet, Montse, Bailey, Murray D, Goudreau, Nathalie, Bhardwaj, Punit K, Bordeleau, Josée, Bös, Michael, Bousquet, Yves, Cordingley, Michael G, Duan, Jiamin, Forgione, Pat, Garneau, Michel, Ghiro, Elise, Gorys, Vida, Goulet, Sylvie, Halmos, Ted, Kawai, Stephen H, Naud, Julie, Poupart, Marc-André, White, Peter W

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Discovery of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly von Fader, Lee D., Bethell, Richard, Bonneau, Pierre, Bös, Michael, Bousquet, Yves, Cordingley, Michael G., Coulombe, René, Deroy, Patrick, Faucher, Anne-Marie, Gagnon, Alexandre, Goudreau, Nathalie, Grand-Maître, Chantal, Guse, Ingrid, Hucke, Oliver, Kawai, Stephen H., Lacoste, Jean-Eric, Landry, Serge, Lemke, Christopher T., Malenfant, Eric, Mason, Stephen, Morin, Sébastien, O’Meara, Jeff, Simoneau, Bruno, Titolo, Steve, Yoakim, Christiane

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Discovery of BI 207524, an Indole Diamide NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection von Beaulieu, Pierre L, Anderson, Paul C, Bethell, Richard, Bös, Michael, Bousquet, Yves, Brochu, Christian, Cordingley, Michael G, Fazal, Gulrez, Garneau, Michel, Gillard, James R, Kawai, Stephen, Marquis, Martin, McKercher, Ginette, Poupart, Marc-André, Stammers, Timothy, Thavonekham, Bounkham, Wernic, Dominik, Duan, Jianmin, Kukolj, George

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Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor (BILB 1941) with Demonstrated Antiviral Activity in Patients Chronically Infected with Genotype 1 Hepatitis C Virus... von Beaulieu, Pierre L, Bös, Michael, Cordingley, Michael G, Chabot, Catherine, Fazal, Gulrez, Garneau, Michel, Gillard, James R, Jolicoeur, Eric, LaPlante, Steven, McKercher, Ginette, Poirier, Martin, Poupart, Marc-André, Tsantrizos, Youla S, Duan, Jianmin, Kukolj, George

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Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists von Hoffmann, Torsten, Bös, Michael, Stadler, Heinz, Schnider, Patrick, Hunkeler, Walter, Godel, Thierry, Galley, Guido, Ballard, Theresa M., Higgins, Guy A., Poli, Sonia M., Sleight, Andrew J.

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Effect of Anesthesia on Microelectrode Recordings during Deep Brain Stimulation Surgery in Tourette Syndrome Patients von Bos, Michael J., Alzate Sanchez, Ana Maria, Smeets, Anouk Y.J.M., Bancone, Raffaella, Ackermans, Linda, Absalom, Anthony R., Buhre, Wolfgang F., Roberts, Mark J., Janssen, Marcus L.F.

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Involvement of 5‐HT6 receptors in nigro‐striatal function in rodents von Bourson, Anne, Boess, Frank G, Bös, Michael, Sleight, Andrew J

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Can disparity in access to living‐donor kidney transplants between ethnic groups be mitigated? von Bos, Michael

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Pediatric Deceased Donation—A Report of the Transplantation Society Meeting in Geneva von Martin, Dominique E, Nakagawa, Thomas A, Siebelink, Marion J, Bramstedt, Katrina A, Brierley, Joe, Dobbels, Fabienne, Rodrigue, James R, Sarwal, Minnie, Shapiro, Ron, Dominguez-Gil, Beatriz, Danovitch, Gabriel, Sweet, Stuart C, Trompeter, Richard S, Moazam, Farhat, Bos, Michael A, Delmonico, Francis L

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Asymmetric Jugular Veins: Implication for Central Venous Access in the ICU von Bos, Michaël J., van Mook, Walther N. K. A., van Zundert, André A. J.

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Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV‑1 von Fader, Lee D, Malenfant, Eric, Parisien, Mathieu, Carson, Rebekah, Bilodeau, François, Landry, Serge, Pesant, Marc, Brochu, Christian, Morin, Sébastien, Chabot, Catherine, Halmos, Ted, Bousquet, Yves, Bailey, Murray D, Kawai, Stephen H, Coulombe, René, LaPlante, Steven, Jakalian, Araz, Bhardwaj, Punit K, Wernic, Dominik, Schroeder, Patricia, Amad, Ma’an, Edwards, Paul, Garneau, Michel, Duan, Jianmin, Cordingley, Michael, Bethell, Richard, Mason, Stephen W, Bös, Michael, Bonneau, Pierre, Poupart, Marc-André, Faucher, Anne-Marie, Simoneau, Bruno, Fenwick, Craig, Yoakim, Christiane, Tsantrizos, Youla

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Ethical and legal issues in non-heart-beating organ donation von BOS, Michael A

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Impact of Procedural Sedation on the Clinical Outcome of Microelectrode Recording Guided Deep Brain Stimulation in Patients with Parkinson's Disease von Bos, Michael J., de Korte-de Boer, Dianne, Alzate Sanchez, Ana Maria, Duits, Annelien, Ackermans, Linda, Temel, Yasin, Absalom, Anthony R., Buhre, Wolfgang F., Roberts, Mark J., Janssen, Marcus L. F.

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Influence of Anesthesia and Clinical Variables on the Firing Rate, Coefficient of Variation and Multi-Unit Activity of the Subthalamic Nucleus in Patients with Parkinson's Disease von Bos, Michael J., Sanchez, Ana Maria Alzate, Bancone, Raffaella, Temel, Yasin, de Greef, Bianca Ta, Absalom, Anthony R., Gommer, Erik D., van Kranen-Mastenbroek, Vivianne H. J. M., Buhre, Wolfgang F., Roberts, Mark J., Janssen, Marcus L. F.

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Novel compounds useful as potassium channel openers von BÖS, Michael

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Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors von Stammers, Timothy A., Coulombe, René, Rancourt, Jean, Thavonekham, Bounkham, Fazal, Gulrez, Goulet, Sylvie, Jakalian, Araz, Wernic, Dominic, Tsantrizos, Youla, Poupart, Marc-André, Bös, Michael, McKercher, Ginette, Thauvette, Louise, Kukolj, George, Beaulieu, Pierre L.

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