Intermediates Released from a Polyether-Producing Polyketide Synthase Provide Insight into the Mechanism of Oxidative Cyclization von Hughes-Thomas, Zoë A., Stark, Christian B. W., Böhm, Ines U., Staunton, James, Leadlay, Peter F.

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Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase von Rowe, Christine J, Böhm, Ines U, Thomas, Iain P, Wilkinson, Barrie, Rudd, Brian A.M, Foster, Graham, Blackaby, Andrew P, Sidebottom, Philip J, Roddis, Ylva, Buss, Anthony D, Staunton, James, Leadlay, Peter F

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Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase von Wilkinson, B, Foster, G, Rudd, B A, Taylor, N L, Blackaby, A P, Sidebottom, P J, Cooper, D J, Dawson, M J, Buss, A D, Gaisser, S, Böhm, I U, Rowe, C J, Cortés, J, Leadlay, P F, Staunton, J

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Intermediates Released from a Polyether-Producing Polyketide Synthase Provide Insight into the Mechanism of Oxidative Cyclization von Hughes-Thomas, Zoë A., Stark, Christian B. W., Böhm, Ines U., Staunton, James, Leadlay, Peter F.

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Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer von Peifer, Martin, Fernández-Cuesta, Lynnette, Sos, Martin L, George, Julie, Seidel, Danila, Kasper, Lawryn H, Plenker, Dennis, Leenders, Frauke, Sun, Ruping, Zander, Thomas, Menon, Roopika, Koker, Mirjam, Dahmen, Ilona, Müller, Christian, Di Cerbo, Vincenzo, Schildhaus, Hans-Ulrich, Altmüller, Janine, Baessmann, Ingelore, Becker, Christian, de Wilde, Bram, Vandesompele, Jo, Böhm, Diana, Ansén, Sascha, Gabler, Franziska, Wilkening, Ines, Heynck, Stefanie, Heuckmann, Johannes M, Lu, Xin, Carter, Scott L, Cibulskis, Kristian, Banerji, Shantanu, Getz, Gad, Park, Kwon-Sik, Rauh, Daniel, Grütter, Christian, Fischer, Matthias, Pasqualucci, Laura, Wright, Gavin, Wainer, Zoe, Russell, Prudence, Petersen, Iver, Chen, Yuan, Stoelben, Erich, Ludwig, Corinna, Schnabel, Philipp, Hoffmann, Hans, Muley, Thomas, Brockmann, Michael, Engel-Riedel, Walburga, Muscarella, Lucia A, Fazio, Vito M, Groen, Harry, Timens, Wim, Sietsma, Hannie, Thunnissen, Erik, Smit, Egbert, Heideman, Daniëlle A M, Snijders, Peter J F, Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Field, John, Solberg, Steinar, Brustugun, Odd Terje, Lund-Iversen, Marius, Sänger, Jörg, Clement, Joachim H, Soltermann, Alex, Moch, Holger, Weder, Walter, Solomon, Benjamin, Soria, Jean-Charles, Validire, Pierre, Besse, Benjamin, Brambilla, Elisabeth, Brambilla, Christian, Lantuejoul, Sylvie, Lorimier, Philippe, Schneider, Peter M, Hallek, Michael, Pao, William, Meyerson, Matthew, Sage, Julien, Shendure, Jay, Schneider, Robert, Büttner, Reinhard, Wolf, Jürgen, Nürnberg, Peter, Perner, Sven, Heukamp, Lukas C, Brindle, Paul K, Haas, Stefan, Thomas, Roman K

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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis von Voight, Benjamin F, Scott, Laura J, Morris, Andrew P, Dina, Christian, Welch, Ryan P, Zeggini, Eleftheria, Huth, Cornelia, Aulchenko, Yurii S, McCulloch, Laura J, Ferreira, Teresa, Grallert, Harald, Wu, Guanming, Raychaudhuri, Soumya, Langenberg, Claudia, Dupuis, Josée, Qi, Lu, Segrè, Ayellet V, van Hoek, Mandy, Navarro, Pau, Benediktsson, Rafn, Bonnycastle, Lori L, Charpentier, Guillaume, Cornelis, Marilyn, Couper, David J, Crawford, Gabe, Doney, Alex S F, Elliott, Amanda L, Erdos, Michael R, Grarup, Niels, Green, Todd, Groves, Christopher J, Guiducci, Candace, Hadjadj, Samy, Hassanali, Neelam, Isomaa, Bo, Johnson, Paul R V, Jørgensen, Torben, Kao, Wen H L, Klopp, Norman, Kong, Augustine, Kraft, Peter, Lauritzen, Torsten, Li, Man, Marre, Michel, Midthjell, Kristian, Morken, Mario A, Narisu, Narisu, Owen, Katharine R, Payne, Felicity, Perry, John R B, Petersen, Ann-Kristin, Platou, Carl, Proença, Christine, Prokopenko, Inga, Rathmann, Wolfgang, Rayner, N William, Rocheleau, Ghislain, Sampson, Michael J, Saxena, Richa, Shields, Beverley M, Shrader, Peter, Sigurdsson, Gunnar, Sparsø, Thomas, Stringham, Heather M, Sun, Qi, Swift, Amy J, Thorand, Barbara, Tichet, Jean, van Haeften, Timon W, van Herpt, Thijs, Walters, G Bragi, Weedon, Michael N, Wijmenga, Cisca, Witteman, Jacqueline, Bergman, Richard N, Cauchi, Stephane, Collins, Francis S, Gyllensten, Ulf, Hofman, Albert, Hunter, David J, Hveem, Kristian, Pramstaller, Peter P, Uitterlinden, Andre, Walker, Mark, Wareham, Nicholas J, Abecasis, Gonçalo R, Boehm, Bernhard O, Campbell, Harry, Daly, Mark J, Hu, Frank B, Meigs, James B, Pankow, James S, Pedersen, Oluf, Wichmann, H-Erich, Barroso, Inês, Florez, Jose C, Thorsteinsdottir, Unnur, Froguel, Philippe, van Duijn, Cornelia M, Stefansson, Kari

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Engineering of a minimal modular polyketide synthase, and targeted alteration of the stereospecificity of polyketide chain extension von Böhm, Ines, Holzbaur, Inès E., Hanefeld, Ulf, Cortési, Jesus, Staunton, Jim, Leadlay, Peter F.

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