Limited clinical relevance of imaging techniques in the follow-up of patients with advanced chronic lymphocytic leukemia: results of a meta-analysis von Eichhorst, Barbara F., Fischer, Kirsten, Fink, Anna-Maria, Elter, Thomas, Wendtner, Clemens M., Goede, Valentin, Bergmann, Manuela, Stilgenbauer, Stephan, Hopfinger, Georg, Ritgen, Matthias, Bahlo, Jasmin, Busch, Raymonde, Hallek, Michael

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Roles of the Ras Raf MEK ERK pathway in leukemia therapy von Steelman, L S, Franklin, R A, Abrams, S L, Chappell, W, Kempf, C R, Bäsecke, J, Stivala, F, Donia, M, Fagone, P, Nicoletti, F, Libra, M, Ruvolo, P, Ruvolo, V, Evangelisti, C, Martelli, A M, McCubrey, J A

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Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K PTEN Akt mTOR pathway von Martelli, A M, Evangelisti, C, Chappell, W, Abrams, S L, Bäsecke, J, Stivala, F, Donia, M, Fagone, P, Nicoletti, F, Libra, M, Ruvolo, V, Ruvolo, P, Kempf, C R, Steelman, L S, McCubrey, J A

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Contributions of the Raf MEK ERK, PI3K PTEN Akt mTOR and Jak STAT pathways to leukemia von Steelman, L S, Abrams, S L, Whelan, J, Bertrand, F E, Ludwig, D E, Bäsecke, J, Libra, M, Stivala, F, Milella, M, Tafuri, A, Lunghi, P, Bonati, A, Martelli, A M, McCubrey, J A

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Targeting survival cascades induced by activation of Ras Raf MEK ERK, PI3K PTEN Akt mTOR and Jak STAT pathways for effective leukemia therapy von McCubrey, J A, Steelman, L S, Abrams, S L, Bertrand, F E, Ludwig, D E, Bäsecke, J, Libra, M, Stivala, F, Milella, M, Tafuri, A, Lunghi, P, Bonati, A, Martelli, A M

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Targeting the leukemic stem cell: the Holy Grail of leukemia therapy von Misaghian, N, Ligresti, G, Steelman, L S, Bertrand, F E, Bäsecke, J, Libra, M, Nicoletti, F, Stivala, F, Milella, M, Tafuri, A, Cervello, M, Martelli, A M, McCubrey, J A

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Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging von Steelman, Linda S, Chappell, William H, Abrams, Stephen L, Kempf, Ruth C, Long, Jacquelyn, Laidler, Piotr, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Stivala, Franca, Mazzarino, Maria C, Donia, Marco, Fagone, Paolo, Malaponte, Graziella, Nicoletti, Ferdinando, Libra, Massimo, Milella, Michele, Tafuri, Agostino, Bonati, Antonio, Bäsecke, Jörg, Cocco, Lucio, Evangelisti, Camilla, Martelli, Alberto M, Montalto, Giuseppe, Cervello, Melchiorre, McCubrey, James A

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Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance von McCubrey, James A, Steelman, Linda S, Chappell, William H, Abrams, Stephen L, Franklin, Richard A, Montalto, Giuseppe, Cervello, Melchiorre, Libra, Massimo, Candido, Saverio, Malaponte, Grazia, Mazzarino, Maria C, Fagone, Paolo, Nicoletti, Ferdinando, Bäsecke, Jörg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Milella, Michele, Tafuri, Agostino, Chiarini, Francesca, Evangelisti, Camilla, Cocco, Lucio, Martelli, Alberto M

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Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response von McCubrey, James A, Steelman, Linda S, Chappell, William H, Abrams, Stephen L, Montalto, Giuseppe, Cervello, Melchiorre, Nicoletti, Ferdinando, Fagone, Paolo, Malaponte, Grazia, Mazzarino, Maria C, Candido, Saverio, Libra, Massimo, Bäsecke, Jörg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Milella, Michele, Tafuri, Agostino, Cocco, Lucio, Evangelisti, Camilla, Chiarini, Francesca, Martelli, Alberto M

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Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways von McCubrey, James A., Steelman, Linda S., Kempf, C. Ruth, Chappell, William H., Abrams, Stephen L., Stivala, Franca, Malaponte, Graziella, Nicoletti, Ferdinando, Libra, Massimo, Bäsecke, Jörg, Maksimovic-Ivanic, Danijela, Mijatovic, Sanja, Montalto, Giuseppe, Cervello, Melchiorre, Cocco, Lucio, Martelli, Alberto M.

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The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy von Abrams, Stephen L., Steelman, Linda S., Shelton, John G., Wong, Ellis W.T., Chappell, William H., Bäsecke, Jörg, Stivala, Franca, Donia, Marco, Nicoletti, Ferdinando, Libra, Massimo, Martelli, Alberto M., McCubrey, James A

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Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health von Chappell, William H, Steelman, Linda S, Long, Jacquelyn M, Kempf, Ruth C, Abrams, Stephen L, Franklin, Richard A, Bäsecke, Jörg, Stivala, Franca, Donia, Marco, Fagone, Paolo, Malaponte, Graziella, Mazzarino, Maria C, Nicoletti, Ferdinando, Libra, Massimo, Maksimovic-Ivanic, Danijela, Mijatovic, Sanja, Montalto, Giuseppe, Cervello, Melchiorre, Laidler, Piotr, Milella, Michele, Tafuri, Agostino, Bonati, Antonio, Evangelisti, Camilla, Cocco, Lucio, Martelli, Alberto M, McCubrey, James A

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Early versus Delayed Tumor-Specific Therapy and Survival in Patients with Lung Cancer: A Retrospective Study von Geiken-Weinstock, Rike, Reyners, Anna K.L., Griesinger, Frank, Otremba, Burkhard Joerg, Hoheisel, Michael, Bäsecke, Jörg

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Involvement of p53 and Raf MEK ERK pathways in hematopoietic drug resistance von McCubrey, J A, Abrams, S L, Ligresti, G, Misaghian, N, Wong, E W T, Steelman, L S, Bäsecke, J, Troppmair, J, Libra, M, Nicoletti, F, Molton, S, McMahon, M, Evangelisti, C, Martelli, A M

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Advances in targeting signal transduction pathways von McCubrey, James A, Steelman, Linda S, Chappell, William H, Sun, Lin, Davis, Nicole M, Abrams, Stephen L, Franklin, Richard A, Cocco, Lucio, Evangelisti, Camilla, Chiarini, Francesca, Martelli, Alberto M, Libra, Massimo, Candido, Saverio, Ligresti, Giovanni, Malaponte, Grazia, Mazzarino, Maria C, Fagone, Paolo, Donia, Marco, Nicoletti, Ferdinando, Polesel, Jerry, Talamini, Renato, Bäsecke, Jörg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Michele, Michele, Tafuri, Agostino, Dulińska-Litewka, Joanna, Laidler, Piotr, D'Assoro, Antonio B, Drobot, Lyudmyla, Umezawa, Drobot, Montalto, Giuseppe, Cervello, Melchiorre, Demidenko, Zoya N

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Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs von Steelman, Linda S., Abrams, Stephen L., Shelton, John G., Chappell, William H., Bäsecke, Jörg, Stivala, Franca, Donia, Marco, Nicoletti, Ferdinando, Libra, Massimo, Martelli, Alberto M., McCubrey, James A

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Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells von Horn, S, Bergholz, U, Jücker, M, McCubrey, J A, Trümper, L, Stocking, C, Bäsecke, J

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Molecular Profile and Cytomorphological Manifestation of Isolated Y Loss in Myelodysplastic Syndromes von Ganster, Christina, Harder, Lana, Bacher, Ulrike, Shirneshan, Katayoon, Dierks, Sascha, Martin, Roman, Rittscher, Katharina, Strupp, Corinna, Salinas, Gabriela, Bäsecke, Jörg, Glass, Bertram, Elmaagacli, Ahmet, Braulke, Friederike, Siehl, Siegfried, Sievers, Bernd, Söling, Urlike, Schanz, Julie, Stolze, Martin, Heudobler, Daniel, Germing, Ulrich, Haase, Detlef

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Primary osteomyelofibrosis and an XX‐male genotype von Schanz, Julie, Haase, Detlef, Steuernagel, Peter, Shirneshan, Katayoo, Bäsecke, Jörg

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Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy von Abrams, Stephen L., Steelman, Linda S., Shelton, John G., Chappell, William, Bäsecke, Jörg, Stivala, Franca, Donia, Marco, Nicoletti, Ferdinando, Libra, Massimo, Martelli, Alberto M., McCubrey, James A

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