DNA damage signalling guards against activated oncogenes and tumour progression von Bartek, J, Bartkova, J, Lukas, J

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SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair von Kanu, N, Grönroos, E, Martinez, P, Burrell, R A, Yi Goh, X, Bartkova, J, Maya-Mendoza, A, Mistrík, M, Rowan, A J, Patel, H, Rabinowitz, A, East, P, Wilson, G, Santos, C R, McGranahan, N, Gulati, S, Gerlinger, M, Birkbak, N J, Joshi, T, Alexandrov, L B, Stratton, M R, Powles, T, Matthews, N, Bates, P A, Stewart, A, Szallasi, Z, Larkin, J, Bartek, J, Swanton, C

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Markers associated with genomic instability, immunogenicity and immune therapy responsiveness in Metaplastic carcinoma of the breast: Expression of γH2AX, pRPA2, P53, PD-L1 and tum... von Voutilainen, S, Heikkilä, P, Bartkova, J, Nevanlinna, H, Blomqvist, C, Bartek, J, Mattson, J

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Replication stress and oxidative damage contribute to aberrant constitutive activation of DNA damage signalling in human gliomas von Bartkova, J, Hamerlik, P, Stockhausen, M-T, Ehrmann, J, Hlobilkova, A, Laursen, H, Kalita, O, Kolar, Z, Poulsen, H S, Broholm, H, Lukas, J, Bartek, J

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Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress von Chroma, K, Mistrik, M, Moudry, P, Gursky, J, Liptay, M, Strauss, R, Skrott, Z, Vrtel, R, Bartkova, J, Kramara, J, Bartek, J

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The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis von Evangelou, K, Bartkova, J, Kotsinas, A, Pateras, I S, Liontos, M, Velimezi, G, Kosar, M, Liloglou, T, Trougakos, I P, Dyrskjot, L, Andersen, C L, Papaioannou, M, Drosos, Y, Papafotiou, G, Hodny, Z, Sosa-Pineda, B, Wu, X-R, Klinakis, A, Ørntoft, T, Lukas, J, Bartek, J, Gorgoulis, V G

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A high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage response von Schepeler, T, Lamy, P, Hvidberg, V, Laurberg, J R, Fristrup, N, Reinert, T, Bartkova, J, Tropia, L, Bartek, J, Halazonetis, T D, Pan, C-C, Borre, M, Dyrskjøt, L, Ørntoft, T F

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DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy von Bennetzen, Martin V., Kosar, Martin, Bunkenborg, Jakob, Payne, Mark Ronald, Bartkova, Jirina, Lindström, Mikael S., Lukas, Jiri, Andersen, Jens S., Bartek, Jiri, Larsen, Dorthe Helena

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Overabundant FANCD2, alone and combined with NQO1, is a sensitive marker of adverse prognosis in breast cancer von Fagerholm, R., Sprott, K., Heikkinen, T., Bartkova, J., Heikkilä, P., Aittomäki, K., Bartek, J., Weaver, D., Blomqvist, C., Nevanlinna, H.

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The influence of temperature, relative humidity and rainfall on the occurrence of pollen allergens (Betula, Poaceae, Ambrosia artemisiifolia) in the atmosphere of Bratislava (Slova... von Bartková-Scevková, J

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DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours von Bartkova, J, Hořejs̆í, Z, Sehested, M, Nesland, J M, Rajpert-De Meyts, E, Skakkebæk, N E, Stucki, M, Jackson, S, Lukas, J, Bartek, J

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Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint von Lukas, Jiri, Bartkova, Jirina, Bartek, Jiri

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The DNA damage signalling kinase ATM is aberrantly reduced or lost in BRCA1 BRCA2-deficient and ER PR ERBB2-triple-negative breast cancer von Tommiska, J, Bartkova, J, Heinonen, M, Hautala, L, Kilpivaara, O, Eerola, H, Aittomäki, K, Hofstetter, B, Lukas, J, von Smitten, K, Blomqvist, C, Ristimäki, A, Heikkilä, P, Bartek, J, Nevanlinna, H

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Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state von Maya-Mendoza, A, Merchut-Maya, J M, Bartkova, J, Bartek, J, Streuli, C H, Jackson, D A

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Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4 von Skrott, Zdenek, Mistrik, Martin, Andersen, Klaus Kaae, Friis, Søren, Majera, Dusana, Gursky, Jan, Ozdian, Tomas, Bartkova, Jirina, Turi, Zsofia, Moudry, Pavel, Kraus, Marianne, Michalova, Martina, Vaclavkova, Jana, Dzubak, Petr, Vrobel, Ivo, Pouckova, Pavla, Sedlacek, Jindrich, Miklovicova, Andrea, Kutt, Anne, Li, Jing, Mattova, Jana, Driessen, Christoph, Dou, Q. Ping, Olsen, Jørgen, Hajduch, Marian, Cvek, Boris, Deshaies, Raymond J., Bartek, Jiri

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Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth von Hamerlik, Petra, Lathia, Justin D, Rasmussen, Rikke, Wu, Qiulian, Bartkova, Jirina, Lee, MyungHee, Moudry, Pavel, Bartek, Jr, Jiri, Fischer, Walter, Lukas, Jiri, Rich, Jeremy N, Bartek, Jiri

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Autophagy role(s) in response to oncogenes and DNA replication stress von Vanzo, Riccardo, Bartkova, Jirina, Merchut-Maya, Joanna Maria, Hall, Arnaldur, Bouchal, Jan, Dyrskjøt, Lars, Frankel, Lisa B., Gorgoulis, Vassilis, Maya-Mendoza, Apolinar, Jäättelä, Marja, Bartek, Jiri

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Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity von Lukas, Jiri, Bartkova, Jirina, Rohde, Mikkel, Strauss, Michael, Bartek, Jiri

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AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity von Maiani, Emiliano, Milletti, Giacomo, Nazio, Francesca, Holdgaard, Søs Grønbæk, Bartkova, Jirina, Rizza, Salvatore, Cianfanelli, Valentina, Lorente, Mar, Simoneschi, Daniele, Di Marco, Miriam, D’Acunzo, Pasquale, Di Leo, Luca, Rasmussen, Rikke, Montagna, Costanza, Raciti, Marilena, De Stefanis, Cristiano, Gabicagogeascoa, Estibaliz, Rona, Gergely, Salvador, Nélida, Pupo, Emanuela, Merchut-Maya, Joanna Maria, Daniel, Colin J., Carinci, Marianna, Cesarini, Valeriana, O’sullivan, Alfie, Jeong, Yeon-Tae, Bordi, Matteo, Russo, Francesco, Campello, Silvia, Gallo, Angela, Filomeni, Giuseppe, Lanzetti, Letizia, Sears, Rosalie C., Hamerlik, Petra, Bartolazzi, Armando, Hynds, Robert E., Pearce, David R., Swanton, Charles, Pagano, Michele, Velasco, Guillermo, Papaleo, Elena, De Zio, Daniela, Maya-Mendoza, Apolinar, Locatelli, Franco, Bartek, Jiri, Cecconi, Francesco

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Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps von Paes Dias, Mariana, Tripathi, Vivek, van der Heijden, Ingrid, Cong, Ke, Manolika, Eleni-Maria, Bhin, Jinhyuk, Gogola, Ewa, Galanos, Panagiotis, Annunziato, Stefano, Lieftink, Cor, Andújar-Sánchez, Miguel, Chakrabarty, Sanjiban, Smith, Graeme C.M., van de Ven, Marieke, Beijersbergen, Roderick L., Bartkova, Jirina, Rottenberg, Sven, Cantor, Sharon, Bartek, Jiri, Ray Chaudhuri, Arnab, Jonkers, Jos

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