Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis von Subedi, Amit, Liu, Qiang, Ayyathan, Dhanoop M., Sharon, David, Cathelin, Severine, Hosseini, Mohsen, Xu, Changjiang, Voisin, Veronique, Bader, Gary D., D’Alessandro, Angelo, Lechman, Eric R., Dick, John E., Minden, Mark D., Wang, Jean C.Y., Chan, Steven M.

Volltext

Inhibition of PINK1-Dependent Mitochondrial Quality Control Pathways Induces Senescence of Acute Myeloid Leukemia Stem Cells von Manikoth Ayyathan, Dhanoop, Sharon, David, Cathelin, Severine, Chan, Steven M

Volltext

Metformin Treatment Abrogates the Competitive Advantage of Dnmt3a R878H HSPCs By Enhancing DNA Methylation Activity von Hosseini, Mohsen, Cathelin, Severine, Liu, Alex, Yang, Yitong, Subedi, Amit, Manikoth Ayyathan, Dhanoop, Pai, Shraddha, Chan, Steven M.

Volltext

Targeting STAT5 Signaling Overcomes Resistance to IDH Inhibitors in Acute Myeloid Leukemia through Suppression of Stemness von Liu, Alex C H, Cathelin, Severine, Yang, Yitong, Dai, David L, Ayyathan, Dhanoop Manikoth, Hosseini, Mohsen, Minden, Mark D, Tierens, Anne, Chan, Steven M

Volltext