Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients von Menzel, Michael, Ossowski, Stephan, Kral, Sebastian, Metzger, Patrick, Horak, Peter, Marienfeld, Ralf, Boerries, Melanie, Wolter, Steffen, Ball, Markus, Neumann, Olaf, Armeanu-Ebinger, Sorin, Schroeder, Christopher, Matysiak, Uta, Goldschmid, Hannah, Schipperges, Vincent, Fürstberger, Axel, Allgäuer, Michael, Eberhardt, Timo, Niewöhner, Jakob, Blaumeiser, Andreas, Ploeger, Carolin, Haack, Tobias Bernd, Tay, Timothy Kwang Yong, Kelemen, Olga, Pauli, Thomas, Kirchner, Martina, Kluck, Klaus, Ott, Alexander, Renner, Marcus, Admard, Jakob, Gschwind, Axel, Lassmann, Silke, Kestler, Hans, Fend, Falko, Illert, Anna Lena, Werner, Martin, Möller, Peter, Seufferlein, Thomas Theodor Werner, Malek, Nisar, Schirmacher, Peter, Fröhling, Stefan, Kazdal, Daniel, Budczies, Jan, Stenzinger, Albrecht

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Biallelic MAD2L1BP (p31comet) mutation is associated with mosaic aneuploidy and juvenile granulosa cell tumors von Abdel-Salam, Ghada M H, Hellmuth, Susanne, Gradhand, Elise, Käseberg, Stephan, Winter, Jennifer, Pabst, Ann-Sophie, Eid, Maha M, Thiele, Holger, Nürnberg, Peter, Budde, Birgit S, Toliat, Mohammad Reza, Brecht, Ines B, Schroeder, Christopher, Gschwind, Axel, Ossowski, Stephan, Häuser, Friederike, Rossmann, Heidi, Abdel-Hamid, Mohamed S, Hegazy, Ibrahim, Mohamed, Ahmed G, Schneider, Dominik T, Bertoli-Avella, Aida, Bauer, Peter, Pearring, Jillian N, Pfundt, Rolph, Hoischen, Alexander, Gilissen, Christian, Strand, Dennis, Zechner, Ulrich, Tashkandi, Soha A, Faqeih, Eissa A, Stemmann, Olaf, Strand, Susanne, Bolz, Hanno J

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Detection of circulating cell-free HPV DNA of 13 HPV types for patients with cervical cancer as potential biomarker to monitor therapy response and to detect relapse von Mittelstadt, Suzana, Kelemen, Olga, Admard, Jakob, Gschwind, Axel, Koch, André, Wörz, Sarah, Oberlechner, Ernst, Engler, Tobias, Bonzheim, Irina, Staebler, Annette, Weidner, Nicola, Stubenrauch, Frank, Iftner, Thomas, Riess, Olaf, Schroeder, Christopher, Kommoss, Stefan, Ossowski, Stephan

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MDM2, MDM4 and EGFR Amplifications and Hyperprogression in Metastatic Acral and Mucosal Melanoma von Forschner, Andrea, Hilke, Franz-Joachim, Bonzheim, Irina, Gschwind, Axel, Demidov, German, Amaral, Teresa, Ossowski, Stephan, Riess, Olaf, Schroeder, Christopher, Martus, Peter, Klumpp, Bernhard, Gonzalez-Menendez, Irene, Garbe, Claus, Niessner, Heike, Sinnberg, Tobias

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TMB and BRAF mutation status are independent predictive factors in high-risk melanoma patients with adjuvant anti-PD-1 therapy von Eckardt, Julia, Schroeder, Christopher, Martus, Peter, Armeanu-Ebinger, Sorin, Kelemen, Olga, Gschwind, Axel, Bonzheim, Irina, Eigentler, Thomas, Amaral, Teresa, Ossowski, Stephan, Rieß, Olaf, Flatz, Lukas, Garbe, Claus, Forschner, Andrea

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Distinct Mutation Patterns Reveal Melanoma Subtypes and Influence Immunotherapy Response in Advanced Melanoma Patients von Hilke, Franz J., Sinnberg, Tobias, Gschwind, Axel, Niessner, Heike, Demidov, German, Amaral, Teresa, Ossowski, Stephan, Bonzheim, Irina, Roecken, Martin, Riess, Olaf, Garbe, Claus, Schroeder, Christopher, Forschner, Andrea

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Germline findings in patients with advanced malignancies screened with paired blood–tumour testing for personalised treatment approaches von Roggia, Cristiana, Armeanu-Ebinger, Sorin, Gschwind, Axel, Seibel-Kelemen, Olga, Hertler, Sonja, Faust, Ulrike, Liebmann, Alexandra, Haack, Tobias B., Neumann, Manuela, Bonzheim, Irina, Forschner, Andrea, Kopp, Hans-Georg, Herster, Franziska, Hartkopf, Andreas, Bitzer, Michael, Malek, Nisar P., Brecht, Ines B., Ruhm, Kristina, Möller, Yvonne, Löwenheim, Hubert, Ossowski, Stephan, Rieß, Olaf H., Schroeder, Christopher

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UV-radiation and MC1R germline mutations are risk factors for the development of conventional and spitzoid melanomas in children and adolescentsResearch in context von Alexandra Liebmann, Jakob Admard, Sorin Armeanu-Ebinger, Hannah Wild, Michael Abele, Axel Gschwind, Olga Seibel-Kelemen, Christian Seitz, Irina Bonzheim, Olaf Riess, German Demidov, Marc Sturm, Malou Schadeck, Michaela Pogoda, Ewa Bien, Malgorzata Krawczyk, Eva Jüttner, Thomas Mentzel, Maja Cesen, Elke Pfaff, Michal Kunc, Stephan Forchhammer, Andrea Forschner, Ulrike Leiter-Stöppke, Thomas K. Eigentler, Dominik T. Schneider, Christopher Schroeder, Stephan Ossowski, Ines B. Brecht

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UV-radiation and MC1R germline mutations are risk factors for the development of conventional and spitzoid melanomas in children and adolescents von Liebmann, Alexandra, Admard, Jakob, Armeanu-Ebinger, Sorin, Wild, Hannah, Abele, Michael, Gschwind, Axel, Seibel-Kelemen, Olga, Seitz, Christian, Bonzheim, Irina, Riess, Olaf, Demidov, German, Sturm, Marc, Schadeck, Malou, Pogoda, Michaela, Bien, Ewa, Krawczyk, Malgorzata, Jüttner, Eva, Mentzel, Thomas, Cesen, Maja, Pfaff, Elke, Kunc, Michal, Forchhammer, Stephan, Forschner, Andrea, Leiter-Stöppke, Ulrike, Eigentler, Thomas K., Schneider, Dominik T., Schroeder, Christopher, Ossowski, Stephan, Brecht, Ines B.

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Clinical outcome of biomarker-guided therapies in adult patients with tumors of the nervous system von Renovanz, Mirjam, Kurz, Sylvia C, Rieger, Johannes, Walter, Bianca, Becker, Hannes, Hille, Hanni, Bombach, Paula, Rieger, David, Grosse, Lucia, Häusser, Lara, Skardelly, Marco, Merk, Daniel J, Paulsen, Frank, Hoffmann, Elgin, Gani, Cihan, Neumann, Manuela, Beschorner, Rudi, Rieß, Olaf, Roggia, Cristiana, Schroeder, Christopher, Ossowski, Stephan, Armeanu-Ebinger, Sorin, Gschwind, Axel, Biskup, Saskia, Schulze, Martin, Fend, Falko, Singer, Stephan, Zender, Lars, Lengerke, Claudia, Brucker, Sara Yvonne, Engler, Tobias, Forschner, Andrea, Stenzl, Arnulf, Kohlbacher, Oliver, Nahnsen, Sven, Gabernet, Gisela, Fillinger, Sven, Bender, Benjamin, Ernemann, Ulrike, Öner, Öznur, Beha, Janina, Malek, Holly Sundberg, Möller, Yvonne, Ruhm, Kristina, Tatagiba, Marcos, Schittenhelm, Jens, Bitzer, Michael, Malek, Nisar, Zips, Daniel, Tabatabai, Ghazaleh

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Inhibition of TACE or amphiregulin for the modulation of EGF receptor signal transactivation von ULLRICH AXEL,GSCHWIND ANDREAS,HART STEFAN

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Access to Benzo‐ and Naphtho‐Azaphospholes via C−H Bond Activation of Aryl‐Substituted Isonitriles von Pilopp, Yannic, Bresien, Jonas, Gschwind, Daniel T., Villinger, Alexander, Michalik, Dirk, Schulz, Axel

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The discovery of receptor tyrosine kinases: targets for cancer therapy von Ullrich, Axel, Gschwind, Andreas, Fischer, Oliver M

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TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells von Ullrich, Axel, Gschwind, Andreas, Hart, Stefan, Fischer, Oliver M

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Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion von SCHÄFER, Beatrix, GSCHWIND, Andreas, ULLRICH, Axel

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Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission von Gschwind, A, Zwick, E, Prenzel, N, Leserer, M, Ullrich, A

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Distinct ADAM Metalloproteinases Regulate G Protein-coupled Receptor-induced Cell Proliferation and Survival von Schäfer, Beatrix, Marg, Beatrice, Gschwind, Andreas, Ullrich, Axel

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Oxidative and Osmotic Stress Signaling in Tumor Cells Is Mediated by ADAM Proteases and Heparin-Binding Epidermal Growth Factor von Fischer, Oliver M., Hart, Stefan, Gschwind, Andreas, Prenzel, Norbert, Ullrich, Axel

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Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation von GSCHWIND, Andreas, PRENZEL, Norbert, ULLRICH, Axel

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Regional Patterns of Late Medieval and Early Modern European Building Activity Revealed by Felling Dates von Ljungqvist, Fredrik Charpentier, Seim, Andrea, Tegel, Willy, Krusic, Paul J., Baittinger, Claudia, Belingard, Christelle, Bernabei, Mauro, Bonde, Niels, Borghaerts, Paul, Couturier, Yann, Crone, Anne, van Daalen, Sjoerd, Daly, Aoife, Doeve, Petra, Domínguez-Delmás, Marta, Edouard, Jean-Louis, Frank, Thomas, Ginzler, Christian, Grabner, Michael, Gschwind, Friederike M., Haneca, Kristof, Hansson, Anton, Herzig, Franz, Heussner, Karl-Uwe, Hofmann, Jutta, Houbrechts, David, Kaczka, Ryszard J., Kolář, Tomáš, Kontic, Raymond, Kyncl, Tomáš, Labbas, Vincent, Lagerås, Per, Le Digol, Yannick, Le Roy, Melaine, Leuschner, Hanns Hubert, Linderson, Hans, Ludlow, Francis, Marais, Axel, Mills, Coralie M., Neyses-Eiden, Mechthild, Nicolussi, Kurt, Perrault, Christophe, Pfeifer, Klaus, Rybníček, Michal, Rzepecki, Andreas, Schmidhalter, Martin, Seifert, Mathias, Shindo, Lisa, Spyt, Barbara, Susperregi, Josué, Svarva, Helene Løvstrand, Thun, Terje, Walder, Felix, Ważny, Tomasz, Werthe, Elise, Westphal, Thorsten, Wilson, Rob, Büntgen, Ulf

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