Human adipose mesenchymal stem cells modulate myeloid cells toward an anti-inflammatory and reparative phenotype: role of IL-6 and PGE2 von Ortiz-Virumbrales, Maitane, Menta, Ramón, Pérez, Laura M, Lucchesi, Ornella, Mancheño-Corvo, Pablo, Avivar-Valderas, Álvaro, Palacios, Itziar, Herrero-Mendez, Angel, Dalemans, Wilfried, de la Rosa, Olga, Lombardo, Eleuterio

Volltext

A human tRNA methyltransferase 9‐like protein prevents tumour growth by regulating LIN9 and HIF1‐α von Begley, Ulrike, Sosa, Maria Soledad, Avivar‐Valderas, Alvaro, Patil, Ashish, Endres, Lauren, Estrada, Yeriel, Chan, Clement T.Y., Su, Dan, Dedon, Peter C., Aguirre‐Ghiso, Julio A., Begley, Thomas

Volltext

Mechanism of early dissemination and metastasis in Her2+ mammary cancer von Harper, Kathryn L., Sosa, Maria Soledad, Entenberg, David, Hosseini, Hedayatollah, Cheung, Julie F., Nobre, Rita, Avivar-Valderas, Alvaro, Nagi, Chandandaneep, Girnius, Nomeda, Davis, Roger J., Farias, Eduardo F., Condeelis, John, Klein, Christoph A., Aguirre-Ghiso, Julio A.

Volltext

PERK Integrates Autophagy and Oxidative Stress Responses To Promote Survival during Extracellular Matrix Detachment von Avivar-Valderas, Alvaro, Salas, Eduardo, Bobrovnikova-Marjon, Ekaterina, Diehl, J. Alan, Nagi, Chandandeep, Debnath, Jayanta, Aguirre-Ghiso, Julio A.

Volltext

Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer von Kim, Ryung S, Avivar-Valderas, Alvaro, Estrada, Yeriel, Bragado, Paloma, Sosa, Maria Soledad, Aguirre-Ghiso, Julio A, Segall, Jeffrey E

Volltext

Inhibiting PI3Kβ with AZD8186 Regulates Key Metabolic Pathways in PTEN-Null Tumors von Lynch, James T, Polanska, Urszula M, Delpuech, Oona, Hancox, Urs, Trinidad, Antonio G, Michopoulos, Filippos, Lenaghan, Carol, McEwen, Robert, Bradford, James, Polanski, Radek, Ellston, Rebecca, Avivar-Valderas, Alvaro, Pilling, James, Staniszewska, Anna, Cumberbatch, Marie, Critchlow, Susan E, Cruzalegui, Francisco, Barry, Simon T

Volltext

Dissecting Allo-Sensitization After Local Administration of Human Allogeneic Adipose Mesenchymal Stem Cells in Perianal Fistulas of Crohn's Disease Patients von Avivar-Valderas, Alvaro, Martín-Martín, Cristina, Ramírez, Cristina, Del Río, Borja, Menta, Ramón, Mancheño-Corvo, Pablo, Ortiz-Virumbrales, Maitane, Herrero-Méndez, Ángel, Panés, Julián, García-Olmo, Damián, Castañer, José Luís, Palacios, Itziar, Lombardo, Eleuterio, Dalemans, Wilfried, DelaRosa, Olga

Volltext

Epithelial Xbp1 Is Required for Cellular Proliferation and Differentiation during Mammary Gland Development von Hasegawa, Daisuke, Calvo, Veronica, Avivar-Valderas, Alvaro, Lade, Abigale, Chou, Hsin-I, Lee, Youngmin A., Farias, Eduardo F., Aguirre-Ghiso, Julio A., Friedman, Scott L.

Volltext

Analysis of marker-defined HNSCC subpopulations reveals a dynamic regulation of tumor initiating properties von Bragado, Paloma, Estrada, Yeriel, Sosa, Maria Soledad, Avivar-Valderas, Alvaro, Cannan, David, Genden, Eric, Teng, Marita, Ranganathan, Aparna C, Wen, Huei-Chi, Kapoor, Avnish, Bernstein, Emily, Aguirre-Ghiso, Julio A

Volltext

Autophagy and Tumor Cell Dormancy in Head and Neck Cancer von Jang, David W., Avivar-Valderas, Alvaro, Banach, Anna, Aguirre-Ghiso, Julio

Volltext

Human papillomavirus-16 E7 interacts with siva-1 and modulates apoptosis in HaCaT human immortalized keratinocytes von Severino, Anna, Abbruzzese, Claudia, Manente, Lucrezia, Valderas, Álvaro Avivar, Mattarocci, Stefano, Federico, Antonio, Starace, Giuseppe, Chersi, Alberto, Mileo, Anna Maria, Paggi, Marco G.

Volltext

Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments von Fluegen, Georg, Avivar-Valderas, Alvaro, Wang, Yarong, Padgen, Michael R., Williams, James K., Nobre, Ana Rita, Calvo, Veronica, Cheung, Julie F., Bravo-Cordero, Jose Javier, Entenberg, David, Castracane, James, Verkhusha, Vladislav, Keely, Patricia J., Condeelis, John, Aguirre-Ghiso, Julio A.

Volltext

ERK1/2 and p38α/β Signaling in Tumor Cell Quiescence: Opportunities to Control Dormant Residual Disease von SOSA, Maria Soledad, AVIVAR-VALDERAS, Alvaro, BRAGADO, Paloma, WEN, Huei-Chi, AGUIRRE-GHISO, Julio A

Volltext

Apoptosis in mesenchymal stromal cells activates an immunosuppressive secretome predicting clinical response in Crohn’s disease von Cheung, Tik Shing, Giacomini, Chiara, Cereda, Matteo, Avivar-Valderas, Alvaro, Capece, Daria, Bertolino, Giuliana Minani, delaRosa, Olga, Hicks, Ryan, Ciccocioppo, Rachele, Franzoso, Guido, Galleu, Antonio, Ciccarelli, Francesca D., Dazzi, Francesco

Volltext

Abstract 5285: PERK regulates autophagy and survival of luminal cells during mammary acinar morphogenesis von Avivar-Valderas, Alvaro

Volltext

Functional significance of co-occurring mutations in PIK3CA and MAP3K1 in breast cancer von Avivar-Valderas, Alvaro, McEwen, Robert, Taheri-Ghahfarokhi, Amir, Carnevalli, Larissa S, Hardaker, Elizabeth L, Maresca, Marcello, Hudson, Kevin, Harrington, Elizabeth A, Cruzalegui, Francisco

Volltext

Correction: Corrigendum: Mechanism of early dissemination and metastasis in Her2.sup.+ mammary cancer von Harper, Kathryn L, Sosa, Maria Soledad, Entenberg, David, Hosseini, Hedayatollah, Cheung, Julie F, Nobre, Rita, Avivar-Valderas, Alvaro

Volltext

Combined Inhibition of PI3Kβ and mTOR Inhibits Growth of PTEN-null Tumors von Lynch, James T, Polanska, Urszula M, Hancox, Ursula, Delpuech, Oona, Maynard, Juliana, Trigwell, Catherine, Eberlein, Catherine, Lenaghan, Carol, Polanski, Radoslaw, Avivar-Valderas, Alvaro, Cumberbatch, Marie, Klinowska, Teresa, Critchlow, Susan E, Cruzalegui, Francisco, Barry, Simon T

Volltext

Intermittent High-Dose Scheduling of AZD8835, a Novel Selective Inhibitor of PI3Kα and PI3Kδ, Demonstrates Treatment Strategies for PIK3CA-Dependent Breast Cancers von Hudson, Kevin, Hancox, Urs J, Trigwell, Cath, McEwen, Robert, Polanska, Urszula M, Nikolaou, Myria, Morentin Gutierrez, Pablo, Avivar-Valderas, Alvaro, Delpuech, Oona, Dudley, Phillippa, Hanson, Lyndsey, Ellston, Rebecca, Jones, Alys, Cumberbatch, Marie, Cosulich, Sabina C, Ward, Lara, Cruzalegui, Francisco, Green, Stephen

Volltext

Abstract 240: Functional significance of co-occurring mutations in PIK3CA and MAP3K1 in breast cancer von Avivar-Valderas, Alvaro, McEwen, Robert, Taheri-Ghahfarokhi, Amir, Ahmed, Ambar, Stetson, Daniel, Dougherty, Brian, Maresca, Marcello, Hudson, Kevin, Cruzalegui, Francisco

Volltext