Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis von Kim, Michael P., Li, Xinqun, Deng, Jenying, Zhang, Yun, Dai, Bingbing, Allton, Kendra L., Hughes, Tara G., Siangco, Christian, Augustine, Jithesh J., Kang, Ya'an, McDaniel, Joy M., Xiong, Shunbin, Koay, Eugene J., McAllister, Florencia, Bristow, Christopher A., Heffernan, Timothy P., Maitra, Anirban, Liu, Bin, Barton, Michelle C., Wasylishen, Amanda R., Fleming, Jason B., Lozano, Guillermina

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Compound NSC84167 selectively targets NRF2-activated pancreatic cancer by inhibiting asparagine synthesis pathway von Dai, Bingbing, Augustine, Jithesh J., Kang, Ya’an, Roife, David, Li, Xinqun, Deng, Jenying, Tan, Lin, Rusling, Leona A., Weinstein, John N., Lorenzi, Philip L., Kim, Michael P., Fleming, Jason B.

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Antineoplastic effects of auranofin in human pancreatic adenocarcinoma preclinical models von Rios Perez, Mayrim V., Roife, David, Dai, Bingbing, Pratt, Michael, Dobrowolski, Ryszard, Kang, Ya'an, Li, Xinqun, Augustine, Jithesh J., Zielinski, Rafal, Priebe, Waldemar, Fleming, Jason B.

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MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer von Shukla, Surendra K., Purohit, Vinee, Mehla, Kamiya, Gunda, Venugopal, Chaika, Nina V., Vernucci, Enza, King, Ryan J., Abrego, Jaime, Goode, Gennifer D., Dasgupta, Aneesha, Illies, Alysha L., Gebregiworgis, Teklab, Dai, Bingbing, Augustine, Jithesh J., Murthy, Divya, Attri, Kuldeep S., Mashadova, Oksana, Grandgenett, Paul M., Powers, Robert, Ly, Quan P., Lazenby, Audrey J., Grem, Jean L., Yu, Fang, Matés, José M., Asara, John M., Kim, Jung-whan, Hankins, Jordan H., Weekes, Colin, Hollingsworth, Michael A., Serkova, Natalie J., Sasson, Aaron R., Fleming, Jason B., Oliveto, Jennifer M., Lyssiotis, Costas A., Cantley, Lewis C., Berim, Lyudmyla, Singh, Pankaj K.

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MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer von Shukla, Surendra K., Purohit, Vinee, Mehla, Kamiya, Gunda, Venugopal, Chaika, Nina V., Vernucci, Enza, King, Ryan J., Abrego, Jaime, Goode, Gennifer D., Dasgupta, Aneesha, Illies, Alysha L., Gebregiworgis, Teklab, Dai, Bingbing, Augustine, Jithesh J., Murthy, Divya, Attri, Kuldeep S., Mashadova, Oksana, Grandgenett, Paul M., Powers, Robert, Ly, Quan P., Lazenby, Audrey J., Grem, Jean L., Yu, Fang, Matés, José M., Asara, John M., Kim, Jung-whan, Hankins, Jordan H., Weekes, Colin, Hollingsworth, Michael A., Serkova, Natalie J., Sasson, Aaron R., Fleming, Jason B., Oliveto, Jennifer M., Lyssiotis, Costas A., Cantley, Lewis C., Berim, Lyudmyla, Singh, Pankaj K.

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Abstract 4786: BP1003, a novel liposome-incorporated STAT3 antisense oligodeoxynucleotide inhibitor von Dai, Bingbing, Ashizawa, Ana Tari, Augustine, Jithesh J., Kim, Michael, Fleming, Jason

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Clinical candidate and genistein analogue AXP107‐11 has chemoenhancing functions in pancreatic adenocarcinoma through G protein‐coupled estrogen receptor signaling von Mesmar, Fahmi, Dai, Bingbing, Ibrahim, Ahmed, Hases, Linnea, Jafferali, Mohammed Hakim, Jose Augustine, Jithesh, DiLorenzo, Sebastian, Kang, Ya'an, Zhao, Yang, Wang, Jing, Kim, Michael, Lin, Chin‐Yo, Berkenstam, Anders, Fleming, Jason, Williams, Cecilia

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Abstract 4732: CDK4/6 inhibition with lerociclib (G1T38) enhances response to PI3K or ERK inhibitors in high-throughput, ex vivo pancreatic PDX screens von Dai, Bingbing, Freed, Daniel M., Sorrentino, Jessica A., Augustine, Jithesh Jose, Hughes, Tara G., Kang, Ya'an, Roberts, Patrick J., Fleming, Jason B., Kim, Michael P.

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Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment von Sun, Hua, Cao, Song, Mashl, R. Jay, Mo, Chia-Kuei, Zaccaria, Simone, Wendl, Michael C., Davies, Sherri R., Bailey, Matthew H., Primeau, Tina M., Hoog, Jeremy, Mudd, Jacqueline L., Dean, Dennis A., Patidar, Rajesh, Chen, Li, Wyczalkowski, Matthew A., Jayasinghe, Reyka G., Rodrigues, Fernanda Martins, Terekhanova, Nadezhda V., Li, Yize, Lim, Kian-Huat, Wang-Gillam, Andrea, Van Tine, Brian A., Ma, Cynthia X., Aft, Rebecca, Fuh, Katherine C., Schwarz, Julie K., Zevallos, Jose P., Puram, Sidharth V., Dipersio, John F., Davis-Dusenbery, Brandi, Ellis, Matthew J., Lewis, Michael T., Davies, Michael A., Herlyn, Meenhard, Fang, Bingliang, Roth, Jack A., Welm, Alana L., Welm, Bryan E., Meric-Bernstam, Funda, Chen, Feng, Fields, Ryan C., Li, Shunqiang, Govindan, Ramaswamy, Doroshow, James H., Moscow, Jeffrey A., Evrard, Yvonne A., Chuang, Jeffrey H., Raphael, Benjamin J., Ding, Li

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Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment von Sun, Hua, Cao, Song, Mashl, R. Jay, Mo, Chia-Kuei, Zaccaria, Simone, Wendl, Michael C., Davies, Sherri R., Bailey, Matthew H., Primeau, Tina M., Hoog, Jeremy, Mudd, Jacqueline L., Dean, Dennis A., Patidar, Rajesh, Chen, Li, Wyczalkowski, Matthew A., Jayasinghe, Reyka G., Rodrigues, Fernanda Martins, Terekhanova, Nadezhda V., Li, Yize, Lim, Kian-Huat, Wang-Gillam, Andrea, Van Tine, Brian A., Ma, Cynthia X., Aft, Rebecca, Fuh, Katherine C., Schwarz, Julie K., Zevallos, Jose P., Puram, Sidharth V., Dipersio, John F., Davis-Dusenbery, Brandi, Ellis, Matthew J., Lewis, Michael T., Davies, Michael A., Herlyn, Meenhard, Fang, Bingliang, Roth, Jack A., Welm, Alana L., Welm, Bryan E., Meric-Bernstam, Funda, Chen, Feng, Fields, Ryan C., Li, Shunqiang, Govindan, Ramaswamy, Doroshow, James H., Moscow, Jeffrey A., Evrard, Yvonne A., Chuang, Jeffrey H., Raphael, Benjamin J., Ding, Li

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PDXNet portal: patient-derived Xenograft model, data, workflow and tool discovery von Koc, Soner, Lloyd, Michael W, Grover, Jeffrey W, Xiao, Nan, Seepo, Sara, Subramanian, Sai Lakshmi, Ray, Manisha, Frech, Christian, DiGiovanna, John, Webster, Phillip, Neuhauser, Steven, Srivastava, Anuj, Woo, Xing Yi, Sanderson, Brian J, White, Brian, Lott, Paul, Dobrolecki, Lacey E, Dowst, Heidi, Evrard, Yvonne A, Wallace, Tiffany A, Moscow, Jeffrey A, Doroshow, James H, Mitsiades, Nicholas, Kaochar, Salma, Pan, Chong-Xian, Chen, Moon S, Carvajal-Carmona, Luis, Welm, Alana L, Welm, Bryan E, Lewis, Michael T, Govindan, Ramaswamy, Ding, Li, Li, Shunqiang, Herlyn, Meenhard, Davies, Michael A, Roth, Jack, Meric-Bernstam, Funda, Robinson, Peter N, Bult, Carol J, Davis-Dusenbery, Brandi, Dean, 2nd, Dennis A, Chuang, Jeffrey H

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