443: CONTINUOUS INTRAVENOUS VS SUBCUTANEOUS INSULIN MANAGEMENT IN MILD TO MODERATE DIABETIC KETOACIDOSIS von Cortes, Jennifer, Augustine, Annette, Hartman, Heather, Ibanez, Kasaandra, Pelsue, Brittany

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Hospitalization Provides An Opportunity For Sacubitril/valsartan Initiation von Smith, Adam, Augustine, Annette, Crawford, Katherine, Schreck, Tara, Basuray, Anupam

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Early Identification of Patients at Risk of Acute Lung Injury: Evaluation of Lung Injury Prediction Score in a Multicenter Cohort Study von GAJIC, Ognjen, DABBAGH, Ousama, GONG, Michelle N, TALMOR, Daniel, BAJWA, Ednan, WATKINS, Timothy R, FESTIC, Emir, YILMAZ, Murat, ISCIMEN, Remzi, KAUFMAN, David A, ESPER, Annette M, SADIKOT, Ruxana, PARK, Pauline K, DOUGLAS, Ivor, SEVRANSKY, Jonathan, MALINCHOC, Michael, ADESANYA, Adebola, CHANG, Steven Y, HOU, Peter, ANDERSON, Harry, HOTH, J. Jason, MIKKELSEN, Mark E, GENTILE, Nina T

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Morphological score assignment guidelines for the dechorionated zebrafish teratogenicity assay von Panzica-Kelly, Julieta M., Zhang, Cindy X., Danberry, Tracy L., Flood, Annette, DeLan, Judiann W., Brannen, Kimberly C., Augustine-Rauch, Karen A.

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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk von Ehret, Georg B, Munroe, Patricia B, Rice, Kenneth M, Bochud, Murielle, Johnson, Andrew D, Chasman, Daniel I, Smith, Albert V, Tobin, Martin D, Verwoert, Germaine C, Hwang, Shih-Jen, Pihur, Vasyl, Vollenweider, Peter, O'Reilly, Paul F, Amin, Najaf, Bragg-Gresham, Jennifer L, Teumer, Alexander, Glazer, Nicole L, Launer, Lenore, Zhao, Jing Hua, Aulchenko, Yurii, Heath, Simon, Sõber, Siim, Parsa, Afshin, Luan, Jian'an, Arora, Pankaj, Dehghan, Abbas, Zhang, Feng, Lucas, Gavin, Hicks, Andrew A, Jackson, Anne U, Peden, John F, Tanaka, Toshiko, Wild, Sarah H, Rudan, Igor, Igl, Wilmar, Milaneschi, Yuri, Parker, Alex N, Fava, Cristiano, Chambers, John C, Fox, Ervin R, Kumari, Meena, Go, Min Jin, van der Harst, Pim, Kao, Wen Hong Linda, Sjögren, Marketa, Vinay, D G, Alexander, Myriam, Tabara, Yasuharu, Shaw-Hawkins, Sue, Whincup, Peter H, Liu, Yongmei, Shi, Gang, Kuusisto, Johanna, Tayo, Bamidele, Seielstad, Mark, Sim, Xueling, Nguyen, Khanh-Dung Hoang, Lehtimäki, Terho, Matullo, Giuseppe, Wu, Ying, Gaunt, Tom R, Onland-Moret, N Charlotte, Cooper, Matthew N, Platou, Carl G P, Org, Elin, Hardy, Rebecca, Dahgam, Santosh, Palmen, Jutta, Vitart, Veronique, Braund, Peter S, Kuznetsova, Tatiana, Uiterwaal, Cuno S P M, Adeyemo, Adebowale, Palmas, Walter, Campbell, Harry, Ludwig, Barbara, Tomaszewski, Maciej, Tzoulaki, Ioanna, Palmer, Nicholette D, Aspelund, Thor, Garcia, Melissa, Chang, Yen-Pei C, O'Connell, Jeffrey R, Steinle, Nanette I, Grobbee, Diederick E, Arking, Dan E, Kardia, Sharon L, Morrison, Alanna C, Hernandez, Dena, Najjar, Samer, McArdle, Wendy L, Hadley, David, Brown, Morris J, Connell, John M, Hingorani, Aroon D, Day, Ian N M, Lawlor, Debbie A, Beilby, John P, Lawrence, Robert W, Clarke, Robert

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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility von Below, Jennifer E, Horikoshi, Momoko, Johnson, Andrew D, Ng, Maggie C Y, Abecasis, Goncalo R, Been, Latonya F, Caulfield, Mark, Chang, Li-Ching, Chang, Tien-Jyun, Chang, Yi-Cheng, Chen, Chien-Hsiun, Chen, Han, Chidambaram, Manickam, Cho, Young Min, Collins, Francis S, Das, Debashish, Dedoussis, George, Dimas, Antigone S, Doney, Alex S F, Dorkhan, Mozhgan, Edkins, Sarah, Erbel, Raimund, Fontanillas, Pierre, Fox, Caroline, Froguel, Philippe, Gao, Yutang, Gieger, Christian, Gigante, Bruna, Grallert, Harald, Guiducci, Candace, Hamsten, Anders, Hattersley, Andrew T, Hayward, Caroline, Herder, Christian, Hofman, Albert, Holmen, Oddgeir L, Humphries, Steve E, Hydrie, Zafar I, Jackson, Anne U, Jia, Weiping, Kato, Norihiro, Kelly, Ann M, Khan, Hassan, Kim, Hyung-Lae, Kong, Augustine, Korpi-Hyövälti, Eeva, Kumar, Ashish, Laakso, Markku, Langenberg, Claudia, Li, Man, Li, Xinzhong, Li, Yun, Liang, Junbin, Liju, Samuel, Lind, Lars, Lindgren, Cecilia M, Lobbens, Stéphane, Lu, Wei, Luan, Jian'an, Lyssenko, Valeriya, Männistö, Satu, Meigs, James B, Meyer, Julia, Mohlke, Karen L, Musk, Bill, Nakamura, Jiro, Park, Kyong Soo, Rallidis, Loukianos, Rasheed, Asif, Rehnberg, Emil, Rudan, Igor, Rybin, Denis, Saaristo, Timo E, Sanghera, Dharambir K, Saramies, Jouko, Scott, Robert A, Shah, Nabi, Sim, Xueling, Sivapalaratnam, Suthesh, Stančáková, Alena, Steinthorsdottir, Valgerdur, Stirrups, Kathleen, Strawbridge, Rona J, Takeuchi, Fumihiko, Thorsteinsdottir, Unnur, Trip, Mieke D, Valladares-Salgado, Adan, Wang, Congrong, Wickremasinghe, Ananda R, Wu, Ying, Yamamoto, Ken, Yang, Mingyu, Young, Robin, Zhang, Fan, Zhang, Rong, Altshuler, David, Cho, Yoon Shin, Lee, Jong-Young, Teo, Yik Ying, Boehnke, Michael

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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease von Schunkert, Heribert, Kathiresan, Sekar, Stewart, Alexandre F R, Barbalic, Maja, Absher, Devin, Aherrahrou, Zouhair, Allayee, Hooman, Anand, Sonia S, Anderson, Jeffrey L, Ardissino, Diego, Balmforth, Anthony J, Boerwinkle, Eric, Braund, Peter S, Brown, Morris J, Burnett, Mary Susan, Buysschaert, Ian, Carlquist, John F, Chen, Li, Cichon, Sven, Davies, Robert W, Dehghan, Abbas, Demissie, Serkalem, Do, Ron, Eifert, Sandra, Mokhtari, Nour Eddine El, Elosua, Roberto, Engert, James C, Epstein, Stephen E, Fischer, Marcus, Folsom, Aaron R, Freyer, Jennifer, Halperin, Eran, Hammond, Naomi, Hazen, Stanley L, Horne, Benjamin D, Illig, Thomas, Iribarren, Carlos, Kaiser, Michael A, Kaplan, Lee M, Kastelein, John J P, Laaksonen, Reijo, Leander, Karin, Lettre, Guillaume, Li, Mingyao, Loley, Christina, Lotery, Andrew J, Mannucci, Pier M, Maouche, Seraya, Martinelli, Nicola, Meisinger, Christa, Melander, Olle, Mooser, Vincent, Mühleisen, Thomas W, Münzel, Thomas, Musunuru, Kiran, Nelson, Christopher P, Nöthen, Markus M, Olivieri, Oliviero, Patel, Riyaz S, Patterson, Chris C, Peters, Annette, Peyvandi, Flora, Quyyumi, Arshed A, Rallidis, Loukianos S, Rice, Catherine, Rosendaal, Frits R, Salomaa, Veikko, Sampietro, M Lourdes, Schäfer, Arne, Schillert, Arne, Schreiber, Stefan, Schrezenmeir, Jürgen, Schwartz, Stephen M, Sivananthan, Mohan, Smith, Albert, Smith, Tamara B, Snoep, Jaapjan D, Soranzo, Nicole, Spertus, John A, Stark, Klaus, Stirrups, Kathy, Stoll, Monika, Tang, W H Wilson, Thorgeirsson, Gudmundur, Thorleifsson, Gudmar, van Rij, Andre M, Wells, George A, Wichmann, H-Erich, Wild, Philipp S, Willenborg, Christina, Zeller, Tanja, Ziegler, Andreas, Cambien, Francois, Hengstenberg, Christian, Blankenberg, Stefan, Ouwehand, Willem H, Hall, Alistair S, Thompson, John R, McPherson, Ruth, Erdmann, Jeanette

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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci von Reschen, Michael E, Mahajan, Anubha, William Rayner, N, Scott, Laura J, Yengo, Loic, Wahl, Simone, Kestler, Hans, Chheda, Himanshu, Eisele, Lewin, Steinthorsdottir, Valgerdur, Chen, Han, Fuchsberger, Christian, Kwan, Phoenix, Thomsen, Soren K, Rundle, Jana K, van de Bunt, Martijn, Voight, Benjamin F, Abecasis, Gonçalo R, Baldassarre, Damiano, Carey, Jason, Chines, Peter S, Crenshaw, Andrew T, Edkins, Sarah, Eury, Elodie, Fontanillas, Pierre, Franks, Paul W, Gertow, Karl, Groves, Christopher J, Hassinen, Maija, Herder, Christian, Hreidarsson, Astradur B, Jackson, Anne U, Jonsson, Anna, Jørgensen, Marit E, Jørgensen, Torben, Kao, Wen-Hong L, Kerrison, Nicola D, Kinnunen, Leena, Kravic, Jasmina, Langford, Cordelia, Lichtner, Peter, Lindholm, Eero, Lobbens, Stéphane, Luan, Jian'an, Meyer, Julia, Mihailov, Evelin, Mühleisen, Thomas W, Navarro, Carmen, Oskolkov, Nikolay N, Pechlivanis, Sonali, Platou, Carl G P, Rybin, Denis, van der Schouw, Yvonne T, Sennblad, Bengt, Steinbach, Gerald, Storm, Petter, Sun, Qi, Thorand, Barbara, Tikkanen, Emmi, Trakalo, Joseph, Tremoli, Elena, Wood, Andrew R, Zeggini, Eleftheria, Birney, Ewan, Pasquali, Lorenzo, Pankow, James S, van Duijn, Cornelia, Sijbrands, Eric, Hu, Frank B, Thorsteinsdottir, Unnur, Stefansson, Kari, Lakka, Timo A, Rauramaa, Rainer, Stumvoll, Michael, Korpi-Hyövälti, Eeva, Kuusisto, Johanna, Metspalu, Andres, Jöcke, Karl-Heinz, Moebus, Susanne, Bergman, Richard N, Collins, Francis S, Mohlke, Karen L, Koistinen, Heikki, Tuomilehto, Jaakko, Deloukas, Panagiotis, Donnelly, Peter J, Frayling, Timothy M, Sladek, Rob, Froguel, Philippe, Hansen, Torben, Kathiresan, Sekar, Barroso, Inês, Langenberg, Claudia, Wareham, Nicholas J, O'Callaghan, Christopher A, Gloyn, Anna L, Altshuler, David, Boehnke, Michael, Teslovich, Tanya M, Morris, Andrew P

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Biotransformation and Oxidative Stress Responses in Captive Nile Crocodile (Crocodylus niloticus) Exposed to Organic Contaminants from the Natural Environment in South Africa von Arukwe, Augustine, Røsbak, Randi, Adeogun, Aina O, Langberg, Håkon A, Venter, Annette, Myburgh, Jan, Botha, Christo, Benedetti, Maura, Regoli, Francesco

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Common variants conferring risk of schizophrenia von Stefansson, Hreinn, Ophoff, Roel A., Steinberg, Stacy, Andreassen, Ole A., Cichon, Sven, Rujescu, Dan, Werge, Thomas, Pietiläinen, Olli P. H., Mors, Ole, Mortensen, Preben B., Sigurdsson, Engilbert, Gustafsson, Omar, Nyegaard, Mette, Tuulio-Henriksson, Annamari, Ingason, Andres, Hansen, Thomas, Suvisaari, Jaana, Lonnqvist, Jouko, Paunio, Tiina, Børglum, Anders D., Hartmann, Annette, Fink-Jensen, Anders, Nordentoft, Merete, Hougaard, David, Norgaard-Pedersen, Bent, Böttcher, Yvonne, Olesen, Jes, Breuer, René, Möller, Hans-Jürgen, Giegling, Ina, Rasmussen, Henrik B., Timm, Sally, Mattheisen, Manuel, Bitter, István, Réthelyi, János M., Magnusdottir, Brynja B., Sigmundsson, Thordur, Olason, Pall, Masson, Gisli, Gulcher, Jeffrey R., Haraldsson, Magnus, Fossdal, Ragnheidur, Thorgeirsson, Thorgeir E., Thorsteinsdottir, Unnur, Ruggeri, Mirella, Tosato, Sarah, Franke, Barbara, Strengman, Eric, Kiemeney, Lambertus A., Melle, Ingrid, Djurovic, Srdjan, Abramova, Lilia, Kaleda, Vasily, Sanjuan, Julio, de Frutos, Rosa, Bramon, Elvira, Vassos, Evangelos, Fraser, Gillian, Ettinger, Ulrich, Picchioni, Marco, Walker, Nicholas, Toulopoulou, Timi, Need, Anna C., Ge, Dongliang, Lim Yoon, Joeng, Shianna, Kevin V., Freimer, Nelson B., Cantor, Rita M., Murray, Robin, Kong, Augustine, Golimbet, Vera, Carracedo, Angel, Arango, Celso, Costas, Javier, Jönsson, Erik G., Terenius, Lars, Agartz, Ingrid, Petursson, Hannes, Nöthen, Markus M., Rietschel, Marcella, Matthews, Paul M., Muglia, Pierandrea, Peltonen, Leena, St Clair, David, Goldstein, David B., Stefansson, Kari, Collier, David A.

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Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort von Zhang, William Z, Rice, Michelle C, Hoffman, Katherine L, Oromendia, Clara, Barjaktarevic, Igor Z, Wells, J Michael, Hastie, Annette T, Labaki, Wassim W, Cooper, Christopher B, Comellas, Alejandro P, Criner, Gerard J, Krishnan, Jerry A, Paine, 3rd, Robert, Hansel, Nadia N, Bowler, Russell P, Barr, R Graham, Peters, Stephen P, Woodruff, Prescott G, Curtis, Jeffrey L, Han, Meilan K, Ballman, Karla V, Martinez, Fernando J, Choi, Augustine Mk, Nakahira, Kiichi, Cloonan, Suzanne M, Choi, Mary E

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α‐Arrestin regulation of protein trafficking: Using evolutionary rate covariation to define protein trafficking regulatory networks von Jordahl, Eric, Hedayati, Stefanie, Chiang, Annette, Kowalczyk, Amanda, Chen, Oscar, Finkelstein, Tova, Callahan, Kenny, Augustine, David, Malik, Abdullah, Nikiforov, Alexiy, Serbin, Hilary, Ferreria, Zelia, Clark, Nathan, O'Donnell, Allyson

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Induction of Fetal Hemoglobin and Reduction of Clinical Manifestations in Patients with Severe Sickle Cell Disease Treated with Shmir-Based Lentiviral Gene Therapy for Post-Transcr... von Esrick, Erica B., Federico, Amy, Abriss, Daniela, Armant, Myriam, Boardman, Kari, Brendel, Christian, Ciuculescu, Marioara-Felicia, Daley, Heather, Dansereau, Colleen, Fernandes, Augustine, Heeney, Matthew M., Justus, David G., Kao, Pei-Chi, Kim, Annette S., Kohn, Donald B., Lehmann, Leslie E., Liu, Donghui, London, Wendy B., Manis, John P, Moore, Theodore B., Morris, Emily, Pellin, Danilo, Proeung, Ellen, Richard, Shanna, Roach, Gavin D., Shaw, Kit L., Terrazas, Dayna, White, Shanna L, Williams, David A.

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Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1 von Bown, Matthew J., Jones, Gregory T., Harrison, Seamus C., Wright, Benjamin J., Bumpstead, Suzannah, Baas, Annette F., Gretarsdottir, Solveig, Badger, Stephen A., Bradley, Declan T., Burnand, Kevin, Child, Anne H., Clough, Rachel E., Cockerill, Gillian, Hafez, Hany, Scott, D. Julian A., Futers, Simon, Johnson, Anne, Sohrabi, Soroush, Smith, Alberto, Thompson, Matthew M., van Bockxmeer, Frank M., Waltham, Matthew, Matthiasson, Stefan E., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Blankensteijn, Jan D., Teijink, Joep A.W., Wijmenga, Cisca, de Graaf, Jacqueline, Kiemeney, Lambertus A., Assimes, Themistocles L., McPherson, Ruth, Folkersen, Lasse, Franco-Cereceda, Anders, Palmen, Jutta, Smith, Andrew J., Sylvius, Nicolas, Wild, John B., Refstrup, Mette, Edkins, Sarah, Gwilliam, Rhian, Hunt, Sarah E., Potter, Simon, Lindholt, Jes S., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Hughes, Anne E., Golledge, Jonathan, Norman, Paul E., van Rij, Andre, Powell, Janet T., Eriksson, Per, Stefansson, Kari, Thompson, John R., Humphries, Steve E., Sayers, Robert D., Deloukas, Panos, Samani, Nilesh J.

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Neonatal and Early Childhood Outcomes of Twin and Singleton Infants Born Preterm von Melamed, Nir, Weitzner, Omer, Church, Paige, Barrett, Jon, Piedboeuf, Bruno, Sherlock, Rebecca, Mehrem, Ayman Abou, Toye, Jennifer, Ting, Joseph, Fajardo, Carlos, Bodani, Jaya, Strueby, Lannae, Louis, Deepak, Alvaro, Ruben, Mukerji, Amit, Lee, Kyong-Soon, Ng, Eugene, Lemyre, Brigitte, Daboval, Thierry, Khurshid, Faiza, Bizgu, Victoria, Barrington, Keith, Lapointe, Anie, Ethier, Guillaume, Piedboeuf, Bruno, Claveau, Martine, Bertelle, Valerie, Masse, Edith, Mehdizadeh-Hakak, Hamid, Hudson, Jo-Anna, Lee, Shoo K., Abenhaim, Haim, Afifi, Jehier, Aziz, Khalid, Barrett, Jon, Blais, Lucie, Bocking, Alan, Burrows, Jason, Butt, Kimberly, Canning, Roderick, Carson, George, Cieslak, Zenon, Crane, Joan, de Cabo, Cecilia, Dow, Kimberly, Dunn, Michael, Helou, Salhab el, Foster, Jonathan, Gagnon, Robert, Gratton, Rob, Harrison, Adele, Helewa, Michael, Joseph, K.S., Kajetanowicz, Andrzej, Lacaze-Masmonteil, Thierry, Lodha, Abhay, Luu, Thuy Mai, Ly, Linh, Marc, Isabelle, McDonald, Sarah D., McMillan, Doug, Melamed, Nir, Moddemann, Diane, Murphy, Lynn, Murphy, Kellie, O'Brien, Karel, Ouellet, Annie, Pasquier, Jean-Charles, Pechlivanoglou, Petros, Pelausa, Ermelinda, Portales-Casamar, Elodie, Premji, Shahirose, Puligandla, Pramod, Pullenayegum, Eleanor, Robson, Kate, Schneider, Carol, Shah, Vibhuti, Skarsgard, Erik, Smith, Graeme, Thériault, Katherine, Ubhi, Jagdeep, Vincer, Michael, Whittle, Wendy, Wilson, Doug, Wood, Stephen, Ye, Philip, Yee, Wendy, Pillay, Thevanisha, Zwicker, Jill, Anson, Shelagh, Moodley, Anitha, Moddemann, Diane, McKnight, Sarah, Kelly, Edmond, Raghuram, Kamini, Thomas, Karen, Nguyen, Kim-Anh, Luu, Thuy Mai, Morin, Alyssa, Bélanger, Sylvie

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Cash transfers and nutrition education to improve dietary diversity among children aged 6–23 months in Grand Gedeh County, Liberia: a cluster-randomized trial von Rees, Chris A, Cleon, Dadah, Davis, Annette B, Sammy, Andrew M, Britto, Carl D, Massaquoi, Wesley, Forkpa, Oretha W, Johnson, Andrew J, Hook, Varla F, MaCauley, Jane A, Pewu, Garbie F, Gorpue, Mercy, Gborie, Amos, Brown, Trokon T, Fannieh, Augustine, Dweh, Teeline, Marley, Ruth B, Baysah, Massaboi K, Nowine, Netus N, Niescierenko, Michelle, Zaizay, Leela

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Association of prehospitalization aspirin therapy and acute lung injury: Results of a multicenter international observational study of at-risk patients von Kor, Daryl J, Erlich, Jason, Gong, Michelle N, Malinchoc, Michael, Carter, Rickey E, Gajic, Ognjen, Talmor, Daniel S

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The Influence of Prehospital Systemic Corticosteroid Use on Development of Acute Respiratory Distress Syndrome and Hospital Outcomes von Karnatovskaia, Lioudmila V, Lee, Augustine S, Gajic, Ognjen, Festic, Emir

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GENETIC DISSECTION OF SEVERITY AND ONSET MODULATORS FOR ALZHEIMER’S PATHOLOGY IN DOWN SYNDROME USING CELLULAR SYSTEMS von Murray, Aoife, Goh, Pollyanna, Yeap, Yee-Jie, Startin, Carla, Hamburg, Sarah, Hithersay, Rosalyn, d'Souza, Hana, Mok, Kin, Rovelet-Lecrux, Anne, Wallon, David, Choolani, Mahesh, Chan, Jerry, Botte, Alexandra, Potier, Marie-Claude, Augustine, George, Wiseman, Frances K., Fisher, Elizabeth, Tybulewicz, Victor L., Karmiloff-Smith, Annette, Strydom, Andre, Hardy, John, Groet, Jurgen, Nizetic, Dean

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Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort von Zhang, William Z, Rice, Michelle C, Hoffman, Katherine L, Oromendia, Clara, Barjaktarevic, Igor Z, Wells, J Michael, Hastie, Annette T, Labaki, Wassim W, Cooper, Christopher B, Comellas, Alejandro P, Criner, Gerard J, Krishnan, Jerry A, Paine, 3rd, Robert, Hansel, Nadia N, Bowler, Russell P, Barr, R Graham, Peters, Stephen P, Woodruff, Prescott G, Curtis, Jeffrey L, Han, Meilan K, Ballman, Karla V, Martinez, Fernando J, Choi, Augustine Mk, Nakahira, Kiichi, Cloonan, Suzanne M, Choi, Mary E

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